Publication

Jeon, H.; Lee, C. The Dual Role of A20 (TNFAIP3) in Viral Infection: A Context-Dependent Regulator of Immunity and Pathogenesis. Viruses 2025, 17, 1634. https://doi.org/10.3390/v17121634

Park, S.; Kim, M.; Jin, W.; Yeo, J.Y.; Kim, J.-H.; Seo, Y.-S.; Park, J.-M.; Kim, J.; Kim, M.-S.; Kim, D.; et al. Effects of Emissions from Heated Tobacco Products and Reference Cigarettes on Gene Expression and Mitochondrial Function in Human Lung Epithelial BEAS-2B Cells †. Antioxidants 2025, 14, 1404. https://doi.org/10.3390/antiox14121404

Kim MI and Lee C (2024) Identification of virus-rich intermediate cells as crucial players in SARS-CoV-2 infection and differentiation dynamics of human airway epithelium. Front. Microbiol. 15:1507852. doi: 10.3389/fmicb.2024.1507852 

Kim, M.I.; Lee, C. Human Coronavirus OC43 as a Low-Risk Model to Study COVID-19. Viruses 2023, 15, 578. https://doi.org/ 10.3390/v15020578

Nguyen, N.M.; Cho, J.; Lee, C. Gut Microbiota and Alzheimer’s Disease: How to Study and Apply Their Relationship. Int. J. Mol. Sci. 2023, 24, 4047. https://doi.org/ 10.3390/ijms24044047

Lee A, Sung J, Harmalkar DS, Kang H, Lee H, Lee K, Lee C.  Vinyl-Stilbene Inhibits Human Norovirus RNA Replication by Activating Heat-Shock Factor-1.  Biomolecules & Therapeutics 2022;30:64-71.  https://doi.org/10.4062/biomolther.2021.153

Khan, M.S., Lee, C. & Kim, S.G. Non-alcoholic fatty liver disease and liver secretome. Arch. Pharm. Res. 45, 938–963 (2022). https://doi.org/10.1007/s12272-022-01419-w 

Kim, M.I., et al., Identification of brevinin-1EMa-derived stapled peptides as broad-spectrum virus entry blockers. Virology, 2021. 561: p. 6-16. https://doi.org/10.1016/j.virol.2021.05.004 

Lee, H., et al., 4′-Selenonucleosides: Regio- and Stereoselective Synthesis of Novel Ribavirin and Acadesine Analogs as Anti-Hepatitis C Virus (HCV) Agents. Asian Journal of Organic Chemistry, 2021. 10(11): p. 2993-2999. https://doi.org/10.1002/ajoc.202100563 

Lee, C., Choi, W.J. Overview of COVID-19 inflammatory pathogenesis from the therapeutic perspective. Arch. Pharm. Res. 44, 99–116 (2021). https://doi.org/10.1007/s12272-020-01301-7 

Lee, C. Controversial Effects of Vitamin D and Related Genes on Viral Infections, Pathogenesis, and Treatment Outcomes. Nutrients 2020, 12, 962. https://doi.org/10.3390/nu12040962 

Lee, C. Carrageenans as Broad-Spectrum Microbicides: Current Status and Challenges. Mar. Drugs 2020, 18, 435. https://doi.org/10.3390/md18090435 

Lee, S.; Mailar, K.; Kim, M.I.; Park, M.; Kim, J.; Min, D.-H.; Heo, T.-H.; Bae, S.K.; Choi, W.; Lee, C. Plant-Derived Purification, Chemical Synthesis, and In Vitro/In Vivo Evaluation of a Resveratrol Dimer, Viniferin, as an HCV Replication Inhibitor. Viruses 2019, 11, 890. https://doi.org/10.3390/v11100890

Harmalkar, D.S., et al., Identification of novel non-nucleoside vinyl-stilbene analogs as potent norovirus replication inhibitors with a potential host-targeting mechanism. European Journal of Medicinal Chemistry, 2019. 184: p. 111733.

Lee, C. Griffithsin, a Highly Potent Broad-Spectrum Antiviral Lectin from Red Algae: From Discovery to Clinical Application. Mar. Drugs 2019, 17, 567. https://doi.org/10.3390/md17100567

Choi, M., et al., Establishment of Nrf2-deficient HaCaT and immortalized primary human foreskin keratinocytes and characterization of their responses to ROS-induced cytotoxicity. Toxicology in Vitro, 2019. 61: p. 104602.

Lee, C. CRISPR/Cas9-Based Antiviral Strategy: Current Status and the Potential Challenge. Molecules 2019, 24, 1349. https://doi.org/10.3390/molecules24071349 

Lee, H., et al., Asymmetric Synthesis of 2′-C-Methyl-4′-selenonucleosides as Anti-Hepatitis C Virus Agents. The Journal of Organic Chemistry, 2019. 84(22): p. 14414-14426. http://dx.doi.org/10.1021/acs.joc.9b01462

Lee, Choongho, Therapeutic Modulation of Virus-Induced Oxidative Stress via the Nrf2-Dependent Antioxidative Pathway, Oxidative Medicine and Cellular Longevity, 2018, 6208067, 26 pages, 2018. https://doi.org/10.1155/2018/6208067 

Kim, D.; Goo, J.-I.; Kim, M.I.; Lee, S.-J.; Choi, M.; Than, T.T.; Nguyen, P.H.; Windisch, M.P.; Lee, K.; Choi, Y.; et al. Suppression of Hepatitis C Virus Genome Replication and Particle Production by a Novel Diacylglycerol Acyltransferases Inhibitor. Molecules 2018, 23, 2083. https://doi.org/10.3390/molecules23082083 

Dong-Jin Ye, Yeo-Jung Kwon, Hyoung-Seok Baek, Sangyun Shin, Choongho Lee, Jun-Won Yun, Ki Taek Nam, Kyung-Min Lim, Young-Jin Chun, Discovery of Ezrin Expression as a Potential Biomarker for Chemically Induced Ocular Irritation Using Human Corneal Epithelium Cell Line and a Reconstructed Human Cornea-like Epithelium Model, Toxicological Sciences, Volume 165, Issue 2, October 2018, Pages 335–346, https://doi.org/10.1093/toxsci/kfy134 

Lee, S., Y.H. Chung, and C. Lee, US28, a Virally-Encoded GPCR as an Antiviral Target for Human Cytomegalovirus Infection. Biomolecules & Therapeutics, 2017. 25(1): p. 69-79.  https://doi.org/10.4062/biomolther.2016.208 

Choi, M., et al., Establishment of Immortalized Primary Human Foreskin Keratinocytes and Their Application to Toxicity Assessment and Three Dimensional Skin Culture Construction. Biomolecules & Therapeutics, 2017. 25(3): p. 296-307. https://doi.org/10.4062/biomolther.2017.043 

Lee, Choongho, Collaborative Power of Nrf2 and PPARγ Activators against Metabolic and Drug-Induced Oxidative Injury, Oxidative Medicine and Cellular Longevity, 2017, 1378175, 14 pages, 2017. https://doi.org/10.1155/2017/1378175 

Kim, J., et al., A simple and sensitive liquid chromatography–tandem mass spectrometry method for trans-ε-viniferin quantification in mouse plasma and its application to a pharmacokinetic study in mice. Journal of Pharmaceutical and Biomedical Analysis, 2017. 134: p. 116-121. http://dx.doi.org/10.1016/j.jpba.2016.11.044

Moon J-S, Lee S-H, Kim E-J, Cho H, Lee W, Kim G-W, et al. (2016) Inhibition of Hepatitis C Virus in Mice by a Small Interfering RNATargeting a Highly Conserved Sequence in Viral IRES Pseudoknot. PLoS ONE 11(1): e0146710. doi:10.1371/journal.pone.0146710

Lee, S., Yoon, K. D., Lee, M., Cho, Y., Choi, G., Jang, H., Kim, B., Jung, D. H., Oh, J. G., Kim, G. W., Oh, J. W., Jeong, Y. J., Kwon, H. J., Bae, S. K., Min, D. H., Windisch, M. P., Heo, T. H., & Lee, C. (2016). Identification of a resveratrol tetramer as a potent inhibitor of hepatitis C virus helicase. British journal of pharmacology, 173(1), 191–211. https://doi.org/10.1111/bph.13358 

2004 Role of the PDZ Domain-Binding Motif of the Oncoprotein E6 in the Pathogenesis of Human Papillomavirus Type 31

2006 Analysis of the roles of E6 binding to E6TP1 and nuclear localization in the human papillomavirus type 31 life cycle

2007 Binding Dynamics of Hepatitis C Virus ’ NS5A Amphipathic Peptide to Cell and Model Membranes

2010 A small molecule inhibits HCV replication and alters NS4B's subcellular distribution

2010 Identification of a class of HCV inhibitors directed against the nonstructural protein NS4B

2011 Discovery of Hepatitis C Virus NS5A Inhibitors as a New Class of Anti-HCV Therapy

2011 Identification of human UGT isoforms responsible for glucuronidation of efavirenz and its three hydroxy metabolites

2011 Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons

2011 Synergic Effect of Trimebutine Combined with Mosapride on Gastrointestinal Dysfunction and Visceral Pain Induced in Stress Models

2011 The hepatitis C virus NS5A inhibitor (BMS-790052) alters the subcellular localization of the NS5A non-structural viral protein

2012 Roles of phosphoinositides and phosphoinositides kinases in hepatitis C virus RNA replication

2013 A hepatitis C virus NS4B inhibitor suppresses viral genome replication by disrupting NS4B’s dimerization multimerization as well as its interaction with NS5A

2013 Daclatasvir potential role in hepatitis C

2013 Interaction of Hepatitis C Virus Core Protein with Janus Kinase Is Required for Efficient Production of Infectious Viruses

2014 Chemical genetics-based discovery of indole derivatives as HCV NS5B polymerase inhibitors

2014 Mangosteen xanthones suppress hepatitis C virus genome replication

2014 Roles of the PDZ domain-binding motif of the human papillomavirus type 16 E6 on the immortalization and differentiation of primary human foreskin keratinocytes

2015 Development and validation of a liquid chromatography with tandem mass spectrometry method for the quantification of vitisin B in rat plasma and urine

2015 Immortalization of Primary Keratinocytes and Its Application to Skin Research

2015 Indole derivatives inhibit hepatitis C virus replication through induction of pro-inflammatory cytokines

2015 Phosphatidylinositol 4,5-Bisphosphate Is an HCV NS5A Ligand and Mediates Replication of the Viral Genome

2015 Synthesis and Structure?Activity Relationship of Novel Indole Acrylamide Derivatives as HCV Replication Inhibitors