Publications

Hyunki Kim, Yan Li, Houxiang Zhu, Namrata Shukla, Michael A. Glass, Joan Sabadell-Basallote, Khadija El Jellas, Ziyou Ren, Kazuki Fukuda, Katherine H. Xu, Elizabeth M. Seider, Linda T. Nieman, Maria Ericsson, Mengjie Chen†, Rohit N. Kulkarni†. Compensatory signatures of β-cells and islet stellate cells that protect obese humans from diabetes. In revision. (†co-corresponding authors)

Hyunki Kim*, Namrata Shukla*, Khadija El Jellas, Hui Pan, Jonathan M. Dreyfuss, Michael A. Glass, Joan Sabadell-Basallote, Jiang Hu, Jun Shirakawa, Kazuki Orime, Rohit N. Kulkarni. Nuclear insulin receptors associate with RFX6 to shape the transcriptional landscape of human β-cells. In revision. (*equally contributed to this work) 

Einer Carlos Eduardo Arevalo-Rios, Roselyn Mateo-Collado, Hyunki Kim, Elvira Isganaitis, Rohit N. Kulkarni, Mary-Elizabeth Patti (2026) Long QT syndrome and hypoglycemia in a postbariatric surgery patient with a likely pathogenic variant in KCNE1. JCEM Case Reports 4(7):luag094.

Hyunki Kim, Rohit N. Kulkarni (2026) Insulin/IGF signaling in islet biology and its therapeutic implications. Endocrine Reviews bnag014. (Invited review article) 

Yichao Zhou, Sarah Sumner, Temidayo Adeluwa, Lisha Zhu, Sofia Salazar-Magaña, Hyunki Kim, Saideep Gona, Festus Nyasimi, Rohit N. Kulkarni, Joseph E. Powell, Ravi Madduri, Boxiang Liu, Mengjie Chen†, Hae Kyung Im† (2026) Protocol to perform cell-type-specific transcriptome-wide association study using scPrediXcan framework. STAR Protocols 7(1):104306. (†co-corresponding authors) 

Yichao Zhou, Temidayo Adeluwa, Lisha Zhu, Sofia Salazar-Magaña, Sarah Sumner, Hyunki Kim, Saideep Gona, Festus Nyasimi, Rohit N. Kulkarni, Joseph E. Powell, Ravi Madduri, Boxiang Liu, Mengjie Chen†, Hae Kyung Im† (2025) scPrediXcan integrates deep learning methods and single-cell data into a powerful cell-type-specific transcriptome-wide association study framework. Cell Genomics 5(5):100875. (†co-corresponding authors) 

Sevim Kahraman, Kimitaka Shibue, Dario F. De Jesus, Hyunki Kim, Jiang Hu, Debasish Manna, Bridget Wagner, Amit Choudhary, Rohit N. Kulkarni (2023) Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses. eLife 12:e85056. 

Tomozumi Takatani*, Jun Shirakawa*, Kimitaka Shibue*, Manoj K. Gupta, Hyunki Kim, Shusheng Lu, Jiang Hu, Morris F. White, Robert T. Kennedy, Rohit N. Kulkarni (2021) Insulin receptor substrate 1, but not IRS2, plays a dominant role in regulating pancreatic alpha cell function in mice. Journal of Biological Chemistry 296:100646.(*equally contributed to this work)

Hyunki Kim, Rohit N. Kulkarni (2020) Epigenetics in β-cell adaptation and type 2 diabetes. Current Opinion in Pharmacology 55:125-131. (Invited review article)

Joon Ho Moon*, Hyeongseok Kim*, Hyunki Kim, Jungsun Park, Wonsuk Choi, Wongun Choi, Hyun Jung Hong, Hyun-Joo Ro, Sangmi Jun, Sung Hee Choi, Ronadip R. Banerjee, Minho Shong, Nam Han Cho, Seung K. Kim, Michael S. German†, Hak Chul Jang†, Hail Kim† (2020) Lactation improves pancreatic β cell mass and function through serotonin production. Science Translational Medicine 12(541):eaay0455. (*equally contributed to this work) (†co-corresponding authors) 

Jiyoon Kim, Hyeyon Kim, Shin Hye Noh, Dong Geon Jang, Shi-Young Park, Dongkook Min, Hyunki Kim, Hee-Seok Kweon, Hoguen Kim, Sowon Aum, Sookyung Seo, Cheol Soo Choi, Hail Kim, Jae Woo Kim, Seok Jun Moon, Heon Yung Gee, Min Goo Lee (2020) Grasp55−/− mice display impaired fat absorption and resistance to high-fat diet-induced obesity. Nature Communications 11(1):1418.

Hyunki Kim*, Byoung-Ha Yoon*, Chang-Myung Oh*, Joonyub Lee*, Kanghoon Lee, Heein Song, Eunha Kim, Kijong Yi, Mi-Young Kim, Hyeongseok Kim, Yong Kyung Kim, Eun-Hye Seo, Haejeong Heo, Hee-Jin Kim, Junguee Lee, Jae Myoung Suh, Seung-Hoi Koo, Je Kyung Seong, Seyun Kim, Young Seok Ju, Minho Shong, Mirang Kim†, Hail Kim† (2020) PRMT1 Is Required for the Maintenance of Mature β-Cell Identity. Diabetes 69(3):355-368. (*equally contributed to this work) (†co-corresponding authors) 

Kanghoon Lee*, Hyunki Kim*, Joonyub Lee, Chang-Myung Oh, Heein Song, Hyeongseok Kim, Seung-Hoi Koo, Junguee Lee, Ajin Lim, Hail Kim (2019) Essential Role of Protein Arginine Methyltransferase 1 in Pancreas Development by Regulating Protein Stability of Neurogenin 3. Diabetes & Metabolism Journal 43(5):649-658. (*equally contributed to this work)

Hyeongseok Kim, Hyunki Kim, Kyuho Kim, Michael S. German, Hail Kim (2018) Ectopic serotonin production in β-cell specific transgenic mice. Biochemical and Biophysical Research Communications 495(2):1986-1991.