Magic Mushrooms: What Effects Of Brain?

Have you ever wondered why magic mushrooms like those sold at Nupep Shrooms are some of the most widely used hallucinogens all over the world? The answer is simple: they enable you to have a dreamlike, otherworldly experience whenever you desire. But wouldn’t something so amazing become addictive? Not necessarily! On the contrary, there has been scientific evidence which suggests psilocybin mushrooms can be powerful tools in fighting addictions and even disorders like depression and anxiety.

The compound that gives magic mushrooms their powerful hallucinogenic character (thereby making them “magic”) is the naturally occuring psilocybin, found in more than 180 species of mushrooms in the genus psilocybe.

It is a prodrug which means that it needs to be metabolically converted into another compound psilocin before it can have any psychoactive effects on the brain. Both psilocybin and psilocin are tryptamines whose structures bear great similarity with that of serotonin, an essential neurotransmitter.

In fact, these compounds are so structurally similar that psilocin can bind to the receptors which were originally meant for serotonin. This in turn has a net effect of disrupting the connections within the brain of the user, especially in the prefrontal cortex which is responsible for perception, cognition and mood.

The mind-altering effects of psilocin have been extensively examined in various studies, including those which were focused on its ability to treat anxiety, depression and addiction.

In one particular study carried out by the Imperial College of London, it was shown via MRI that small doses of psilocybin had resulted in significant changes in brain activity. It was thus proposed that this chemical effectively reset the parts of the brain which are responsible for the feelings of depression and anxiety.

This reset was reportedly marked by a rapid, cathartic release of emotions, which again, shows how psilocybin differs from antidepressants and other traditional modes of treatment for these conditions, which are known to only cause the repression of emotion over an extended period of time.

Also, the reset mechanism is believed to be the reason why psilocybin has been proven to help individuals overcome addiction.

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