North America Oligonucleotide Synthesis Market Opportunities, Regional Forecast To 2027

The North America Oligonucleotide Synthesis market is expected to reach US$ $ 1,541.03 Mn in 2027 from US$ 609.90 Mn in 2018. The market is estimated to grow with a CAGR of 11.2% from 2019-2027.

The North America Oligonucleotide Synthesis market is poised for substantial growth, fueled by increasing investments in pharmaceutical and biotechnology companies, supportive government funding, and a growing number of market players focusing on this area.

North America Oligonucleotide Synthesis market , short single-stranded DNA sequences, serve as sequence-specific binding agents crucial for identifying target DNA. Their versatility extends across disease diagnosis, biotechnology research, therapeutics, forensics, and drug discovery. Notably, they play a significant role in diagnosing human genetic diseases, enabling the detection of single base pair changes like the one responsible for sickle cell anemia. Labeled oligonucleotide probes can distinguish between normal and mutant gene alleles under stringent hybridization conditions.

Beyond diagnostics, researchers are harnessing oligonucleotides to develop more efficient and sustainable chemical synthesis methods. By assembling these short sequences into longer fragments encoding synthetic genes, they can program bacteria or yeast cells to produce specific enzymes.

Furthermore, oligonucleotides are revolutionizing therapeutics by offering the ability to target, manipulate, silence, or modulate malfunctioning genes. Companies like Ionis Pharmaceuticals are at the forefront of this innovation, particularly in developing antisense oligonucleotide (ASO) therapies. This broad and promising potential across diverse fields is a significant driver for North America Oligonucleotide Synthesis market expansion.

Recent clinical trials, such as the phase 3 trial in Canada investigating RG6042 for Huntington's disease, further underscore the growing importance of oligonucleotide therapeutics. RG6042, an antisense oligonucleotide developed by Ionis Pharmaceuticals and acquired by Roche, aims to target and degrade the mutant huntingtin protein, the primary cause of Huntington's disease. This multi-site trial across Canadian provinces highlights the active research and development landscape in the region.

Within North America, the United States is projected to be the leading market. This dominance is attributed to increasing investments and dedicated funding directed towards manufacturing companies, academic institutions, and research institutes engaged in developing gene synthesis-based products, including precision medicine and other advanced therapeutics. Consequently, the confluence of these factors positions the US to contribute the largest share to the North American oligonucleotide synthesis market during the forecast period.

North America Oligonucleotide Synthesis – Market Segmentation

North America Oligonucleotide Synthesis Market By Product

• Synthesized Oligonucleotides

  • Primers

  • Probes

  • Large-Scale Synthesis

  • Others

• Reagents

  • Equipment

North America Oligonucleotide Synthesis market By Application

• Research

• Diagnostics

• Therapeutics

North America Oligonucleotide Synthesis market By End User

• Academic Research Institutes

• Pharmaceutical & Biotechnology Companies

• Diagnostic Laboratories

• Other End Users

North America Oligonucleotide Synthesis market By Geography

• North America

  • US

  • Canada

  • Mexico

North America Oligonucleotide Synthesis market Company Profiles

• Thermo Fisher Scientific Inc.

• GenScript

• Molecular Assemblies

• Twist Biosciences

• Evonetix

• DNA Script

• Nuclera Nucleics

• Camena Bioscience

• Synthomics

• Ansa Biotechnologies

North America Oligonucleotide Synthesis market Strategic Insights

Strategic insights for the North America Oligonucleotide Synthesis market provides data-driven analysis of the industry landscape, including current trends, key players, and regional nuances. These insights offer actionable recommendations, enabling readers to differentiate themselves from competitors by identifying untapped segments or developing unique value propositions. Leveraging data analytics, these insights help industry players anticipate the market shifts, whether investors, manufacturers, or other stakeholders. A future-oriented perspective is essential, helping stakeholders anticipate market shifts and position themselves for long-term success in this dynamic region. Ultimately, effective strategic insights empower readers to make informed decisions that drive profitability and achieve their business objectives within the market.

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Author’s Bio:

Suryakant Gadekar

Senior Market Research Expert at Business Market Insights