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This meeting will focus on natural products from terrestrial and marine origins and will be organized in collaboration with the Phytochemical Society of Europe and the Natural Products Institute of the College of Pharmacy of Seoul National University with the support of the International Association of Dietetic Nutrition and Safety (IADNS).
Friday, May 19, 2023
9:00 – 9:30: Introduction
Marc Diederich, Dong-Chan Oh, organizers
Sang Kook Lee, Dean of the College of Pharmacy, Seoul National University
Francisco A. Macias, President of the PSE
Session 1: Innovation in natural product discovery and utilization
(Chairs: Marc Diederich and Shim Sang Hee)
9:30 – 10:30: Keynote lecture 1: Macias Francisco A., University of Cádiz, Spain: Drug delivery of natural products by organic nanoencapsulation. Reducing the size, increasing the effect
10:30 – 11:00: Noh Minsoo, Seoul National University, South Korea: Machine learning models to predict the adiponectin-secretion-promoting activity of flavonoid-associated phytochemicals
11:00 – 11:30: Coffee break
11:30 – 12:00: Kang Kyo Bin, Sookmyung Women’s University, South Korea: Mass spectrometry-based qualitative metabolomics unearths chemistry of natural product biotransformation
12:00 - 12:30: Kim Seonbeom, Pusan National University, South Korea: New Technologies in Botanical Authenticity Analysis
12:30 – 14:00: Lunch break
Session 2: Innovation in medicinal and food compounds
(Chair: Noh Minsoo)
14:00 – 15:00: Keynote lecture 2: Silva Artur, University of Aveiro, Portugal: Underexplored species valorization: natural resources application in medicinal or nutritional formulations
15:00 – 15:30: Kim Ki Hyun: Sungkyunkwan University, South Korea: Discovery of bioactive natural products and application research through convergence studies
15:30 – 16:00: Mejías Francisco Javier Rodríguez, University of Cádiz, Spain: Host-guest complexation of photolarvicide. Natural product phototoxicity against malaria vectors.
16:00 – 16:30: Coffee break
16:30 – 17:30: Poster presentation session
17:30 - 18:30: Welcome reception
Saturday, May 20, 2023
Session 3: Innovation in marine drug discovery 1
(Chair: Artur Silva)
9:00 –10:00: Keynote lecture 3: Surh Young-Joon, Seoul National University, South Korea: Anti-inflammatory, Proresolving, and Chemopreventive Effects of Docosahexaenoic Acid, a Marine Treasure
10:00 – 10:30: Alves Celso, MARE – Marine and Environmental Sciences Centre, Peniche, Portugal: Seaweed-derived natural products as potential therapeutic agents for Parkinson’s disease treatment
10:30 – 11:00: Coffee break
Session 4: Innovation in marine drug discovery 2
(Chair: Alves Celso)
11:00 – 11:30: Detournay Olivier, PLANKTOVIE, France: Large-scale marine microalgae production for natural compounds isolation
11:30 – 12:00: Nam Sang-Jip, Ewha Womans University, South Korea: Bioactive Natural Products from the Marine-derived Fungus Acremonium sp. CNQ-049
12:00 – 12:30: Lorant Anne, LBMCC, Luxembourg: Synergistic Pro-apoptotic Effect of Xanthocillin X Dimethyl Ether with BH3 mimetics, Navitoclax and Venetoclax, in Acute Myeloid Leukemia
12:30 – 14:00: Lunch break
14:00 – 19:00: City trip and gala dinner (reservation only)
Sunday, May 21, 2023
Session 5: Natural products in health and disease 1
(Chair: Cerella Claudia)
9:00 – 9:30: Cuendet Muriel, Institute of Pharmaceutical Sciences of Western Switzerland University of Geneva, Switzerland: Withanolides against multiple myeloma
9:30 – 10:00: Lee Jung Weon, Seoul National University, South Korea: Specific inhibition of TM4SF5-mediated protein complex formations for chronic liver disease
10:00 – 10:30: Song Yong Sang, Seoul National University, South Korea: Exploring the Potential of Adipose-derived Stem Cells for Personalized Obesity Management
10:30 – 11:00: Coffee break
Session 6: Natural products in health and disease 2
(Chair: Cuendet Muriel)
11:00 – 11:30: Sieniawska Elwira, Medical University of Lublin, Poland: Natural products as adjuvants against Mycobacterium tuberculosis
11:30 – 12:00: Cerella Claudia, LBMCC, Luxembourg: Data-driven biomarkers predict myelomonocytic and monocytic acute myeloid leukemia patients as suitable candidates for cardiac glycosides
12:00 – 12:30: Boyer Barbora, LBMCC, Luxembourg: Antileukemic potential of methylated indolequinone MAC681 through immunogenic necroptosis and PARP1 degradation
12:30 – 14:30: Lunch break
Session 7: Bioactive compound discovery
(Chair: Surh Young-Joon)
14:30 – 15:00: Provot Olivier, Université Paris-Saclay, France: Combretastatin A4: a long and lovely medicinal chemistry story
15:00 – 15:30: Shim Sang Hee, Seoul National University, South Korea: Discovery of bioactive natural products from plant-associated microorganisms
15:30 – 16:00: Valentová Kateřina, Institute of Microbiology of the Czech Academy of Sciences, Prague, Czech Republic: Natural flavonolignans and their derivatives as prospective adjuvant therapeutics
16:00 – 16:30: Coffee break
Session 7: Selected short presentations
(Chairs: Marc Diederich and Dong-Chan Oh)
16:30 – 16:45: Natural compounds with hypolipidemic action. Elena Iuliana Ilie, Liliana Costea, Emanuela Alice Luta, Cerasela Elena Gird. “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
16:45 – 17:00: Investigation of HDAC6 inhibitor on deregulating autophagy, and the synergistic anticancer effect in combination with Asciminib in chronic myeloid leukemia. Ji Yeon Paik. College of Pharmacy, Seoul National University, Seoul, South Korea.
17:00 – 17:15: Cyclodextrin and cellulase induced isoflavonoids production in Pueraria candollei cell suspension culture. Worapol Sae-Foo, Gorawit Yusakul, Waraporn Putalun. Khon Kaen University, Khon Kaen, Thailand
End of the meeting
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