†co-first author / *co-corresponding author

Publications

[30] C. W. Lee†, Nankyung Kim†, SeungHyun Park*, D. S. Kim*, "Snap-Through–Driven Liquid Crystal Elastomers for High-Power Remote Microneedle Actuation toward Smart Livestock Systems .", Advanced Functional Materials accepted. (IF=19.9, JCR top 4.2%)

[29] S. Ahn, J. Kim, SeungHyun Park*, W. Ryu*, "Patterned Screen-Printing Process for Substrate-free and Scalable Hyaluronic Acid Microneedle Arrays.", Advanced Materials Technologies accepted. (IF=6.0, JCR top 30.4%)

[28] H. Kim, SeungHyun Park, J. Kim, J. Yun, S. Kim,  W. Ryu*, "Cobalt oxide based microneedle sensor for direct detection of glucose from plant leaves.", Micro & Nano Manufacturing 2.1 (2026): 9.

[27] S. Lee, Y. Boo, SeungHyun Park, S. Eom, W. Ryu, W. J. Kim*, "Pathological Nitric Oxide-Triggered Microneedle Patch for Spatiotemporally Controlled Therapy of Acute and Chronic Inflammatory Disorders.", Advanced Healthcare Materials (2026): e04714. (IF=9.6, JCR top 8.5%)

[26] J. Kim, E. Lee, S. Ahn, J. Lee, SeungHyun Park, W. Ryu*, "Direct Ink Writing of Void-free Heterogeneous Microneedle Mesh for Dual-phase Drug Delivery.", Virtual and Physical Prototyping 20.1 (2025): e2504075. (IF=10.2, JCR top 6.6%)

[25] J. Yun, W. Ryu, J. Park*, SeungHyun Park*, "Methacrylated Hyaluronic Acid Microneedle-based Electrochemical Sensor for Vitamin B6 Monitoring.", Journal of Mechanical Science and Technology 39.8 (2025): 4863-4869. (IF=1.5, JCR Q3)

[24] J. Sung, S, Y. Ju, SeungHyun Park, W. K. Jung, J. Y. Je, S. J. Lee*, "Lysine-Proline-Valine peptide mitigates fine dust-induced keratinocyte apoptosis and inflammation by regulating oxidative stress and modulating the MAPK/NF-κB pathway.", Tissue and Cell 95 (2025): 102837. (IF=2.7, JCR top 6.8%)

[23] J. Yun†, SeungHyun Park†, N. W. Kim†, J. Kang, S. Kim, S. Hur*, W Ryu*, "K-doped Co3O4-decorated Microneedle Clip for Non-enzymatic Glucose Detection in Plant Health Monitoring.", Sensors and Actuators B: Chemical 435 (2025): 137600. (IF=8.0, JCR top 0.7%)

[22] S. Park, S. Y. Kim, S. Lee, SeungHyun Park, H. R. Lim*, "Advanced Microfluidic-Based Wearable Electrochemical Sensors for Continuous Biochemical Monitoring.", Advanced Electronic Materials 11.10 (2025): 2500010. (IF=5.3, JCR Q1)

[21] SeungHyun Park*, "Recent advances of electrochemical sensors on microneedles.", JMST Advances 6.2 (2024): 141-148.

[20] J. Kim, H. Kim, SeungHyun Park, S. Y. Han, H. Hong, D. S. Yang, Y. J. Kim, J. Lee, J. H. Kim, S.-W. Cho, W. Ryu*, "Individually-addressable Composite Microneedle Electrode Array by Mold-and-Place Method for Glucose Detection.", Sensors and Actuators B: Chemical 401 (2023): 134884. (IF=8.4, JCR top 1%)

[19] Y. Kang†, J. Lee†, SeungHyun Park, J. Kim, S. I. Kim, W. Ryu*, "Balloon Catheter-Integrated Piezoelectric Micropyramid Arrays for Measuring Vascular Stiffness.", ACS Applied Materials & Interfaces 15.14 (2023): 17653-17663. (IF=10.4, JCR Q1) 

[Before PKNU]

[18] SeungHyun Park†, Y. J. Kim†, E. Kostal, V. Matylitskaya, S. Partel*, W. Ryu*, "Highly-sensitive single-step sensing of levodopa by swellable microneedle-mounted nanogap sensors.", Biosensors and Bioelectronics 220 (2023): 114912. (IF=12.5, JCR top 2.9%)

[17] Y. Kim, J. Lee, H. Hong, SeungHyun Park, W. Ryu*, "Self‐Powered Wearable Micropyramid Piezoelectric Film Sensor for Real‐Time Monitoring of Blood Pressure.", Advanced Engineering Materials 25.2 (2023): 2200873.

[16] SeungHyun Park, K. Lee*, W. Ryu*. "Research progress on detachable microneedles for advanced applications.", Expert opinion on Drug Delivery 19.9 (2022): 1115-1131. (IF=8.1, JCR top 7.7%)

[15] SeungHyun Park, Y. J. Kim, S. Park, H. Hong, J. Lee, S. I. Kim, K. Lee, W. Ryu*. "Rapid Extraction and Detection of Biomolecules via a Microneedle Array of Wet-Crosslinked Methacrylated Hyaluronic Acid.", Advanced Materials Technologies 7.3 (2022): 2100874. (IF=7.8, JCR top 17.9%)

[14] J. Lee, I. H. Seo, SeungHyun Park, S. I. Kim, W. Ryu*, "Near-field Electrospinning of Conductive 3D Microstructure Electrode for Extraction of Photosynthetic Electrons.", Transactions of the Korean Society of Mechanical Engineers, B 46.5 (2022): 237-246.

[13] K. Lee†, SeungHyun Park†, D. H. Jo†, C. S. Cho, H. Y. Jang, J. Yi, M. Kang, J. Kim, H. Y. Jung, J. H. Kim*, W. Ryu*, A. Khademhosseini*. "Self-Plugging Microneedle (SPM) for Intravitreal Drug Delivery.", Advanced Healthcare Materials 11.12 (2022): 2102599 (Selected as a frontispiece). (IF=7.4, JCR top 7.5%)

[12] SeungHyun Park†, K. Lee†, H. Kang†, Y. Lee, J. Lee, J. H. Kim, H. B. Song*, W. Ryu*. "A single administration of a biodegradable, separable microneedle can substitute for multiple eye drops in the treatment of infectious keratitis.", Advanced Healthcare Materials 10.11 (2021): 2002287 (Selected as a back cover). (IF=7.4, JCR top 7.5%)

[11] J. Lee, E. H. Jang, J. H. Kim, SeungHyun Park, Y. Kang, S. Park, K. Lee, J. H. Kim, Y. N. Youn*, W. Ryu*. "Highly flexible and porous silk fibroin microneedle wraps for perivascular drug delivery.", Journal of Controlled Release 340 (2021): 125-135 (Selected as a front cover).

[10] K. Lee, J. Lee, S. G. Lee, SeungHyun Park, D. S. Yang, J. J. Lee, A. Khademhosseini, J. S. Kim*, W. Ryu*, "Microneedle drug eluting balloon for enhanced drug delivery to vascular tissue.", Journal of controlled Release 321 (2020): 174-183.

[9] Y. Lee, SeungHyun Park, S. I. Kim, K. Lee, W. Ryu*, "Rapidly detachable microneedles using porous water-soluble layer for ocular drug delivery.", Advanced Materials Technologies 5.5 (2020): 1901145.

[8] K. Lee, SeungHyun Park, J. Lee, W. Ryu*, "Three-step thermal drawing for rapid prototyping of highly customizable microneedles for vascular tissue insertion.", Pharmaceutics 11.3 (2019): 100.

[7] K. Lee, S. G. Lee, I. Jang, SeungHyun Park, D. Yang, I. H. Seo, S. Bong, D. H. An, M. K. Lee, I. K. Jung, Y. H. Jang, J. S. Kim*, W. Ryu*, "Linear micro-patterned drug eluting balloon (LMDEB) for enhanced endovascular drug delivery.", Scientific Reports 8 (2018): 3666.

[6] SeungHyun Park†, D. H. Jo†, C. S. Cho, K. Lee, J. H. Kim, S. Ryu, C. Joo, J. H. Kim*, W. Ryu*. "Depthwise-controlled scleral insertion of microneedles for drug delivery to the back of the eye.", European Journal of Pharmaceutics and Biopharmaceutics 133 (2018): 31-41. (IF=4.5, JCR top 10.5%)

[5] J. Lee, D. H. Kim, K. Lee, I. H. Seo, SeungHyun Park, E. H. Jang, Y. Park, Y. N. Youn*, W. Ryu*,"Transfer-molded wrappable microneedle meshes for perivascular drug delivery.", Journal of Controlled Release 268 (2017): 237-246.

[4] D. H. Kim, E. H. Jang, K. Lee, J. Lee, SeungHyun Park, I. H. Seo, K. W. Lee, S. H. Lee, W. Ryu*, Y. N. Youn*, "A biodegradable microneedle cuff for comparison of drug effects through perivascular delivery to balloon-injuries arteries.", Polymers 9.2 (2017): 56.

[3] SeungHyun Park, K. Lee, J. Lee, J. H. Yoon, D. H. Jo, J. H. Kim, K. Kang, W. Ryu*, "Microneedle-based minimally-invasive measurement of puncture resistance and fracture toughness of sclera.", Acta Biomaterialia 44 (2016): 286-294. (IF=6.0)

[2] J. Lee, SeungHyun Park, I. H. Seo, K. J. Lee, W. Ryu*. "Rapid and repeatable fabrication of high A/ R silk fibroin microneedles using thermally-drawn micromolds.", European Journal of Pharmaceutics and Biopharmaceutics 94 (2015): 11-19.

[1] K. Lee, SeungHyun Park, J. Lee, E. H. Jang, H. C. Joo, Y. N. Youn*, W. Ryu*. "Perivascular biodegr adable microneedle cuff for reduction of neointima formation after vascular injury.", Journal of Controlled release 192 (2014): 174-181.

Book chapter

[1] K. Lee,  SeungHyun Park, J. Lee, W. Ryu "Commercialized Microneedles," in Microneedling in Clinical Practice, 91-108, CRC Press