Korea Univ.

RNA Metabolism Lab.

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Welcome to the RNA Metabolism Laboratory.

The goal of our research is to understand how RNA processing regulates gene expression and cellular function. In particular, we are interested in alternative splicing, a process that allows a single gene to produce multiple transcript isoforms and greatly expands the complexity of the proteome.

Our laboratory studies how RNA-binding proteins such as RBFOX2 control splicing decisions and how alterations in RNA processing affect cellular signaling and disease progression. We combine molecular biology, genomics, and computational approaches to investigate RNA regulatory networks at a systems level.

Ultimately, our goal is to understand how dysregulated RNA processing contributes to human diseases, including cancer, and to provide new insights into gene regulation at the post-transcriptional level.