†co-first author / *co-corresponding author

Publications

[26] J. Kim, E. Lee, S. Ahn, J. Lee, SeungHyun Park, W. Ryu, "Direct Ink Writing of Void-free Heterogeneous Microneedle Mesh for Dual-phase Drug Delivery.", Virtual and Physical Prototyping 20.1 (2025): e2504075.

[25] J. Yun, W. Ryu, J. Park*, SeungHyun Park*, "Methacrylated Hyaluronic Acid Microneedle-based Electrochemical Sensor for Vitamin B6 Monitoring.", Journal of Mechanical Science and Technology (2025): 1-7. (KCI, Scopus listed)

[24] S. Park, S. Y. Kim, S. Lee, SeungHyun Park, H. R. Lim, "Advanced Microfluidic-Based Wearable Electrochemical Sensors for Continuous Biochemical Monitoring.", Advanced Electronic Materials (2025): 2500010.

[23] J. Sung, S, Y. Ju, SeungHyun Park, W. K. Jung, J. Y. Je, S. J. Lee, "Lysine-Proline-Valine peptide mitigates fine dust-induced keratinocyte apoptosis and inflammation by regulating oxidative stress and modulating the MAPK/NF-κB pathway.", Tissue and Cell 95 (2025): 102837. 

[22] J. Yun†, SeungHyun Park†, N. W. Kim†, J. Kang, S. Kim, S. Hur*, W Ryu*, "K-doped Co3O4-decorated Microneedle Clip for Non-enzymatic Glucose Detection in Plant Health Monitoring.", Sensors and Actuators B: Chemical 435 (2025): 137600. (IF=8.0, JCR top 0.7%)

[21] SeungHyun Park, "Recent advances of electrochemical sensors on microneedles.", JMST Advances 6.2 (2024): 141-148. (KCI listed)

[20] J. Kim, H. Kim, SeungHyun Park, S. Y. Han, H. Hong, D. S. Yang, Y. J. Kim, J. Lee, J. H. Kim, S.-W. Cho, W. Ryu, "Individually-addressable Composite Microneedle Electrode Array by Mold-and-Place Method for Glucose Detection.", Sensors and Actuators B: Chemical 401 (2023): 134884.

[19] Y. Kang, J. Lee, SeungHyun Park, J. Kim, S. I. Kim, W. Ryu, "Balloon Catheter-Integrated Piezoelectric Micropyramid Arrays for Measuring Vascular Stiffness.", ACS Applied Materials & Interfaces 15.14 (2023): 17653-17663.

[Before PKNU]

[18] SeungHyun Park†, Y. J. Kim†, E. Kostal, V. Matylitskaya, S. Partel*, W. Ryu*, "Highly-sensitive single-step sensing of levodopa by swellable microneedle-mounted nanogap sensors.", Biosensors and Bioelectronics 220 (2023): 114912. (IF=12.5, JCR top 2.9%)

[17] Y. Kim, J. Lee, H. Hong, SeungHyun Park, W. Ryu, "Self‐Powered Wearable Micropyramid Piezoelectric Film Sensor for Real‐Time Monitoring of Blood Pressure.", Advanced Engineering Materials 25.2 (2023): 2200873.

[16] SeungHyun Park, K. Lee*, W. Ryu*. "Research progress on detachable microneedles for advanced applications.", Expert opinion on Drug Delivery 19.9 (2022): 1115-1131. (IF=8.1, JCR top 7.7%)

[15] SeungHyun Park, Y. J. Kim, S. Park, H. Hong, J. Lee, S. I. Kim, K. Lee, W. Ryu. "Rapid Extraction and Detection of Biomolecules via a Microneedle Array of Wet-Crosslinked Methacrylated Hyaluronic Acid.", Advanced Materials Technologies 7.3 (2022): 2100874. (IF=7.8, JCR top 17.9%)

[14] J. Lee, I. H. Seo, SeungHyun Park, S. I. Kim, W. Ryu, "Near-field Electrospinning of Conductive 3D Microstructure Electrode for Extraction of Photosynthetic Electrons.", Transactions of the Korean Society of Mechanical Engineers, B 46.5 (2022): 237-246.

[13] K. Lee†, SeungHyun Park†, D. H. Jo†, C. S. Cho, H. Y. Jang, J. Yi, M. Kang, J. Kim, H. Y. Jung, J. H. Kim*, W. Ryu*, A. Khademhosseini*. "Self-Plugging Microneedle (SPM) for Intravitreal Drug Delivery.", Advanced Healthcare Materials 11.12 (2022): 2102599 (Selected as a frontispiece). (IF=7.4, JCR top 7.5%)

[12] SeungHyun Park†, K. Lee†, H. Kang†, Y. Lee, J. Lee, J. H. Kim, H. B. Song*, W. Ryu*. "A single administration of a biodegradable, separable microneedle can substitute for multiple eye drops in the treatment of infectious keratitis.", Advanced Healthcare Materials 10.11 (2021): 2002287 (Selected as a back cover). (IF=7.4, JCR top 7.5%)

[11] J. Lee, E. H. Jang, J. H. Kim, SeungHyun Park, Y. Kang, S. Park, K. Lee, J. H. Kim, Y. N. Youn*, W. Ryu*. "Highly flexible and porous silk fibroin microneedle wraps for perivascular drug delivery.", Journal of Controlled Release 340 (2021): 125-135 (Selected as a front cover).

[10] K. Lee, J. Lee, S. G. Lee, SeungHyun Park, D. S. Yang, J. J. Lee, A. Khademhosseini, J. S. Kim, W. Ryu, "Microneedle drug eluting balloon for enhanced drug delivery to vascular tissue.", Journal of controlled Release 321 (2020): 174-183.

[9] Y. Lee, SeungHyun Park, S. I. Kim, K. Lee, W. Ryu, "Rapidly detachable microneedles using porous water-soluble layer for ocular drug delivery.", Advanced Materials Technologies 5.5 (2020): 1901145.

[8] K. Lee, SeungHyun Park, J. Lee, W. Ryu, "Three-step thermal drawing for rapid prototyping of highly customizable microneedles for vascular tissue insertion.", Pharmaceutics 11.3 (2019): 100.

[7] K. Lee, S. G. Lee, I. Jang, SeungHyun Park, D. Yang, I. H. Seo, S. Bong, D. H. An, M. K. Lee, I. K. Jung, Y. H. Jang, J. S. Kim*, W. Ryu*, "Linear micro-patterned drug eluting balloon (LMDEB) for enhanced endovascular drug delivery.", Scientific Reports 8 (2018): 3666.

[6] SeungHyun Park†, D. H. Jo†, C. S. Cho, K. Lee, J. H. Kim, S. Ryu, C. Joo, J. H. Kim*, W. Ryu*. "Depthwise-controlled scleral insertion of microneedles for drug delivery to the back of the eye.", European Journal of Pharmaceutics and Biopharmaceutics 133 (2018): 31-41. (IF=4.5, JCR top 10.5%)

[5] J. Lee, D. H. Kim, K. Lee, I. H. Seo, SeungHyun Park, E. H. Jang, Y. Park, Y. N. Youn*, W. Ryu*,"Transfer-molded wrappable microneedle meshes for perivascular drug delivery.", Journal of Controlled Release 268 (2017): 237-246.

[4] D. H. Kim, E. H. Jang, K. Lee, J. Lee, SeungHyun Park, I. H. Seo, K. W. Lee, S. H. Lee, W. Ryu*, Y. N. Youn*, "A biodegradable microneedle cuff for comparison of drug effects through perivascular delivery to balloon-injuries arteries.", Polymers 9.2 (2017): 56.

[3] SeungHyun Park, K. Lee, J. Lee, J. H. Yoon, D. H. Jo, J. H. Kim, K. Kang, W. Ryu, "Microneedle-based minimally-invasive measurement of puncture resistance and fracture toughness of sclera.", Acta Biomaterialia 44 (2016): 286-294. (IF=6.0)

[2] J. Lee, SeungHyun Park, I. H. Seo, K. J. Lee, W. Ryu. "Rapid and repeatable fabrication of high A/ R silk fibroin microneedles using thermally-drawn micromolds.", European Journal of Pharmaceutics and Biopharmaceutics 94 (2015): 11-19.

[1] K. Lee, SeungHyun Park, J. Lee, E. H. Jang, H. C. Joo, Y. N. Youn*, W. Ryu*. "Perivascular biodegr adable microneedle cuff for reduction of neointima formation after vascular injury.", Journal of Controlled release 192 (2014): 174-181.

Book chapter

[1] K. Lee,  SeungHyun Park, J. Lee, W. Ryu "Commercialized Microneedles," in Microneedling in Clinical Practice, 91-108, CRC Press