Past and Present Research Projects

Research Projects as Principal Investigator

1) “Design and Development of Tissue Selective Antiestrogens” (File No. SR/FTP/CSA-05/2002) of worth Rs. eleven lakhs, DST, New Delhi (2003- 2006).

2) “Design and Synthesis of Novel SERMs (Selective Estrogen Receptor Modulators) for the management of Osteoporosis and other estrogen related disorders” (File No. 58/1/2003-BMS) of Rs. seventeen lakhs, ICMR, New Delhi (2003-2006)- 58/1/2003-BMS.

3) “Diversity Oriented Organic Synthesis of Small but Smart Molecules in Drug Discovery Research” (File No. SR/S1/OC-23/2005) of worth Rs. twenty lakhs, DST, New Delhi (2006-2009).

4) “Amino Acids as chiral Synthons: Development of new synthetic protocols for creating Natural Products and related diversity in quest for anticancer agent” (File No. SR/S1/OC-74/2009) of Rs. 35 lakhs, DST, New Delhi (2010-2013).

5) Project Coordinator from CDRI on “Synthetic Biology (Metabolic Engineering of Vinca Alkaloid Pathway (Rs 81 lakhs) and Metabolic Engineering of Azadirachtin biosynthetic pathway (Rs 35 lakhs)” (2010-2013)

6) “Design, synthesis and evaluation of new chemical entities against atypical mycobacterium, Mycobacterium fortuitum” of Rs. 40 lakhs, ICMR, New Delhi (2011-2013)- IRIS ID: 2009-04190.

7) “Quest for Corannulene based Polyfunctional Molecules in Nanobiotechnology and Nanomedicine: Transporting and Translocating properties of Corannulene derived carrier systems” (File No. SB/S1/OC-93 /2013) of Rs 53 lakhs, DST, New Delhi (2015-2018).

8) Ligand and structure-based screening of designed and synthesized chemical library around Psammaplin A against DNA methyltransferase 1 (DNMT1) and Diversity oriented synthesis of Halimide & Phenylahistin related analogs as anticancer agents (File No. MoES/09-DS/3/201P5C –IV), of Rs 45 lakhs (2016-2019) from MoES, New Delhi.

9) "Amino acids derived steroidal and non-steroidal Ligands as inhibitors of steroid 5-α-reductase in cancer" (File No. 3511410812018-BRNS/35032) of Rs 35 lakhs from BRNS (2018-2021)

10) “Inhibition of ATP synthase enzyme of drug-resistant Mycobacterium tuberculosis through chemical library of Asymmetric Tri and Tetrasubstituted methanes (TRSMs) and ethanes (TRSEs)” (File No. SERB/F/8968/2019-2020) of Rs 45 lakhs from DST ongoing (2020-todate).

11)   Cost Effective Route of Nitisinone for Alkaptonuria and Hereditary Tyrosinemia-1 (HT-1) from DST approved

12)   Process for Acyclovir and Sulbactam from DST approved 

Research Projects as Team Member

1) "Making cancer care affordable; Empowering Women’s Health: Focusing on Breast and Gynaecological Cancers of Indian Relevance" by PAN-CSIR Cancer Program

2) “Novel and integrative approaches towards discovery of small molecule therapeutics for healthy ageing (NISTHA)" by in house CSIR project

3) “Investigating the host-parasite determinants of survival, virulence and immunity in Malaria" by CSIR network project 

4) "Molecules for Anti Mycobacterial Resistance (AMR)" by CSIR

5) Chemical biology approaches towards dissecting non-canonical protein functions and novel targets in the Malaria, Leishmania and Filaria parasites (MLP 2031--NCP)

6) Bucky-Bowl Based Small Peptides-Doxorubicin Co-assembly for tumor cell treatment (CII7063)