Nano to Macro Materials for Multidirectional Healthcare Applications

"Be good to others not because they are good to you, but because you are good."

Research Keywords: 

 

Dr. Ranjit De is an innovative researcher who has received foundational training in polymer science, specifically exploring the physicochemical properties of polyelectrolytes in solution phase. However, he has since ventured into the realm of polymeric nanoparticles, light-responsive nanomaterials, etc., and their applications in various fields. His motivation stems from the conviction that revolutionary technologies can arise when different research areas converge.

One of his notable inventions is a versatile nanocarrier capable of loading and delivering sensitive therapeutics with protein-like properties, while also safeguarding them from degradation caused by heat and enzymes. This technology paves the way to negate the requirement of refrigeration otherwise required for the protection of proteinaceous therapeutics, e.g., vaccines, as the nature does. Consequently, it offers a solution to the challenges associated with transporting sensitive therapeutic materials to remote areas of developing countries lacking refrigeration infrastructure. These significant findings were featured on the cover page of a science journal published by the prestigious Royal Society of Chemistry.

In another recent project, Dr. De devised a simple, rapid, cost-effective, and environmentally friendly method to create nitrogen-enriched carbon quantum dots using a readily available microwave oven. These zero-dimensional nanomaterials exhibited excellent solubility in both aqueous and organic environments, making them suitable for a wide range of applications. These include the development of invisible ink, light-emitting polymeric molds, long-lasting stability on cellulose papers, finger imprinting, metal ion detection, pH sensing, ROS sensing, and bioimaging/drug delivery. Moreover, when these fluorescent graphitic carbon dots were tested on human neuroblastoma cells, they demonstrated exceptional cell viability, reaching approximately 100%. The groundbreaking nature of this work was acknowledged by its selection for highlighting on the cover page of a journal published by the Royal Society of Chemistry.

Dr. De also bears expertise in fabricating molecule sensor using the array of nobel metal nanostructures. Employing the surface-enhanced Raman scattering (SERS), the detection of such molecules have been highly successful wven when they were present in extremely low concentrations. 

Dr. De's contributions have not gone unnoticed, as he received the esteemed 'J. K. Mittal' award for delivering the best oral presentation on his doctoral research from the Indian Society for Surface Science and Technology. His work has resulted in the publication of over 30 research papers to date, and researchers worldwide are actively utilizing his technologies.

Furthermore, Dr. De's overarching goal is to seamlessly integrate nanomaterials into biological systems, introducing functionalities that surpass the limitations of biology itself. By achieving this objective, he aims to transcend our biological boundaries and enable novel applications of nanomaterials in diverse biological contexts.

His objective is to be enriched with academic excellences through interdisciplinary research that supports proficiency to compete global challenges beyond the fields of nanotechnology, chemistry, biology, and physics to yield purpose driven discovery for societal benefits. He is inquisitive, fun-loving, and always ready to assist and collaborate. He believes “Interdisciplinary research is the future of science, and the measure of success is its real-life impact”. 

Dr. Ranjit De, PhD

Research Associate Professor

Biomedical Nanomaterials Lab, Department of Materials Science and Engineering, Pohang University of Science and Technology (2023 QS World Univ. Rank 71), Pohang 37673, South Korea.

E-mail: deranjit@postech.ac.kr; deranjit@gmail.com 

Google Scholor Link

Lab Webpage 

Postdoctoral Activities

Research Grants

Grant Received – Total KRW 300,000,000
 

Project Title (Brief): Development of Polymeric Nanocarrier for Therapeutic Delivery Across Blood-Brain Barrier and Bioimaging. 

Role: Principal Investigator (PI) 

Funding Agency: National Research Foundation (NRF), Korea. 

Project Title (Brief): Polyelectrolyte Complex Coacervate  for Protein Delivery and Bioimaging.

Role: Principal Investigator (PI) 

Funding Agency: National Research Foundation (NRF), Korea

Awards

Service to Scientific Community