Publications

Cancino, S., Cabeza-Bratesco D., Matamala, E., York J.M., Zavala, K., Montecinos, C., Bustamante-Villarreal, S., Maldonado, R., Riadi, G., Brauchi, S.E. & Opazo, J.C. An Evolutionary Novelty in TRPV1 Functional Regulation: Characterization of a Dominant-Negative Isoform Exclusive to Catarrhine Primates. bioRxiv. 2025. 

Merello Oyarzún, G, Olivares-Costa., M, Basile, L., Pástor, T., Mendoza-Soto, P., Padilla-Santiago, L., Mardones, G.A., Binda, C. &  & Opazo, J.C. Evolutionary and Functional Analysis of Monoamine Oxidase F: A Novel Member of the Monoamine Oxidase Gene Family. Genome Biology and Evolution. 2025. Link

Opazo, J.C. & Riadi, G. Physical Trait Variation in Hass Avocados Across Different Fruit Sizes. EcoEvoRxiv 2024. Link

Uribe, C., Nery, M.F., Zavala, K., Mardones, G.A., Riadi, G. & Opazo, J.C. Evolution of ion channels in cetaceans: A natural experiment in the tree of life. Scientific Reports. 2024. Link

Storz, J.F., Quiroga-Carmona, M., Liphardt, S., Bautista, N.M., Opazo, J.C., Rico Cernhorska, A., Salazar-Bravo, J.,  Good, J.M. & D’Elía, G. Extreme high-elevation mammal surveys reveal unexpectedly high upper range limits of Andean mice. The American Naturalist. 2024. Link

Olivares-Costa., M, Merello Oyarzún, G., Verbel-Vergara, D. González, M.P., Arancibia, D., Andrés, M.E. & Opazo, J.C. Evolution of Lysine-Specific Demethylase 1 and REST Corepressor gene families and their molecular interaction. Communications Biology. 2023. Link

Martínez, D., Nualart, D., Loncoman, C., Opazo, J.C., Zavala, K., Morera, F.J., Mardones, G.A. & Vargas-Chacoff, L. Discovery of BbX Transcription Factor in the Patagonian Blennie: Exploring Expression Changes Following Combined Bacterial and Thermal Stress Exposure. Developmental & Comparative Immunology. 2023. Link

Storz, J.F., Liphardt, s., Quiroga-Carmona, M., Bautista, N.M., Opazo, J.C., Wheeler, T.B., D’Elía, G. & Good, J.M. Genomic insights into the mystery of mouse mummies on the summits of Atacama volcanoes. Current Biology. 2023. Link

Opazo, J.C., Vandewege, M.W., Hoffmann, F.G., Zavala, K., Melendez, C., Luchsinger, C., Cavieres, V.A., Vargas-Chacoff, L., Morera, F.J., Burgos, P.V., Tapia-Rojas, C. & Mardones, G.A. How many sirtuin genes are out there? evolution of sirtuin genes in vertebrates with a description of a new family member. Molecular Biology and Evolution. 2023. Link

Cabezas-Bratesco, D., McGee, F.A., Colenso, C.K., Zavala, K., Granata, D., Carnevale, V., Opazo, J.C. & Brauchi, S.E. Sequence and structural conservation reveal fingerprint residues in TRP channels. eLife. 2022. Link

Opazo, J.C., Zavala, K., Vargas-Chacoff, L., Morera, F.J., Mardones, G.A. Identification of multiple TAR DNA Binding Protein retropseudogene lineages during the evolution of primates. Scientific Reports. 2022. 12: 3823. Link

Opazo, J.C., Hoffmann, F.G., Zavala, K. & Edwards, S. Evolution of the DAN gene family in vertebrates. Developmental Biology. 2022. 482: 34-43. Link

Gutierrez, J., Platt II, R.N., Opazo, J.C., Ray, D.A., Hoffmann, F.G., Vandewege, M.W. Evolutionary history of the vertebrate Piwi gene family. PeerJ. 2021. 9: e12451 Link

Hoffmann, F.G., Storz, J.F., Kuraku, S., Vandewege, M.W. & Opazo J.C. Whole genome duplications and the diversification of the Globin-X genes of vertebrates. Genome Biology and Evolution. 2021. 13: 10. Link

Opazo, J.C., Vandewege, M.W., Gutierrez, J., Zavala, K., Vargas-Chacoff, L., Morera, F.J., Mardones, G.A. Independent duplications of the Golgi phosphoprotein 3 oncogene in birds. Scientific Reports. 2021. 11: 12483. Link

Tejada Martinez, D., de Magalhaes, J.P. & Opazo, J.C. Positive selection and fast turnover rate in tumor suppressor genes reveal how cetaceans resist cancer. Proceedings of the Royal Society B. 2021. 288: 20202592. Link

Prothmann, A., Hoffmann, F.G., Opazo, J.C., Herbener, P., Storz, J.F., Burmester, T. & Hankeln, T. The globin gene family in arthropods: Evolution and functional diversity. Frontiers in Genetics. 2020. 11:858. Link

Storz, J.F., Quiroga-Carmona, M., Opazo, J.C., Bowen, T., Farson, M., Steppan, S. & D'Elia, G. Discovery of the world's highest-dwelling mammal. Proceedings of the National Academy of Sciences USA. 2020. 117: 18169-18171. Link

Flores-Aldama, L., Vandewege, M.W., Zavala, K., Colenso, C.K., Bustos, D., Gonzalez, W., Brauchi, S.E. & Opazo, J.C. Evolutionary analyses reveal independent origins of gene repertoires and structural motifs associated to fast inactivation in calcium-selective TRPV channels. Scientific Reports. 2020. 10: 8684. Link

Teta, P., D Elia, G., Opazo, J.C. Integrative taxonomy of the southernmost tucu-tucus in the world: differentiation of the nominal forms associated with Ctenomys magellanicus Bennett, 1836 (Rodentia, Hystricomorpha, Ctenomyidae). Mammalian Biology. 2020. 100: 125-139. Link

Opazo, J.C., Kuraku, S., Zavala, K., Toloza-Villalobos, J. & Hoffmann, FG. Evolution of Nodal and Nodal-related genes and the putative composition of the heterodimers that trigger the Nodal pathway in vertebrates. Evolution & Development. 2019. 1-13. Link

Figueroa, R.J., Reig, G., Stanic, K., Wichmann, I.A., Opazo, J.C., Owen, G.I., Corvalan, A.H., Concha, M.L. & Amigo, J.D. The reprimo gene family member, reprimo-like (rprml), is required for blood development in embryionic zebrafish. Scientific Reports. 2019. 9:7131. Link

D Elia, G., Jaksic, F., Bacigalupe, L.D., Bozinovic, F., Canto, J.L., Correa, C.C., Fonturbel, F.E., Lison, F., Mendez, M.A., Nespolo, R., Opazo, J.C., Palma, E., Rau, J.R., Rodriguez, S.M., Rodriguez-Serrano, E., Sabat, P., Vasquez, R.A. Victoriano, P. Sugerencias para mejorar la regulacion chilena de manipulacion de vertebrados terrestres en poblaciones naturales en el contexto de investigaciones cientificas. Gayana. 2019. 83: 63-67. Link

Opazo, J.C. & Zavala, K. Phylogenetic evidence for independent origins of GDF1 and GDF3 genes in anurans and mammals. Scientific Reports. 2018. 8:13595. Link

Giorello, F., Feijoo, M., D Elia, G., Naya, D., Valdez, L., Opazo, J.C. & Lessa, E. An association between differential expression and genetic divergence in the patagonian olive mouse (Abrothrix olivacea). Molecular Ecology. 2018. 1-13. Link

Amigo, JD., Opazo, J.C., Jorquera, R., Wichmann, IA., Garcia-Bloj, B., Alarcon, MA., Owen, GI., Corvalan, AH. The reprimo gene family: a novel tumor suppressor gene lineage in gastric cancer. International Journal of Molecular Sciences. 2018. 19: 1862. Link

Opazo, J.C., Zavala, K., Miranda-Rottmann, A. & Araya, R. Evolution of dopamine receptors: Phylogenetic evidence suggests a later origin of the DRD2l and DRD4rs dopamine receptor gene lineages. PeerJ. 2018. 6:e4593. Link

Stanic, K., Quiroz, A., Lemus, C.G., Wichmann, I.A., Corvalan, A.H., Owen, G.I., Opazo, J.C., Concha, M.L. & Amigo, J.D. Expression of RPRM/rprm in the olfactory system of embryonic Zebrafish (Danio rerio). Frontiers in Neuroanatomy. 2018. 12:23. Link

Hoffmann, F.G., Vandewege, M.W., Storz, J.F. & Opazo, J.C. Gene turnover and diversification of the alpha and beta globin gene families of sauropsid vertebrates. Genome Biology and Evolution. 2018. 10: 344-358. Link

Malone, L., Opazo, J.C., Ryan, P.L. & Hoffmann, F.G. Progressive erosion of the relaxin1 gene in bovids. General and Comparative Endocrinology. 2017. 252: 12-17. Link

Cespedes, H.A., Zavala, K. Vandewege, M.W. & Opazo, J.C. Evolution of the alpha2 adrenoreceptors in vertebrates: ADRA2D is absent in mammals and crocodiles. General and Comparative Endocrinology. 2017. 250: 85-94. Link

Figueroa, R., Carrasco-Avino, G., Wichmann, I.A., Lange, M., Owen, G.I., Siekmann, A.F., Corvalan, A.H., Opazo, J.C. & Amigo, J.D. Reprimo tissue-specific expression pattern is conserved between zebrafish and human. PLoS One. 2017. 12(5): e0178274. Link

Zavala, K., Vandewege, M.W., Hoffmann, F.G. & Opazo, J.C. Evolution of the beta-adrenoreceptors in vertebrates. General and Comparative Endocrinology. 2017. 240: 129-137. Link

Opazo, J.C., Zavala, K., Krall, P. & Arias, R.A. Evolution of gremlin 2 in cetartiodactyl mammals: genes loss coincides with lack of upper jaw incisors in ruminants. PeerJ. 2017. 5:e2901.

Wichmann, I.A., Zavala, K., Hoffmann, F.G., Vandewege, M.W., Corvalan, A.H., Amigo, J.D., Owen, G.I. & Opazo, J.C. Evolutionary history of the reprimo tumor suppressor gene family in vertebrates with a description of a new reprimo gene lineage. Gene. 2016. 591: 145-254.

Zavala, K. & Opazo, J.C. Lineage-specific expansion of the chalcone synthase gene family in rosids. PLoS One. 2015. 10(7): e0133400.

Opazo, J.C., Lee, A.L., Hoffmann, F.G., Toloza-Villalobos, J., Burmester, T., Venkatesh, B. & Storz, J.F. Ancient duplications and expression divergence in the globin gene superfamily of vertebrates: Insights from the elephant shark genome and transcriptome. Molecular Biology and Evolution. 2015. 32: 1684-1694.

Valdez, L., Giorello, F., Feijoo, M., Opazo, J.C., Lessa, E.P., Naya, D. & D Elia, G. Characterization of the kidney transcriptome of the long-haired mouse Abrothrix hirta (Rodentia, Sigmodontinae) and comparison to renal expression profile in the closely-related A. Olivacea. PLoS One. 2015. 10(4): e0121148.

Opazo, J.C., Hoffmann, F.G., Natarajan, C., Witt, C.C., Berenbrink, M. & Storz, J.F. Gene turnover in the avian globin gene families and evolutionary changes in hemoglobin isoform expression. Molecular Biology and Evolution. 2015. 32: 871-887.

Toloza-Villalobos, J., Arroyo, J.I. & Opazo, J.C. The circadian clock of teleost fish: a comparative analysis reveals distinct fates for duplicated genes. Journal of Molecular Evolution. 2015. 80: 57-64.

Green, R.E., Braun, E.L., Armstrong, J., Vandewege, M.W., St John, J.A., Capella-Gutierrez, S., Castoe, T.A., Kern, C., Fujita, M.K., Opazo, J.C., Jurka, J., Kojima, K.K., Caballero, J., Smit, A., Platt, R.N., Lavoie, C.A., Ramakodi, M Isberg, S.R., Miles, L., Chong, A.Y., Jaratlerdsiri, W., Gongora, J., Moran, C., Iriarte, A., Faircloth, B.C., McCormack, J., Burgess, S.C., Edwards, S.V., Janes, D.E:, Lyons, E., Williams, C., Breen, M., Gresham, C.R., Peterson, D.G., Pollock, D.D., Zhang, G., Irie, N., Jarvis, E.D., Schmidt, C.J., McCarthy, F.M., Hoffmann, F.G., Glenn, T.C:, Gabaldon, T., Patton, B., Ray, D.A. The genomes of three crocodilians provide insight into Archosaur evolution. Science. 2014. 346:

Nery, M.F. Arroyo, J.I. & Opazo, J.C. Increased rate of keratin gene loss in the cetacean lineage. BMC Genomics. 2014. 15:869.

Zhang, G., Li, C., Li, Q., Li, B., Larkin, D.M., Lee, C., Storz, J.F., Antunes, A., Meredith, R.W., Odeen, A., Cui, J., Zhou, Q., Xu, L., Pan, H., Wang, Z., Jin, L., Zhang, P., Hu, H., Yang, W., Hu, J., Xiao, J., Yang, Z., Liu, Y., Xie, Q., Lian, J., Wen, P., Zhang, F., Li, H., Zeng, Y., Xiong, Z., Liu, S., Zhou, L., Huang, Z., An, N., Wang, J., Zheng, Q., Xiong, Y., Wang, G., Wang, B., Wang, J., Fang, Y., Fonseca, R., Alfaro-Nunez, A., Schubert, M., Orlando, L., Mourier, T., Howard, J., Ganapathy, G., Smith, J., Farre, M., Narayan, J., Slavov, G., Romanov, M.N., Borges, R., Machado, J.P., Khan, I., Springer, M.S., Gatesy, J., Hoffmann, F.G., Opazo, J.C., Hastad, O., Greenwold, M.J., Sawyer, R.H., Kim, H., Kim, K.W., Li, N., Huang, Y., Bruford, M.W., Zhan, X., Dixon, A., Bertelsen, M., Derryberry, E., Warren, W., Li, S., Ray, D.A., Green, R.E., O Brien, S.J., Griffin, D., Johnson, W.E., Haussler, D., Ryder, O.A., Willerslev, E., Graves, G., Alstrom, P., Fjeldsa, J., Mindell, D., Edwards, S.V., Braun, E.L., Rahbek, C., Burt, D.W., Houde, P., Zhang, Y., Yang, H., Wang, J., Jarvis, E.D., Gilbert, M.T.P., Wang, J., & Avian Genome Consortium. Comparative genomics reveals insights into avian genome evolution and adaptation. Science. 2014. 346:1311-1320.

Lessa, E.P., Cook, J.A., D'Elia, G., Opazo, J.C. Rodent diversity in South America: transitioning into the genomics era. Frontiers in Ecology and Evolution. 2014. 2:39

Giorello, F.M., Feijoo, M., D'Elia, G., Valdez, L., Opazo, J.C., Varas, V., Naya, D.E., Lessa, E.P. Characterization of the kidney transcriptome of the South American olive mouse Abrothrix olivacea. BMC Genomics. 2014. 15:446.

Arroyo, J.I., Hoffmann, F.G. & Opazo, J.C. Evolution of the relaxin/insulin-like gene family in anthropoid primates. Genome Biology and Evolution. 2014. 6: 491-499.

Nery, M.F. Arroyo, J.I. & Opazo, J.C. Genomic organization and differential signature of positive selection in the alpha and beta globin gene clusters in two cetacean species. Genome Biology and Evolution. 2013. 5: 2359-2367.

Gaitan-Espitia, J.D., Nespolo, R.F. Opazo J.C. The complete mitochondrial genome of the land snail Cornu aspersum (Helicidae: Mollusca): intra-specific divergence of protein-coding genes and phylogenetic considerations within Euthyneura. PLoS One. 2013. 8(6):e67299

Nery, M.F. Arroyo, J.I. & Opazo, J.C. Accelerated evolutionary rate of the myoglobin gene in long-diving whales. Journal of Molecular Evolution. 2013. 76: 380-387.

Opazo, J.C., Butts, G.T., Nery, M.F., Storz, J.F. & Hoffmann, F.G. Whole-genome duplication and the functional diversification of teleost fish hemoglobins. Molecular Biology and Evolution. 2013. 30: 140-153.

Nery, M.F., Gonzalez, D.J. & Opazo, J.C. How to make a dolphin: molecular signature of positive selection in cetacean genome. PLoS One. 2013. 8(6):e65491.

Storz, J.F., Opazo, J.C. & Hoffmann, F.G. Gene duplication, genome duplication, and the functional diversification of vertebrate globins. Molecular Phylogenetics and Evolution. 2013. 66: 469-478.

Arroyo, J.I., Hoffmann, F.G. Good, S. & Opazo, J.C. INSL4 pseudogenes help define the relaxin family repertoire in the common ancestor of placental mammals. Journal of Molecular Evolution. 2012. 75: 73-78.

Barnett, A.A, Pinto, L.P., Bicca-Marques, J.C., Ferrari, S.F., Gordo, M., Guedes, P.G., Lopes, M.A., Opazo, J.C., Port-Carvalho, M., Rodrigues dos Santos, R., Soares, R.F., Spironello, W.R., Veiga, L.M., Martins Vieira, T. & Boyle, S.A. A proposal for the common names for species of Chiropotes (Pitheciinae: Primates). Zootaxa. 2012. 3507: 79-83.

Nery, M.F., Gonzalez, D.J., Hoffmann, F.G. & Opazo, J.C. Resolution of the laurasiatherian phylogeny: evidence from genomic data. Molecular Phylogenetics and Evolution. 2012. 64: 685-689.

Hoffmann, F.G., Opazo, J.C., Hoogewijs, D., Hankeln, T., Ebner, B., Vinogradov, S. & Storz, J.F. Evolution of the globin gene family in deuterostomes: Lineage-specific patterns of diversification and attrition. Molecular Biology and Evolution. 2012. 29: 1735-1745.

Arroyo, J.I., Hoffmann, F.G. & Opazo, J.C. Gene turnover and differential retention in the relaxin/insulin-like gene family in primates. Molecular Phylogenetics and Evolution. 2012. 63: 768-776. Selected by Global Medical Discovery.

Arroyo, J.I., Hoffmann, F.G. & Opazo, J.C. Gene duplication and positive selection explains unusual physiological roles of the relaxin gene in the European rabbit. Journal of Molecular Evolution. 2012. 74: 52-60.

Hoffmann, F.G., Opazo, J.C. & Storz, J.F. Whole-genome duplications spurred the functional diversification of the globin gene superfamily in vertebrates. Molecular Biology and Evolution. 2012. 29: 303-312. Selected by Faculty of 1000.

Pierron, D., Opazo, J.C., Heiske, M., Papper, Z., Uddin, M., Chand, G., Wildman, D.E., Romero, R., Goodman, M. & Grossman, L.I. Silencing, positive selection and parallel evolution: busy history of primate cytochromes c. PLoS One. 2011. 6(10): e26269.

Nespolo, R.F., Bacigalupe, L.D., Figueroa, C.C. Koteja, P. & Opazo, J.C. Using new tools to solve an old problem: the evolution of endothermy in vertebrates. Trends in Ecology and Evolution. 2011. 26: 414-423.

Hoffmann, F.G., Opazo, J.C. & Storz, J.F. Differential Loss and Retention of Cytoglobin, Myoglobin, and Globin-E during the Radiation of Vertebrates. Genome Biology and Evolution. 2011. 3: 588-600.

Hoffmann, F.G. & Opazo, J.C. Evolution of the relaxin/insulin-like gene family in placental mammals: implications for its early evolution. Journal of Molecular Evolution. 2011. 72: 72-79.

Storz, J.F., Opazo, J.C. & Hoffmann, F.G. Phylogenetic diversification of the globin gene superfamily in chordates. IUBMB Life. 2011. 63: 313-322.

Storz, J.F., Hoffmann, F.G., Opazo, J.C., Sanger, T.J. & Moriyama, H. Developmental regulation of hemoglobin synthesis in the green anole lizard, Anolis carolinensis. Journal of Experimental Biology. 2011. 214: 575-581.

Hoffmann, F.G., Storz, J.F., Gorr, T.A. & Opazo, J.C. Lineage-specific patterns of functional diversification in the alpha- and beta-globin gene families of tetrapod vertebrates. Molecular Biology and Evolution. 2010. 27: 1126-1138.

Hoffmann, F.G., Opazo, J.C. & Storz, J.F. Gene co-option and convergent evolution of oxygen-transport hemoglobins in jawed and jawless vertebrates. Proceedings of the National Academy of Sciences USA. 2010. 107: 14274-14279. Selected by Faculty of 1000.

Gering, E.J., Opazo, J.C. & Storz, J.F. Molecular evolution of cytochrome b in high- and low-altitude deer mice (genus Peromyscus). Heredity. 2009. 102: 226-235.

Opazo, J.C., Sloan, A.M., Campbell, K.L. & Storz, J.F. Origin and Ascendancy of a Chimeric Fusion Gene: the beta/delta-Globin Gene of Paenungulate Mammals. Molecular Biology and Evolution. 2009. 26: 1469-1478.

Wildman, D.E., Jameson, N.M., Opazo, J.C. & Yi, S.V. A fully resolved genus level phylogeny of neotropical primates (Platyrrhini). Molecular Phylogenetics and Evolution. 2009. 53: 694-702.

Uddin, M., Opazo, J.C., Wildman, D.E., Sherwood, C.C., Hof, P.R., Goodman, M. & Grossman, L.I. Molecular evolution of the cytochrome c oxidase subunit VA gene in primates. BMC Evolutionary Biology. 2008. 8:8.

Opazo, J.C., Hoffmann, F.G. & Storz, J.F. Genomic evidence for independent origins of beta like globin genes in monotremes and therian mammals. Proceedings of the National Academy of Sciences USA. 2008. 105: 1590-1595.

Uddin, M., Goodman, M., Erez, O., Romero, R., Liu, G., Islam, M., Opazo, J.C., Sherwood, C.C., Grossman, L.I. & Wildman, D.E. Distinct genomic signatures of adaptation in pre- and post-natal environments during human evolution. Proceedings of the National Academy of Sciences USA. 2008. 105: 3215-3220.

Hoffmann, F.G., Opazo, J.C. & Storz, J.F. Rapid rates of lineage-specific gene duplications and deletion in the alpha-globin gene family. Molecular Biology and Evolution. 2008. 25: 591-602.

Chen, C., Opazo, J.C., Erez, O., Uddin, M., Santolaya-Forgas, J., Goodman, M., Grossman, L.I., Romero, R. & Wildman, D.E. The human progesterone receptor shows evidence of adaptive evolution associated with its ability to act as a transcription factor. Molecular Phylogenetics and Evolution. 2008. 47: 637-649.

Storz, J.F., Hoffmann, F.G., Opazo, J.C. & Moriyama, H. Adaptive functional divergence among triplicated alpha-globin genes in rodents. Genetics. 2008. 178: 1623-1638.

Opazo, J.C., Bugueno, M., Carter, M.J., Palma, R.E. & Bozinovic, F. Phylogeography of the subterranean rodent Spalacopus cyanus (Caviomorpha, Octodontidae). Journal of Mammalogy. 2008. 89: 837-844.

Opazo, J.C., Hoffmann, F.G. & Storz, J.F. Differential loss of embryonic globin genes during the radiation of placental mammals. Proceedings of the National Academy of Sciences USA. 2008. 105: 12950-12955.

Hoffmann, F.G., Opazo, J.C. & Storz, J.F. New Genes Originated via Multiple Pathways in the beta-Globin Gene Family of Rodents. Molecular Biology and Evolution. 2008. 25: 2589-2600.

Wildman, D.E., Uddin, M., Opazo, J.C., Liu, G., Lefort, V., Gascuel, O., Grossman, L.I., Romero, R. & Goodman, M. Genomics, biogeography, and the diversification of placental mammals. Proceedings of the National Academy of Sciences USA. 2007. 104: 14395-14400.

Storz, J.F., Baze, M., Waite, J.L., Hoffmann, F.G., Opazo, J.C. & Hayes, J.P. Complex signatures of selection and gene conversion in the duplicated globin genes of house mice. Genetics. 2007. 177: 481-500.

Opazo, J.C., Wildman, D.E., Prychitko, T., Johnson, R.M. & Goodman, M. Phylogenetic relationships and divergence times among New World Monkeys (Platyrrhini, Primates). Molecular Phylogenetics and Evolution. 2006. 40: 274-280.

Opazo, J.C., Palma, R.E., Melo, F. & Lessa, E.P. Adaptive evolution of the insulin gene in caviomorph rodents. Molecular Biology and Evolution. 2005. 22: 1290-1298.

Schmidt, T.R., Wildman, D.E., Uddin, M., Opazo, J.C., Goodman, M. & Grossman, L.I. Rapid electrostatic evolution at the binding site for cytochrome c on cytochrome c oxidase in anthropoid primates. Proceedings of the National Academy of Sciences USA. 2005. 102: 6379-6384.

Opazo, J.C. A Molecular timescale for caviomorph rodents (Mammalia, Hystricognathi). Molecular Phylogenetics and Evolution. 2005. 37: 932-937.

Opazo, J.C., Soto-Gamboa, M. & Fernandez, M.J. Cell size and basal metabolic rate in hummingbirds. Revista Chilena de Historia Natural. 2005. 78: 261-265.

Opazo J.C., Soto-Gamboa M. & Bozinovic F. Blood glucose concentration in caviomorph rodents. Comparative Biochemistry and Physiology. 2004. 137A: 57-64.

Bacigalupe L.D., Nespolo R.F., Opazo J.C. & Bozinovic F. Phenotypic flexibility in a novel thermal environment: Phylogenetic inertia in thermogenic capacity and evolutionary adaptation in organ size. Physiological and Biochemical Zoology. 2004. 77: 805-815.

Nespolo R.F., Opazo J.C. & Bozinovic F. Thermal acclimation and non-shivering thermogenesis in three species of south american of rodents: A comparison between arid and mesic habitats. Journal of Arid Environments. 2001. 48: 581-590.

Opazo J.C., Nespolo R.F. & Bozinovic F. Arousal from Torpor in the Chilean mouse-opposum (Thylamys elegans): Does nonshivering thermogenesis play a role? Comparative Biochemistry and Physiology. 1999. 123A: 393-397.

Nespolo R.F., Opazo J.C., Rosenmann M. & Bozinovic F. Thermal acclimation, maximum metabolic rate and nonshivering thermogenesis in Phyllotys xanthopygus (Rodentia) inhabiting the andean range. Journal of Mammalogy. 1999. 80: 742-748.