PUBLICATIONS, PATENTS, PROCEEDINGS & KEY ONLINE PRESENTATIONS

  1. Raja, K. S.*, Ahmed, Z., Mancuso, A., Kalluraya, K. Viso, C., Killen, S. “Hemostatic and Wound Healing Turmeric-Polymer Composite Materials”. U.S. patent application serial numbers 17/938,727 filing date Sep 7 2022. (this invention of a Bleed extinguisherTM to produce Golden GauzeTM nanocomposite is the first bio-resorbable formulation to date which can arrest hemorrhage on the spot that is suitable for long term comprehensive wound care. This addresses an urgent unmet need which the world is facing to treat gunshot and other injuries in a world where the pandemic and war is causing severe delays in reaching victims to medical facilities).

  2. Book Chapter in Polymer based functional materials for biomedical applications (IGI Global, 2021, ISBN1799871983, 9781799871989) Chapter title “Polymeric hybrids to explore biomorph templated evolution of life and for tissue engineering applications.” Raja, K.S.*, Kalluraya, K, Shafik, E. Viso, C., Domingo, E. (Proposes a new biomorph templated theory for the evolution of early animal life forms)

  3. Punia, K., Bucaro, M., Pevtsov, Y., Viso, C., Zubrich, N., Volkova, V., Bykov, A., Kalluraya, K., Shukurova, S., L’Amoreaux, W., & Raja, K. S.* (2020). Chemobrionic Sponge-Mimetic Tubules for Probing the Template-Assisted Evolution of Ocean Sponges and Bioengineering Applications. ACS Earth and Space Chemistry, 4(12), 2289–2298. https://doi.org/10.1021/acsearthspacechem.0c00207 (Cover page article proposes for the first time in literature a new theory of biomorph assisted origin of early animal life forms)

  4. Punia, K., Punia, A., Chatterjee, K., Mukherjee, S., Fata, J., Banerjee, P., Raja, K.S, & Yang, N. L. (2017). Rapid bactericidal activity of an amphiphilic polyacrylate terpolymer system comprised of same-centered comonomers with 2-carbon and 6-carbon spacer arms and an uncharged repeat unit. RSC Advances, 7(17), 10192–10199. https://doi.org/10.1039/c7ra00047b (Selected for Editor’s collection)

  5. Raja, K.S.*.; Shi, W.; Dolai, S.; Averick, S.; L`Amoreaux, W.; Banerjee, P. “Living Copolymer-Protein/Peptide Hybrids For Biomedical Applications” United States Patent US9242010 B2, 2016 (Awarded – this invention amplifies the number of bioactive molecules that can be targeted per protein attaching several copies of multifunctional synthetic polymers to a protein via a biorthogonal chemistry)

  6. Banerjee, P and Raja, K.S.; Curcumin-antibody conjugates as anti-cancer agents United States Patent 9446145, 2016 (Awarded Targets brain tumors with curcumin products)

  7. Punia, K., Bucaro, M., Mancuso, A., Cuttitta, C., Marsillo, A., Bykov, A., L’Amoreaux, W., & Raja, K. S.* (2016). Rediscovering Chemical Gardens: Self-Assembling Cytocompatible Protein-Intercalated Silicate–Phosphate Sponge-Mimetic Tubules. Langmuir, 32(34), 8748–8758. https://doi.org/10.1021/acs.langmuir.6b01721 (Cover Page Article- first article that defines an SMT and demonstrates that hybrid chemical gardens may be used for marine and mammalian cell culture.)

  8. “Averick, A., Dolai, S., Punia, A., Punia, K., Guariglia, S. R., L’Amoreaux, W., Hong, K. L., & Raja, K.S* (2016). Green anchors: Chelating properties of ATRP-click curcumin-polymer conjugates. Reactive and Functional Polymers, 102, 47–52. https://doi.org/10.1016/j.reactfunctpolym.2016.03.009

  9. Mukherjee, S., Baidoo, J., Fried, A., Atwi, D., Dolai, S., Boockvar, J., Symons, M., Ruggieri, R., Raja, K.S, & Banerjee, P. (2016). Curcumin changes the polarity of tumor-associated microglia and eliminates glioblastoma. International Journal of Cancer, 139(12), 2838–2849. https://doi.org/10.1002/ijc.30398

  10. Saltos, J. A., Shi, W., Mancuso, A., Sun, C., Park, T., Averick, N., Punia, K., Fata, J., & Raja, K.S* (2014). Curcumin-derived green plasticizers for poly(vinyl) chloride. RSC Adv., 4(97), 54725–54728. https://doi.org/10.1039/c4ra10581h (development of a completely green plasticizer that could replace phthalates).

  11. Sun, C.; Punia, K.; Mancuso, A.; Dolaib, S.; Fata , J. E.; Castellanos, M.R.; Raja, K. S.* Synthesis, Characterization and Anti-Cervical Cancer Cell Properties of Bovine Serum Albumen Curcumin Conjugate Biochemical and Biophysical Journal of Neutron Therapy & Cancer Treatments (2014), Vol 2 No1 March 2014 ISSN 2331-8368 (Print) 2331-8376

  12. “Langone, P., Debata, P.R., Inigo, J.D.R., Dolai, S., Mukherjee, S., Halat, P., Mastroianni, K., Curcio, G.M., Castellanos, M.R., Raja, K.S and Banerjee, P. (2014), Coupling to a glioblastoma-directed antibody potentiates antitumor activity of curcumin. Int. J. Cancer, 135: 710-719. 10.2174/18715206113139990102

  13. “Raja, K.S *(2013). Editorial (Thematic Issue: Green Anti-Cancer Agents and Ayur Biotechnology: A smart approach towards improving R&D productivity.). Anti-Cancer Agents in Medicinal Chemistry, 13(10), 1467–1468. https://doi.org/10.2174/18715206113139990102 (Defines a drug discovery approach that can systematically load the dice in favor of success in the drug development endeavor to survive the crucial clinical trial stage and secure FDA approval)

  14. Sun, C., Nirmalananda, S., Jenkins, C., Debnath, S., Balambika, R., Fata, J., & Raja, K.S* (2013). First Ayurvedic Approach Towards Green Drugs: Anti Cervical Cancer-Cell Properties of Clerodendrum viscosum Root Extract. Anti-Cancer Agents in Medicinal Chemistry, 13(10), 1469–1476. https://doi.org/10.2174/18715206113139990138

  15. Debnath, S., Saloum, D., Dolai, S., Sun, C., Averick, S., Raja, K.,S & Fata, J. (2013). Dendrimer-Curcumin Conjugate: A Water Soluble and Effective Cytotoxic Agent Against Breast Cancer Cell Lines. Anti-Cancer Agents in Medicinal Chemistry, 13(10), 1531–1539. https://doi.org/10.2174/18715206113139990139

  16. Raja, K.S.*; Banerjee, P.; Lamoreaux, W.; Shi, W.; Auerbach, A.; Novel Curcumin and Tetrahydrocurcumin derivatives” US patent Number 8487139 (2013) awarded- this invention describes new synthetic methodologies towards monofunctional curcumin derivatives.

  17. Langone, P., Debata, P. R., Dolai, S., Curcio, G. M., Inigo, J. D. R., Raja, K.S, & Banerjee, P. (2012). Coupling to a cancer cell-specific antibody potentiates tumoricidal properties of curcumin. International Journal of Cancer, 131(4), E569–E578. https://doi.org/10.1002/ijc.26479

  18. Dolai, S., Shi, W., Corbo, C., Sun, C., Averick, S., Obeysekera, D., Farid, M., Alonso, A., Banerjee, P., & Raja, K.S* (2011). “Clicked” Sugar–Curcumin Conjugate: Modulator of Amyloid-β and Tau Peptide Aggregation at Ultralow Concentrations. ACS Chemical Neuroscience, 2(12), 694–699. https://doi.org/10.1021/cn200088r

  19. Dolai, S., Shi, W., Mondal, B., & Raja, K.S* (2011). Synthesis of Drug/Dye-Incorporated Polymer–Protein Hybrids. Methods in Molecular Biology, 29–42. https://doi.org/10.1007/978-1-61779-151-2_3

  20. Huang, L., Dolai, S., Raja, K.S, & Kruk, M. (2009). “Click” Grafting of High Loading of Polymers and Monosaccharides on Surface of Ordered Mesoporous Silica. Langmuir, 26(4), 2688–2693. https://doi.org/10.1021/la9026943

  21. Raja, K.S*, Balambika, R., Dolai, S., & Shi, W. (2009). The Concept of a Green Drug, Curcumin and It ’ s Derivatives as a Model System. Mini-Reviews in Organic Chemistry, 6(2), 152–158. https://doi.org/10.2174/157019309788167684

  22. Shi, W., Dolai, S., Averick, S., Fernando, S. S., Saltos, J. A., L’Amoreaux, W., Banerjee, P., & Raja, K.S* (2009). A General Methodology Toward Drug/Dye Incorporated Living Copolymer−Protein Hybrids: (NIRF Dye-Glucose) Copolymer−Avidin/BSA Conjugates as Prototypes. Bioconjugate Chemistry, 20(8), 1595–1601. https://doi.org/10.1021/bc900142y

  23. Shi, W., Dolai, S., Rizk, S., Hussain, A., Tariq, H., Averick, S., L’Amoreaux, W., El Idrissi, A., Banerjee, P., & Raja, K.S* (2007). Synthesis of Monofunctional Curcumin Derivatives, Clicked Curcumin Dimer, and a PAMAM Dendrimer Curcumin Conjugate for Therapeutic Applications. Organic Letters, 9(26), 5461–5464. https://doi.org/10.1021/ol702370m ( First report of a high molecular weight dendritic polyphenol conjugate in literature).

  24. Raja, K.S*, McDonald, R., Tuck, S., Rodriguez, R., Milley, B., & Traquina, P. (2007). One-Pot Synthesis, Purification, and Formulation of Bionanoparticle−CpG Oligodeoxynucleotide Hepatitis B Surface Antigen Conjugate Vaccine via Tangential Flow Filtration. Bioconjugate Chemistry, 18(2), 285–288. https://doi.org/10.1021/bc060118q (reports a new method to synthesize and purify nanoparticle vaccine candidates in a single step).

  25. Raja, K. S., Gupta, S. S., Kaltgrad, E., Strable, E., & Finn, M. G. (2005). Virus–glycopolymer conjugates by copper(i) catalysis of atom transfer radical polymerization and azide–alkyne cycloaddition. Chemical Communications, 34, 4315. https://doi.org/10.1039/b502444g (First report of a biononoparticle- polymer conjugate using click chemistry)

  26. Raja, K. S., Wang, Q., & Finn, M. G. (2003). Icosahedral Virus Particles as Polyvalent Carbohydrate Display Platforms. ChemBioChem, 4(12), 1348–1351. https://doi.org/10.1002/cbic.200300759 (First carbohydrate bionanoparticle conjugate in literature)

  27. Raja, K.S.; Wang, Q.; Johnson, John E.; and. Finn, M.G. Hybrid Virus-Polymer Materials. Synthesis and Properties of PEG-Decorated Cowpea Mosaic Virus” Biomacromolecules, 2003, 4(3), 472-476 https://doi.org/10.1021/bm025740+ (First plant virus polymer conjugate in literature)

  28. Wang, Q., Raja, K. S., Janda, K. D., Lin, T., & Finn, M. G. (2002). Blue Fluorescent Antibodies as Reporters of Steric Accessibility in Virus Conjugates. Bioconjugate Chemistry, 14(1), 38–43. https://doi.org/10.1021/bc025587g

  29. Zhang, K., Raja, K. S., & Sun, L. (2003). Looking into the high efficiency of chiral separations using a chiral-polymer as pseudo stationary phase for micellar electrokinetic chromatography. Analytica Chimica Acta, 496(1–2), 185–193. https://doi.org/10.1016/s0003-2670(03)00999-1

  30. Raja, K. S., Raghunathan, V. A., & Ramakrishnan, S. (1998). Synthesis and Properties of Main Chain Discotic Liquid Crystalline Polyethers Based on Rufigallol. Macromolecules, 31(12), 3807–3814. https://doi.org/10.1021/ma9716342

  31. Raja, K. S., Ramakrishnan, S., & Raghunathan, V. A. (1997). Asymmetric Discotic Liquid Crystals Based on Rufigallol. Chemistry of Materials, 9(7), 1630–1637.

  32. Raja K.S.*; L`Amoreaux, W.; Bucaro, M.; Naider, F.; Kruk, M.; Punia, K. ∞Synthesis and characterization of cytocompatible chemical garden biomaterials”, 2019, US patent application number US 62/797,643.

  33. Raja, K.S*; Fata, J.E., Sun, C., Balambika, R. Bolton.D.; Clerodendrum viscosum and methods of use” 2018 US patent US10059924B2 (Awarded).

  34. Raja, K.S*; Alonso, A. ; Banerjee, P.; Dolai, S.; Averick, S.; Corbo, C.; Shi, W.; Debnath, S. ∞; Mogha, S “Curcumin derivatives” 2017 US Patent number 9650404 (Awarded, this is an invention of “Clicked” carbohydrate curcumin conjugates with amplified bioactivity against amyloid plaque to address Alzheimer’s disease).

  35. Einbond, L.S. ; and Raja, K.S. “Triterpene glycoside and triterpene compositions and methods of using same” United States Patent 9643995 2017 (Awarded)

  36. Novel Curcumin and Tetrahydocurcumin derivatives.” Raja, K.S.*; Banerjee, P.; Lamoreaux, W.; Shi, W.; Auerbach, A.; Canadian Patent Number CA2665916, 2015 (Awarded).

  37. Raman A; Satheesh Kumar; Manjunatha N; Natesh, G.K.; Raja, K.S.; and Rema Balambika. "A Substance Delivery Device" PCT., W00100105, 2001.

  38. Raman, A.; Raja, K.S.; Balambika, R.; Natesh, G.K., Satheesh Kumar and Manjunatha.S “A Substance Delivery Device” Indonesian Patent, W-00200102883, 2001.

  39. Raman, A.; Raja, K.S.; Balambika, R.; and Natesh, G.K. “An Insect Repellant Device” U.K. Patent, 9915085.6, 1999.

  40. Raman, A.; Raja, K.S.; Balambika, R.; and Natesh, G.K. “A Substance Delivery Device” Taiwan Patent, 88111477, 1999

  41. Raja, K.S.*, Dolai, S.; Shi, W.; Wang, Q. “Bionanoparticles as nanoscaffolds for chemical manipulation”. Encyclopedia of Nanoscience and Nanotechnology, Marcel Dekker, 2009, Second Edition.

  42. Raja, K.S * Sponge Mimetic Tubules (SMT) to explore biomorph templated evolution of animal life. Innovations in Chemical Biology”, American Chemical Society, MARM meeting, June 2021 Abstract ID: 3569347

  43. Mancuso, A.; Pillarella, N.; Sadek, A.; Raja, K.* Polyelectrolytes, Potent Excipients for Protein Drugs. American Chemical Society National Meeting, Boston, MA, August 2018. Poster number MEDI 246

  44. Mancuso, A.; Pillarella, N.; Sadek, A.; Raja, K.S.* Incorporation of Therapeutic Proteins into Polyester Nanofibers via Protein-Polyelectrolyte Complexes. American Chemical Society National Meeting, New Orleans, LA. March 2018. Poster number MEDI 400.

  45. Mancuso A., Pillarella N., Raja K.*. Polyester Films/Implants Loaded with Insulin-Polyelectrolyte Particles for the Treatment of Diabetes. American Chemical Society National Meeting, New Orleans, LA. March 2018 Poster number MEDI 401.

  46. Mancuso, A.; Chatterjee, K.; Punia, P.; Raja, K.* Curcumin Loaded PLGA Nanofibers for the Treatment of Cancer, Microbial Infections, and the Promotion of Wound Healing. American Chemical Society National Meeting, Washington DC. August 2017 Poster number PMSE 402.

  47. Punia, K.; Averick, A.; Punia, A.; Dolai, S.; Guariglia, S.; L'Amoreaux, W.; Raja, K.* Curcumin-glucose macromolecular conjugates via click-chemistry for selective chelation of toxic metals ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253 2017

  48. Punia, K.; Raja, K.* Sponge mimetic tubules: Programmable stigmergy scaffolds for 3D marine, mammalian cell culture and bioelectronic. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY National Meeting & Exposition April 2017 (PAPER ID: 2658708) (only paper from CUNY selected for Sci-Mix session)

  49. Punia, A; Punia, K.; Chatterjee, K.; Mukherjee, S.; Fata, J.; Banerjee, P.; Raja, K.; Yang* ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253 2017 Bactericidal and non-hemolytic macromolecules through synergistic variation in spacer arm and separate center design.

  50. Punia, K.; Sun, C.; Dolai, S.; Mancuso, A.; Fata, J.E.; Castellanos, M.; and Raja, K.S.* Synthesis and properties of curcumin conjugates as green cancer drug delivery system.” abstracts of papers, 252th ACS National Meeting & Exposition, Philadelphia, United States, August 21-25, 2016.

  51. Programmable Sponge Biomimics for 3D Marine Cell Culture and Material Science Applications.” Raja, K.S.*; Punia, K.; Manchanda, A. S.; Bucaro, M.; Proceedings of the International Conference On Materials For the Millenium (MATCON) 2016, 1, 35.

  52. Mancuso, A.; Chatterjee, K.; Punia, P.; Rajendra, V.; Liang, X.Q.; Fata, J.; Castellanos, M.; Raja, K.* Delivering Phytochemical Therapeutics Through Polymer Nanofibers. American Chemical Society National Meeting, Philadelphia, Pa. August 21, 2016 Poster number: MEDI193.

  53. Punia, K.; Bucaro, M.; Mancuso, A.; Cuttitta, C.; Marsillo, A.; L'amoreaux, W.; Raja, K.* Programmable inorganic scaffolds based on sponge biomimicry for 3D marine, mammalian cell culture and bioelectronics. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252 2016

  54. Punia, K.; Sun. C; Dolai, S.; Mancuso, A.; Fata, J.; Raja, K.* Synthesis and properties of curcumin conjugates as a green cancer drug delivery system. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252 2016

  55. Punia, K.; Bucaro, M.; Mancuso, A.; Cuttitta, C.; Marsillo, A.; Bykov, A.; L’Amoreaux, W.; Raja, K.S.* Programmable inorganic scaffolds based on sponge biomimicry for 3D Marine, Mammalian Cell Culture and Bioelectronics.” abstracts of papers, 252th ACS National Meeting & Exposition, Philadelphia, United States, August 21-25, 2016.

  56. Punia, K, Chatterjee, K, Mancuso, M, Rajendra, V, Castellanos, M, Fata, J, Raja, K.S.* Nutraceuticals loaded poly (lactic-co-glycolic acid) nanofibres by solution blow spinning for the treatment of cervical cancer ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250 2015

  57. Saltos, J.; and Raja, K.S.* Synthesis of eco-friendly plasticizers using curcumin di-esters. 239th ACS National Meeting, San Francisco, CA, United States, March 21-25, 2010, CHED-718 (this poster won a certificate of merit from the ACS green chemistry section)


A Happiness Toolkit as part of Toolkit for Success & Balance in Life modules proposed to assist students cope with the stress and other challenges:

https://drive.google.com/file/d/1XE-gQ8X1K-z9ifmEoO9db4fdqrZqd37H/view