Conformational landscape of cyclodextrin oligomers
Cyclodextrins (CDs) are used to create a wide range of supramolecular architectures. However, predicting their assemblies and identifying the possible conformers in CD oligomers have always remained challenging due to their dynamic nature. Our aim is to probe the conformer space of isolated CD oligomers by ion mobility mass spectrometry and understand the energetics associated with the conformational changes.
Supramolecular chemistry of nanoclusters
We investigate supramolecular interactions of atomically precise nanoclusters that occur at different length scales. This includes formation of host-guest complexes, precision hybrids with other nanomaterials and crystallization of cluster assemblies.
Isotopic exchange in nanoscale materials
We investigate rapid solution-state atom exchange dynamics in nanoscale materials using isotope-exchange reactions. We primarily use high resolution electrospray ionization to explore such phenomenon.
Gas-phase chemistry of metal clusters
We investigate noble metal clusters in the gas-phase. Electrospray ionization is used to transfer the ions from solution to gas-phase and characterized by mass spectrometry. Our aim is to understand the cluster structure and gas-phase stability by techniques like collision-induced dissociation.