Commando is a balanced character that deals moderate damage. Commando's Phase Round is able to shoot through walls and its Suppressive Fire deals big damage while stalling enemy movement.
MUL-T is a character / class that works well in both single & coop. Holding two equipment at once, it can switch between rapid fire shots or heavy-damage bullets. It can dash forward to gain armor & speed while dealing damage to enemies it hits along the way.
Huntress is high DPS but with low health & defense. Huntress is able to use Strafe while sprinting and Laser Glaive can hit multiple enemies for up to 6 times. Arrow Rain slows enemies while dealing AoE damage aimed at a specific area.
Engineer is a character / class that requires strategic placement and timing of use of his tools. He is able to place mines to damage incoming enemies & implement a bubble shield to protect from enemy fire. His Gauss Turret provides good cover fire and adopts all his items.
Artificer deals big AoE elemental damage and specializes is dealing with large groups. Flame Bolt sets enemies on fire and Charged Nano-Bomb can deal AoE damage while stunning foes. Snapfreeze can freeze enemies with low health to death while Flamethrower can incinerate groups of targets instantly.
The Mercenary is one of the few melee oriented character in Risk of Rain 2. Laser Sword and Whirlwind specialize in high-damage sword attacks. Eviscerate will target the closest enemy, striking them repeatedly and making you vulnerable while this skill is active.