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Click here to view the full list of papers from the YUN Lab.
RECENT PUBLICATIONS
RECENT PUBLICATIONS
2025
Thermodynamically Coupled Three-Enzyme Cascade Converts Styrene to Cinnamic Acid, l-Phenylalanine, and Phenylpyruvate via CO2 Fixation without External Energy Cofactors
Thermodynamically Coupled Three-Enzyme Cascade Converts Styrene to Cinnamic Acid, l-Phenylalanine, and Phenylpyruvate via CO2 Fixation without External Energy Cofactors
Sunga Cho, Ye Chan Kim, Amol D. Pagar, Sangwoo Joo, Pritam Giri, Subin Yun, Geon-Woo Park, Young-Soo Keum, Hyungdon Yun
ACS Synthetic Biology Published September 5, 2025 https://doi.org/10.1021/acssynbio.5c00384
Integrated cascade biocatalysis of cannabigerolic acid through cyclodextrin-mediated stabilization and prenyltransferase engineering
Integrated cascade biocatalysis of cannabigerolic acid through cyclodextrin-mediated stabilization and prenyltransferase engineering
Ye Chan Kim, Hyunseok Yoon, Youngwoo Na, Rohan Ghosh, Seohee Jung, Young Hwan Goh, Sangwoo Joo, Seunho Jung, Boyoung Y Park, Tae Hyeon Yoo, Suhyun Park, Munikumar Reddy Doddareddy, Sangwook Wu, Hyungdon Yun
Bioresource Technology Published August 25, 2025
https://doi.org/10.1016/j.biortech.2025.133190
Development of in vitro ribosome assembly system for ribosome engineering with ribosome biogenesis factors YrdC and SrmB
Development of in vitro ribosome assembly system for ribosome engineering with ribosome biogenesis factors YrdC and SrmB
Youkyoung Kwon · Minyeong Maeng · Sangwoo Joo · Yechan Kim · Taresh P. Khobragade · Pritam Giri · Rohan Ghosh · Seohee Jung · Hyunseok Yoon · Sunga Cho · Subin Yun · Sanghun Jeong · Taek Jin Kang · Joongoo Lee · Hyungdon Yun Biotechnology and Bioprocess Engineering Published June 25, 2025https://link.springer.com/article/10.1007/s12257-025-00205-x
Elucidation of Broad Substrate Specificity of a Novel γ-Glutamyl Transferase from Bacillus atrophaeus and Rational Design for Enhanced Substrate Selectivity
Elucidation of Broad Substrate Specificity of a Novel γ-Glutamyl Transferase from Bacillus atrophaeus and Rational Design for Enhanced Substrate Selectivity
Subin Yun,Ye Chan Kim,Rohan Ghosh,Deok Mo Song,Sangwoo Joo,Taresh Khobragade,Pritam Giri,Sunga Cho,Choong Hwan Lee,Hyungdon YunJournal of Agricultural and Food Chemistry Published June 10, 2025 https://pubs.acs.org/doi/10.1021/acs.jafc.5c02661
High-Concentration Production of l-Theanine from l-Glutamate Derived from Fermentation Using Novel GMAS and ATP Regeneration with Co-Immobilized Hybrid Nanoflower
High-Concentration Production of l-Theanine from l-Glutamate Derived from Fermentation Using Novel GMAS and ATP Regeneration with Co-Immobilized Hybrid Nanoflower
Subin Yun,Ye Chan Kim,Seonga Lim,Taresh P. Khobragade,Pritam Giri,Sangwoo Joo,Rohan Ghosh,You Kyoung Kwon,Hyunseok Yoon,Sunga Cho,Seohee Jung,Min Yeong Maeng,Sang Hun Jeong,Hyungdon YunACS Food Science & Technology Published March 31, 2025 https://pubs.acs.org/doi/epdf/10.1021/acsfoodscitech.4c00993
2024
Tuning of Protein Expression by Promoter Engineering
Tuning of Protein Expression by Promoter Engineering
Taresh P. Khobragade, Pritam Giri, Hyungdon Yun
Methods in molecular biology 2024
https://link.springer.com/protocol/10.1007/978-1-0716-4063-0_13
Biocatalysis enables the scalable conversion of biobased furans into various furfurylamines
Biocatalysis enables the scalable conversion of biobased furans into various furfurylamines
Pritam Giri, Seonga Lim, Taresh P. Khobragade, Amol D. Pagar, Mahesh D. Patil, Sharad Sarak, Hyunwoo Jeon, Sangwoo Joo, Younghwan Goh, Seohee Jung, Yu-Jeong Jang, Seung Beom Choi, Ye Chan Kim, Taek Jin Kang, Yong-Seok Heo, Hyungdon Yun
Nature Communications Published: 29 July 2024
One-Pot Biocatalytic Route from Alkanes to α,ω-Diamines by Whole-Cell Consortia of Engineered Yarrowia lipolytica and Escherichia coli
One-Pot Biocatalytic Route from Alkanes to α,ω-Diamines by Whole-Cell Consortia of Engineered Yarrowia lipolytica and Escherichia coli
Ye Chan Kim, Hee-Wang Yoo, Beom Gi Park, Sharad Sarak, Ji-Sook Hahn, Byung-Gee Kim, and Hyungdon Yun.
ACS Synthetic Biology Published: June 2024
Development of in vitro lycopene biosynthesis from geranyl pyrophosphate employing cell-free protein synthesis
Development of in vitro lycopene biosynthesis from geranyl pyrophosphate employing cell-free protein synthesis
Young Hwan Goh, Ye Chan Kim, Sang Hun Jeong, Sangwoo Joo, You Kyoung Kwon, Hyunseok Yoon, Seohee Jung, Taresh P. Khobragade, Pritam Giri, Seonga Lim, Subin Yun, Sunga Cho, Sang Hyun Lee, Woo-Jae Chung, Jae Eun Lim, Taek Jin Kang & Hyungdon Yun
Biotechnology and Bioprocess Engineering Published: 25 May 2024 https://link.springer.com/article/10.1007/s12257-024-00111-8
Exemplifying Natural (R)-β-Transamination Potential of Fold Type-IV Transaminase for Kinetic Resolution of rac-β-Amino Acids Synthesized from Aldehydes
Exemplifying Natural (R)-β-Transamination Potential of Fold Type-IV Transaminase for Kinetic Resolution of rac-β-Amino Acids Synthesized from Aldehydes
Amol D Pagar, Taresh P Khobragade, Pritam Giri, Hyunwoo Jeon, Sungchan Cho, Seohee Jung, Younghwan Goh, Sangwoo Joo, Sharad Sarak, Ganapathiraman Munussami, Sun-Gu Lee, Hyungdon Yun
ACS Sustainable Chemistry & Engineering Published April 26, 2024
Biocatalytic Cascade for Synthesis of Sitagliptin Intermediate Employing Coupled Transaminase
Biocatalytic Cascade for Synthesis of Sitagliptin Intermediate Employing Coupled Transaminase
TP Khobragade, AD Pagar, P Giri, S Sarak, H Jeon, S Joo, Y Goh, ...
Biotechnology and Bioprocess Engineering 28 (2), 300-309 Published: 15 May 2023
https://link.springer.com/article/10.1007/s12257-023-0085-5
2023
Biocatalytic Cascade for Synthesis of Sitagliptin Intermediate Employing Coupled Transaminase
TP Khobragade, AD Pagar, P Giri, S Sarak, H Jeon, S Joo, Y Goh, ...
Biotechnology and Bioprocess Engineering 28 (2), 300-309
AD Pagar, S Cho, S Jung, H Yoon, H Yun
KSBB Journal 38 (1), 28-34
TP Khobragade, P Giri, AD Pagar, MD Patil, S Sarak, S Joo, Y Goh, ...
Frontiers in Bioengineering and Biotechnology 11
S Sarak, AD Pagar, TP Khobragade, H Jeon, P Giri, S Lim, MD Patil, ...
Green Chemistry 25 (2), 543-549
2022
Creation of a (R)-β-Transaminase by Directed Evolution of d-Amino Acid Aminotransferase
H Jeon, AD Pagar, H Kang, P Giri, SP Nadarajan, S Sarak, ...
ACS Catalysis 12 (21), 13207-13214
Light‐Triggered In Situ Biosynthesis of Artificial Melanin for Skin Protection
UJ Lee, J Ko, SH Kim, PG Lee, YH An, H Yun, DT Flood, PE Dawson, ...
Advanced Science 9 (7), 2103503
Non-canonical amino acid-based engineering of (R)-amine transaminase
AD Pagar, H Jeon, TP Khobragade, S Sarak, P Giri, S Lim, TH Yoo, BJ Ko, ...
Frontiers in chemistry 10, 839636
HW Yoo, H Jung, S Sarak, YC Kim, BG Park, BG Kim, MD Patil, H Yun
Green Chemistry 24 (5), 2222-2231
2021
Chemical modification of enzymes to improve biocatalytic performance
P Giri, AD Pagar, MD Patil, H Yun
Biotechnology Advances 53, 107868
EY Hong, SG Lee, H Yun, BG Kim
Frontiers in Catalysis 1, 774512
TP Khobragade, S Sarak, AD Pagar, H Jeon, P Giri, H Yun
Frontiers in bioengineering and biotechnology 9, 757062
TP Khobragade, S Yu, H Jung, MD Patil, S Sarak, AD Pagar, H Jeon, ...
Biotechnology and Bioengineering 118 (8), 3263-3268
A multi-enzyme cascade reaction for the production of α, ω-dicarboxylic acids from free fatty acids
S Lim, H Yoo, S Sarak, B Kim, H Yun
Journal of Industrial and Engineering Chemistry 98, 358-365
S Lee, H Jeon, P Giri, UJ Lee, H Jung, S Lim, S Sarak, TP Khobragade, ...
Biotechnology and Bioprocess Engineering 26, 384-391
Recent advances in biocatalysis with chemical modification and expanded amino acid alphabet
AD Pagar, MD Patil, DT Flood, TH Yoo, PE Dawson, H Yun
Chemical Reviews 121 (10), 6173-6245
S Sarak, S Sung, H Jeon, MD Patil, TP Khobragade, AD Pagar, ...
Angewandte Chemie International Edition 60 (7), 3481-3486
S Sarak, TP Khobragade, H Jeon, AD Pagar, P Giri, S Lee, H Yun
Green Chemistry 23 (23), 9447-9453
2020
S Sarak, H Jeon, MD Patil, TP Khobragade, AD Pagar, S Sung, HW Yoo, ...
Catalysis Letters 150, 3079-3085
S Ko, H Jeon, S Yoon, M Kyung, H Yun, JH Na, ST Jung
Journal of agricultural and food chemistry 68 (21), 5873-5879
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