Plant Cell Polarity 

Research Overview:

Cell polarity plays a crucial role in shaping the organization and function of cells, influencing various developmental and physiological processes in both animals and plants. In the Dong Lab, we focus on understanding the molecular mechanisms behind cell polarity in plants, particularly in the model organism Arabidopsis thaliana. Our research centers on the BASL (Breaking of Asymmetry in the Stomatal Lineage) protein and other polarity factors that are integral to establishing cellular asymmetry in plant development and growth.

We investigate how polarity proteins are spatially localized within plant stem cells, and how this localization is linked to cellular differentiation and fate determination during asymmetric cell division. By examining the protein dynamics of polarity establishment during different stages of the stomatal lineage cells, our work aims to uncover the broader principles governing the orchestrated activities of signaling molecules required for the progression of cell division and fate differentiation. These insights not only contribute to our understanding of plant development but also hold potential for improving agricultural practices and advancing cellular biology.