Cp*Co(III)-Catalyzed C-H Functionalizations

First-row transition metals are available abundantly in Earth’s crust, compared to their 4d and 5d analogs. Despite their high natural abundance and low toxicity, first-row transition metals are underutilized in C-H activation. Our group is involved in the development of novel organic transformations using Cp*Co(III)-catalysis. 

In recent years, the area of mild C−H activation has gained significant importance, as it allows to carry out the reactions at or below room temperature and in the absence of any oxidant or reductant. This results in the enhancement of the functional group tolerance of the reactions and ultimately leads to the application in the late-stage functionalization of complex biomolecules. Our group is focusing on the development of mild C−H activation using Cp*Ir(III) catalysis especially using α-diazocarbonyl compounds for the synthesis of various biologically important heterocyclic scaffolds.

Total Synthesis of Natural Products

Our group is also interested in the total synthesis of indolizidinone types of natural products and their analogous using C−H functionalization strategy.

Photoredox Catalysis and Electrocatalysis

We are also interested in the development of C−H functionalization by merging it with photo-redox catalysis and electrochemistry.