Professional Experience and Education
Professional experience
Feb 2023 - Till date
Manager - Bioinformatics (Drug Discovery)
Elanco IAC, Bangalore, IndiaFeb 2019 - Feb 2023
Sr. Scientist II (Application Science)
Schrodinger Inc., Bangalore, IndiaJan 2017 - Feb 2019
Postdoctoral Research Associate
Center for Molecular Biology (ZMBH),University of Heidelberg,Im Neuenheimer Feld 282, 69120 Heidelberg, Germany.Supervisor: Prof. Dr. Rebecca WadeJan 2015 - Jan 2017
Postdoctoral Research Associate
Molecular and Cellular Modeling group, Heidelberg Institute of Theoretical Studies (HITS),Schloß-Wolfsbrunnenweg 35, 69118 Heidelberg, Germany.Supervisor: Prof. Dr. Rebecca WadeEducation
2010 - 2014
Ph.D. in Pharmacoinformatics, with cGPA of 8.50 on a 10 point scale.
Thesis title: Cytochrome P450 1A1: Molecular Modeling Guided Design and In Vitro Studies of Anticancer Compounds and CYP1A1-Biomembrane Interactions.Supervisor: Dr. Abhay Sangamwar, Department of Pharmacoinformatics, National Institute of Pharmaceutical Education and Research (NIPER), S.A.S. Nagar, Punjab, India, Pin code: 160062 andCo-supervisor: Prof. Rebecca Wade, HITS gGmbH, Heidelberg, Germany.
2008 - 2010
M. S. (Pharm.) Pharmacoinformatics, with cGPA of 9.02 on a 10 point scale.
Thesis title: Cytochrome P450 2C19 mediated metabolism of drugs: Molecular docking and MetaSite analysisSupervisor: Prof. Prasad V. Bharatam, Department of Medicinal Chemistry, NIPER, S.A.S. Nagar.2004 - 2008
Bachelor of Pharmacy (B. Pharm.) with 65.95% marks.
University Department of Pharmaceutical Sciences, Nagpur University, Nagpur, India.2003
Higher Secondary School Certificate Exam, with 81.03% marks.Nabira Mahavidyalaya, Katol, Dist. Nagpur, India2001
Secondary School Certificate Exam, with 80.60% marks.Nagar Parishad High School, Katol, Dist. NagpurTeaching Experience
Assistance in conducting practical classes for M.S. (Pharm.) students, taught Chemoinformatics in drug discovery at National Institute of Pharmaceutical Education and Research (NIPER), SAS Nagar, India.
Conducted “Training and practical session on MetaSite and TOPKAT software” in Drug Metabolism and Pharmacokinetics (DMPK) symposium 2010, 2011, 2012 and 2013 at NIPER, S.A.S. Nagar, India.
Teaching assistance in Basic Bioinformatics course for Undergraduates at University of Heidelberg, in 2016, 2017, taught practical aspects of protein modeling, structure‑based and ligand‑based drug design.
Technical Expertise
Chem-Bioinformatics software: Tripos Sybyl 7.1, Schrödinger Suite, Accelrys Discovery Studio, CCG MOE, Cambridge ChemOffice 2010
Molecular docking: FlexX, Glide, InduceFit, Autodock, GOLD, LeadIT, CDOCKER
Visualizer: Maestro, Silver, BiosolveIT, Pymol, VMD, Chimera
Homology modeling: Modeller, Prime, Biopolymer
ADMET prediction: GastroPlus (Simulations Plus, Inc), Dragon, TOPKAT, DEREK, MetaSite, ADMET predictor, ACD labs, QuickProp
Molecular dynamics: Gromacs, Amber, NAMD
Quantum chemistry: Gaussian
Scientific workflow system: Pipeline Pilot and KNIME
Data Mining/Statistics software: R package, MATLAB, RapidMiner, Sigmastat, GNU plot, SQL Data mining add-in in MS Excel
Programming/Scripting skills: C++, Perl, Python, Bash shell scripting
Hardware and operating systems: Sun workstation, Core Cluster on Linux, SGI Tezro, Fuel, Windows, IRIX, LINUX
Other software: MS Access, M.S. Excel, Endnote, etc.