Publications
See Google Scholar for latest publications
Kolo AO, Raghavan R. 2023. Impact of endosymbionts on tick physiology and fitness. Parasitology. DOI: 10.1017/S0031182023000793.
Sachan M, Brann KR, Fullerton MS, Voth DE, Raghavan R. 2023. MicroRNAs contribute to host response to Coxiella burnetii. Infect Immun. e0019922. doi: 10.1128/iai.00199-22.
Krieger MC, Merritt J, Raghavan R. 2022. Genome-wide identification of novel sRNAs in Streptococcus mutans. J Bacteriol. 204:e0057721. doi: 10.1128/jb.00577-21.
Krieger MC, Dutcher HA, Ashford AJ, Raghavan R. 2022. A peroxide-responding sRNA evolved from a peroxidase mRNA. Mol Biol Evol. https://doi.org/10.1093/molbev/msac020.
Wright AP, Dutcher HA, Butler B, Nice TJ, Raghavan R. 2021. A small RNA is functional in Escherichia fergusonii despite containing a large insertion. Microbiology. doi: 10.1099/mic.0.001099.
Brenner AE, Raghavan R. 2021. Complete mitochondrial genome sequence of the Gulf Coast tick Amblyomma maculatum. Microbiol Resour Announc. 10: e00431-21. https://doi.org/10.1128/MRA.00431-21.
Brenner AE, Munoz-Leal S, Sachan M, Labruna MB, Raghavan R. 2021. Coxiella burnetii and related tick endosymbionts evolved from pathogenic ancestors. Genome Biol Evol. https://doi.org/10.1093/gbe/evab108.
Millar JA, Raghavan R. 2021. Modulation of bacterial fitness and virulence through antisense RNAs. Front. Cell. Infect. Microbiol. 10:596277. doi: 10.3389/fcimb.2020.596277.
JF Hebert, JA Millar, R Raghavan, A Romney, JE Podrabsky, MY Rennie et al. 2021. Male fetal sex affects uteroplacental angiogenesis in growth restriction mouse model. Biol Reprod. doi: 10.1093/biolre/ioab006.
Wachter S, Hicks LD, Raghavan R, Minnick MF. 2020. Novel small RNAs expressed by Bartonella bacilliformis under multiple conditions reveal potential mechanisms for persistence in the sand fly vector and human host. PLoS Negl Trop Dis 14(11): e0008671. https://doi.org/10.1371/journal.pntd.0008671
Wachter S, Bonazzi M, Shifflett K, Moses AS, Raghavan R, Minnick MF. 2019. A CsrA-binding, trans-acting sRNA of Coxiella burnetii is necessary for optimal intracellular growth and vacuole formation during early infection of host cells. J Bacteriol. 201: pii: e00524-19. doi: 10.1128/JB.00524-19.
Zou Z, Raz A, Qin H, Brenner AE, Raghavan R, Millar JA, Gu Q, Xie Z, Kreth J, Merritt J. 2018. LytTR regulatory systems: a potential new class of prokaryotic sensory system. PLoS Genet. 14: e1007709. doi: 10.1371/journal.pgen.1007709.
Chen Z, Raghavan R, Qi F, Merritt J, Kreth J. 2018. Genome-wide screening of potential RNase Y-processed mRNAs in the M49 serotype Streptococcus pyogenes NZ131. MicrobiologyOpen. e671. doi: 10.1002/mbo3.671.
Wachter S, Raghavan R, Wachter J, Minnick MF. 2018. Identification of novel MITEs (miniature inverted-repeat transposable elements) in Coxiella burnetii: implications for protein and small RNA evolution. BMC Genomics. 19:247. doi: 10.1186/s12864-018-4608-y.
Gerhart JG, Dutcher HA, Brenner AE, Moses AS, Grubhoffer L, Raghavan R. 2018. Multiple acquisitions of pathogen-derived Francisella endosymbionts in soft ticks. Genome Biol Evol. doi:10.1093/gbe/evy021.
Dutcher HA, Raghavan R. 2018. Origin, evolution, and loss of bacterial small RNAs. Microbiol Spectr. doi: 10.1128/microbiolspec.RWR-0004-2017.
Moses AS, Millar JA, Bonazzi M, Beare PA, Raghavan R. 2017. Horizontally acquired biosynthesis genes boost Coxiella burnetii’s physiology. Front Cell Infect Microbiol 7:174. doi: 10.3389/fcimb.2017.00174.
Millar JA, Beare PA, Moses AS, Martens CA, Heinzen RA, Raghavan R. 2017. Whole-genome sequence of Coxiella burnetii Nine Mile RSA439 (Phase II, Clone 4): the laboratory workhorse strain. Genome Announc. doi: 10.1128/genomeA.00471-17.
Kacharia FR, Millar JA, Raghavan R. 2017. Emergence of new sRNAs in enteric bacteria is associated with low expression and rapid evolution. J Mol Evol 84:204-213. doi: 10.1007/s00239-017-9793-9.
Millar JA, Raghavan R. 2017. Accumulation and expression of multiple antibiotic resistance genes in Arcobacter cryaerophilus that thrives in sewage. PeerJ 5:e3269. doi: 10.7717/peerj.3269.
Hebert JF, Millar JA, Romney A, Raghavan R, Podrabsky J, Morgan TK. 2017. Placental gene expression is affected by male fetal sex and maternal genotype in fetal growth restriction model. Reprod Sci 24, 212A.
Gerhart JG, Moses AS, Raghavan R. 2016. A Francisella-like endosymbiont in the Gulf Coast tick evolved from a mammalian pathogen. Sci Rep 6: 33670. doi: 10.1038/srep33670.
Warrier I, Walter MC, Frangoulidis D, Raghavan R, Hicks LD, Minnick MF. 2016. The intervening sequence of Coxiella burnetii: characterization and evolution. Front Cell Infect Microbiol 6:83. doi: 10.3389/fcimb.2016.00083.
Kreth J, Giacaman RA, Raghavan R, Merritt J. 2016. The Road Less Traveled – Defining molecular commensalism with Streptococcus sanguinis. Mol Oral Microbiol 32:181-196. doi: 10.1111/omi.12170.
Raghavan R. 2016. A repeat motif on a Coxiella effector protein facilitates apoptosis inhibition. Virulence 7:369-371. doi: 10.1080/21505594.2016.1156834.
Millar JA, Valdes R, Kacharia FR, Landfear SM, Cambronne ED, Raghavan R. 2015. Coxiella burnetii and Leishmania mexicana residing within similar parasitophorous vacuoles elicit disparate host responses. Front Microbiol 6:794. doi: 10.3389/fmicb.2015.00794.
Smith TA, Driscoll T, Gillespie JJ, Raghavan R. 2015. A Coxiella-like Endosymbiont is a potential vitamin source for the Lone Star Tick. Genome Biol Evol 7:831-838. doi:10.1093/gbe/evv016.
Raghavan R, Kacharia FR, Millar JA, Sislak CD, Ochman H. 2015. Genome rearrangements can make and break small RNA genes. Genome Biol Evol 7: 557-566. doi:10.1093/gbe/evv009.
Lybecker M, Bilusic I, Raghavan R. 2014. Pervasive transcription: detecting functional RNAs in bacteria. Transcription 5: e944039. doi: 10.4161/21541272.2014.944039.
Warrier I, Hicks LD, Battisti JM, Raghavan R, Minnick MF. 2014. Identification of Novel small RNAs and characterization of the 6S RNA of Coxiella burnetii. PLoS ONE 9: e100147. doi: 10.1371/journal.pone.0100147.
Raghavan R, Kelkar YD, Ochman H. 2012. A selective force favoring increased G+C contend in bacterial genes. Proceedings of the National Academy of Sciences USA 109:14504-14507.
Raghavan R, Sloan DB, Ochman H. 2012. Antisense transcription is pervasive but rarely conserved in enteric bacteria. mBio 3:e00156-12.
Minnick MF, Raghavan R. 2012. Developmental biology of Coxiella burnetii. Adv Exp Med Biol. 984:231-248.
Raghavan R, Groisman EA, Ochman H. 2011. Genome-wide detection of novel regulatory RNAs in E. coli. Genome Res 21: 1487-1497.
Raghavan R, Sage A, Ochman H. 2011. Genome-wide detection of transcription start sites yield a novel thermo-sensing RNA and new CRP-regulated genes in E. coli. J Bacteriol 193:2871-2874.
Minnick MF and Raghavan R. 2011. Genetics of Coxiella burnetii: on the path of specialization. Future Microbiol 6: 1297-1314.
Hicks LD, Warrier I, Raghavan R, Minnick MF. 2011.Ribozyme stability, exon skipping and potential role for RNA helicase in Coxiella burnetii intron splicing. J Bacteriol 193: 5292-5299.
Kuo C-H, Ochman H and Raghavan R. 2011. The genomics of Escherichia coli and beyond. In Walk, S.T. and P.C.H. Feng (ed.), Population Genetics of Bacteria: A Tribute to Thomas S. Whittam, ASM Press, Washington DC. 31-42.
Minnick MF, Hicks LD, Battisti JM, Raghavan R. 2010. Pentamidine inhibits Coxiella burnetii 23S rRNA intron splicing and intracellular growth. Int J Antimicrob Agents 36: 380-382.
Hicks LD, Raghavan R, Battisti JM, Minnick MF. 2010. A DNA-binding peroxiredoxin of Coxiella burnetii is involved in countering oxidative stress during exponential-phase growth. J Bacteriol 192: 2077-2084.
Ochman H, Raghavan R. 2009. Excavating the functional landscape of bacterial cells. Science 326: 1200-1201.
Raghavan R, Minnick MF. 2009. Group I introns and inteins: disparate origins but convergent parasitic strategies. J Bacteriol 191: 6193-6202.
Raghavan R, Hicks LD, Minnick MF. 2009. A unique group I intron In Coxiella burnetii is a natural splice mutant. J Bacteriol. 191: 4044-4046.
Raghavan R, Hicks LD, Minnick MF. 2008. Toxic introns and parasitic intein in Coxiella burnetii: Legacies of a promiscuous past. J Bacteriol 190: 5934-5943.
Raghavan R, Miller SR, Hicks LD, Minnick MF. 2007. The unusual 23S rRNA of Coxiella burnetii: Two self-splicing group I introns flank a 34-base-pair exon and one element lacks the canonical ΩG. J Bacteriol 189: 6572-6579.
Battisti JM, Smitherman LS, Sappington KN, Parrow NL, Raghavan R, Minnick MF. 2007. Transcriptional regulation of the heme binding protein gene family of Bartonella quintana is accomplished by a novel promoter element and iron response regulator. Infect Immun 75: 4373-4385.
Nagaraj SR. Raghavan R, Maceden R, Kurpad AV. 2004. Intestinal parasitic infection and total serum IgE in asymptomatic adult males in an urban slum and efficacy of antiparasitic therapy. Indian J Med Microbiol. 22: 54-56.