Research

Pictorial representation of immune synapse and proposed work.

A) A simplified diagram illustrating the structure of membrane-bound TCRs and soluble bispecific TCRs, with an estimation of the immune synapse's probable length. The design includes a pentagon-shaped "plug-and-play" molecule to represent the proposed modular format. B) CDR loops, represented as straight lines, are paired with the engineered molecule, while antigen structures are shown as zig-zag lines. To facilitate visualization, each CDR loop is color-coded to match its corresponding straight-line form, providing clarity on their alignment and interactions.