PUBLICATIONS

2025

• Assessment of gelatin-epigallocatechin gallate nanoparticles with hyaluronic acid coating for treating dry eye associated keratopathy in rats
  Chan, M. H., Tseng, C. L., Huang, W. H. & Lin, C. T., 2025, In: Journal of Veterinary Medical Science. 87, 4, p. 364-376 13 p.

• Development of iron oxide based-upconversion nanocomposites for cancer therapeutics treatment
  Dash, P., Thirumurugan, S., Chen, Y. L., Dhawan, U., Lin, Y. C., Lin, C. P., Liu, W. C., Tseng, C. L. & Chung, R. J., Apr 30 2025, In: International Journal of Pharmaceutics. 675, 125545.

• Exploration of 3D Few-Shot Learning Techniques for Classification of Knee Joint Injuries on MR Images
  Dang, V. H., Nguyen, M. T., Le, N. H., Nguyen, T. P., Tran, Q. V., Mai, T. H., Vy, V. P. T., Hung, T. N. K., Lee, C. Y., Tseng, C. L., Le, N. Q. K. & Nguyen, P. A., Jul 2025, In: Diagnostics. 15, 14, 1808.

• Intranasal delivery of epigallocatechin gallate-laden platelet extracellular vesicles for mitigating retinal glaucoma
  Pan, W. Y., Weng, P. W., Wu, S. H., Hsiao, C. H., Jheng, P. R., Nguyen, H. N. T., Tseng, C. L., Burnouf, T., Rethi, L., Nguyen, H. T., Huang, W. Y., Wang, T. J. & Chuang, A. E. Y., May 10 2025, In: Journal of Controlled Release. 381, 113596.

• Optimization of the poloxamer 407-conjugated gelatin to synthesize pH-sensitive nanocarriers for controlled paclitaxel delivery
  Ly, H. Q., Chen, Y. J., Nguyen, V. T. & Tseng, C. L., Feb 2025, In: Journal of Polymer Research. 32, 2, 38.

• Platelet-derived extracellular vesicle drug delivery system loaded with kaempferol for treating corneal neovascularization
  Liu, G. S., Chen, H. A., Chang, C. Y., Chen, Y. J., Wu, Y. Y., Widhibrata, A., Yang, Y. H., Hsieh, E. H., Delila, L., Lin, I. C., Burnouf, T. & Tseng, C. L., Aug 2025, In: Biomaterials. 319, 123205.

• Therapeutic Assessment of Diverse Doxycycline-Based Formulations in Promoting Deep Corneal Wound Healing: Evidence from a Rat Model
  Chan, S. M., Tseng, C. L., Huang, W. H. & Lin, C. T., Feb 2025, In: Veterinary Sciences. 12, 2, 143.
  Open Access

2024

• Assessment of cardiac adverse events following COVID-19 vaccination by speckle tracking echocardiography
  Chaichuum, S., Tseng, C. L., Chang, S. C., Chan, C. L., Hsu, C. Y., Chiang, E., Daimon, M., Chiang, S. J. & Chen, H. H., Dec 2024, In: Scientific Reports. 14, 1, 10849.

• Construction of Methotrexate-Loaded Bi2S3 Coated with Fe/Mn-Bimetallic Doped ZIF-8 Nanocomposites for Cancer Treatment Through the Synergistic Effects of Photothermal/Chemodynamic/Chemotherapy
  Dash, P., Nataraj, N., Panda, P. K., Tseng, C. L., Lin, Y. C., Sakthivel, R. & Chung, R. J., 2024, (Accepted/In press) In: ACS Applied Materials and Interfaces.

• Corrigendum to “Development and functional evaluation of a hyaluronic acid coated nano-formulation with kaempferol as a novel intra-articular agent for knee osteoarthritis treatment”[ Biomed. Pharmacother. 175(2024) 116717] (Biomedicine & Pharmacotherapy (2024) 175, (S0753332224006012), (10.1016/j.biopha.2024.116717))
  Lee, C. Y., Chang, Y. C., Yang, K. C., Lin, Y. F., Wu, A. T. H. & Tseng, C. L., Aug 2024, In: Biomedicine and Pharmacotherapy. 177, 116944.

• Development and functional evaluation of a hyaluronic acid coated nano-formulation with kaempferol as a novel intra-articular agent for Knee Osteoarthritis treatment
  Lee, C. Y., Chang, Y. C., Yang, K. C., Lin, Y. F., Wu, A. T. H. & Tseng, C. L., Jun 2024, In: Biomedicine and Pharmacotherapy. 175, 116717.

• Enhancing wound healing and adhesion through dopamine-assisted gelatin-silica hybrid dressings
  Lin, Y. C., Wang, H. Y., Tang, Y. C., Lin, W. R., Tseng, C. L., Hu, C. C. & Chung, R. J., Feb 2024, In: International Journal of Biological Macromolecules. 258, 128845.

• Injectable cross-linked hyaluronic acid hydrogels with epigallocatechin gallate loading as vitreous substitutes
  Chen, H. A., Tai, Y. N., Hsieh, E. H., Thacker, M., Lin, I. C., Tseng, C. L. & Lin, F. H., Aug 2024, In: International Journal of Biological Macromolecules. 275, 133467.

• NIR-Responsive Methotrexate-Modified Iron Selenide Nanorods for Synergistic Magnetic Hyperthermic, Photothermal, and Chemodynamic Therapy
  Thirumurugan, S., Muthiah, K. S., Lin, Y. C., Dhawan, U., Liu, W. C., Wang, A. N., Liu, X., Hsiao, M., Tseng, C. L. & Chung, R. J., May 22 2024, In: ACS Applied Materials and Interfaces. 16, 20, p. 25622-25636 15 p.

• Zwitterionic modified and freeze-thaw reinforced foldable hydrogel as intraocular lens for posterior capsule opacification prevention
  Yang, C. J., Huang, W. L., Yang, Y., Kuan, C. H., Tseng, C. L. & Wang, T. W., Sept 2024, In: Biomaterials. 309, 122593.

2023

• Deep Learning Prediction Model for Patient Survival Outcomes in Palliative Care Using Actigraphy Data and Clinical Information
  Huang, Y., Roy, N., Dhar, E., Upadhyay, U., Kabir, M. A., Uddin, M., Tseng, C. L. & Syed-Abdul, S., Apr 2023, In: Cancers. 15, 8, 2232.

• Dry eye syndrome model established in rabbits via mitomycin C injection in the lacrimal gland
  Lin, I.-C., Wang, Y.-C., Chen, Y.-Z., Tang, Y.-J., Chen, K.-H. & Tseng, C.-L., Jan 2023, In: Taiwan Journal of Ophthalmology.

• Enhancing paracellular and transcellular permeability using nanotechnological approaches for the treatment of brain and retinal diseases
  Khalil, A., Barras, A., Boukherroub, R., Tseng, C. L., Devos, D., Burnouf, T., Neuhaus, W. & Szunerits, S., 2023, (Accepted/In press) In: Nanoscale Horizons. 9, 1, p. 14-43 30 p. 

• Expanding applications of allogeneic platelets, platelet lysates, and platelet extracellular vesicles in cell therapy, regenerative medicine, and targeted drug delivery
  Burnouf, T., Chou, M.-L., Lundy, D. J., Chuang, E.-Y., Tseng, C.-L. & Goubran, H., Dec 2023, In: J. Biomed. Sci.. 30, 1, 79. 

• Functional Peptide-Loaded Gelatin Nanoparticles as Eyedrops for Cornea Neovascularization Treatment
  Chu, Y. C., Fang, H. W., Wu, Y. Y., Tang, Y. J., Hsieh, E. H., She, Y., Chang, C. Y., Lin, I. C., Chen, Y. J., Liu, G. S. & Tseng, C. L., 2023, In: International Journal of Nanomedicine. 18, p. 1413-1431 19 p.

• Inhibition of microRNA-328 Increases Ocular Mucin Expression and Conjunctival Goblet Cells
  Choo, J., Liao, C. H., Tseng, C. L., Chen, J. L., Cheng, H. C., Liang, C. L. & Juo, S. H. H., Feb 2023, In: Biomedicines. 11, 2, 287.
  Research output: Contribution to journal › Article › peer-review

• Recent Developments in Mitochondrial G‐Quadruplex Recognising Fluorescent Probes: A Review
  Kumar, P., Pandith, A., Tseng, C. L. & Burnouf, T., Aug 2023, In: Journal of Photochemistry and Photobiology C: Photochemistry Reviews. 56, 100619.
  Research output: Contribution to journal › Review article › peer-review

• Synthesis of Methotrexate-Loaded Dumbbell-Shaped Titanium Dioxide/Gold Nanorods Coated with Mesoporous Silica and Decorated with Upconversion Nanoparticles for Near-Infrared-Driven Trimodal Cancer Treatment
  Dash, P., Thirumurugan, S., Tseng, C. L., Lin, Y. C., Chen, S. L., Dhawan, U. & Chung, R. J., Jul 19 2023, In: ACS Applied Materials and Interfaces. 15, 28, p. 33335-33347 13 p.

• TAK1 blockade as a therapy for retinal neovascularization
  Wang, J. H., Lin, F. L., Chen, J., Zhu, L., Chuang, Y. F., Tu, L., Ma, C., Ling, D., Hewitt, A. W., Tseng, C. L., Shah, M. H., Bui, B. V., van Wijngaarden, P., Dusting, G. J., Wang, P. Y. & Liu, G. S., Jan 2023, In: Pharmacological Research. 187, 106617.

• Theranostic doxorubicin encapsulated FeAu alloy@metal-organic framework nanostructures enable magnetic hyperthermia and medical imaging in oral carcinoma
  Dhawan, U., Tseng, C. L., Wu, P. H., Liao, M. Y., Wang, H. Y., Wu, K. C. W. & Chung, R. J., Feb 2023, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 48, 102652.

2022

• A Sandwich-Type Electrochemical Immunosensor for Insulin Detection Based on Au-Adhered Cu5Zn8 Hollow Porous Carbon Nanocubes and AuNP Deposited Nitrogen-Doped Holey Graphene
  Sakthivel, R., Prasanna, S. B., Tseng, C. L., Lin, L. Y., Duann, Y. F., He, J. H. & Chung, R. J., Sept 2022, In: Small. 18, 35, 2202516.

• Binary colloidal crystals (BCCs) modulate the retina-related gene expression of hBMSCs – A preliminary study
  Chen, Y. J., Chang, R., Fan, Y. J., Yang, K. C., Wang, P. Y. & Tseng, C. L., Oct 2022, In: Colloids and Surfaces B: Biointerfaces. 218, 112717.

• Evaluation of Topical and Subconjunctival Injection of Hyaluronic Acid-Coated Nanoparticles for Drug Delivery to Posterior Eye
  Tsai, C. H., Hoang, L. N., Lin, C. C., Pan, L. C., Wu, C. L., Lin, I. C., Wang, P. Y. & Tseng, C. L., Jun 2022, In: Pharmaceutics. 14, 6, 1253.

• MicroRNA Therapy for Dry Eye Disease
  Liao, C. H., Tseng, C. L., Lin, S. L., Liang, C. L. & Juo, S. H. H., Mar 2022, In: Journal of Ocular Pharmacology and Therapeutics. 38, 2, p. 125-132 8 p.

• Segmental Tissue Speckle Tracking Predicts the Stenosis Severity in Patients With Coronary Artery Disease
  Chaichuum, S., Chiang, S.-J., Daimon, M., Chang, S.-C., Chan, C.-L., Hsu, C.-Y., Chen, H.-H. & Tseng, C.-L., Feb 2022, In: Frontiers in Cardiovascular Medicine. 8, p. 832096

• Study on Keratin/PEGDA Composite Hydrogel with the Addition of Varied Hair Protein Fractions
  Chen, Y., Wang, C. C., Ma, Y. S., Chao, Y. Y., Tseng, C. L. & Wei, Y., 2022, (Accepted/In press) In: ACS Applied Polymer Materials. 4, 5, p. 3426-3437 12 p.

• Topical application of TAK1 inhibitor encapsulated by gelatin particle alleviates corneal neovascularization
  Wang, J. H., Tseng, C. L., Lin, F. L., Chen, J., Hsieh, E. H., Lama, S., Chuang, Y. F., Kumar, S., Zhu, L., McGuinness, M. B., Hernandez, J., Tu, L., Wang, P. Y. & Liu, G. S., 2022, In: Theranostics. 12, 2, p. 657-674 18 p.

2021

• Assessing suitability of co@au core/shell nanoparticle geometry for improved theranostics in colon carcinoma
  Dhawan, U., Tseng, C. L., Wang, H. Y., Hsu, S. Y., Tsai, M. T. & Chung, R. J., Aug 2021, In: Nanomaterials. 11, 8, 2048.

• Development of lutein-containing eye drops for the treatment of dry eye syndrome
  Chen, Y. Z., Chen, Z. Y., Tang, Y. J., Tsai, C. H., Chuang, Y. L., Hsieh, E. H., Tucker, L., Lin, I. C. & Tseng, C. L., Nov 2021, In: Pharmaceutics. 13, 11, 1801.

• Dual-Targeting Glycol Chitosan/Heparin-Decorated Polypyrrole Nanoparticle for Augmented Photothermal Thrombolytic Therapy
  Lu, T. Y., Chiang, C. Y., Fan, Y. J., Jheng, P. R., Quiñones, E. D., Liu, K. T., Kuo, S. H., Hsieh, H. Y., Tseng, C. L., Yu, J. & Chuang, E. Y., 2021, (Accepted/In press) In: ACS Applied Materials and Interfaces. 13, 8, p. 10287-10300 14 p.

• Effects of eye drops containing hyaluronic acid-nimesulide conjugates in a benzalkonium chloride-induced experimental dry eye rabbit model
  Chen, T. Y., Tseng, C. L., Lin, C. A., Lin, H. Y., Venkatesan, P. & Lai, P. S., 2021, In: Pharmaceutics. 13, 9, 1366.

• Substitutes and colloidal system for vitreous replacement and drug delivery: Recent progress and future prospective
  Thacker, M., Tseng, C. L. & Lin, F. H., Jan 2021, In: Polymers. 13, 1, p. 1-15 15 p., 121.

• Template-free synthesis of mesoporous Ce3NbO7/CeO2 hollow nanospheres for label-free electrochemical immunosensing of leptin
  Liu, X., Tseng, C. L., Lin, L. Y., Lee, C. A., Li, J., Feng, L., Song, L., Li, X., He, J. H., Sakthivel, R. & Chung, R. J., Aug 2021, In: Sensors and Actuators, B: Chemical. 341, 130005.

2020

• Effects of lysosomal deposition on the friction coefficient of hydrogel contact lenses
  Su, C. Y., Yeh, L. K., Lai, C. C., Li, K. Y., Tseng, C. L. & Fang, H. W., Apr 1 2020, In: Contact Lens and Anterior Eye. 43, 2, p. 144-148 5 p.

• Enhancement of the permeability and activities of epigallocatechin gallate by quaternary ammonium chitosan/fucoidan nanoparticles
  Huang, T. W., Ho, Y. C., Tsai, T. N., Tseng, C. L., Lin, C. & Mi, F. L., Aug 15 2020, In: Carbohydrate Polymers. 242, 116312.

• Hyperthermia-induced controlled local anesthesia administration using gelatin-coated iron–gold alloy nanoparticles
  Ting, C. K., Dhawan, U., Tseng, C. L., Gong, C. S. A., Liu, W. C., Tsai, H. D. & Chung, R. J., Nov 2020, In: Pharmaceutics. 12, 11, p. 1-14 14 p., 1097.

• Mucoadhesive Bletilla striata polysaccharide-based artificial tears to relieve symptoms and inflammation in rabbit with dry eyes syndrome
  Thacker, M., Tseng, C. L., Chang, C. Y., Jakfar, S., Chen, H. Y. & Lin, F. H., Jul 1 2020, In: Polymers. 12, 7, 1465.

• The bio-tribological effect of poly-gamma-glutamic acid in the lysozyme-ionic contact lens system
  Su, C. Y., Yeh, L. K., Lai, C. C., Dubuisson, M., Tsao, Y. F., Tseng, C. L. & Fang, H. W., Jan 1 2020, In: Polymers. 12, 1, 156.

• The Synergistic Anticancer Effect of Dual Drug- (Cisplatin/Epigallocatechin Gallate) Loaded Gelatin Nanoparticles for Lung Cancer Treatment
  Chen, Y. J., Wang, Z. W., Lu, T. L., Gomez, C. B., Fang, H. W., Wei, Y. & Tseng, C. L., 2020, In: Journal of Nanomaterials. 2020, 9181549.

• Topical application of hyaluronic acid-RGD peptide-coated gelatin/epigallocatechin-3 gallate (EGCG) nanoparticles inhibits corneal neovascularization via inhibition of VEGF production
  Miyagawa, T., Chen, Z. Y., Chang, C. Y., Chen, K. H., Wang, Y. K., Liu, G. S. & Tseng, C. L., Apr 28 2020, In: Pharmaceutics. 12, 5, 404.

2019

• A bioinspired hyperthermic macrophage-based polypyrrole-polyethylenimine (Ppy-PEI) nanocomplex carrier to prevent and disrupt thrombotic fibrin clots
  Burnouf, T., Chen, C. H., Tan, S. J., Tseng, C. L., Lu, K. Y., Chang, L. H., Nyambat, B., Huang, S. C., Jheng, P. R., Aditya, R. N., Mi, F. L. & Chuang, E. Y., Sept 15 2019, In: Acta Biomaterialia. 96, p. 468-479 12 p.

• Development of Kaempferol-loaded gelatin nanoparticles for the treatment of corneal neovascularization in mice
  Chuang, Y. L., Fang, H. W., Ajitsaria, A., Chen, K. H., Su, C. Y., Liu, G. S. & Tseng, C. L., Dec 2019, In: Pharmaceutics. 11, 12, 635.

• Dry Eye Disease: A Review of Epidemiology in Taiwan, and its Clinical Treatment and Merits
  Kuo, Y.-K., Lin, I.-C., Chien, L.-N., Lin, T.-Y., How, Y.-T., Chen, K.-H., Dusting, G. J. & Tseng, C.-L., Aug 15 2019, In: Journal of Clinical Medicine. 8, 8, p. 1227

• Poly-gamma-glutamic acid functions as an effective lubricant with antimicrobial activity in multipurpose contact lens care solutions
  Su, C. Y., Tseng, C. L., Wu, S. H., Shih, B. W., Chen, Y. Z. & Fang, H. W., Jun 1 2019, In: Polymers. 11, 6, 1050.

• Strategy on Persisting in Distinct Activity of Plasmon-Activated Water
  Yang, C. P., Tsai, H. Y., Tseng, C. L., Hao, P. J. & Liu, Y. C., Dec 17 2019, In: ACS Omega. 4, 25, p. 21197-21203 7 p.

• The effects of different dynamic culture systems on cell proliferation and osteogenic differentiation in human mesenchymal stem cells
  Tsai, H. H., Yang, K. C., Wu, M. H., Chen, J. C. & Tseng, C. L., Aug 2 2019, In: International Journal of Molecular Sciences. 20, 16, 4024.

2018

• A gelatin hydrogel-containing nano-organic PEI–Ppy with a photothermal responsive effect for tissue engineering applications
  Satapathy, M. K., Nyambat, B., Chiang, C. W., Chen, C. H., Wong, P. C., Ho, P. H., Jheng, P. R., Burnouf, T., Tseng, C. L. & Chuang, E. Y., 2018, In: Molecules. 23, 6, 1256.

• Effect of hydroxyapatite formation on titanium surface with bone morphogenetic protein-2 loading through electrochemical deposition on MG-63 cells
  Huang, H. Y., Manga, Y. B., Huang, W. N., Lin, C. K., Tseng, C. L., Huang, H. M., Wu, C. Y. & Wu, C. C., Oct 4 2018, In: Materials. 11, 10, 1897.

• Gelatin–epigallocatechin gallate nanoparticles with hyaluronic acid decoration as eye drops can treat rabbit dry-eye syndrome effectively via inflammatory relief
  Huang, H. Y., Wang, M. C., Chen, Z. Y., Chiu, W. Y., Chen, K. H., Lin, I.-C., Yang, W.-C., Wu, C. C. & Tseng, C.-L., 2018, In: International Journal of Nanomedicine. 13, p. 7251-7273

• New Combination/Application of Polymer-Based Nanoparticles for Biomedical Engineering
  Chang, R., Wang, P. Y. & Tseng, C. L., Jan 1 2018, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 1078. p. 271-290 20 p. (Advances in Experimental Medicine and Biology; vol. 1078).

• Ocular drug delivery: Role of degradable polymeric nanocarriers for ophthalmic application
  Tsai, C. H., Wang, P. Y., Lin, I. C., Huang, H., Liu, G. S. & Tseng, C. L., Sept 19 2018, In: International Journal of Molecular Sciences. 19, 9, 2830.

• Polypyrrole electrode with a greater electroactive surface electrochemically polymerized in plasmon-activated water
  Chen, H. C., Chang, C. C., Yang, K. H., Mai, F. D., Tseng, C. L., Chen, L. Y., Hwang, B. J. & Liu, Y. C., Jan 2018, In: Journal of the Taiwan Institute of Chemical Engineers. 82, p. 252-260 9 p.

• Reflections on dry eye syndrome treatment: Therapeutic role of blood products
  Drew, V. J., Tseng, C. L., Seghatchian, J. & Burnouf, T., Feb 1 2018, In: Frontiers in Medicine. 5, FEB, 33.

• The characteristics of a preservative-free contact lens care solution on lysozyme adsorption and interfacial friction behavior
  Su, C. Y., Lai, C. C., Yeh, L. K., Li, K. Y., Shih, B. W., Tseng, C. L. & Fang, H. W., Nov 1 2018, In: Colloids and Surfaces B: Biointerfaces. 171, p. 538-543 6 p.