Publications

 Selected Publications (Featured Papers)

SCI/SCIE Publication List (First or Corresponding Author)

• Single-cell profiling of paired nasal brushing and tissue samples reveals distinct cellular landscapes and immune phenotypes

Kim G, Lee S, Koo MS, Moon S, Kim D, Cho HJ, Kim CH, Rha MS (correspondence)

Journal of Allergy and Clinical Immunology. In press. doi: 10.1016/j.jaci.2026.02.019 

• Unsupervised multidimensional phenotyping for personalized surgical treatment in obstructive sleep apnea

Kim D, Lee SJ, Rha MS#, Cho HJ# (correspondence)

Otolaryngology-Head and Neck Surgery. In press. doi: 10.1002/ohn.70165

• Distinct inflammatory features and nasal Th2 cell profiles in allergic patients with chronic rhinosinusitis

Bae H, Kim G, Lee S, Koo MS, Cho HJ, Kim CH, Rha MS (correspondence)

Rhinology. In press. doi: 10.4193/Rhin25.195

• Association of allergen signatures with individualized allergic phenotypes

Kim D, Cho HJ, Kim CH, Rha MS (correspondence)

Allergology International. 2026;75(1):150-157 

- Selected as “The Editor’s Choice” in Allergol Int 2026 Jan

• Prevalence and associated factors of olfactory and gustatory loss in patients with nasal septal deviation

Kim JY, Cho HJ, Kim CH, Rha MS (correspondence)

Clinical Otolaryngology. 2026;51(1):101-110

• Distinct profiles of patient-reported outcomes across allergen signatures in chronic rhinosinusitis

Kim D, Jung CM, Cho HJ, Kim CH, Rha MS (correspondence)

Life. 2025;15(12):1835

• Prognostic significance of preoperative diagnosis in sinonasal inverted papilloma: recurrence-free survival analysis

Eo TS*, Rha MS*, Kim CH, Cho HJ

European Archives of Otorhinolaryngology. 2025;282(8):4129-4137

• Epithelial lining fluid cystatin SN is a noninvasive biomarker for predicting type 2 chronic rhinosinusitis

Moon S*, Moon S*, Lee S, Kim G, Koo MS, Cho HJ, Kim CH, Rha MS (correspondence)

Allergy. 2025;80(9):2572-2585 

• A century of otorhinolaryngology at Yonsei University College of Medicine and engagement with US Missionaries

Moon IS*, Rha MS*, Yeo IS, Kim CH

Laryngoscope Investigative Otolaryngology. 2025;10(1):e70088

• Mucosal inflammatory memory in chronic rhinosinusitis

Koo MS*, Moon S*, Rha MS (correspondence)

Cells. 2024; 13(23):1947

• Revisiting T cells in chronic rhinosinusitis

Moon S, Rha MS (correspondence)

Allergy Asthma & Immunology Research. 2024;16(6):585-600

• Comparative analyses of post-infectious olfactory dysfunction between COVID-19 and non-COVID-19 cases

Eo TS, Jeong Y, Cho HJ, Rha MS#, Kim CH# (correspondence)

Scientific Reports. 2024;14(1):23511

• Outcomes and predictors of success following multilevel surgery in positional and non-positional obstructive sleep apnea

Noh HE*, Rha MS*, Jeong Y, Kim CH, Cho HJ

Otolaryngology-Head and Neck Surgery. 2024;171(5):1562-1571

• SARS-CoV-2 spike-specific nasal-resident CD49a+CD8+ memory T cells exert immediate effector functions with enhanced IFN-g production

Rha MS, Kim G, Lee S, Kim J, Jeong Y, Jung CM, Kim J, Noh HE, Lee HY, Noh JY, Kim YM, Cho HJ, Kim CH#, Shin EC#

Nature Communications. 2024;15(1):8355

• Sinonasal seromucinous hamartoma: A single institution case series combined with a narrative review of the literature

Kim CH, Cho HJ, Kim CH, Rha MS (correspondence)

European Archives of Otorhinolaryngology. 2024;281(10):5311–5317

• Type 1/17 CD103+CD4+ nasal-resident memory T cells in non-eosinophilic chronic rhinosinusitis with nasal polyps

Rha MS#, Kim G, Lee S, Jung CM, Lee YW, Noh HE, Jeong Y, Cho HJ, Kim CH# (correspondence)

Allergy. 2024;79(7):1996-1999

• Mucosal immunity against SARS-CoV-2 in the respiratory tract

Noh HE, Rha MS (correspondence)

Pathogens. 2024;13(2):113

• Impact of non-pharmaceutical interventions on the incidence and treatment of chronic rhinosinusitis during the COVID-19 pandemic: A nationwide retrospective cohort study

Jung CM*, Han M*, Cho HJ, Kim CH, Jung I#, Rha MS# (correspondence)

Journal of Clinical Medicine. 2023;12(20):6629

• Clinical characteristics and associated factors of qualitative olfactory dysfunction

Eo TS, Lee HY, Cho HJ, Yoon JH, Rha MS#, Kim CH# (correspondence)

Rhinology. 2023;61(5):432-440

• Clinical characteristics and surgical outcomes of obstructive sleep apnea patients with mixed apnea components

Rha MS, Jeong Y, Kim CH, Yoon JH, Cho HJ

Otolaryngology-Head and Neck Surgery. 2023;168(3):521-527

• Comparison of clinical features and surgical outcomes between hypopnea- and apnea-predominant obstructive sleep apnea

Rha MS, Jeong Y, Alyahya KA, Yoon JH, Kim CH, Cho HJ

Clinical Otolaryngology. 2023;48(2):167-174

• Identification of a distinct NK-like hepatic T-cell population activated by NKG2C in a TCR-independent manner

Koh JY*, Rha MS*, Choi SJ*, Lee HS, Han JW, Nam HJ, Kim DW, Lee JG, Kim MS, Park JY, Park SH#, Joo DJ#, Shin EC#

Journal of Hepatology. 2022;77(4):1059-1070

- Highlighted by “Intrahepatic T cells with NK-like properties: Expanding the repertoire of lymphocytes sensitive to bystander activation” in J Hepatol 2022 Oct 

• Gustatory dysfunction in patients with olfactory dysfunction and the associated factors

Rha MS, Cho HJ, Yoon JH, Moon SJ. Kim CH

Rhinology. 2022;60(3):200-206

• Is obstructive sleep apnea associated with erythrocytosis? A systematic review and meta-analysis

Rha MS, Jeong Y, Kim J, Kim CH, Yoon JH, Cho HJ

Laryngoscope Investigative Otolaryngology. 2022;7(2):627-635

• Impaired antibacterial response of liver sinusoidal Vγ9+Vδ2+ T cells in patients with chronic liver disease

Rha MS, Han JW, Koh JY, Lee HS, Kim JH, Cho KJ, Kim SI, Kim MS, Lee JG, Park SH, Joo DJ, Park JY#, Shin EC#

Gut. 2022;71(3):605-615

• Association between the use of electronic cigarettes and the prevalence of chronic rhinosinusitis and allergic rhinitis: a nationwide cross-sectional study

Rha MS, Cho HJ, Yoon JH, Kim CH

Rhinology. 2022;60(1):20-28

• Association of the human papillomavirus infection with the recurrence of sinonasal inverted papilloma: A systematic review and meta-analysis

Rha MS, Kim CH, Yoon JH, Cho HJ

Rhinology. 2022;60(1):2-10

• IL-17A-producing sinonasal MAIT cells in patients with chronic rhinosinusitis with nasal polyps

Rha MS, Yoon YH, Koh JY, Jung JH, Lee HS, Park SK, Park SH, Kim YM#, Rha KS#, Shin EC#

Journal of Allergy and Clinical Immunology. 2022;149(2):599-609.e7

- Selected as “The Editor’s Choice” in JACI 2022 Feb

• IFN-γ induces IL-15 trans-presentation by epithelial cells via IRF1

Kim TS*, Rha MS*, Shin EC

Journal of Immunology. 2022;208(2):338-346

• Activation or exhaustion of CD8+ T cells in patients with COVID-19

Rha MS, Shin EC

Cellular & Molecular Immunology. 2021;18(10):2325-2333

• Are electronic cigarettes harmful? Mucin may be the key

Rha MS, Kim CH

Clinical and Experimental Otorhinolaryngology. 2021;14(3):249-250

• SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells

Jung JH*, Rha MS*, Sa M, Choi HK, Jeon JH, Seok H, Park DW, Park SH, Jeong HW, Choi WS, Shin EC

Nature Communications. 2021;12(1):4043

- Selected as “2021 Top 25 COVID-19 Articles of Nature Communications”

• SARS-CoV-2-specific T cell responses in patients with COVID-19 and unexposed individuals

Rha MS*, Kim AR*, Shin EC

Immune Network. 2021;21(1):e2

• PD-1-expressing SARS-CoV-2-specific CD8+ T cells are not exhausted, but functional in patients with COVID-19

Rha MS*, Jeong HW*, Ko JH*, Choi SJ, Seo IH, Lee JS, Sa M, Kim AR, Joo EJ, Ahn JY, Kim JH, Song KH, Kim ES, Oh DH, Ahn MY, Choi HK, Jeon JH, Choi JP, Kim HB, Kim YK, Park SH, Choi WS#, Choi JY#, Peck KR#, Shin EC#

Immunity. 2021;54(1):44-52.e3

- Selected as “Immunity Best of 2021”

• Association between the neutrophil-to-lymphocyte ratio and obstructive sleep apnea: a meta-analysis

Rha MS, Kim CH, Yoon JH, Cho HJ

Scientific Reports. 2020;10(1):10862

• Human liver CD8+ MAIT cells exert TCR/MR1-independent innate-like cytotoxicity in response to IL-15

Rha MS, Han JW, Kim JH, Koh JY, Park HJ, Kim SI, Kim MS, Lee JG, Lee HW, Lee DH, Kim W, Park JY, Joo DJ#, Park SH#, Shin EC#

Journal of Hepatology. 2020;73(3):640-650

• Superantigen-related TH2 CD4+ T cells in nonasthmatic chronic rhinosinusitis with nasal polyps

Rha MS*, Kim SW*, Chang DY*, Lee JK, Kim J, Park SH, Khalmuratova R, Lim HS, Eun KM, Hong SN, Kim DW#, Shin EC#

Journal of Allergy and Clinical Immunology. 2020;145(5):1378-1388.e10

- Selected as “The Editor’s Choice” in JACI 2020 May

• Sinonasal pleomorphic adenoma: a single institution case series combined with a comprehensive review of literatures

Rha MS, Jeong SW, Cho HJ, Yoon JH, Kim CH

Auris Nasus Larynx. 2019;46(2):223-229 

SCI/SCIE Publication List (Contributing Author)

• Posterior pillar hypertrophy as a novel anatomical predictor of surgical success in obstructive sleep apnea

Jeong Y, Park JJ, Rha MS, Cho HJ

Clinical and Experimental Otolaryngology. 2026;19(1):97-102

• Cell-type specific IL-5Rα distribution and IL-5-Induced CCL11 expression in human nasal epithelium

Kim Y, Kang M, Seo J, Kim S, Rha MS, Kim CH, Cho HJ

Allergy. 2025;80(9):2654-2659

• Dissolving Microneedle for Maintaining the Integrity of HPV Virus-Like Particles Enabling Durable Sterile Protection Across Various Mucosal Tissues

Kim H, Hwang I, Seo J, Kim C, Choi IJ, Kang M, Rha MS, Hong Y, Kim J, Baek SK, Park JH, Cho HJ, Kwak K

Advanced Healthcare Materials. 2025;14(24):e2500963

• Spatiotemporal Regulation by Downstream Genes of Prok2 in the Olfactory System: From Development to Function

Kim BR, Rha MS, Cho HJ, Yoon JH, Kim CH

Frontiers in Cell and Developmental Biology. 2025;13:1550845

• Inflammation-driven periostin in ECRS has contrasting effects on tissue structural integrity and osteitis

Kim SI, Rha MS, Kim JS, Ahn SH, Ryu JH, Cho HJ, Kim CH

Frontiers in Immunology. 2025;16:1596746

• First prospective study on single-port robotic tongue base resection for sleep apnea

Jeong Y, Rha MS, Kim CH, Cho HJ

Head & Neck. 2025; 47(4):1071-1078

• Patients with mild COVID-19 exhibit paradoxically low functional avidity of SARS-CoV-2 membrane protein-reactive CD4+ T cells

Kim AR, Koh JY, Rha MS, Jung JH, Ko JH, Choi HK, Jeon JH, Seok H, Park DW, Peck KR, Choi JY, Park SH, Choi WS, Jeong HW, Shin EC

Immune Network. 2025;25(2):e4

• S100A9 induces tissue remodeling of human nasal epithelium in chronic rhinosinusitis with nasal polyp

Ahn SH, Oh JT, Kim DH, Lee EJ, Rha MS, Cho HJ, Kim CH

International Forum of Allergy & Rhinology. 2025;15(2):135-148

• Differential regulation of viral entry-associated genes modulated by inflammatory cytokines

Noh HE, Rha MS, Jeong Y, Seo JH, Kang M, Moon UY, Kim CH, Cho HJ

Journal of Medical Virology. 2024;96(9):e29913

• Let-7a-5p Inhibits IL-4-induced MUC5AC Expression and Mucus Hypersecretion and Is Transported in Nasal Lavage Extracellular Vesicles

Jeong D, Chung YW, Ji H, Kim J, Seo JH, Han S, Moon S, Rha MS, Cho HJ, Kim CH, Ryu JH, Kim HH, Yoon JH

American Journal of Respiratory Cell and Molecular Biology 2024; 71(3):375-379

• Airway epithelial CD47 plays a critical role in inducing influenza virus-mediated bacterial super-infection

Moon S, Han S, Jang IH, Ryu J, Rha MS, Cho HJ, Yoon SS, Nam KT, Kim CH, Park MS, Seong JK, Lee WJ, Yoon JH, Chung YW, Ryu JH

Nature Communications 2024;15(1):3666

• Visualization of the relationship between electrogustometry and whole mouth test using multidimensional scaling

Ha JG, Kim BR, Cho A, Jeong Y, Rha MS, Kang JW, Cho HJ, Yoon JH, Kim CH

Scientific Reports. 2023;13:8798

• Spatiotemporal dynamics of the development of mouse olfactory system from prenatal to postnatal period

Kim BR, Rha MS, Cho HJ, Yoon JH, Kim CH

Frontiers in Neuroanatomy. 2023;17:1157224

• Calprotectin in chronic rhinosinusitis eosinophil extracellular traps

Ahn SH, Shin KH, Oh JT, Park SC, Rha MS, Kim SI, Cho HJ, Yoon JH, Kim CH

International Forum of Allergy & Rhinology. 2023;13(10):1926-1936

• KIR+CD8+ and NKG2A+CD8+ T cells are distinct innate-like populations in humans

Choi SJ, Koh JY, Rha MS, Seo IH, Lee H, Jeong S, Park SH, Shin EC

Cell Reports. 2023;42(3):112236

• Single-cell RNA sequencing identifies shared differentiation paths of mouse thymic innate T cells

Lee MJ, Lee E, Han SK, Choi YH, Kwon DI, Choi H, Lee K, Park ES, Rha MS, Joo DJ, Shin EC, Kim S, Kim JK, Lee YJ

Nature Communications. 2020;11(1):4367

• Functions of human liver CD69+CD103-CD8+ T cells depend on HIF-2α activity in healthy and pathologic livers

Kim JH, Han JW, Choi YJ, Rha MS, Koh JY, Kim KH, Kim CG, Lee YJ, Kim AR, Park J, Kim HK, Min BS, Seo SI, Kang M, Park HJ, Han DH, Kim SI, Kim MS, Lee JG, Lee DH, Kim W, Park JY, Park SH, Joo DJ, Shin EC

Journal of Hepatology. 2020;72(6):1170-1181'

• Early reduction of regulatory T cells is associated with acute rejection in liver transplantation under tacrolimus-based immunosuppression with basiliximab induction

Han JW, Joo DJ, Kim JH, Rha MS, Koh JY, Park HJ, Lee JG, Kim MS, Kim SI, Shin EC, Park JY, Park SH

American Journal of Transplantation. 2020;20(8):2058-2069

• The effects of alcohol consumption and smoking on allergy risk in Korean adults

Kang JW, Baek SH, Rha MS, Kim JH

American Journal of Rhinology & Allergy. 2014;28(1):e35-e39

• Orbital apex syndrome caused by invasive aspergillosis

Kim JW, Rha MS, Kim JH, Kang JW

Journal of Craniofacial Surgery. 2014;25(2):e191-e193