Our lab investigates the mechanisms and brain circuits in psychiatric disorders and their therapeutic potential, with a special interest for the cerebellum's role.
We are driven by a strong commitment to bridging the gap between clinical observations and translational applications, aiming to leverage neuroimaging-guided neuromodulation techniques to develop innovative therapeutic solutions along two axes:
Axis 1: Clinical and precision psychiatry aims to explore the neurobiological underpinnings of severe, treatment-resistant psychiatric disorders and schizophrenia in particular, using advanced neuroimaging and clinical assessments for deep phenotyping and patient stratification.
Axis 2: Translational & interventional psychiatry aims at translating findings into interventions, with a focus on neuroimaging-guided TMS to correct circuit abnormalities and improve clinical symptoms.
We have openings for master projects in our lab. Check out "Announcements for master projects" and contact us!
10.09.2026 - Indrit is Guest Editor, curating a special issue "The Cerebellum in Psychiatry: From Pathophysiology to Therapeutic Target", in Biological Psychiatry (IF = 10.3) with R.C.K. Chan, Hong Kong, and A. Giersch, Strasbourg). Approved September 2026; publication 2028.
01.09.2026 - ATHENA-II started! Our multicentre trial of connectivity-guided cerebellar TMS for motivation deficits in schizophrenia is now live in Geneva and Lausanne, funded by the Horten Health Foundation (4'000'000 CHF) with Indrit Bègue (HUG/UNIGE, principal investigator), Paul Klauser (CHUV), Mackenzie Mathis (EPFL) and Stefan Kaiser (HUG). Let's go!
15.01.2025 - Indrit obtained support from the Foundation Louis-Jeantet to support her work on cerebellar stimulation in schizophrenia (STARTER fund). Yay!
15.01.2025 - Indrit obtained support from the Synapsis Foundation for the estimation of brain disorders in Switzerland. Youpee!
Department of psychiatry
Synapsy center for neuroscience research in mental health
University of Geneva, Switzerland
Campus Biotech, Chemin des Mines 9, 1202