Publications

Publications in indexed Journals and by international publishers

1. Joseph N, Hoskin PJ. When to hold and when to fold: The Clinical Approach to Locoregional recurrence after curative treatment of solid cancers. Clin Oncol (R Coll Radiol). 2025;42:103951. https://doi.org/10.1016/j.clon.2025.103951 (First and Corresponding Author)

2. Joseph N, Peiris V, Bamunuarachchi V, Abeysinghe P, Jeyakumaran N, Jayathilake D, Perera K, Fernandopulle R, Gunasekera S. Wisely frugal: ensuring sustainable funding for novel cancer therapeutics through a budget impact analysis in resource-limited settings. ecancermedicalscience 2025;19:1941. https://doi.org/10.3332/ecancer.2025.1941 (First and Corresponding author)

3. Bamunuarachchi V, Peiris V, Wijeskera S, Rajapakse D, Gunasekera S, Joseph N. Is the Juice Worth the Squeeze? Overall Survival Gain per Unit Treatment Time as a Metric of Clinical Benefit of Systemic Treatment. Clin Oncol (R Coll Radiol). 2025 Jun;42:103840. https://doi.org/10.1016/j.clon.2025.103840. (Senior and Corresponding author)

4. Joseph N, Alagiyawanna L, Ruwanpura T, Gunasekera S, Ruvinda L, Madushan S, Choudhury A. Whole-body integral dose and post-radiotherapy lymphocytopaenia in solid tumours. BMJ Oncology. 2025;4:e000522 https://doi.org/10.1136/bmjonc-2024-000522 (First and Corresponding Author)

5. Joseph N, Choudhury A, Dale R. Demystifying the radiobiology of hypofractionation: Simple equations to determine tumour alpha beta ratio. The Royal College of Radiologists Open. 2025 Jan 1;3:100159. https://doi.org/10.1016/j.rcro.2024.100159 (Frist Author)

6. Smith TAD, West CML, Joseph N, Lane B, Irlam-Jones J, More E, Mistry H, Reeves KJ, Song YP, Reardon M, Hoskin PJ, Hussain SA, Denley H, Hall E, Porta N, Huddart RA, James ND, Choudhury A. A hypoxia biomarker does not predict benefit from giving chemotherapy with radiotherapy in the BC2001 randomised controlled trial. EBioMedicine. 2024 Feb 21;101:105032. doi: 10.1016/j.ebiom.2024.105032 https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00067-7/fulltext

7. Alagiyawanna L, Wijesekera S, Peiris V, Silva DC, Rupasinghe TM, Balawardena J, Skandarajah T, Jeyakumaran N, Gunasekera D and Joseph N. Lung Cancer Survival in Sri Lanka. Accepted for publication in the South Asian Journal of Cancer 2023. https://doi.org/10.1055/s-0042-1755576 (Senior and Corresponding Author)

8. Iqbal A and Joseph N. Cervical Cancer in Sri Lanka. South Asian Journal of Cancer 2023;12(1):39–40. https://doi.org/10.1055/s-0043-1764236 (Senior Author)

9. Wijesekera S, Alagiyawanna L, Peiris V, Silva DC, Rupasinghe TM, Balawardena J, Skandarajah T, Jeyakumaran N, Gunasekera D, Bandusena MM and Joseph N.  Outcomes of Patients with Oesophageal and Gastric Cancer in Sri Lanka: A retrospective survival analysis. Journal of Cancer Research and Therapeutics 2023; doi: 10.4103/jcrt.jcrt_817_21  (Senior and Corresponding author) https://journals.lww.com/cancerjournal/Abstract/9000/Outcomes_of_patients_with_esophageal_and_gastric.99806.aspx

10. K, Wu Y, Chakraborty S, Elhusseiny G, Gondhowiardjo S, Joseph N, Lee AWM, Loong HH, Msadabwe-Chikuni SC, Tan BF, Ospina AV, Roques T, Shum HM, Yeoh EK. Global Health System Resilience during Encounters with Stressors - Lessons Learnt from Cancer Services during the COVID-19 Pandemic. Clinical Oncology. 2023 Jan 17:S0936-6555(23)00006-7. https://doi.org/10.1016/j.clon.2023.01.004 

11. Elumalai T, Joseph N, Choudhury A. Myths about bladder preservation in muscle invasive bladder cancer. Seminars in Radiation Oncology 2023;33(1):56-6. https://doi.org/10.1016/j.semradonc.2022.10.007 

12. Joseph N, Cicchetti A, McWilliam A, Webb A, Seibold P et al. High weekly integral dose and larger fraction size increase risk of fatigue and worsening of functional outcomes following radiotherapy for localized prostate cancer. Frontiers in Oncology. 2022  Oct 26;12:937934. https://doi.org/10.3389/fonc.2022.937934 (First and Corresponding Author)

13. Gulstene S, Ruwanpura T, Palma D, Joseph N. SABR in the treatment of early-stage lung cancer – a done deal?. Clin Oncol (R Coll Radiol). 2022 Aug 29. https://doi.org/10.1016/j.clon.2022.08.027   (Senior and Corresponding Author).

14. Hewage SA, Samaraweera S, Joseph N, Kularatna S, Gunawardena N. Presentation, Diagnosis and Treatment Delays in Breast Cancer Care and Their Associations in Sri Lanka, a Low-resourced Country. Clinical Oncology. 2022 Jun 4. https://doi.10.1016/j.clon.2022.05.007 

15. Gunasekera S, Seneviratne S, Jalink M, Joseph N, Ariyarathna Y, Booth CM, WIjeratne DT. Clinical Oncology Workload in Sri Lanka: Infrastructure, Supports, and Delivery of Clinical Care.  JCO Global Oncology 2021;7:1703-1710. DOI: 10.1200/GO.21.00345 https://ascopubs.org/doi/full/10.1200/GO.21.00345 

16. Rupasinghe T, Silva DC,Balawardena J, Perera K, Gunasekera D, Weerasinghe S, Jeyakumaran N, Abeysinghe P, Skandarajah T, Choudhury A and Joseph N. Curative intent radiotherapy for squamous cell carcinoma of the head and neck in Sri Lanka: The impact of radiotherapy technique on survival. Accepted for publication in Clinical Oncology 2021; 33(12):765-772. DOI: 10.1016/j.clon.2021.09.017 https://www.sciencedirect.com/science/article/pii/S0936655521003605 (Senior and Corresponding author)

17. Joseph N. Optimizing organ preservation strategies in localized muscle invasive bladder cancer. International Journal of Radiation Oncology Biology and Physics. 2021;111(5):1097-1100. DOI: 10.1016/j.ijrobp.2021.09.021 https://www.redjournal.org/article/S0360-3016(21)02820-0/fulltext

18. Wilson F, Joseph N, Choudhury A. Biomarkers in Muscles Invasive Bladder Cancer. Advances in Clinical Chemistry 2021.  doi:10.1016/bs.acc.2021.07.005 https://www.sciencedirect.com/science/article/abs/pii/S0065242321000585 (co-author)

19. Karunaratne B, Munasinghe F, Nadeekantha P, Kumarasiri S, Mallawarachchi K, Chulasiri P, Hewage S, Joseph N. The impact of the “lockdown” on medical oncology services in Sri Lanka. Clinical Oncology. 2021;33(12):e615. DOI:10.1016/j.clon.2021.08.006 https://www.clinicaloncologyonline.net/article/S0936-6555(21)00292-2/fulltext   (Senior Author).

20. Mariam NBG, Song YP, Joseph N et al.  Hypofractionation; Less is more? OncoTarget. 2021;12:1729-1733. doi:10.18632/oncotarget.28023 https://www.oncotarget.com/article/28023/text/   (Co-author)

21. Choudhury A, Henry A, Mitin, T, Chen R, Joseph N, Spratt D. Photons, Protons, SBRT, Brachytherapy- What is leading the charge for the management of prostate cancer? A Perspective From the GU Editorial Team. International Journal of Radiation Oncology Biology and Physics. 2021;110:1107-1114. doi:10.1016/j.ijrobp.2021.01.003  https://www.redjournal.org/article/S0360-3016(21)00005-5/fulltext (Co-author)

22. Hewage S, Samaraweera S, Joseph N et al. Does the choice of care pathways matter in timely breast cancer care in Sri Lanka? Cancer Epidemiology. 2021 Feb;70:101862. doi:10.1016/j.canep.2020.101862  https://www.sciencedirect.com/science/article/pii/S187778212030196X (Co-author)

23. Joseph N, Jayalth H, Balwardena J et al. Radical external beam radiotherapy in combination with brachytherapy for cervical cancer in Sri Lanka: Is treatment delayed treatment denied? JCO Global Oncology. 2020 Oct;6:1574-1581. doi: 10.1200/GO.20.00196.  https://ascopubs.org/doi/10.1200/GO.20.00196 (First and Corresponding author)

24. Joseph N, Choudhury A. Dosimetric predictors of radiotherapy induced lymphocytopaenia. Journal of Thoracic Oncology. 2021 Feb;16(2):e11-e12. doi:10.1016/j.jtho.2020.06.022 https://www.jto.org/article/S1556-0864(20)30549-9/fulltext (First and Corresponding author)

25. Joseph N, Kirkby NF, Hoskin PJ, West CML, Choudhury A, Dale RG. Radiobiologically-derived biphasic fractionation schemes to overcome the effects of tumour hypoxia. British Journal of Radiology. 2020;93:20190250. https://doi.org/10.1259/bjr.20190250  https://www.birpublications.org/doi/10.1259/bjr.20190250 (First and Corresponding author)

26. Joseph N, Choudhury A. Lymphocytopaenia and Radiotherapy Treatment Volumes in the Time of COVID-19. Clinical Oncology 2020;32:420-422. doi:10.1016/j.clon.2020.04.011 https://www.clinicaloncologyonline.net/article/S0936-6555(20)30189-8/fulltext (First author)

27. Balawardena J, Skandarajah T, Rathnayake W, Joseph N. Breast Cancer Survival in Sri Lanka. JCO Global Oncology. April 2020. doi:10.1200/JGO.20.00003 https://ascopubs.org/doi/10.1200/JGO.20.00003 (Senior and Corresponding author) 

28. Joseph N, Anjanappa M, Choudhury A. Treatment of Primary in Metastatic Prostate Cancer: What Is the Standard of Care?. The Cancer Journal. 2020 Jan 1;26(1):83-6. https://doi.org/10.1097/ppo.0000000000000430 (First and Corresponding author) 

29. Joseph N, Gunasekera S, Ariyaratne Y, Choudhury A. Clinical Oncology in Sri Lanka: Embracing the Promise of the Future. International Journal of Radiation Oncology, Biology and Physics. 2019 Nov 1;105(3):466-70. https://doi.org/10.1016/j.radonc.2019.03.008 (First and Corresponding author)

30. Joseph N, Choudhury A. SABR versus conventional fractionation regimens in NSCLC. Lancet Oncology. 2019 May 1;20(5):e231. https://doi.org/10.1016/s1470-2045(19)30180-9 (First and Corresponding author)

31. Joseph N, McWilliam A, Kennedy J. Post-treatment lymphocytopaenia, integral body dose and overall survival in lung cancer patients treated with radical radiotherapy. Radiotherapy and Oncology. 2019 Jun 1;135:115-9 https://doi.org/10.1016/j.radonc.2019.03.008.  (First and Corresponding author) 

32. Joseph N, Iype R, Choudhury A. The Future of Radiotherapy in Bladder Cancer. In: Soria F., Gontero P. (eds) Treating Urothelial Bladder Cancer. Springer, Cham. 2018:123-129. https://doi.org/10.1007/978-3-319-78559-2_16 (First author)

33. Thompson C, Joseph N, Sanderson B, Lyons J et al. Tolerability of Concurrent Chemoradiotherapy with Gemcitabine (GemX), with and without prior Neoadjuvant Chemotherapy in Muscle Invasive Bladder Cancer. International Journal of Radiation Oncology, Biology and Physics. 2017;97(4):732-739. http://dx.doi.org/10.1016/j.ijrobp.2016.11.040  (Joint First author)

34. Joseph N, Taylor C, O'Hara C et al . A combined single high dose rate brachytherapy boost in combination with external beam radiotherapy results in a high rate of biochemical disease free survival in intermediate and high risk localized prostate cancer. Radiotherapy and Oncology. 2016;121(2):299-303 https://doi.org/10.1016/j.radonc.2016.09.016 (First author) 

35. Joseph N and Choudhury A. Fit Patient with Nonmetastatic Castration-resistant Prostate Cancer, Lower Urinary Tract Symptoms, and Severe Recurrent Haematuria. European Urology Focus. 2016;2(5):477-478. https://doi.org/10.1016/j.euf.2016.08.008 (First author)

36. Joseph N and Choudhury A. Adjuvant chemotherapy is more suitable than neoadjuvant chemotherapy for muscle invasive bladder cancer patients treated with radical chemoradiotherapy. International Journal of Radiation Oncology, Biology, Physics 2016;96(3):613-615. https://doi.org/10.1016/j.ijrobp.2016.06.2452  (First and Corresponding author)

37. Joseph N, Dovedi SJ, Thompson C et al. Pre-treatment lymphocytopaenia is an adverse prognostic biomarker in muscle-invasive and advanced bladder cancer. Annals of Oncology. 2016;27(2):294-9. https://doi.org/10.1093/annonc/mdv546. (First author)

38. Lamabadusuriya SP, Karunaratne K, Joseph N et al. Invasive Haemophilus influenzae (Hib) disease in a tertiary care children's hospital. Ceylon Medical Journal. 2006;51(3):126 DOI: 10.4038/cmj.v51i3.1263 https://cmj.sljol.info/articles/abstract/10.4038/cmj.v51i3.1263/