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Postdoctoral Research Associate

Integrative Musculoskeletal Biomechanics Research Group

Insigneo Institute, University of Sheffield, UK

Incoming Assistant Professor (Musculoskeletal Biomechanics), National Institute of Technology Agartala

About me

I am Rajdeep Ghosh, a Postdoctoral Research Associate at the Integrative Musculo-Skeletal Biomechanics (IMSB) Research Group, Insigneo Institute, at The University of Sheffield, UK, and is working with Prof. Damien Lacroix and Prof. Enrico Dall'Ara. My current research focuses on these key areas: (1) Developed a validation framework of subject-specific homogenised finite element model of metastatic vertebra from DVC experiments, (2) Developed a CT2FE pipeline to estimate fracture risk of metastatic vertebra, (3) Developed a single-blinded image anonymisation protocol through the use of virtual sandbox environment for metastatic spine CT images, (4) Working on the development of spine segments from qCT and MRI images.

In addition, I have also worked on (4) the influence of different segmentation protocols in estimating vertebral fracture risk, (5) Understanding the influence of lesion size and location on vertebral strength.

Before that, I was a Project Scientist B (September 2022 - October 2023) and Senior Project Scientist (August 2022 - September 2022) at Indian Institute of Technology Delhi working with Dr. Kaushik Mukherjee and Prof. Anoop Chawla. At IIT Delhi, my research centered around four key areas: (1) Developing a stress-based material homogenization framework to find the effective material properties of additively manufactured lattice structures, (2) Biomechanical evaluation of stock temporomandibular joint (TMJ) implants with variable bone-implant interface conditions under quasi-static physiological musculo-skeletal loading, (3) A retrospective study to understand the influence of TMJ ankylosis on morphometry of human mandibles in Indian subjects based on a CT-based reconstructed mandibles, and (4) Understand the influence of bone material homogenization and edentulous mandible on biomechanical assessment of TMJ implants.

I hold a Ph.D. in Bone Biomechanics and Implant Design from the Department of Mechanical Engineering at the Indian Institute of Technology Guwahati under the supervision of Prof. Debabrata Chakraborty and Dr. Souptick Chanda. My doctoral research centered on: (1) understanding the influence of macro-textured implant topographies on peri-prosthetic osseointegration, (2) understanding the influence of directional displacements on the osseointegration around textured implants, (3) design optimization of implant topographies based on combined FE-ANN-GA approach, and (4) application of the above philosophy in pre-clinical testing of hip implants with and with textures in a robust musculo-skeletal bone-implant construct under quasi-static physiological loading conditions.

Before my Ph.D., I completed a bachelor's degree in Mechanical Engineering at the National Institute of Technology Agartala. My bachelor's thesis was centered around understanding the fluid flow characterization in PVC pipe with ribbed baffles under the supervision of Dr. Dipak Sen.

My research interests are musculoskeletal biomechanics, computational mechanobiology, medical imaging, implant design, fracture healing, and design optimization.

Science is very close to my heart. My dream is to foster the beauty and mileage of science in most enjoyable way it is possible to as many people.