獎項與論文 Awards & Publications
Awards
Awards
Drug candidate: EI-1071
Inventor: Hung-Kai Chen, MD, PhD.
Collaborator: Elixiron Immunotherapeutics Inc., Taiwan
Types: Small molecule (inhibitor)
Target: CSF-1R
Indication: Alzheimer's disease
Administration route: Oral
Issuer: Alzheimer’s Association and Bill Gates
Funding: 800,000 USD
Issuer: Alzheimer’s Association and Bill Gates
Funding: 1,000,000 USD
Publications
Publications
2023
Cell Rep Med. 2023 Aug 15;4(8):101154. doi: 10.1016/j.xcrm.2023.101154.
BF10 demonstrates efficacy against macrophage-enriched tumors
BF10 depletes tumor-associated macrophages
BF10 enhances cytotoxicity and metabolic reprogramming of CD8+ T cells
The combination of BF10 and αPD-1 further enhances antitumor activity