Friday
1st May, 2019
online
all times are British Summer Time, London, United Kingdom
online
all times are British Summer Time, London, United Kingdom
Session Chairs: Alessandra Gaeta & Gerome Breen
Aim: The workshop will focus on challenges and opportunities in the discovery and translation of new therapeutics for psychiatric diseases. Through an engaging session and by bringing together expertise and perspectives from charities, industry, academia and the clinic, the aim of the workshop will be to stimulate a discussion on innovative approaches to build the future drug pipeline for psychiatric diseases.
14:00–14:05 | Welcome, introduction and objectives of session
14:05–14:25 | A personal experience of the psychiatric symptoms of dementia (Emily Allen, on behalf of Alzheimer’s Research UK)
14:25–14:45 | The perspective of pharma – the key attributes of a good target (Dr John Isaac, Johnson & Johnson Innovation)
14:45–15:05 | The perspective of the academic community – key challenges in the field and opportunities (Prof. Gerome Breen, King's College London)
15:05–15:15 | Accelerating innovative drug discovery: An introduction to the Psychiatry Consortium (Dr. Laura Ajram, Psychiatry Consortium)
15:15–15:30 | Panel with Q&A
15:45–15:50 | Introduction (Dr. Laura Ajram, Psychiatry Consortium)
15:50–16:20 | Group discussions
Group 1: Pathways to drug discovery and new approaches to target identification
Group 2: Mapping the process from a genetic hit to a drug lead
Group 3: Target validation: preclinical models and translation to the clinic
16:20–16:50 | Feedback of individual group discussions (~10 minutes each)
16:50–17:00 | Wrap up and close
Session Chair: Prof. Thalia Eley & Andrew Grotzinger
17:15–17:30 | Anxiety Working Group of the Psychiatric Genomics Consortium (Prof. Thalia Eley, King's College London)
17:30–17:45 | Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (Prof. Cathryn Lewis, King's College London)
17:45–18:00 | Eating Disorders Working Group of the Psychiatric Genomics Consortium (Prof. Cynthia Bulik, UNC Chapel Hill, North Carolina & Karolinska Institutet)
18:00–18:15 | Schizophrenia Working Group of the Psychiatric Genomics Consortium (James Walter/Michael O'Donovan, Cardiff University)
18:15–18:30 | Genetic Architecture of 11 Major Psychiatric Disorders at Biobehavioral and Functional Genomic Levels (Andrew Grotzinger, The University of Texas at Austin)