Images obtained from optical instruments results from a convolution between the intensity distribution of the observed object with the optical response of the system, the PSF. Consequently, in order to measure the astrophysical metrics of interest (astrometry, photometry, velocity, topology, ...), one must usually have a model or priors on the PSF.

For instance, the estimation of astrometry and photometry on images of globular clusters is degraded in the presence of strong sources confusion due to noise and crowding, and having an accurate model of the PSF allows to improve the source disentanglement. Also, in order to obtain highly resolved images, one must use deconvolution algorithms that are designed to suppress the PSF contribution to unveil the real intensity distribution of the object.

Adaptive-optics (AO) instruments enable diffraction-limited observations but introduce complex features in the PSF that are not well represented with classical models (Gaussian, Moffat, ...). Furthermore, AO introduce strong PSF variability across time, which prevents to offset the telescope to accurately calibrate the PSF from the image of a bright star. Moreover, AO come with spatial variability of the PSF due to anisoplanatism or tomography. Figure 3 illustrates on simulations of galactic center observations that not accounting for this variability can significantly degrade the photometry accuracy [Beltramo-Martin et al., AO4ELT6, 2019].