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As a biophysicist, my research focuses on understanding how physical forces influence cellular processes and development. I combine experimental techniques, such as laser microsurgery, microscopy, and quantitative analysis, to investigate the mechanical properties of biological systems. Early in my career, I explored the dynamics of cell division, specifically the behavior of the mitotic spindle during DNA segregation. My work led to the discovery of a previously unknown mechanical connection within the spindle, resulting in multiple first-author publications.

Currently, I am studying the vertebrate notochord in zebrafish, a critical structure in spine formation, to uncover its mechanical properties and role in development. By examining how the notochord responds to genetic and physical perturbations, I aim to contribute to a deeper understanding of developmental disorders such as scoliosis. My interdisciplinary approach bridges physics, cell biology, and genetics, providing insights that could influence bio-inspired materials and tissue engineering. Through this work, I strive to unravel the fundamental biophysical principles that govern life at the cellular and organismal levels.

Get in touch at: parsa.zareiesfandabadi@duke.edu