Publications
Replication stress underlies genomic instability at CTCF/cohesin-binding sites in cancer
Faseela EE, Notani D, Sabarinathan R.
Preprint, bioRxiv, 2023.
Singh AK, Walavalkar K, Tavernari D, Ciriello G, Notani D, Sabarinathan R.
Molecular Oncology, 2023.
[GitHub Source code]
Kumar R, Dhaka B, Sahoo S, Jolly MK, Sabarinathan R.
Molecular Oncology, 17: 1041-1059, 2023
[GitHub Source code]
[News article @IndiaBioscience]
Differential chromatin accessibility landscape of gain-of-function mutant p53 tumours
Dhaka B, Sabarinathan R.
BMC Cancer, 21:669, 2021. [GitHub Source code]
Gupta A, Sabarinathan R, Bala P, Donipadi V, Vashisht D, Katika MR, Kandakatla M, Mitra D, Dalal A, Bashyam MD.
Journal of General Virology, 102:001562, 2021.
Exome sequencing identifies ARID2 as a novel tumor suppressor in early-onset sporadic rectal cancer
Bala P, Singh AK, Kavadipula P, Kotapalli V, Sabarinathan R, Bashyam MD.
Oncogene, 40:863-874, 2021.
Variable interplay of UV-induced DNA damage and repair at transcription factor binding sites
Frigola J, Sabarinathan R, Gonzalez-Perez A, Lopez-Bigas N.
Nucleic Acids Research, 49:891-901, 2021.
Walavalkar K, Saravanan B, Singh AK, Jayani RS, Nair A, Farooq U, Islam Z, Soota D, Mann R, Shivaprasad PV, Freedman ML, Sabarinathan R, Haiman CA, Notani D.
Nature Communications 11, 1-14, 2020.
Local Determinants of the Mutational Landscape of the Human Genome
Gonzalez-Perez A, Sabarinathan R, Lopez-Bigas N.
Cell, 177:101-114, 2019. (Review article)
Twist1 induces chromosomal instability (CIN) in colorectal cancer cells
Khot M, Sreekumar D, Jahagirdar S, Kulkarni A, Hari K, Faseela EE, Sabarinathan R, Jolly MK, Sengupta K.
Human Molecular Genetics, 29:1673-1688, 2020.
Contributions to PCAWG Consortium
Pan-cancer analysis of whole genomes
The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium
Nature 578, 82-93, 2020.
[Lead "Panorama of driver mutations in cancer" study]
The repertoire of mutational signatures in human cancer
Alexandrov LB, Kim J, Haradhvala NJ, Huang MN, Ng AWT, Wu Y, Boot A, Covington KR, Gordenin DA, Bergstrom EN, Islam SMA, Lopez-Bigas N, Klimczak LJ, McPherson JR, Morganella S, Sabarinathan R, Wheeler DA, Mustonen V, Getz G, Rozen SG, Stratton MR.
Nature 578, 94–101, 2020.
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
Rheinbay E, Nielsen MM, Abascal F, Wala JA, Shapira O, Tiao G, Hornshøj H, Hess JM, Juul RI, Lin Z, Feuerbach L, Sabarinathan R, Madsen T, Kim J, Mularoni L, et al.,
Nature 578, 102–111, 2020.
2013 - 2018
Pich O, Muiños F, Sabarinathan R, Reyes-Salazar I, Gonzalez-Perez A, Lopez-Bigas N.
Cell, 175:1074-1087, 2018.
Sabarinathan R, Anthon C, Gorodkin J, Seemann S.
Genes, 9:604, 2018.
Tamborero D, Rubio-Perez C, Muiños F, Sabarinathan R, Piulats JM, Muntasell A, Dienstmann R, Lopez-Bigas N, Gonzalez-Perez A.
Clinical Cancer Research, 24:3717-3728, 2018.
Frigola J, Sabarinathan R, Mularoni L, Muiños F, Gonzalez-Perez A, Lopez-Bigas N.
Nature Genetics, 49:1684-1692, 2017. [Source code]
Hayward NK, Wilmott JS, Waddell N, Johansson PA, et al.,
Nature, 545:175-180, 2017.
Mularoni L, Sabarinathan R, Deu-Pons J, Gonzalez-Perez A, Lopez-Bigas N.
Genome Biology, 17:128, 2016. [Software]
Sabarinathan R, Mularoni L, Deu-Pons J, Gonzalez-Perez A, Lopez-Bigas N.
Nature, 532:264-267, 2016. [Source code]
Stewart JB, Alaei-Mahabadi B, Sabarinathan R, Samuelsson R, Gorodkin J, Gustafsson CM, Larsson E.
PLoS Genetics, 11:e1005333, 2015.
Birkedal U, Christensen‐Dalsgaard M, Krogh N, Sabarinathan R, Gorodkin J, Nielsen H.
Angewandte Chemie, 127:461-465, 2015.
Sabarinathan R, Wenzel A, Novotny P, Tang X, Kalari KR, Gorodkin J.
PLOS ONE, 1:e82699, 2014.
Sabarinathan R, Tafer H, Seemann SE, Hofacker IL, Stadler PF, Gorodkin J.
Nucleic Acids Research, 41:W475-W479, 2013. [Webserver]
Sabarinathan R, Tafer H, Seemann SE, Hofacker IL, Stadler PF, Gorodkin J.
Human Mutation, 34:546-556, 2013. [Software]