Publications

Nan Song's Bibliography link: https://www.ncbi.nlm.nih.gov/myncbi/10a3-y3o-euAx/bibliography/public/ 

1. Oh K, Yun D, Yang S, Yuk M, Lee C, Kim B, Heo S, Dong Q, Wang Z, Park H, Song N*. A genome-wide association study identifies Asian-specific genetic susceptibility for epigenetic age acceleration. GeroScience. 2025. Sep. [Accepted] (*Corresponding author)
   
   

2. Yuk M, Yang S, Yun D, Oh K, Han JM, Lim KH, Dong Q, Wang Z, Song N*. A genome-wide association study for lifetime estrogen exposure identifies novel loci and polygenic signals in East Asian postmenopausal women. Maturitas. 2025 Aug:199:108645. (*Corresponding author)
   
   

3. Meng X, Eulalio T, Kim Y, Easton J, Mulder HL, Walker E, Neale G, Song N, Shelton K, Howell RM, Xing M, Mirzaei S, Srivastava DK, Ky B, Dixon SB, Hudson MM, Ness KK, Armstrong GT, Wang Z. Epigenetic Age Acceleration Mediates Treatment Effects on Cardiometabolic and Cardiovascular Risk in Childhood Cancer Survivors. J Am Coll Cardiol CardioOnc. 2025 Jun. [ePublished]
   ⭐St. Jude Research⭐ ⭐Cure News⭐
   
   

4. CRISPR-mediated direct targeting of microRNA-33 rescues ApoE lipidation and amyloid-beta metabolism in ApoE4 sporadic Alzheimer’s disease. Brain. 2025 Jun [Accepted]
   
   

5. Yun D*, Yang JH*, Sim JA, Kim M, Park JW, Jeong SY, Shin A, Kweon SS**, Song N**. Identification of MMP14 and MKLN1 as colorectal cancer susceptibility genes and drug-repositioning candidates from a genome-wide association study. J Transl Med. 2025 May 14;23(1):543. (*Co-first author, **Co-corresponding author)
   
   

6. Lee J*, Yuk M*,  Youn J, Yang S, Oh K, Kim H, Kim T,  Kim K, Lee TY, Kim KS, Kang BK, Lee KE,  Song N**. Estimating treatment effect on timed 25-foot walk in multiple sclerosis: A systematic review and meta-analysis. Multiple Sclerosis and Related Disorders. 2025 May 197:106380. (*Co-first author, **Corresponding author)
   
   

7. Yun D*, Yang JH*, Yang S, Sim JA, Kim M, Park JW, Jeong SY, Shin A, Kweon SS**, Song N**. Novel genetic loci and functional properties of immune-related genes for colorectal cancer survival in Korea. BMC Cancer. 2025 Mar 13;25(1):456. (*Co-first author, **Co-corresponding author)
   
   

8. Park JS, Lee J, Wang F, Ma H, Zhou Z, Lee YS, Oh K, Lee H, Sui G, Lee S, Yang YM, Lee JW, Ji YH, Park CW, Yoo HS, Hwang BY, Han SB, Song N, Oh S, Kim B, Seki E, Hong JT, Roh YS.  A1AT dysregulation of metabolically stressed hepatocytes by Kupffer cells drives MASH and fibrosis. Exp Mol Med. 2025 Feb 12;57(2):450-465.
   
   

9. Oh K, Yuk M, Yang S, Youn J, Dong Q, Wang Z, Song N*. A genome-wide association study of high-sensitivity C-reactive protein in a large Korean population highlights its genetic relationship with cholesterol metabolism. Sci Rep. 2025 Jan 2;15(1):189. (*Corresponding author)
   
   

10. Chen C, Plonski NM, Dong Q, Song N, Zhang X, Parikh HM, Finch ER, Easton J, Mulder HL, Walker E, Neale G, Pan Y, Li Q, Zhang J, Krull K, Robison LL, Armstrong GT, Yasui Y, Ness KK, Hudson MM, Wang H, Huang IC, Wang Z. Race and Ethnicity, Socioeconomic Factors, and Epigenetic Age Acceleration in Survivors of Childhood Cancer. JAMA Netw Open. 2024 Jul 1;7(7):e2419771.
    
    

11. Plonski NM, Pan Y, Chen C, Dong Q, Zhang X, Song N, Shelton K, Easton J, Mulder H, Zhang J, Neale G, Walker E, Wang H, Webster R, Brinkman T, Krull KR, Armstrong GT, Ness KK, Hudson MM, Li Q, Huang IC, Wang Z. Health-Related quality of life and DNA Methylation-Based aging biomarkers among survivors of childhood cancer. J Natl Cancer Inst. 2024 Jul 1;116(7):1116-1125
    
    

12. Chen C, Qin N, Wang M, Dong Q, Tithi SS, Hui Y, Chen W, Wu G, Kennetz D, Edmonson MN, Rusch , Thrasher A, Easton J, Mulder HL, Song N, Plonski N-M, Shelton K, Im C, Ehrhardt MJ, Nichols KE, Leisenring WM, Stratton KL, Howell R, Yasui Y, Bhatia S, Armstrong GT, Ness KK, Hudson MM, Zhang J, Wang H, Srivastava DK, Robison LL, Wang Z. Cancer germline predisposing variants and late mortality from subsequent malignant neoplasms among long-term childhood cancer survivors: a report from the St Jude Lifetime Cohort and the Childhood Cancer Survivor Study. Lancet Oncol 2023; 24: 1147–56 
    
    

13. Lee HC, Yang EH, Shin S, Moon SH, Song N, Ryoo JH.  Correlation of commute time with the risk of subjective mental health problems: 6th Korean Working Conditions Survey (KWCS). Ann Occup Environ Med. 2023 May 11;35(1):e9.
    
    

14. Plonski NM, Chen C, Dong Q, Qin N, Song N, Parikh HM, Shelton K, Finch ER, Easton J, Mulder H, Zhang J, Neale G, Walker E, Wang H, Krull K, Ness KK, Hudson MM, Robison LL, Li Q, Williams A, Wang Z. Epigenetic Age in Peripheral Blood Among Children, Adolescent, and Adult Survivors of Childhood Cancer. JAMA Netw Open. 2023 Apr 3;6(4):e2310325.
    
    

15. Dong Q, Chen C, Song N, Qin N, Plonski NM, Finch ER, Shelton K, Easton J, Mulder H, Plyer E, Neale G, Walker E, Li Q, Huang IC, Zhang J, Wang H, Hudson MM, Robison LL, Ness KK, Wang Z. Distinct DNA methylation signatures associated with blood lipids as exposures or outcomes among survivors of childhood cancer: a report from the St. Jude lifetime cohort . Clin Epigenetics. 2023 Feb 28;15(1):32.
    
    

16. Song N, Dong Q, Chen C, Li Q, Mulder H, Plyler E, Easton J, Walker E, Olson S, Neale G, Krull KR, Srivastava DK, Ness KK, Zhang J, Hudson MM, Robison LL, Huang IC, Wang Z. Social-epigenetic mediators for racial disparities in pulmonary impairment among childhood cancer survivors. Cancer Commun (Lond). 2023 Feb;43(2):290-293.
    ⭐BRIC 한빛사⭐
    
    

17. Song N, Sim JA, Dong Q, Zheng Y, Hou L, Li Z, Hsu C-W, Pan H, Mulder H, Easton J, Walker E, Neale G, Wilson CL, Ness KK, Krull KR, Srivastava DK, Yasui Y, Zhang J, Hudson MM, Robison LL, Huang IC, Wang Z. Blood DNA methylation signatures are associated with social determinants of health among survivors of childhood cancer. Epigenetics. 2022 Nov;17(11):1389-1403.

18. Chen C*, Song N*, Dong Q*, Sun X, Mulder HL, Easton J, Zhang J, Yasui Y, Bhatia S, Armstrong GT, Wang H, Ness KK, Hudson MM, Robison LL, Wang Z. Association of Single-Nucleotide Variants in the Human Leukocyte Antigen and Other Loci With Childhood Hodgkin Lymphoma. JAMA Network Open. 2022 Aug 1;5(8):e2225647. (*Co-first author)
    ⭐BRIC 한빛사⭐ 

19. Dong Q*, Song N*, Qin N, Chen C, Li Z, Sun X, Easton J, Mulder H, Plyler E, Neale G, Walker E, Li Q, Ma X, Chen X, Huang I-C, Yasui Y, Ness KK, Zhang J, Hudson MM, Robison LL, Wang Z. Genome-wide association studies identify novel genetic loci for epigenetic age acceleration among survivors of childhood cancer. Genome Med. 2022 Mar 22;14(1):32. (*Co-first author)
    ⭐BRIC 한빛사⭐⭐St. Jude Media⭐

20. Song N, Liu Q, Wilson CL, Sapkota Y, Ehrhardt MJ, Gibson TM, Morton LM, Chanock SJ, Neglia JP, Arnold MA, Michael JR, Gout AM, Mulder HL, Easton J, Bhatia S, Armstrong GT, Zhang J, Delaney A, Hudson MM, Robison LL, Yasui Y, Wang Z. Polygenic Risk Score Improves Risk Stratification and Prediction of Subsequent Thyroid Cancer after Childhood Cancer. Cancer Epidemiol Biomarkers Prev. 2021 Nov;30(11):2096-2104.

21. Park J, Choi JY, Choi J, Chung S, Song N, Park SK, Han W, Noh DY, Ahn SH, Lee JW, Kim MK, Jee SH, Wen W, Bolla MK, Wang Q, Dennis J, Michailidou K, Shah M, Conroy DM, Harrington PA, Mayes R, Czene K, Hall P, Teras LR, Patel AV, Couch FJ, Olson JE, Sawyer EJ, Roylance R, Bojesen SE, Flyger H, Lambrechts D, Baten A, Matsuo K, Ito H, Guénel P, Truong T, Keeman R, Schmidt MK, Wu AH, Tseng CC, Cox A, Cross SS, Andrulis IL, Hopper JL, Southey MC, Wu PE, Shen CY, Fasching PA, Ekici AB, Muir K, Lophatananon A, Brenner H, Arndt V, Jones ME, Swerdlow AJ, Hoppe R, Ko YD, Hartman M, Li J, Mannermaa A, Hartikainen JM, Benitez J, González-Neira A, Haiman CA, Dörk T, Bogdanova NV, Teo SH, Taib NAM, Fletcher O, Johnson N, Grip M, Winqvist R, Blomqvist C, Nevanlinna H, Lindblom A, Wendt C, Kristensen VN, Tollenaar RAEM, Heemskerk-Gerritsen BAM, Radice P, Bonanni B, Hamann U, Manoochehri M, Lacey JV, Martinez ME, Dunning AM, Pharoah PDP, Easton DF, Yoo KY, Kang D, kConFab Investigators kConFab Investigators, NBCS Collaborators NBCS Collaborators. Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer: Can Gene-Environment Interactions Be Detected Only among Candidate SNPs from Genome-Wide Association Studies? Cancers (Basel). 2021 May 14;13(10). 

22. Qin N*, Li Z*, Song N*, Wilson CL, Easton J, Mulder H, Plyler E, Neale G, Walker E, Zhou X, Pan H, Hudson MM, Yasui Y, Robison LL, Zhang J, Ness KK, Wang Z. Epigenetic Age Acceleration and Chronic Health Conditions Among Adult Survivors of Childhood Cancer. J Natl Cancer Inst. 2021 May 4;113(5):597-605. (*Co-first author)
    ⭐BRIC 한빛사⭐ 

23. Song N, Hsu CW, Pan H, Zheng Y, Hou L, Sim JA, Li Z, Mulder H, Easton J, Walker E, Neale G, Wilson CL, Ness KK, Krull KR, Srivastava DK, Yasui Y, Zhang J, Hudson MM, Robison LL, Huang IC, Wang Z. Persistent variations of blood DNA methylation associated with treatment exposures and risk for cardiometabolic outcomes in long-term survivors of childhood cancer in the St. Jude Lifetime Cohort. Genome Med. 2021 Apr 6;13(1):53.
    ⭐BRIC 한빛사⭐ 

24. Huang D, Joo H, Song N, Cho S, Kim W, Shin A. Association between gallstones and the risk of biliary tract cancer: a systematic review and meta-analysis. Epidemiol Health. 2021;43:e2021011. Epub 2021 Feb 3.

25. Cho S, Song N, Choi JY, Shin A. Effect of Citric Acid Cycle Genetic Variants and Their Interactions with Obesity, Physical Activity and Energy Intake on the Risk of Colorectal Cancer: Results from a Nested Case-Control Study in the UK Biobank. Cancers (Basel). 2020 Oct 12;12(10).

26. Huang D, Lee J, Song N, Cho S, Choe S, Shin A. Gallstones, Cholecystectomy and the Risk of Hepatobiliary and Pancreatic Cancer: A Nationwide Population-based Cohort Study in Korea. J Cancer Prev. 2020 Sep 30;25(3):164-172.

27. Qin N, Wang Z, Liu Q, Song N, Wilson CL, Ehrhardt MJ, Shelton K, Easton J, Mulder H, Kennetz D, Edmonson MN, Rusch MC, Downing JR, Hudson MM, Nichols KE, Zhang J, Robison LL, Yasui Y. Pathogenic Germline Mutations in DNA Repair Genes in Combination With Cancer Treatment Exposures and Risk of Subsequent Neoplasms Among Long-Term Survivors of Childhood Cancer. J Clin Oncol. 2020 Aug 20;38(24):2728-2740.
    ⭐St. Jude Media⭐ 

28. Song N, Li Z, Qin N, Howell CR, Wilson CL, Easton J, Mulder HL, Edmonson MN, Rusch MC, Zhang J, Hudson MM, Yasui Y, Robison LL, Ness KK, Wang Z. Shortened Leukocyte Telomere Length Associates with an Increased Prevalence of Chronic Health Conditions among Survivors of Childhood Cancer: A Report from the St. Jude Lifetime Cohort. Clin Cancer Res. 2020 May 15;26(10):2362-2371.
    ⭐CCR Translations⭐⭐St. Jude Media ⭐⭐ASHG 2019 platform session⭐

29. Song N, Huang D, Jang D, Kim MJ, Jeong SY, Shin A, Park JW. Optimal Body Mass Index Cut-off Point for Predicting Colorectal Cancer Survival in an Asian Population: A National Health Information Database Analysis. Cancers (Basel). 2020 Mar 30;12(4).

30. Song N, Lee J, Cho S, Kim J, Oh JH, Shin A. Evaluation of gene-environment interactions for colorectal cancer susceptibility loci using case-only and case-control designs. BMC Cancer. 2019 Dec 18;19(1):1231.
    ⭐APOCP-9 2018 Best Poster Award⭐

31. Song N, Kim K, Shin A, Park JW, Chang HJ, Shi J, Cai Q, Kim DY, Zheng W, Oh JH. Colorectal cancer susceptibility loci and influence on survival. Genes, Chromosomes & Cancer. 2018 Dec;57(12):630-637.

32. Kim JE, Choi J, Park J, Park C, Lee SM, Park SE, Song N, Chung S, Sung H, Han W, Lee JW, Park SK, Kim MK, Noh DY, Yoo KY, Kang D, Choi JY. Associations between genetic polymorphisms of membrane transporter genes and prognosis after chemotherapy: meta-analysis and finding from Seoul Breast Cancer Study (SEBCS). Pharmacogenomics J. 2018 Sep; 18(5):633-645.

33. Song N, Shin A, Oh JH, Kim J. Effects of interactions between common genetic variants and alcohol consumption on colorectal cancer risk. Oncotarget. 2018 Jan 06;9(5):6391-6401.

34. Song N, Shin A, Jung HS, Oh JH. Effects of interactions between common genetic variants and smoking on colorectal cancer. BMC Cancer. 2017 Dec 19;17(1):869.

35. Song N, Shin A, Park JW, Kim J, Oh JH. Common risk variants for colorectal cancer: an evaluation of associations with age at cancer onset. Sci Rep. 2017 Jan 13;7:40644.
    ⭐APOCP-8 2016 Best Poster Award⭐⭐APOCP-8 2016 Emerging Researcher Award⭐

36. Song N, Choi JY, Sung H, Jeon S, Chung S, Song M, Park SK, Han W, Lee JW, Kim MK, Yoo KY, Ahn SH, Noh DY, Kang D. Tumor subtype-specific associations of hormone-related reproductive factors on breast cancer survival. PLoS One. 2015 Apr 14;10(4):e0123994.

37. Song N, Choi JY, Sung H, Jeon S, Chung S, Park SK, Han W, Lee JW, Kim MK, Lee JY, Yoo KY, Han BG, Ahn SH, Noh DY, Kang D. Prediction of breast cancer survival using clinical and genetic markers by tumor subtypes. PLoS One. 2015 Apr 13;10(4):e0122413.

38. Choi J, Song N, Han S, Chung S, Sung H, Lee JY, Jung S, Park SK, Yoo KY, Han W, Lee JW, Noh DY, Kang D, Choi JY. The associations between immunity-related genes and breast cancer prognosis in Korean women. PLoS One. 2014 Jul 30;9(7):e103593.

39. Song N, Choi JY, Sung H, Chung S, Song M, Park SK, Han W, Lee JW, Kim MK, Yoo KY, Ahn SH, Noh DY, Kang D. Heterogeneity of epidemiological factors by breast tumor subtypes in Korean women: a case-case study. Int J Cancer. 2014 Aug 1;135(3):669-81.
    ⭐Korea Cancer Research Foundation 2014 Best Research Award⭐

40. Jung SJ, Song M, Choi JY, Song N, Park SK, Yoo KY, Kang D. Association of selected medical conditions with breast cancer risk in Korea. J Prev Med Public Health. 2013 Nov;46(6):346-52.

41. Chung S, Park SK, Sung H, Song N, Han W, Noh DY, Ahn SH, Yoo KY, Choi JY, Kang D. Association between chronological change of reproductive factors and breast cancer risk defined by hormone receptor status: results from the Seoul Breast Cancer Study. Breast Cancer Res Treat. 2013 Aug;140(3):557-65.

42. Song N, Sung H, Choi JY, Han S, Jeon S, Song M, Lee Y, Park C, Park SK, Lee KM, Yoo KY, Noh DY, Ahn SH, Lee SA, Kang D. Preoperative serum levels of matrix metalloproteinase-2 (MMP-2) and survival of breast cancer among Korean women. Cancer Epidemiol Biomarkers Prev. 2012 Aug;21(8):1371-80.

43. Park C, Han S, Lee KM, Choi JY, Song N, Jeon S, Park SK, Ahn HS, Shin HY, Kang HJ, Koo HH, Seo JJ, Choi JE, Kang D. Association between CASP7 and CASP14 genetic polymorphisms and the risk of childhood leukemia. Hum Immunol. 2012 Jul;73(7):736-9.

44. Song N, Han S, Lee KM, Choi JY, Park SK, Jeon S, Lee Y, Ahn HS, Shin HY, Kang HJ, Koo HH, Seo JJ, Choi JE, Kang D. Genetic variants in interleukin-2 and risk of lymphoma among children in Korea. Asian Pac J Cancer Prev. 2012;13(2):621-3.

Patents

1. [특허출원]  임기환, 한상배, 송난, 박한슬, 이화형, 김영준, 정영훈. 시신경척수염 조기 진단용 S100a8 마커 및 이의 용도.
   (출원번호: 10-2025-0106625) 2025.08.04.
   
   

2. [특허출원] 박지원, 정승용, 신애선, 김민정, 심진아, 송난, 유지원, 유수현. 대장암 환자 건강관리 시스템.
   (출원번호: 10-2025-0091768) 2025.07.08.
   
   

3. [특허출원] 송난, 오광연, 윤다빈, 양소윤, 육민주, 이창규, 김보영, 허수연, 박한슬. 후성유전학 노화 가속 특이적 바이오 마커.
   (출원번호: 10-2025-0080534) 2025.06.18.
   
   

4. [특허출원] 송난, 윤다빈, 오광연.  후성유전학적 생체 나이 예측 방법 및 시스템.
   (출원번호: 10-2025-0068163) 2025.05.26.
   
   

5. [특허출원] 송난, 윤다빈, 김민정, 박지원, 정승용, 신애선, 권순석, 양정호, 심진아.  대장암과 관련된 단일 염기 다형성 및 이의 용도.
   (출원번호: 10-2024-0196750) 2024.12.26.