Nuckols VR, Davis KG, Smith M, Carey ML, Bell B, Santillan MK, Santillan DA, Pierce GL (2025). Association of physical activity, sedentary time and sleep with maternal vascular function in women with a history of preeclampsia. J Appl Physiol Jun 30 doi: 10.1152/japplphysiol.00928.2024. Online ahead of print.
Gimblet CJ, Donato AJ, Jalal DI, Pierce GL (2025). Sex differences in endothelial glycocalyx thickness and the response to glycocalyx-targeted therapy among older adults. Physiol Rep, 13(12):e70428.
Nuckols VR, Davis KG, Santillan MK, Santillan DA, Pierce GL (2025). Long-term effects of parity on maternal autonomic function. Autonom Neurosci, May 2:260:103285. doi: 10.1016/j.autneu.2025. 103285. Online ahead of print.
Pierce G.L. (2024). De-stiffening the aged aorta with regular aerobic exercise in humans: fact or fallacy? Pulse, 13(1):22-30.
Wakeham D, Pierce GL, Heffernan KS (2025). Effect of acute resistance exercise and resistance exercise training on central pulsatile hemodynamics and large artery stiffness: part I. Pulse, 13(1):31-44.
Wakeham D, Pierce GL, Heffernan KS (2025). Effect of acute resistance exercise and resistance exercise training on central pulsatile hemodynamics and large artery stiffness: part II. Pulse, 13(1):45-61
Nuckols VR, Davis KG, Pierce GL, Gibbs B, Whitaker KM (2025). Associations of physical activity and sedentary time with aortic stiffness and autonomic function in early pregnancy (2025). J Appl Physiol, 138(3):774-782.
Borrowman JD, Carr LJ, Pierce GL, Story WT, Gibbs BB, Whitaker KM (2025). Postpartum remote health coaching intervention for individuals with a hypertensive disorder of pregnancy: proof-of-concept study. JMIR Form Res, Jan 8;9:e656611.
Jae SY, Lee KH, Kim HJ, Kunutsor SK, Pierce GL, Hui SS, Kang M. Association Between Cardiorespiratory Fitness and Trend of Age-Related Rise in Arterial Stiffness in Individuals With and Without Hypertension or Diabetes. Am J Hypertens. 2024 Dec 16;38(1):46-54. doi: 10.1093/ajh/hpae124
Gimblet CJ, Kruse NT, Geasland K, Michelson J, Sun M, Mandukhail SR, Wendt LH, Eyck PT, Pierce GL, Jalal DI. Effect of Resveratrol on Endothelial Function in Patients with CKD and Diabetes: A Randomized Controlled Trial. Clin J Am Soc Nephrol. 2024; Feb 1;19(2):161-168.
Gimblet CJ, Kruse NT, Geasland K, Michelson J, Sun M, Mandukhail SR, Wendt LH, Eyck PT, Pierce GL, Jalal DI. Effect of resveratrol on endothelial function in patients with CKD and diabetes: A randomized controlled trial. Clin J Am Soc Neprhol 2023;19(2):161-168.
Vignato JA, Gumusoglu SB, Davis HA, Scroggins SM, Hamilton WS, Brandt DS, Pierce GL, Knosp BA, Santillan DA, Santillan MK. Selective Serotonin Reuptake Inhibitor Use in Pregnancy and Protective Mechanisms in Preeclampsia. Reprod Sci. 2023; Feb;30(2):701-712.
Armstrong MK, Chirinos JA, Kapuku GK, Pierce GL. Aortic pressure-only wave separation analysis in adolescents: accuracy and associations with left ventricular mass index. J Hum Hypertens 2023;37(12):1119-1125. Read article.
Nuckols VR, Stroud AK, Armstrong MK, Brandt DS, Santillan MK, Santillan DA, Pierce GL. Postpartum ambulatory and home blood pressure monitoring in women with history of preeclampsia: Diagnostic agreement and detection of masked hypertension. Pregnancy Hypertens. 2022; Aug; 29:23-29.
Oh M, Jacobs DR, Gabriel KP, Bao W, Pierce GL, Carr LJ, Ding J, Whitaker KM. Cross-sectional and longitudinal associations of lifestyle behaviors with pericardial adipose tissue: the MESA study. Med Sci Sports Exer. 2022; 54(6):984-993.
Nuckols VR, Stroud A, Huesner J, Brandt D, DuBose L E, Santillan D, Santillan MK, Pierce GL. (2021). Twenty-four hour blood pressure variability is associated with lower cognitive function in young women with a history of preeclampsia. Am J Hypertens 34(12):1291-1299.
Pierce GL, Coutinho TA, DuBose LE, Donato AJ. Is it good to have a stiff aorta: causes and consequences. Physiology 2022 1;37(3):154-173. Read article.
DuBose LE, Weng TB, Pierce GL, Wharff C, Reist L, Hamilton C, O'Deen A, Dubishar KM< Lane-Cordova AD, Voss MW. Association between cardiorespiratory fitness and cerebrovascular reactivity to a breath hold stimulus in older adults: influence of aerobic exercise training. J Appl Physiol 2022 Apr 28. doi: 10.1152/japplphysiol.00599.2021. Online ahead of print. Read article
Oh M, Gabriel KP, Jacobs DR, Bao W, Pierce GL, Carr LJ, Terry JG, Ding J, Carr JJ, Whitaker KM. Cardiorespiratory fitness in adults aged 18 to 34 years and long-term pericardial adipose tissue (from the coronary artery risk Development in Adults Study- CARDIA). Am J Cardiol 2022 Mar 19;S0002-9149(22)00186-2. doi: 10.1016/j.amjcard.2022.02.031.
Kumar R, Sonkar VK, Swamy J, Ahmed A, Sharathkumar AA, Pierce GL, Dayal S. DNase 1 protects from increased thrombin generation and venous thrombosis during aging: cross-sectional study in mice and humans. J Am Heart Assoc 2022;11(2):e021188. Read article
Fiedorowicz JG, Dindo L, Ajibewa T, Persons J, Marchman, Holwerda SW, Abosi OJ, DuBose LE, Wooldridge N, Myers JL, Stroud AK, Dubishar K, Liu Z, Pierce GL. One-day acceptance and commitment therapy (ACT) workshop improves anxiety but not vascular function or inflammation in adults with moderate to high anxiety levels in a randomized controlled trial. Gen Hosp Psych 2021 Nov-Dec;73:64-70. Read article
Dindo L, Fiedorowicz JG, Boykin DM, Wooldridge N, Myers JL, Ajibewa T, Stroud A, Kuwaye D, Liu Z, Pierce GL A randomized controlled trial for symptoms of anxiety and depression: Effects of a one-day Acceptance and Commitment Training Workshop. Annals of Clin Psych 2021. Nov;33(4):258-269. doi: 10.12788/acp.0046. Read article
Nuckols VR, Stroud AK, Huesner JF, Brandt DS, DuBose LE, Santillan DA, Santillan MK, Pierce GL. Twenty-four hour Blood Pressure Variability is Associated with Lower Cognitive Performance in Young Women with a Recent History of Preeclampsia. Am J Hypertens 2021. Jul 19;hpab112. doi: 10.1093/ajh/hpab112. Online ahead of print. Read article
Pierce GL, Roy SJ, Gimblet CJ. The gut-arterial stiffness axis: Is TMAO a novel target to prevent age-related aortic stiffening? Hypertension 2021;78:512-515. Read article
Reho JJ, Guo DF, Beyer AM, Wegman-Points L, Pierce GL, Rahmouni K. Vascular Effects of Disrupting Endothelial mTORC1 (Mechanistic Target of Rapamycin Complex 1) Signaling in Obesity. Am J Physiol Regul Integr Comp Physiol 2021 Jun 30 doi: 10.1152/ajpregu.00113.2021. Online ahead of print. Read article
Luehrs RE, Moreau KL, Wamboldt F, Aloia M, Weinberger H, Make B, Crapo JD, Pierce GL, Hoth KF. Cognitive Performance is Lower Among Individuals with Overlap Syndrome than with COPD or Obstructive Sleep Apnea Alone: Role of Carotid Artery Stiffness. J Appl Physiol. 2021 May 13. doi: 10.1152/japplphysiol.00477.2020. Read Article
Stanhewicz AE, Nuckols VR, Pierce GL. Maternal microvascular dysfunction during preeclamptic pregnancy. Clinical Science. 2021 May 14;135(9):1083-1101. doi: 10.1042/CS20200894. Read Article
Luehrs RE, Zhang D, Pierce GL, Jacobs D, Kalhan R, Whitaker KM. Cigarette Smoking and Longitudinal Associations with Blood Pressure: The CARDIA Study. J Amer Heart Assoc. 2021 May 4;10(9):e019566. doi: 10.1161/JAHA.120.019566. Read Article
Santillan MK, Becker R, Calhoun DA, Cowley AW, Grobe JL, Kotchen TA, Lackland DT, Leslie KK, Liang M, Mattson DL, Meyers KE, Mitsnefes MM, Muntner PM, Pierce GL, Pollock JS, Sigmund CD, Thomas SJ, Urbina EM, Kidambi S. Team Science - American Heart Association’s HTN Strategically Focused Research Network Experience. Hypertension 2021;77:1857-1866. Read Article
Holwerda SW, Carter JR, Yang H, Wang J, Pierce GL, Fadel PJ. CORP: Standardizing methodology for assessing spontaneous baroreflex control of muscle sympathetic nerve activity in humans. Amer J Physiol Heart Circ Physiol 2021;320:H762-H771. Read Article
Holwerda SW, Holland MT, Green AL, Pearson ACS, Pierce GL. Dissociation between reduced pain and arterial blood pressure following epidural spinal cord stimulation in patients with chronic pain: A retrospective study. Clin Auton Res. 2021; 31(2):303-316. Read Article
Nuckols VR, Holwerda SW, Luehrs RE, DuBose LE, Stroud AK, BrandT D, Betz AM, Fiedorowicz JG, Scroggins SM, Santillan DA, Grobe JL, Sigmund CD, Santillan MK, Pierce GL. Beat-to-beat blood pressure variability in the first trimester is associated with the development of preeclampsia in a prospective cohort: relation with aortic stiffness. Hypertension 2020;76:1800-1807. Read Article
Holwerda SW, Kardon RH, Hashimoto R, Full JM, Nellis JK, DuBose LE, Fiedorowicz JG, Pierce GL. Aortic stiffness is associated with changes in retinal arteriole flow pulsatility mediated by local vasodilation in healthy young/middle-age adults. J Appl Physiol. 2020 Jul 1;129(1):84-93. Read Article
Barnard CR, Peters M, Sindler AL, Farrell ET, Baker KR, Palta M, Stauss HM, Dagle JM, Segar J, Pierce GL, Eldridge MW, Bates ML. Increased aortic stiffness and elevated blood pressure in response to exercise in adult survivors of prematurity. Physiol Rep. 2020 Jun;8(12):e14462. Read Article
Hoth KF, Moreau KL, Weinberger HD, Holm KE, Meschede K, Crapo JD, Make BJ, Moser DJ, Kozora E, Bowler RP, Pierce GL, Ten Eyck P, Wamboldt FS. Carotid Artery Stiffness is Associated With Cognitive Performance in Former Smokers With and Without Chronic Obstructive Pulmonary Disease. J Am Heart Assoc. 2020 May 5;9(9):e014862. Read Article
Perschbacher KJ, Deng G, Sandgren JA, Walsh JW, Witcher PC, Sapouckey SA, Owens CE, Zhang SY, Scroggins SM, Pearson NA, Devor EJ, Sebag JA, Pierce GL, Fisher RA, Kwitek AE, Santillan DA, Gibson-Corley KN, Sigmund CD, Santillan MK, Grobe JL. Reduced mRNA Expression of RGS2 (Regulator of G Protein Signaling-2) in the Placenta Is Associated With Human Preeclampsia and Sufficient to Cause Features of the Disorder in Mice. Hypertension 2020 Feb;75(2):569-579. Read Article
Voss MW, Weng TB, Narayana-Kumanan K, Cole RC, Wharff C, Reist L, Dubose L, Sigurdsson G, Mills JA, Long JD, Magnotta VA, Pierce GL. Acute exercise effects predict training change in cognition and connectivity. Med Sci Sports Exerc. 2020 Jan;52(1):131-140. Read Article
Cole RC, Hazeltine E, Weng TB, Wharff C, DuBose LE, Schmid P, Sigurdsson G, Magnotta VA, Pierce GL, Voss MW. Cardiorespiratory fitness and hippocampal volume predict faster episodic associative learning in older adults Hippocampus. 2020 Feb;30(2):143-155. Read Article
DuBose LE, Moser DJ, Harlynn E, Fiedorowicz JG, Pierce GL. Education moderates the effects of large central artery aging on cognitive performance in middle-aged and older adults. Physiol Rep. 2019 Dec;7(23):e14291. Read Article
Persons JE, Pierce GL, Fiedorowicz JG. Heliyon. Anxiety, C-reactive protein, and obesity in NHANES 1999-2004. 2019 Aug 17;5(8):e02267. Read Article
Holwerda SW, Luehrs RE, DuBose LE, Majee R, Pierce GL. Sex and age differences in the association between sympathetic outflow and central elastic artery wall thickness in humans. Am J Physiol Heart Circ Physiol. 2019 Sep 1;317(3):H552-H560. Read Article
Nair AR, Silva SD Jr, Agbor LN, Wu J, Nakagawa P, Mukohda M, Lu KT, Sandgren JA, Pierce GL, Santillan MK, Grobe JL, Sigmund CD. Endothelial PPARγ (Peroxisome Proliferator-Activated Receptor-γ) protects from angiotensin II-induced endothelial dysfunction in adult offspring born from pregnancies complicated by hypertension. Hypertension. 2019 Jul;74(1):173-183. Read Article
Birdsall JW, Schmitz SL, Abosi OJ, DuBose LE, Pierce GL, Fiedorowicz JG. Inflammatory and vascular correlates of mood change over 8 weeks. Heart Mind. 2019 Apr-Jun;3(2):47-54. Read Article
Holwerda SW, Luehrs RE, DuBose L, Collins MT, Wooldridge NA, Stroud AK, Fadel PJ, Abboud FM, Pierce GL. Elevated muscle sympathetic nerve activity contributes to central artery stiffness in young and middle-age/older adults. Hypertension. 2019 May;73(5):1025-1035. Read Article
Luehrs RE, Newell JD Jr, Comellas AP, Hoffman EA, Warner K, Croghan A, DuBose LE, Nopoulos P, Magnotta V, Arndt S, Pierce GL, Hoth KF. CT- measured Lung Air-Trapping is Associated with Higher Carotid Artery Stiffness in Individuals with Chronic Obstructive Pulmonary Disease. J Appl Physiol. 2018 Oct 11;125(6):1760-6.
DuBose LE, Boles Ponto LL, Moser DJ, Harlynn E, Reierson L, Pierce GL. Higher aortic stiffness is associated with lower global cerebrovascular reserve among older humans. Hypertension. 2018 Aug;72(2):476-482.
Sandgren JA, Deng G, Linggonegoro DW, Scroggins SM, Perschbacher KJ, Nair AR, Nishimura TE, Zhang SY, Agbor LN, Wu J, Keen HL, Naber MC, Pearson NA, Zimmerman KA, Weiss RM, Bowdler NC, Usachev YM, Santillan DA, Potthoff MJ, Pierce GL, Gibson-Corley KN, Sigmund CD, Santillan MK, Grobe JL. Arginine vasopressin infusion is sufficient to model clinical features of preeclampsia in mice. JCI Insight. 2018 Oct 4;3(19):e99403. PMCID: PMC6237463
Pierce GL. Initiating life-long aerobic exercise 4-5 days per week before or near age 50 years: is this the 'holy-grail' of preventing age-related central artery stiffness? J Physiol. 2018 Jul;596(14):2635-2636.
Holwerda SW, Holland MT, Reddy CG, Pierce GL. Femoral vascular conductance and peroneal muscle sympathetic nerve activity responses to acute epidural spinal cord stimulation in humans. Exp Physiol. 2018 Jun;103(6):905-915. doi: 10.1113/EP086945. PMCID: PMC5984152.
Holwerda SW, Luehrs RE, Gremaud AL, Wooldridge NA, Stroud AK, Fiedorowicz JG, Abboud FM, Pierce GL. Relative burst amplitude of muscle sympathetic nerve activity is an indicator of altered sympathetic outflow in chronic anxiety. J Neurophysiol. 2018 Jul 1;120(1):11-22. doi: 10.1152/jn.00064.2018. PMCID: PMC6093954
Scroggins SM, Santillan DA, Lund JM, Sandgren JA, Krotz LK, Hamilton WS, Devor EJ, Davis HA, Pierce GL, Gibson-Corley KN, Sigmund CD, Grobe JL, Santillan MK. Elevated vasopressin in pregnant mice induces T-helper subset alterations consistent with human preeclampsia. Clin Sci (Lond). 2018;132(3):419-436. doi: 10.1042/CS20171059 PMCID: PMC5947858
Sandgren JA, Linggonegoro DW, Zhang SY, Sapouckey SA, Claflin KE, Pearson NA, Leidinger MR, Pierce GL, Santillan MK, Gibson-Corley KN, Sigmund CD, Grobe JL. Angiotensin AT1A Receptors Expressed in Vasopressin-Producing Cells of the Supraoptic Nucleus Contribute to the Osmotic Control of Vasopressin. Am J Physiol Regul Integr Comp Physiol. 2018 Jan 24. e PMCID: PMC6032302
Lane-Cordova AD, Kalil GZ, Wagner CJ, Sindler AL, Fiedorowicz JG, Ajibewa T, Haynes WG, Pierce GL. Hemoglobin A1c and C-reactive protein are independently associated with blunted nocturnal blood pressure dipping in obesity-related prediabetes. Hypertens Res. 2018:41(1):33-38. doi: 10.1038/hr.2017.82. Read Article PMCID: PMC5836467
Tong B, Abosi O, Schmitz S, Myers J, Pierce GL, Fiedorowicz JG. Bipolar disorder and related mood states are not associated with endothelial function of small arteries in adults without heart disease. Gen Hosp Psychiatry 2018;51:36-40. doi: 10.1016/j.genhosppsych.2017.12.005. PMCID: PMC5869118
Pierce GL. Initiating life-long aerobic exercise 4-5 days per week before or near age 50 years: is this the 'holy-grail' of preventing age-related central artery stiffness? J Physiol. 2018 Jul;596(14):2635-2636.
Pierce GL. Aortic stiffness in aging and hypertension: prevention and treatment with habitual aerobic exercise. Curr Hypertens Rep. 2017 Oct 18;19(11):90. Review. Read Article
Rossman MJ, Kaplon RE, Hill SD, McNamara MN, Santos-Parker JR, Pierce GL, Seals DR, Donato AJ. Endothelial cell senescence with aging in healthy humans: prevention by habitual exercise and relation to vascular endothelial function. Am J Physiol Heart Circ Physiol. 2017 Nov 1;313(5):H890-H895. Epub 2017 Sep 29. PMCID: PMC5792201
Pierce GL. Mechanisms and subclinical consequences of aortic stiffness. Hypertension. 2017 Nov;70(5):848-853. Review. Read Article PMCID: PMC5826663
Casey DP, Ueda K, Wegman-Points L, Pierce GL. Muscle contraction induced arterial shear stress increases endothelial nitric oxide synthase phosphorylation in humans. Am J Physiol Heart Circ Physiol. 2017 Oct 1;313(4):H854-H859. Read Article
DuBose LE, Voss MW, Weng TB, Kent JD, Dubishar KM, Lane-Cordova AD, Sigurdsson G, Schmid P, Barlow PB, Pierce GL. Carotid β-stiffness Index is Associated with Slower Processing Speed but not Working Memory or White Matter Integrity in Healthy Middle-Aged/Older Adults. J Appl Physiol 2017;122;868-876. Read Article
Weng TB, Pierce GL, Darling WG, Falk D, Magnotta VA, Voss MW. The acute effects of aerobic exercise on the functional capacity of the human brain networks. Brain Plast 2017;2(2):171-190.
Pierce GL, Kalil GZ, Ajibewa T, Holwerda SW, Persons J, Moser DJ, Fiedorowicz JG. Anxiety independently contributes to elevated inflammation in humans with obesity. Obesity 2017;25:286-289. Read Article
Pierce GL, Pajaniappan M, DiPietro A, Darracott-Woei-A-Sack K, Kapuku GK. Abnormal central pulsatile hemodynamics in adolescents with obesity: higher aortic forward pressure wave amplitude is independently associated with greater left ventricular mass. Hypertension 2016;68:1200-1207. Read Article
Lane-Cordova AD, Witmer JR, Dubishar K, DuBose LE, Chenard CA, Siefers KJ, Myers JE, Points LJ, Pierce GL. High trans but not saturated fat beverage causes an acute reduction in postprandial vascular endothelial function but not arterial stiffness in humans.Vasc Med. 2016;21:429-436. Read Article
Muntner P, Becker RC, Calhoun D, Chen D, Cowley AW Jr, Flynn JT, Grobe JL, Kidambi S, Kotchen TA, Lackland DT, Leslie KK, Li Y, Liang M, Lloyd A, Mattson DL, Mendizabal B, Mitsnefes M, Nair A, Pierce GL, Pollock JS, Safford MM, Santillan MK, Sigmund CD, Thomas SJ, Urbina EM. Introduction to the American Heart Association's Hypertension Strategically Focused Research Network. Hypertension 2016;67:674-680. Read Article
Pierce GL, Harris SA, Seals DR, Casey DP, Barlow P, Stauss HM. Estimated aortic stiffness is independently associated with cardiac baroreflex sensitivity in humans: role of aging and habitual endurance exercise. J Hum Hypertens 2016;30:513-520. Read Article
Kalil GZ, Recober A, Hoang-Tienor A, Zimmerman MB, Haynes WG, Pierce GL. Higher augmentation index is associated with tension-type headache and migraine in middle-aged/older humans with obesity. Obesity 2016;24:865-70. Read Article
Sandgren JA, Scroggins SM, Santillan DA, Devor EJ, Gibson-Corley KN, Pierce GL, Sigmund CD, Santillan MK, Grobe JL. Vasopressin: the missing link for preeclampsia?Am J Physiol Regul Integr Comp Physiol. 2015;309:R1062-4. Read Article
Weng TB, Pierce GL, Darling WG, Voss MW. Differential effects of acute exercise on distinct aspects of executive function. Med Sci Sports Exerc. 2015;47(7):1460-9. Read Article
Montero D, Pierce GL, Stehouwer CD, Padilla J, Thijssen DH. The impact of age on vascular smooth muscle function in humans. J Hypertens 2015 Mar;33(3):445-53. Read Article
Franklin SS, Pierce GL. Cardiorespiratory fitness and the attenuation of age-related rise in blood pressure: an important role for effective primordial prevention. J Amer Coll Cardiol 2014;64:1254-1256. Read Article
Walker AE, Kaplon RE, Pierce GL, Nowlan MJ, Seals DR. Prevention of age-related endothelial dysfunction by habitual aerobic exercise in healthy humans: Possible role of nuclear factor-κB. Clin Sci 2014;127:645-654. Read Article
Pierce GL. Oral BH4: a novel remedy for age-related skin microvascular dysfunction during hyperthermia or fool’s elixir? J Appl Physiol 2013;115:951-3. Read Article
Pierce GL. Targeting vascular endothelial insulin resistance in type 2 diabetes mellitus: is protein kinase C beta the ‘bullseye’ for reducing vascular risk in diabetes? Circulation 2013; 127:16-18. Read Article
Chalouhi N, Points L, Pierce GL, Ballas Z, Jabbour P, Hasan D. Localized increase of chemokines in the lumen of human cerebral aneurysms. Stroke 2013;44:2594-97. Read Article
Pierce GL, Casey DP, Fiedorowicz JG, Seals DR, Curry TB, Barnes JN, Wilson D, Stauss HM. Aortic pulse wave velocity and reflecting distance estimation from peripheral waveforms in humans: detection of age- and exercise training-related differences. Am J Physiol Heart Circ Physiol 2013;305:H135-H142. Read Article
Pierce GL, Zhu H, Darracott K, Edet I, Bhagatwala J, Huang Y, Dong Y. Arterial stiffness and pulse pressure amplification in overweight/obese African-American adolescents: relation with higher systolic and pulse pressure. Am J Hypertens2013;26:20-26. Read Article
DeVan AE, Eskurza I, Pierce GL, Walker AE, Jablonksi KL, Kaplon RE, Seals DR. Regular aerobic exercise protects against impaired fasting glucose-associated vascular endothelial dysfunction with aging. Clin Sci 2013; 124:325-331. Read Article