Selda Abyar, Lujiao Huang, Yurii Husiev, Ludovic Bretin, Bobby Chau, Vadde Ramu, Jaap Wildeman, Kimberley Belfor, Lukas Wijaya, VE van der Noord, Amy C Harms, Maxime A Siegler, Sylvia E Le Dévédec, Sylvestre Bonnet. Oxygen-dependent interactions between the ruthenium cage and the photoreleased inhibitor in NAMPT-targeted photoactivated chemotherapy. DOI:10.26434/chemrxiv-2024-mzftm
Till Neumann, Vadde Ramu, Julie Bertin, Menglan He, Caitlan Vervisch, Michael P. Coogan, and Helene C. Bertrand. Rhenium fac-Tricarbonyl Bisimine Chalcogenide Complexes: Synthesis, Photophysical Studies, and Confocal and Time-Resolved Cell Microscopy. Inorg. Chem. 2024, 63, 2, 1197–1213.
Red-Light Activation of a Microtubule Polymerization Inhibitor via Amide Functionalization of the Ruthenium Photocage. Ludovic Bretin*, Yurii Husiev*, Vadde Ramu*, Liyan Zhang, Matthijs Hakkennes, Selda Abyar, Andrew C Johns, Sylvia Le Dévédec, Tania Betancourt, Alexander Kornienko, Sylvestre Bonnet. Just accepted in 2023, Angew Chemie. Int.Edn. https://doi.org/10.1002/anie.202316425. Hot Article.
Ludovic Bretin, Vadde Ramu, Sipeng Zheng, Sophie Gerhardt, Serge Zander, Alexander Kornienko, Sylvestre Bonnet. Testing ruthenium-based photoactivated chemotherapy on tumor-bearing mice models as a new treatment for uveal melanoma. Photodiagnosis and Photodynamic Therapy, 2023, 41, 103403.
Xue-Quan Zhou, Peiyuan Wang, Vadde Ramu, Suhua Jiang, Xuezhao Li, Selda Abyar, Panagiota Papadopoulou, Yang Shao, Maxime Siegler, Francesco Buda, Alexander Kros, Wen Sun, Sylvestre Bonnet. In vivo metallophilic self-assembly of a light-activated anticancer drug. Nature Chemistry, 2023,15, 980–987.
Quanchi Chen, Jordi-Amat Cuello-Garibo, Ludovic Bretin, Liyan Zhang, Vadde Ramu, Yasmin Aydar, Yevhen Batsuin, Sharon Bronkhorst, Yurii Husiev, Nataliia Beztsinna, Lanpeng Chen, Xue-Quan Zhou, Claudia Schmidt, Ingo Ott, Martine J. Jager, Albert M. Brouwer, B. Ewa Snaar-Jagalska, Sylvestre Bonnet. Photosubstitution in a trisheteroleptic ruthenium complex inhibits conjunctival melanoma growth in a zebrafish orthotopic xenograft model. Chemical Science, 2022 13, 6899. (IF 9.82)
Junda Zhang, Vadde Ramu, Xue-Quan Zhou, Carolina Frias, Daniel Ruiz-Molina, Sylvestre Bonnet, Claudio Roscini, Fernando Novio. Photoactivable Ruthenium-Based Coordination Polymer Nanoparticles for Light-Induced Chemotherapy. Nanomaterials, 2021, 11, 3089. (IF 5.71)
Zhou, Xue-Quan; Carbó-Bagué, Imma; Siegler, Maxime; Hilgendorf, Jonathan; Basu, Uttara; Ott, Ingo; Liu, Rongfang; Zhang, Liyan; Vadde Ramu, IJzerman, Adriaan; Bonnet, Sylvestre. Rollover cyclometalation vs. nitrogen coordination in tetrapyridyl anticancer gold (III) complexes: effect on protein interaction and toxicity. J. Am. Chem. Soc. Au, 2021, 4, 380-395. (IF not known yet)
Quanchi Chen, Vadde Ramu, Yasmin Aydar, Arwin Groenewoud, Xuequan Zhou, Martine J Jager, Houston Cole, Colin G. Cameron, Sherri A. McFarland, Sylvestre Bonnet, B. Ewa Snaar-Jagalska. TLD1433 photosensitizer inhibits conjunctival melanoma cells in zebrafish ectopic and orthotopic tumour models. Cancers, 2020, 12 (587), 1-23. (IF 6.63)
Xue-Quan Zhou, Ming Xiao, Vadde Ramu Jonathan Hilgendorf, Xuezhao Li, Panagiota Papadopoulou, Maxime A. Siegler, Alexander Kros, Wen Sun, and Sylvestre Bonnet, The self-assembly of a cyclometalated palladium photosensitizer into proteins-stabilized nanorods triggered drug uptake in vitro and in vivo. J. Am. Chem. Soc, 2020, 142, 23, 10383-10399. (IF 15.4)
Vincent HS van Rixel, Vadde Ramu, Austin Bo Auyeung, Nataliia Beztsinna, David Y Léger, Stan T Hilt, Sylvia E Le Dévédec, Tugba Yildiz, Tania Betancourt, Brenton Gildner, Todd W. Hudnall, Vincent Sol, Bertrand Liagre, Alexander Kornienko, and Sylvestre, Bonnet Photo-uncaging of a ruthenium-caged microtubule-targeted rigidin analogue in hypoxic cancer cells and in a xenograft mouse model. J. Am. Chem. Soc, 2019, 141, 46, 18444-18454 (IF 15.4)
Vadde Ramu, Gandra Upendar Reddy, Jingjing Liu, Patrick Hoffmann, Rudrakant Sollapur, Ralf Wyrwa, Stephan Kupfer, Christian Spielmann, Sylvestre Bonnet, Ute Neugebauer, Alexander Schiller. Two‐Photon‐Induced CO‐Releasing Molecules as Molecular Logic Systems in Solution, Polymers, and Cells. Chemistry- A European Journal, 2019, 25, 8453. (hot article, cover page).(IF 5.23)
Vadde Ramu, Sunil Aute, Nandaraj Taye, Rweetuparna Guha, Michael G. Walker, Devaraj Mogare, Apoorva Parulekar, Jim A. Thomas, Samit Chattopadhyay and Amitava Das. Photo-Induced Cytotoxicity, Anti-Metastatic behaviour of Ruthenium (II)-Polypyridyl Complexes conjugated with tyrosine and tryptophan. Dalton Transactions, 2017, 46 (20), 6634-6644. (IF 4.56)
Michael G. Walker, Vadde Ramu, Anthony. J. H. M. Meijer, Amitava Das, and Jim A Thomas. A ratiometric sensor for DNA based on a dual emission Ru (dppz) light switch complex. Dalton Transactions, 2017, 46 (18), 6079-6086. (IF 4.56)
Vadde Ramu, Firoj Ali, Nandaraj Taye, Bikash Garai, Aftab Alam and Samit Chattopadhyay, and Amitava Das, New Imaging Reagents for Lipid Dense Region in Live cells and Nucleus in Fixed MCF- 7 cells. Journal of Material Chemistry B, 2015, 3, 7177-7185. (hot article) (IF 6.33)
Vadde Ramu, Martin R. Gill, Paul J. Jarman, David Turton, Jim A. Thomas, Amitava Das and Carl Smythe, Cytostatic Ruthenium (II)-Platinum (II) Bis(terpyridyl) Anticancer Complex That Blocks Entry into S Phase by Up- regulating p27KIP1. Chemistry- A European Journal, 2015, 21, 9185-9197. (IF 5.23)
Suman Pal, Vadde Ramu, Nandaraj Taye, Srinivasa Reddy, Samit Chattopadhyay, and Amitava Das. GSH Induced Controlled Release of Levofloxacin from a Purpose-Built Prodrug: Luminescence Response for Probing the Drug Release in Escherichia coli and Staphylococcus aureus. Bioconjugate chemistry, 2016, 27 (9), 2062-2070. (IF 4.77)
Upendar Reddy G, Vadde Ramu, Sovan Roy, Nandaraj Taye, Samit Chattopadhyay, Amitava Das. A specific probe for Hg2+ to delineate even H+ in pure aqueous buffer/Hct116 colon cancer cells: HgII- ƞ2- arene -interaction and a TBET-based fluorescence response. Chemical Communication, 2014, 50, 14421-14424. (IF 6.22)
Priyadip Das, Amrita Ghosh, Manoj K. Kesharwani, Vadde Ramu, Biswajit Ganguly, and Amitava Das. ZnII -2, 2’: 6, 2’’-Terpyridine-based complex as fluorescent chemosensor for PPi, AMP & ADP. European Journal of Inorganic Chemistry, 2011, 3050–3058. (IF 2.52)