Embedded Files
2026
Stereoselective construction of cyclic quaternary stereocenters by Prins cyclization with ketones
Stereoselective construction of cyclic quaternary stereocenters by Prins cyclization with ketones
Laura F. Peña, Lucía G. Parte, Carlos Díez-Poza, Asunción Barbero
Multicomponent Hosomi-Sakurai Reaction on Isosorbide Derivatives
Multicomponent Hosomi-Sakurai Reaction on Isosorbide Derivatives
Luca Banfi, Lucia Garcia de la Parte, Chiara Lambruschini, Lisa Moni, Daniel Rufo Perez, Renata Riva
Recent advances in the synthesis of fused and bridge oxacycles via Prins cyclization
Recent advances in the synthesis of fused and bridge oxacycles via Prins cyclization
Ruth Pecker, Eva Sandonís, Lucas Fraile-González, Ignacio E. Tobal, Asunción Barbero
Mannich reaction with organozinc reagents in continuous flow. experimental and computational studies
Mannich reaction with organozinc reagents in continuous flow. experimental and computational studies
Lucas Fraile-González, Ángel Sánchez-González, Laura F. Peña, Enol López
Application of the Prins reaction in oxacyclic chemistry: Recent trends
Application of the Prins reaction in oxacyclic chemistry: Recent trends
Paula González-Andrés, Laura F. Peña, Carlos Díez-Poza, Asunción Barbero
Advances in Heterocyclic Chemistry, 2026, Vol. 148, Academic Press, pp 159-214, ISBN 9780443415715
2025
Homogeneous catalysis in continuous flow. Metal and organo-catalysis
Homogeneous catalysis in continuous flow. Metal and organo-catalysis
Lucía G. Parte, Laura F. Peña, Carlos Díez-Poza, Javier Guerra, Enol López
Advances in Catalysis, 2025, Vol. 76, Academic Press, pp 33-70, ISBN 9780443429798
Homogeneous catalysis in continuous flow integrating photocatalysis, electrocatalysis, and automation technologies
Homogeneous catalysis in continuous flow integrating photocatalysis, electrocatalysis, and automation technologies
Laura F. Peña, Lucía G. Parte, Carlos Díez-Poza, Javier Guerra, Enol López.
Exploration of Structure-Property Relationships by Altering Glycol Backbone Unsaturation (Double/Triple Bonds) in Furan-Based Polyesters
Exploration of Structure-Property Relationships by Altering Glycol Backbone Unsaturation (Double/Triple Bonds) in Furan-Based Polyesters
Virginia Arnáiz, Lucía Pedraza, Carlos Díez-Poza, Mercedes Santiago-Calvo, Enol López, Asunción Barbero
Expanding the silyl-Prins toolbox: selective access to C4-quaternary stereocenters in tetrahydropyrans using internal cyclopropylsilyl alcohols
Expanding the silyl-Prins toolbox: selective access to C4-quaternary stereocenters in tetrahydropyrans using internal cyclopropylsilyl alcohols
Paula González-Andrés, Alberto Cherubin, Asunción Barbero
Organosilicon molecules bind to the instrinsically disordered protein NUPR1 by clamping its hot-spots
Organosilicon molecules bind to the instrinsically disordered protein NUPR1 by clamping its hot-spots
Laura F. Peña, Matías Estaras, Paula González-Andrés, Carlos Díez-Poza, Bruno Rizzuti, Olga Abian, Adrian Velazquez-Campoy, Juan L. Iovanna, Patricia Santofimia-Castaño, José L. Neira, Asunción Barbero
Insight into the Key Factors that Influence the Reaction Pathways in the Silyl-Prins Cyclization of gem-Vinylsilyl Alcohols
Insight into the Key Factors that Influence the Reaction Pathways in the Silyl-Prins Cyclization of gem-Vinylsilyl Alcohols
Paula González-Andrés, Carlos Díez-Poza, Laura F. Peña, Daniel González-Pinardo, Israel Fernández, Asunción Barbero
2024
Terminal Cyclopropylsilyl Alcohols as Useful Key Units to Access 2,3,4,6-Tetrasubstituted Tetrahydropyran Scaffolds by Stereocontrolled Prins Cyclization
Terminal Cyclopropylsilyl Alcohols as Useful Key Units to Access 2,3,4,6-Tetrasubstituted Tetrahydropyran Scaffolds by Stereocontrolled Prins Cyclization
Laura F. Peña, Asunción Barbero
Transition-Metal-Catalyzed Transformations for the Synthesis of Marine Drugs
Transition-Metal-Catalyzed Transformations for the Synthesis of Marine Drugs
Lucía G. Parte, Sergio Fernández, Eva Sandonís, Javier Guerra, Enol López
Stereoselective Synthesis of Polysubstituted Tetrahydropyrans by Brønsted Acid-Mediated Hydroxyalkoxylation of Silylated Alkenols
Stereoselective Synthesis of Polysubstituted Tetrahydropyrans by Brønsted Acid-Mediated Hydroxyalkoxylation of Silylated Alkenols
Carlos Díez-Poza, Patricia Val, Enol López, Asunción Barbero
Current Status of Indole-Derived Marine Natural Products: Synthetic Approaches and Therapeutic Applications
Current Status of Indole-Derived Marine Natural Products: Synthetic Approaches and Therapeutic Applications
Sergio Fernández, Virginia Arnáiz, Daniel Rufo, Yolanda Arroyo
Towards an efficient methodology for the synthesis of functionalized dihydropyrans by silyl-Prins cyclization: access to truncated natural products
Towards an efficient methodology for the synthesis of functionalized dihydropyrans by silyl-Prins cyclization: access to truncated natural products
Laura F. Peña, Paula González-Andrés, Asunción Barbero
2023
Continuous Flow Chemistry: A Novel Technology for the Synthesis of Marine Drugs
Continuous Flow Chemistry: A Novel Technology for the Synthesis of Marine Drugs
Laura F. Peña, Paula González-Andrés, Lucia G. Parte, Raúl Escribano, Javier Guerra, Asunción Barbero, Enol López
Therapeutic Potential of Heterocyclic Compounds Trageting Mitochondrial Calcium Homeostasis and Signaling in Alzheimer's Disease and Parkinson's Disease
Therapeutic Potential of Heterocyclic Compounds Trageting Mitochondrial Calcium Homeostasis and Signaling in Alzheimer's Disease and Parkinson's Disease
Victor Tapias, Paula González-Andrés, Laura F. Peña, Asunción Barbero, Lucía Núñez, Carlos Villalobos
Changing the reaction Pathway of Silyl-Prins Cyclization by Switching the Lewis Acid: Application to the Synthesis of an Antinociceptive Compound
Changing the reaction Pathway of Silyl-Prins Cyclization by Switching the Lewis Acid: Application to the Synthesis of an Antinociceptive Compound
Carlos Díez-Poza, Laura Fernández-Peña, Paula González-Andrés, Asunción Barbero
Diastereoselective Synthesis of cis-2,6-disubstituted Dihydropyrane Derivatives Through a Competitive Silyl-Prins Cyclizatrion versus Alternative Reaction Pathways
Diastereoselective Synthesis of cis-2,6-disubstituted Dihydropyrane Derivatives Through a Competitive Silyl-Prins Cyclizatrion versus Alternative Reaction Pathways
Laura F. Peña, Enol López, Ángel Sánchez-González, Asunción Barbero
Recent Advances in Biologically Active Coumarins from Marine Sources: Synthesis and Evaluation
Recent Advances in Biologically Active Coumarins from Marine Sources: Synthesis and Evaluation
Laura Fernández-Peña, Maria João Matos, Enol López
2022
The Tetrahydrofuran Motif in Marine Lipids and Terpenes
The Tetrahydrofuran Motif in Marine Lipids and Terpenes
Paula González-Andrés, Laura Fernández-Peña, Carlos Díez-Poza, Asunción Barbero
The Tetrahydrofuran Motif in Polyketide Marine Drugs
The Tetrahydrofuran Motif in Polyketide Marine Drugs
Laura Fernández-Peña, Carlos Díez-Poza, Paula González-Andrés, Asunción Barbero
Bicyclic 5-6 Systems: Four Heteroatoms 3:1
Bicyclic 5-6 Systems: Four Heteroatoms 3:1
Carlos Díez-Poza, Héctor Barbero, Laura Fernández-Peña, Asunción Barbero
2021
Influence of the Substituents on the Opening of Silylepoxy Alcohols: 5-exo-Cyclization towards Tetrahydrofurans vs. Unexpected Side Reacion Leading to Tetrahydropyrans
Influence of the Substituents on the Opening of Silylepoxy Alcohols: 5-exo-Cyclization towards Tetrahydrofurans vs. Unexpected Side Reacion Leading to Tetrahydropyrans
Carlos Díez-Poza, Asunción Barbero
Unexpected Domino Silyl-Prins/Aryl Migration Process from Geminal Vinylsilyl Alcohols
Unexpected Domino Silyl-Prins/Aryl Migration Process from Geminal Vinylsilyl Alcohols
Carlos Díez-Poza, Asunción Barbero
Marine Heterocyclic Compounds That Modulate Intracellular Calcium Signals: Chemistry and Synthesis Approaches
Marine Heterocyclic Compounds That Modulate Intracellular Calcium Signals: Chemistry and Synthesis Approaches
Paula González-Andrés, Laura Fernández-Peña, Carlos Díez-Poza, Carlos Villalobos, Lucía Núñez, Asunción Barbero
Intramolecular Cyclization of Alkenyl Alcohols. Towards the Synthesis of Oxacycles
Intramolecular Cyclization of Alkenyl Alcohols. Towards the Synthesis of Oxacycles
Paula González-Andrés, Carlos díez-Poza, Laura Fernández-Peña, Alberto Cherubin, Yolanda Blanco, Asunción Barbero
2020
Organosilanes in the synthesis of saturated heterocycles
Organosilanes in the synthesis of saturated heterocycles
Carlos díez-Poza, Laura Fernández-Peña, Alberto Cherubin, Juan Lión-Villar, Asunción Barbero
Carlos díez-Poza, Laura Fernández-Peña, Alberto Cherubin, Juan Lión-Villar, Asunción Barbero
2018
The silyl-Prins reaction as an emerging method for synthesis of heterocycles
The silyl-Prins reaction as an emerging method for synthesis of heterocycles
Carlos Díez-Poza, Héctor Barbero, Alberto Diez-Varga, Asunción Barbero
Carlos Díez-Poza, Héctor Barbero, Alberto Diez-Varga, Asunción Barbero
Synthesis of polysusbstituted tetrahydropyrans by stereoselective hydroalkoxylation of silyl alkenols: en route to tetrahydropyranyl marine analogs
Synthesis of polysusbstituted tetrahydropyrans by stereoselective hydroalkoxylation of silyl alkenols: en route to tetrahydropyranyl marine analogs
Carlos Díez-Poza, Patricia Val, Francisco J. Pulido, Asunción Barbero
Carlos Díez-Poza, Patricia Val, Francisco J. Pulido, Asunción Barbero
2017
The oxepane motif in marine drugs
The oxepane motif in marine drugs
Héctor Barbero, Carlos Díez-Poza, Asunción Barbero.
Héctor Barbero, Carlos Díez-Poza, Asunción Barbero.
Modular De novo Synthesis of Unsimmetrical BODIPY Dyes Possessing Four Different Aryl Substituents
Modular De novo Synthesis of Unsimmetrical BODIPY Dyes Possessing Four Different Aryl Substituents
Natalie Netz, Carlos Díez-Poza, Asunción Barbero, Till Opatz
Natalie Netz, Carlos Díez-Poza, Asunción Barbero, Till Opatz
Synthesis of O- and N-heterocycles by silyl-Prins Cyclization of Allylsilanes
Synthesis of O- and N-heterocycles by silyl-Prins Cyclization of Allylsilanes
Carlos Díez-Poza, Asunción Barbero
Carlos Díez-Poza, Asunción Barbero
2016
Synthesis of Azepane Derivatives by Silyl-aza-Prins Cyclization of Allylsilyl Amines: Influence of the Catalyst in the Outcome of the Reaction
Synthesis of Azepane Derivatives by Silyl-aza-Prins Cyclization of Allylsilyl Amines: Influence of the Catalyst in the Outcome of the Reaction
Asunción Barbero, Alberto Diez-Varga, Francisco J. Pulido, Alfonso González-Ortega
Asunción Barbero, Alberto Diez-Varga, Francisco J. Pulido, Alfonso González-Ortega
From Silylated Trishomoallylic Alcohols to Dioxaspirouncedecanes or Oxocanes: Catalyst and Substitution Influence
From Silylated Trishomoallylic Alcohols to Dioxaspirouncedecanes or Oxocanes: Catalyst and Substitution Influence
Asunción Barbero, Alberto Diez-Varga, Manuel Herrero, Francisco J. Pulido
Asunción Barbero, Alberto Diez-Varga, Manuel Herrero, Francisco J. Pulido
2015
Efficient access to polysubstituted tetrahydrofurans by electrophilic cyclization of vinylsilyl alcohols
Efficient access to polysubstituted tetrahydrofurans by electrophilic cyclization of vinylsilyl alcohols
Asunción Barbero, Héctor Barbero, Alfonso González-Ortega, Francisco J. Pulido, Patricia Val, Alberto Diez-Varga, Joaquín R. Morán
Asunción Barbero, Héctor Barbero, Alfonso González-Ortega, Francisco J. Pulido, Patricia Val, Alberto Diez-Varga, Joaquín R. Morán
2014
Competitive Silyl-Prins Cyclization versus Tandem Sakurai-Prins Cyclization: An Interesting Substitution Effect
Competitive Silyl-Prins Cyclization versus Tandem Sakurai-Prins Cyclization: An Interesting Substitution Effect
Alberto Diez-Varga, Héctor Babero, Francisco J. Pulido, Alfonso González-Ortega, Asunción Barbero
Alberto Diez-Varga, Héctor Babero, Francisco J. Pulido, Alfonso González-Ortega, Asunción Barbero
2013
Multicomponent Prins Cyclization from Allylsilyl Alcohols Leading to Dioxaspirodecanes
Multicomponent Prins Cyclization from Allylsilyl Alcohols Leading to Dioxaspirodecanes
Francisco J. Pulido, Alberto Diez-Varga, Asunción Barbero
Francisco J. Pulido, Alberto Diez-Varga, Asunción Barbero
2012
Efficiency of Acid- and Mercury-Catalyzed Cyclization Reactions in the Synthesis of Tetrahydrofurans from Allylsilyl Alcohols
Efficiency of Acid- and Mercury-Catalyzed Cyclization Reactions in the Synthesis of Tetrahydrofurans from Allylsilyl Alcohols
Francisco J. Pulido, Asunción Barbero, Patricia Val., Alberto Diez, Alfonso González-Ortega
Francisco J. Pulido, Asunción Barbero, Patricia Val., Alberto Diez, Alfonso González-Ortega
2011
One-pot multicoupling reaction of silylcopper reagents, organolithium compounds and α,β-unsaturated nitriles
One-pot multicoupling reaction of silylcopper reagents, organolithium compounds and α,β-unsaturated nitriles
Francisco J. Pulido, Asunción Barbero, Yolanda Blanco
Francisco J. Pulido, Asunción Barbero, Yolanda Blanco
Seven-Membered Ring Formation from Cyclopropanated Oxo- and Epoxyallylsilanes
Seven-Membered Ring Formation from Cyclopropanated Oxo- and Epoxyallylsilanes
Francisco J. Pulido, Asunción Barbero, Pilar Castreño
Francisco J. Pulido, Asunción Barbero, Pilar Castreño
2010
Synthesis of 3-Methylenecyclohexan-1-ols by Lewis Acid Catalyzed Cyclication of Epoxy-allylsilanes
Synthesis of 3-Methylenecyclohexan-1-ols by Lewis Acid Catalyzed Cyclication of Epoxy-allylsilanes
Francisco J. Pulido, Asunción Barbero, Pilar Castreño
Francisco J. Pulido, Asunción Barbero, Pilar Castreño
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