Auto Immune Disorders

Introduction

Thrombocytopenia is defined as a platelet count below the 150 × 109/L, the 2.5th lower percentile of the normal platelet count distribution. Typically, platelet counts higher than 50 × 109/L do not lead to clinical problems unless platelet dysfunction coexists with the low count; rather, they are picked up on a routine complete blood count. Medical help is usually sought by a patient with platelet counts less than 30 × 109/L, suffering from spontaneous bruising and purpura or with continuous/relatively long-lasting bleeding from injuries and wounds. Clinically significant spontaneous bleeding does not usually occur until the platelet count is less than 10 × 109/L.

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