Climate change is pushing Earth's temperatures to record highs, threatening human, animal, & environmental health. Sublethal heat is especially poorly understood, but it is widespread & inescapable. 

We propose the largest experimental study of the brain ever conducted, across dozens of free-living species. With novel computational tools, we will map how sub-lethal heat reshapes neural gene activity and metabolic function. 

By leveraging nature's blueprint, our framework will uncover solutions to one of the most urgent challenges of our time—ensuring human and animal health in the face of climate change.