Today, depression is undeniably one of the major public health concerns. This particular mental disorder is accompanied by worthlessness, exhaustion& sadness. It has already impacted around 320 million of individuals worldwide.The conventional therapies that are available today are not as effective as they should be. The rate of suicide is increasing at an alarming pace. Due to this, there is a requirement of developing novel, transformative interventions for curing depression. Some of psychedelics have shown their potential as interventions for depression. Although, it might be difficult to imagine that the elicit psilocybin, called as magic mushrooms can be utilized in clinical settings. However, it is exactly where the future of the mental health care industry life.