Publications

144. Piccialli, Vincenzo; Borbone, Nicola; Terracciano, Monica

(2R,3R,5R,6S)-5-Bromo-2-{[(2R,3R,5R)-3-bromo-5-(propa-1,2-dien-1-yl)tetrahydro-furan-2-yl]methyl}-6-ethyltetrahydro-2H-pyran-3-ol

From Molbank (2026), 2026, M2137. DOI:10.3390/M2137

143. Nolli, Maria Grazia; Bartocci, Alessio; De Rosa, Caterina; Falanga, Andrea Patrizia; Abbate, Vincenzo; Terracciano, Monica; Nocerino, Valeria; Rea, Ilaria; De Stefano, Luca; Giordano, Sabrina; Piccialli, Gennaro; Costantino, Marco Fabio; Della Corte, Carminia Maria; Dumont, Elise; Borbone, Nicola; Dell'Aversana, Giovanni Orabona; Oliviero, Giorgia

Truncated PNA-Functionalized Porous Silicon Biosensor for Low-Cost and Early Detection of Troponin T in Myocardial Infarction

From Talanta (2026), 299, 129054. DOI:10.1016/j.talanta.2025.129054

142. Falanga, Andrea Patrizia; Farina, Maria Vittoria; Cianfoni, Gabriele; Barolo, Lorenzo; Di Meo, Chiara; Borsatti, Giulia Elizabeth; Ghirga, Francesca; Botta, Bruno; Pisano, Luca; Borbone, Nicola; D'Errico, Stefano; Paone, Alessio; Oliviero, Giorgia; Quaglio, Deborah; Baiocco, Paola

Evaluation of Peptide Nucleic Acid Encapsulation in Ferritin Nanocages for Gene Silencing Applications

From Biomacromolecules (2025), article in press. DOI:10.1021/acs.biomac.5c01489

141. Falanga, Andrea Patrizia; Mahal, Ahmed; Marzano, Maria; D'Errico, Stefano; Secondo, Agnese; Piccialli, Ilaria; Borbone, Nicola

The evolving chemistry of cADPR analogues: from marine discovery to calcium signaling tools

From Bioorganic Chemistry (2025), 166, 109055. DOI:10.1016/j.bioorg.2025.109055

140. Marzano, Maria; Nolli, Maria Grazia; D'Errico, Stefano; Falanga, Andrea Patrizia; Terracciano, Monica; Dardano, Principia; De Stefano, Luca; Piccialli, Gennaro; Borbone, Nicola; Oliviero, Giorgia

Enhancing G-Quadruplex-Based DNA Nanotechnology: New Lipophilic DNA G-quadruplexes with TBDPS Modifications

From RSC Advances (2025), 15, 17933–17945. DOI:10.1039/D5RA01033K

139. Giordano, Sabrina; Terracciano, Monica; Gallo, Enrico; Diaferia, Carlo; Falanga, Andrea Patrizia.; Accardo, Antonella; Franzese, Monica; Salvatore, Marco; Piccialli, Gennaro; Borbone, Nicola; Oliviero, Giorgia

Investigating the Interactions of Peptide Nucleic Acids with Multicomponent Peptide Hydrogels for the Advancement of Healthcare Technologies

From Gels (2025), 11, 367. DOI:10.3390/gels11050367

138. Cardano, Francesca; Massaro, Marina; Leone, Federica; Cinà, Giuseppe; Borbone, Nicola; Falanga, Andrea P.; Oliviero, Giorgia; Nicosia, Angelo; Fresia, Martina; Fin, Andrea; Scardaci, Vittorio; Barbosa, Raquel de Melo; Riela, Serena

Halloysite nanotubes functionalized with naphthalene diimide and peptide nucleic acid derivatives: Toward multifunctional nanomaterials

From ACS Applied Nano Materials (2025), 8, 12775-12783. DOI:10.1021/acsanm.5c02027

137. De Chiara, Arianna; Falanga, Andrea Patrizia; Froechlich, Guendalina; Borbone, Nicola; Campanile, Andrea; Pellino, Emilio; Piccialli, Gennaro; Nicosia, Alfredo; Oliviero, Giorgia; Sasso, Emanuele

Peptide nucleic acid-mediated circularization of target RNA as tool to inhibit translation

From International Journal of Biological Macromolecules (2025), 308, 142230. DOI:10.1016/j.ijbiomac.2025.142230

136. Falanga, Andrea Patrizia; Cremonini, Maria; Bartocci, Alessio; Nolli, Maria Grazia; Terracciano, Monica; Volpi, Stefano; Dumont, Elise; Piccialli, Gennaro; Casnati, Alessandro; Sansone, Francesco; Borbone, Nicola; Oliviero, Giorgia

Calixarenes meet (TG4T)4 G-quadruplex: Exploring reciprocal interactions to develop innovative biotechnological applications

From International Journal of Biological Macromolecules (2025), 305, 141331. DOI:10.1016/j.ijbiomac.2025.141331

135. Raucci, Ada; Sorrentino, Giuseppina; Singh, Sima; Borbone, Nicola; Oliviero, Giorgia; Piccialli, Gennaro; Terracciano, Monica; Cinti, Stefano

Cost‑effective, user‑friendly detection and preconcentration of thrombin on a sustainable paper‑based electrochemical platform

From Analytical and Bioanalytical Chemistry (2025), 417, 1863–1872. DOI:10.1007/s00216-025-05764-9

134. Falanga, Andrea Patrizia; Piccialli, Ilaria; Greco, Francesca; D'Errico, Stefano; Nolli, Maria Grazia; Borbone, Nicola; Oliviero, Giorgia; Roviello, Giovanni Nicola

Nanostructural Modulation of G‐Quadruplex DNA in Neurodegeneration: Orotate Interaction Revealed Through Experimental and Computational Approaches

From Journal of Neurochemistry (2025), 169, e16296. DOI:10.1111/jnc.16296

133. Nolli, Maria Graza; Terracciano, Monica; Rea, Ilaria; D'Errico, Stefano; Placido Mineo, Giuseppe; De Stefano, Luca; Piccialli, Gennaro; Riela, Serena; Oliviero, Giorgia; Borbone, Nicola

Mild-Temperature Catalyzed Hydrosilylation for Simplified Carbohydrate Functionalization of Porous Silicon Nanoparticles

From Chemistry - A European Journal (2025), 31, e202402818. DOI:10.1002/chem.202402818

132. Falanga, Andrea Patrizia; Greco, Francesca; Terracciano, Monica; D'Errico, Stefano; Marzano, Maria; Feola, Sara; Sepe, Valentina; Fontana, Flavia; Piccialli, Ilaria; Cerullo, Vincenzo; Santo, Helder Almeida; Borbone, Nicola

Engineering an oncolytic adenoviral platform for precise delivery of antisense peptide nucleic acid to modulate PD-L1 overexpression in cancer cells

From International Journal of Pharmaceutics (2025), 668, 124941. DOI:10.1016/j.ijpharm.2024.124941

131. Gamberi, Chiara; Leverette, Chad L.; Davis, Alexis C.; Ismail, Moayad; Piccialli, Ilaria; Borbone, Nicola; Oliviero, Giorgia; Vicidomini, Caterina; Palumbo, Rosanna; Roviello, Giovanni Nicola

Oceanic Breakthroughs: Marine-derived innovations in vaccinations, therapy, and immune health

From Vaccines (2024), 12, 1263. DOI:10.3390/vaccines12111263

130. Falanga, Andrea Patrizia; D'Urso, Alessandro; Travagliante, Gabriele; Gangemi, Chiara Maria Antonietta; Marzano, Maria; D'Errico, Stefano; Terracciano, Monica; Greco, Francesca; De Stefano, Luca; Dardano, Principia; Rea, Ilaria; Piccialli, Gennaro; Oliviero, Giorgia; Borbone, Nicola

Higher-Order G-Quadruplex Structures and Porphyrin Ligands: Towards a Non-Ambiguous Relationship

From International Journal of Biological Macromolecules (2024), 268, 131801. DOI:10.1016/j.ijbiomac.2024.131801

129. Falanga, Andrea Patrizia; Massaro, Marina; Borbone, Nicola*; Notarbartolo, Monica; Piccialli, Gennaro; Liotta, Leonarda F.; Sanchez-Espejo, Rita; Viseras Iborra, Cesar; Raymo, Francisco M.; Oliviero, Giorgia; Riela, Serena

Carrier capability of halloysite nanotubes for the intracellular delivery of antisense PNA targeting mRNA of neuroglobin gene

From Journal of Colloid and Interface Science (2024), 663, 9-20. DOI:10.1016/j.jcis.2024.02.136

128. Falanga, Andrea Patrizia; Lupia, Antonio; Tripodi, Lorella; Morgillo, Carmine Marco; Moraca, Federica; Roviello, Giovanni Nicola; Catalanotti, Bruno; Amato, Jussara; Pastore, Lucio; Cerullo, Vincenzo; D'Errico, Stefano; Piccialli, Gennaro; Oliviero, Giorgia; Borbone, Nicola*

Exploring the DNA2-PNA heterotriplex formation in targeting the Bcl-2 gene promoter: A structural insight by physico-chemical and microsecond-scale MD investigation

From Heliyon (2024), 10, e24599. DOI:10.1016/j.heliyon.2024.e24599

127. Gallo, Enrico; Diaferia, Carlo; Giordano, Sabrina; Rosa, Elisabetta; Carrese, Barbara; Piccialli, Gennaro; Borbone, Nicola; Morelli, Giancarlo; Oliviero, Giorgia; Accardo, Antonella

Ultrashort Cationic Peptide Fmoc-FFK as Hydrogel Building Block for Potential Biomedical Applications

From Gels (2024), 10, 12. DOI:10.3390/gels10010012

126. Capasso, Domenica; Marino, Paola; Di Gaetano, Sonia; Borbone, Nicola; Terracciano, Monica; Trani, Roberta; Longo, Caterina; Piccialli, Vincenzo

Synthesis of Brominated Lactones Related to Mycalin A: Selective Antiproliferative Activity on Metastatic Melanoma Cells and Inhibition of the Cell Migration

From Marine Drugs (2023), 21, 349. DOI:10.3390/md21060349

125. Giordano, Sabrina; Gallo, Enrico; Diaferia, Carlo; Rosa, Elisabetta; Carrese, Barbara; Borbone, Nicola; Scognamiglio, Pasqualina Liana; Franzese, Monica; Oliviero, Giorgia; Accardo, Antonella

Multicomponent Peptide-Based Hydrogels Containing Chemical Functional Groups as Innovative Platforms for Biotechnological Applications

From Gels (2023), 9, 903. DOI:10.3390/gels9110903

124. Vicidomini, Caterina; Borbone, Nicola; Roviello, Valentina; Roviello, Giovanni Nicola; Oliviero, Giorgia

Summary of the Current Status of DNA Vaccination for Alzheimer Disease

From Vaccines (2023), 11, 1706. DOI:10.3390/ vaccines11111706

123. Piccialli, Ilaria; Greco, Francesca; Roviello, Giovanni N.; Sisalli, Maria J.; Tedeschi, Valentina; di Mola, Antonia; Borbone, Nicola; Oliviero, Giorgia; De Feo, Vincenzo; Secondo, Agnese; Massa, Antonio; Pannaccione, Anna

The 3-(3-oxoisoindolin-1-yl)pentane-2,4-dione (ISOAC1) as a new molecule able to inhibit Amyloid β aggregation and neurotoxicity

From Biomedicine & Pharmacotherapy (2023), 168, 115745. DOI:10.1016/j.biopha.2023.115745

122. Marzano, Maria; D'Errico, Stefano; Greco, Francesca; Falanga, Andrea Patrizia; Terracciano, Monica; Di Prisco, Daria; Piccialli, Gennaro; Borbone, Nicola*; Oliviero, Giorgia

Polymorphism of G-quadruplex formed by short oligonucleotides containing a 3'-3' inversion of polarity: From G:C:G:C tetrads to π-π stacked G-wires

From International Journal of Biological Macromolecules (2023), 253, 127062. DOI:10.1016/j.ijbiomac.2023.127062

121. Terracciano, Monica; Račkauskas, S.; Falanga, Andrea Patrizia; Martino, Sara; Chianese, Giovanna; Greco, Francesca; Piccialli, Gennaro; Viscardi, Guido; De Stefano, Luca; Oliviero, Giorgia; Borbone, Nicola*; Rea, Ilaria

ZnO Tetrapods for Label-Free Optical Biosensing: Physicochemical Characterization and Functionalization Strategies

From International Journal of Molecular Sciences (2023), 24, 4449. DOI:10.3390/ijms24054449

120. D'Errico, Stefano; Falanga Andrea Patrizia; Greco, Francesca; Piccialli, Gennaro; Oliviero, Giorgia; Borbone, Nicola

State of Art in the Chemistry of Nucleoside-Based Pt(II) Complexes

From Bioorganic Chemistry (2023), 131,106325. DOI:10.1016/j.bioorg.2022.106325

119. Tramontano, Chiara; Martins, João P.; De Stefano, Luca; Kemell, Marianna; Terracciano, Monica; Borbone, Nicola; Rea, Ilaria; Santos, Hélder Almeida

Microfluidic-assisted production of gastro-resistant active-targeted diatomite nanoparticles for the local release of galunisertib in metastatic colorectal cancer cells

From Advanced Healthcare Materials (2023), 12, 2202672. DOI:10.1002/adhm.202202672

118. Terracciano, Monica; Fontana, Flavia; Falanga, Andrea P.; D'Errico, Stefano; Torrieri, Giulia; Greco, Francesca; Tramontano, Chiara; Rea, Ilaria; Piccialli, Gennaro; De Stefano, Luca; Oliviero, Giorgia; Santos, Hélder A.; Borbone, Nicola

Development of surface chemical strategies for synthesizing redox-responsive diatomite nanoparticles as a green platform for on-demand intracellular release of an antisense peptide nucleic acid anticancer agent

From Small (2022), 18(41), 2204732. DOI:10.1002/smll.202204732

117. Falanga, Andrea P.; Terracciano, Monica; Oliviero, Giorgia; Roviello, Giovanni N.; Borbone, Nicola

Exploring the relationship between G-quadruplex nucleic acids and plants: from plant G-quadruplex function to phytochemical G4 ligands with pharmaceutic potential

From Pharmaceutics (2022), 14(11), 2377. DOI:10.3390/pharmaceutics14112377

116. Greco, Francesca; Musumeci, Domenica; Borbone, Nicola; Falanga, Andrea P.; D'Errico, Stefano; Terracciano, Monica; Piccialli, Ilaria; Roviello, Giovanni N.; Oliviero, Giorgia

Exploring the parallel G-quadruplex nucleic acid world: a spectroscopic and computational investigation on the binding of the c-myc ongogene NHE III1 region by the phytochemical polydatin

From Molecules (2022), 27(9), 2997. DOI:10.3390/molecules27092997

115. Greco, Francesca; Marzano, Maria; Falanga, Andrea P.; Terracciano, Monica; Piccialli, Gennaro; Roviello, Giovanni N.; D’Errico, Stefano; Borbone, Nicola; Oliviero, Giorgia

Cytosine-rich oligonucleotides incorporating a non-nucleotide loop: a further step towards the obtainment of physiologically stable i-motif DNA

From International Journal of Biological Macromolecules (2022), 219, 626-636. DOI:10.1016/j.ijbiomac.2022.08.016 

114. Greco, Francesca; Marzano, Maria; Falanga, Andrea P.; Terracciano, Monica; D’Ambrosio, Carlotta; Piccialli, Gennaro; Oliviero, Giorgia; Roviello, Giovanni N.; Borbone, Nicola

CD, UV, and In Silico Insights on the Effect of 1,3-Bis(10-uracilyl)-2-propanone on Serum Albumin Structure

From Biomolecules (2022), 12, 1071. DOI:10.3390/biom12081071

113. Borbone, Nicola; Piccialli, Ilaria; Falanga, Andrea P.; Piccialli, Vincenzo; Roviello, Giovanni, N.; Oliviero, Giorgia

Nucleic Acids as Biotools at the Interface between Chemistry and Nanomedicine in the COVID-19 Era

From International Journal of Molecular Sciences (2022), 23, 4359. DOI:10.3390/ijms23084359

112. Cesaro, Elena; Falanga, Andrea P.; Catapano, Rosa.; Greco, Francesca; Romano, Simona; Borbone, Nicola; Pastore, Arianna; Marzano, Maria; Chiurazzi, F.; D'Errico, Stefano; Piccialli, Gennaro; Oliviero, Giorgia; Costanzo, Paola; Grosso, Michela

Exploring a peptide nucleic acid-based antisense approach for CD5 targeting in chronic lymphocytic leukemia

From Plos One (2022), 17, e0266090. DOI:10.1371/journal.pone.0266090

111. Marzano, Maria; Borbone, Nicola; Amato, Felice; Oliviero, Giorgia; Fucile, Pierpaolo; Russo, Teresa; Sannino, Filomena

3D Chitossan-Gallic Acid Complexes: Assessment of the Chemical and Biological Properties

From Gels (2022), 8, 124. DOI:10.3390/gels8020124

110. Mironov, Vladimir.; Shchugoreva, Irina A.; Artyushenko, Polina V.; Morozov, Dmitry; Borbone, Nicola; Oliviero, Giorgia; Zamay, Tatiana N. et al.

Structure and Interaction Based Design of Anti-SARS-CoV-2 Aptamers

From Chemistry A European Journal (2022), 28, e202104481. DOI:10.1002/chem.202104481

109. D'Errico, Stefano; Greco, Francesca; Falanga Andrea P.; Tedeschi, Valentina; Piccialli, Ilaria; Marzano, Maria; Terracciano, Monica; Secondo, Agnese; Roviello, Giovanni N.; Oliviero, Giorgia; Borbone, Nicola

Probing the Ca2+ Mobilizing Properties on Primary Cortical Neurons of a New Stable cADPR Mimic

From Bioorganic Chemistry (2021), 117, 105401. DOI:10.1016/j.bioorg.2021.105401

108. Rea, Ilaria; Dardano, Principia; Moretta, Rosalba; Schiattarella, Chiara; Terracciano, Monica; Casalino, Maurizio; Gioffrè, Mariano; Crisci, Teresa; Chianese, Giovanna; Tramontano, Chiara; Borbone, Nicola; De Stefano, Luca

Hybrid Organic/Inorganic Nanomaterials for Biochemical Sensing

From Lecture Notes in Electrical Engineering (2021), 753, 93–99. DOI:10.1007/978-3-030-69551-4_13

107. Comegna, Marika; Conte, Gemma; Falanga, Andrea P.; Marzano, Maria; Cernera, Gustavo; Di Lullo, Antonella M.; Amato, Felice; Borbone, Nicola; D'Errico, Stefano; Ungaro, Francesca; d'Angelo, Ivana; Oliviero, Giorgia

Assisting PNA transport through cystic fibrosis human airway epithelia with biodegradable hybrid lipid-polymer nanoparticles

From Scientific Reports (2021), 11, Article number 6393. DOI:10.1038/s41598-021-85549-z

106. Galica, Tomas; Borbone, Nicola; Mares, Jan; Kust,, Andreja; Caso, Alessia; Esposito, Germana; Saurav, Kumar; Hajek, Jan; Rehakova, Klara; Urajova, Petra; Costantino, Valeria; Hrouzek, Pavel

Cyanochelins, an overlooked class of widely distributed cyanobacterial siderophores, discovered by silent gene cluster awakening

From Applied and Environmental Microbiology (2021), 87, Article number e0312820. DOI:10.1128/AEM.03128-20

105. Artyushenko, Polina V.; Mironov, Vladimir A.; Morozov, Dmitry I.; Shchugoreva, Irina A.; Borbone, Nicola; Tomilin, F.N.; Kichkailo, Anna S.

Computational approach to design of aptamers to the receptor binding domain of SARS-CoV-2

From Siberian Medical Review (2021), 2021, 66-67. DOI:10.20333/2500136-2021-2-66-67

104. Crisci, Teresa; Falanga, Andrea P.; Casalino, Maurizio; Borbone, Nicola; Terracciano, Monica; Chianese, Giovanna; Gioffrè, Mariano; D'Errico, Stefano; Marzano, Maria; Rea, Ilaria; De Stefano, Luca; Oliviero, Giorgia

Bioconjugation of a PNA probe to zinc oxide nanowires for label-free sensing

From Nanomaterials (2021), 11, 523. DOI:10.3390/nano11020523

103. Borbone, Nicola; Piccialli, Gennaro; Roviello, Giovanni N.; Oliviero, Giorgia

Nucleoside Analogs and Nucleoside Precursors as Drugs in the Fight against SARS-CoV-2 and Other Coronaviruses

From Molecules (2021), 26, 986. DOI:10.3390/molecules26040986

102. Moretta, Rosalba; Terracciano, Monica; Borbone, Nicola; Oliviero, Giorgia; Schiattarella, Chiara; Piccialli, Gennaro; Falanga, Andrea P.; Marzano, Maria; Dardano, Principia; De Stefano, Luca; Rea, Ilaria

PNA-based graphene oxide/porous silicon hybrid biosensor: Towards a label-free optical assay for brugada syndrome

From Nanomaterials (2020), 10, 2233. DOI:10.3390/nano10112233

101. Marzano, Maria; Falanga, Andrea P.; Dardano, Principia; D'Errico, Stefano; Rea, Ilaria; Terracciano, Monica; De Stefano, Luca; Piccialli, Gennaro; Borbone, Nicola; Oliviero, Giorgia

π–π stacked DNA G-wire nanostructures formed by a short G-rich oligonucleotide containing a 3′–3′ inversion of polarity site

From Organic Chemistry Frontiers (2020), 7, 2187–2195. DOI:10.1039/D0QO00561D

100. D'Errico, Stefano; Falanga, Andrea P.; Capasso, Domenica; Di Gaetano, Sonia; Marzano, Maria; Terracciano, Monica; Roviello, Giovanni N.; Piccialli, Gennaro; Oliviero, Giorgia; Borbone, Nicola

Probing the DNA reactivity and the anticancer properties of a novel tubercidin-Pt(II) complex

From Pharmaceutics (2020), 12(7), 627. DOI:10.3390/pharmaceutics12070627

99. Saurav, Kumar; Borbone, Nicola; Burgsdorf, Ilia; Teta, Roberta; Caso, Alessia; Bar-Shalom, Rinat; Esposito, Germana; Britstein, Maya; Steindler, Laura; Costantino, Valeria

Identification of quorum sensing activators and inhibitors in the marine sponge Sarcotragus spinosulus

From Marine Drugs (2020), 18(2), 127. DOI: 10.3390/md18020127

98. Gangemi, Chiara M. A.; Alaimo, Salvatore; Pulvirenti, Alfredo; García-Viñuales, Sara; Milardi, Demetrio; Falanga, Andrea P.; Fragalà, Maria E.; Oliviero, Giorgia; Piccialli, Gennaro; Borbone, Nicola; Ferro, Alfredo; D'Urso, Alessandro; Croce, Carlo M.; Purrello, Roberto

Endogenous and artificial miRNAs explore a rich variety of conformations: a potential relationship between secondary structure and biological functionality

From Scientific Reports (2020), 10(1), 453. DOI: 10.1038/s41598-019-57289-8

97. Marzano, Maria; Falanga, Andrea P.; Marasco, Daniela; Borbone, Nicola; D'Errico, Stefano; Piccialli, Gennaro; Roviello, Giovanni N.; Oliviero, Giorgia

Evaluation of an Analogue of the Marine ε-PLL Peptide as a Ligand of G-quadruplex DNA Structures

From Marine Drugs (2020), 18(1), 49. DOI: 10.3390/md18010049

96. Roviello, Giovanni N.; Oliviero, Giorgia; Di Napoli, Antonella; Borbone, Nicola; Piccialli, Gennaro

Synthesis, self-assembly-behavior and biomolecular recognition properties of thyminyl dipeptides

From Arabian Journal of Chemistry (2020), 13(1), 1966–1974. DOI: 10.1016/j.arabjc.2018.02.014

95. D'Errico, Stefano; Basso, Emy; Falanga, Andrea P.; Marzano, Maria; Pozzan, Tullio; Piccialli, Vincenzo; Piccialli, Gennaro; Oliviero, Giorgia; Borbone, Nicola

New Linear Precursors of cIDPR Derivatives as Stable Analogs of cADPR: A Potent Second Messenger with Ca2+-Modulating Activity Isolated from Sea Urchin Eggs

From Marine Drugs (2019), 17(8), 476. DOI:10.3390/md17080476

94. Marzano, Maria; Falanga, Andrea P.; D’Errico, Stefano; Pinto, Brunella; Roviello, Giovanni; Piccialli, Gennaro; Oliviero, Giorgia; Borbone, Nicola

New G-quadruplex-forming oligodeoxynucleotides incorporating a bifunctional Double-Ended Linker (DEL): effects of DEL size and ODNs orientation on the topology, stability and molecularity of DEL-G-quadruplexes

From Molecules (2019), 24(3), 654. DOI:10.3390/molecules24030654

93. Falanga, Andrea P.; Cerullo, Vincenzo; Marzano, Maria; Feola, Sara; Oliviero, Giorgia; Piccialli, Gennaro; Borbone, Nicola

Peptide Nucleic Acid-Functionalized Adenoviral Vectors Targeting G-Quadruplexes in the P1 Promoter of Bcl-2 Proto-Oncogene: A New Tool for Gene Modulation in Anticancer Therapy

From Bioconjugate Chemistry (2019), 30(3), 572–582. DOI:10.1021/acs.bioconjchem.8b00674

92. Terracciano, Monica; Rea, Ilaria; Borbone, Nicola; Moretta, Rosalba; Oliviero, Giorgia; Piccialli, Gennaro; De Stefano, Luca

Porous Silicon-Based Aptasensors: The Next Generation of Label-Free Devices for Health Monitoring

From Molecules (2019), 24(12), 2216. DOI:10.3390/molecules24122216

91. Falanga, Andrea P.; Melone, Pietro; Cagliani, Roberta; Borbone, Nicola; D’Errico, Stefano; Piccialli, Gennaro; Netti, Paolo A.; Guarnieri, Daniela

Design, Synthesis and Characterization of Novel Co-Polymers Decorated with Peptides for the Selective Nanoparticle Transport across the Cerebral Endothelium

From Molecules (2018), 23(7), 1655. DOI:10.3390/molecules23071655

90. D’Errico, Stefano; Borbone, Nicola; Catalanotti, Bruno; Secondo, Agnese; Petrozziello,Tiziana; Piccialli, Ilaria; Pannaccione, Anna; Costantino, Valeria; Mayol, Luciano; Piccialli, Gennaro; Oliviero, Giorgia

Synthesis and biological evaluation of a new structural simplified analogue of cADPR, a calcium-mobilizing secondary messenger firstly isolated from sea urchin eggs

From Marine Drugs (2018), 16(3), 89. DOI:10.3390/md16030089

89. Nici, Fabrizia; Oliviero, Giorgia; Falanga, Andrea Patrizia; D’Errico, Stefano; Marzano, Maria; Musumeci, Domenica; Montesarchio, Daniela; Noppen, Sam; Pannecouque, Christophe; Piccialli, Gennaro; Borbone, Nicola

Anti-HIV activity of new higher-order G-quadruplex aptamers obtained from tetra-end-linked oligonucleotides

From Organic & Biomolecular Chemistry (2018), 16(13), 2349–2355. DOI:10.1039/C7OB02346D

88. D’Errico, Stefano; Borbone, Nicola; Piccialli, Vincenzo; Di Gennaro, Elena; Zotti, Andrea; Budillon, Alfredo; Vitagliano, Carlo; Piccialli, Ilaria; Oliviero, Giorgia

Synthesis and evaluation of the antitumor properties of a small collection of PtII complexes with 7-deazaadenosine as scaffold

From European Journal of Organic Chemistry (2017), 4935–4947. DOI:10.1002/ejoc.201700730

87. D’Urso, Alessandro; Randazzo, Rosalba; Rizzo, V; Gangemi, C.M.A.; Romanucci, Valeria; Zarrelli, A.; Tomaselli, G.; Milardi, D.; Borbone, Nicola; Purrello, Roberto; Piccialli, Gennaro; Di Fabio, Giovanni; Oliviero, Giorgia 

Stabilization vs. destabilization of G-quadruplex superstructures: the role of the porphyrin derivative having spermine arms

From Physical Chemistry Chemical Physics (2017), 19, 17404–17410. DOI:10.1039/c7cp02816d

86. Zarrilli, Federica; Amato, Felice; Morgillo, Carmine Marco; Pinto, Brunella; Santarpia, Giuliano; Borbone, Nicola; D’Errico, Stefano; Catalanotti, Bruno; Piccialli, Gennaro; Castaldo, Giuseppe; Oliviero, Giorgia

Peptide nucleic acids as miRNA target protectors for the treatment of cystic fibrosis

From Molecules (2017), 22, 1144. DOI:10.3390/molecules22071144

85. Oliviero, Giorgia; D’Errico, Stefano; Pinto, Brunella; Nici, Fabrizia; Dardano, Principia; Rea, Ilaria; De Stefano, Luca; Mayol, Luciano; Piccialli, Gennaro; Borbone, Nicola 

Self-assembly of G-rich oligonucleotides incorporationg a 3’-3’ inversion of polarity site: a new route towards G-wire DNA nanostructures

From ChemistryOpen (2017), 6, 599–605. DOI:10.1002/open.201700024

84. Pinto, Brunella; Rusciano, Giulia; D’Errico, Stefano; Borbone, Nicola; Sasso, Antonio; Piccialli, Vincenzo; Mayol, Luciano; Oliviero, Giorgia; Piccialli, Gennaro

Synthesis and label free characterization of a bimolecular PNA homo quadruplex

From BBA General Subjects (2017), 1861, 1222–1228. DOI:10.1016/j.bbagen.2016.11.037

83. Zaccaria, Sabrina; Borbone, Nicola; Oliviero, Giorgia; D’Errico, Stefano; Piccialli, Vincenzo

Pyridinium chlorochromate chemistry. New insight into oxidation of tetrahydrofurans

From Arkivoc (2017), part iv, 273–290. DOI:10.3998/ark.5550190.p010.063

82. Piccialli, Vincenzo; Borbone, Nicola; Oliviero, Giorgia; Piccialli, Gennaro; D’Errico, Stefano; Centore, Roberto 

5-Amino-1-(2′,3′-O-iso­propyl­idene-D-ribit­yl)-1H-imidazole-4-carboxamide: a crystal structure with Z′ = 4

From Acta Crystallographica Section E (2017), E73, 183–187. DOI:10.1107/S2056989017000500

81. Scudiero, Olga; Nigro, Ersilia; Monaco, Maria Ludovica; Oliviero, Giorgia; Polito, Rita; Borbone, Nicola; D’Errico, Stefano; Mayol, Luciano; Daniele, Aurora; Piccialli, Gennaro 

New synthetic AICAR derivatives with enhanced AMPK and ACC activation

From Journal of Enzyme Inhibition and Medicinal Chemistry (2016), 31, 748–753. DOI:10.3109/14756366.2015.1063622

80. Terracciano, Monica; De Stefano, Luca; Borbone, Nicola; Politi, Jane; Oliviero, Giorgia; Nici, Fabrizia; Casalino, Maurizio; Piccialli, Gennaro; Dardano, Principia; Varra, Michela; Rea, Ilaria

Solid phase synthesis of thrombin binding aptamer on macroporous silica for label free optical quantification of thrombin

From RSC Advances (2016), 6, 86762–86769. DOI:10.1039/C6RA18401D

79. Barone, Roberto; de Biasi, Margherita-Gabriella; Piccialli, Vincenzo; de Napoli, Lorenzo; Oliviero, Giorgia; Borbone, Nicola; Piccialli, Gennaro

Degradation of some representative polycyclic aromatic hydrocarbons by the water-soluble protein extracts from Zea mays L. cv PR32-B10

From Chemosphere (2016), 160, 258–265. DOI:10.1016/j.chemosphere.2016.06.069

78. Politi, Jane; Rea, Ilaria; Nici, Farbrizia; Dardano, Principia; Terracciano, Monica; Oliviero, Giorgia; Borbone, Nicola; Piccialli, Gennaro; De Stefano, Luca

Nanogravimetric and optical characterization of thrombin interaction with a self-assembled thiolated aptamer

From Journal of Sensors (2016), Article ID 3561863, 8 pages. DOI:10.1155/2016/3561863

77. Oliviero, Giorgia; Stornaiuolo, Mariano; D’Atri, Valentina; Nici, Fabrizia; Yousif, Ali Munaim; D’Errico, Stefano; Piccialli, Gennaro; Mayol, Luciano; Novellino, Ettore; Marinelli, Luciana; Grieco, Paolo; Carotenuto, Alfonso; Noppen, Sam; Liekens, Sandra; Balzarini, Jan; Borbone, Nicola 

Screening platform toward new anti-HIV aptamers set on molecular docking and fluorescence quenching techniques

From Analytical Chemistry (2016), 88, 2327–2334. DOI:10.1021/acs.analchem.5b04268

76. D’Errico, Stefano; Oliviero, Giorgia; Borbone, Nicola; Piccialli, Vincenzo; Piccialli, Gennaro

Synthesis of 5-aminoimidazole-4-carboxamide riboside (AICAR) and its derivatives using inosine as starting material

From Current Protocols in Nucleic Acid Chemistry (2015), 63, 1.35.1–1.35.24. DOI:10.1002/0471142700.nc0135s63

75. Mahal, A.; D’Errico, Stefano; Borbone, Nicola; Pinto, Brunella; Secondo, Agnese; Costantino, Valeria; Tedeschi, Valentina; Oliviero, Giorgia; Piccialli, Vincenzo; Piccialli, Gennaro

Synthesis of cyclic N1-pentylinosine phosphate, a new structurally reduced cADPR analogue with calcium-mobilizing activity on PC12 cells

From Beilstein Journal of Organic Chemistry (2015), 11, 2689-2695. DOI:10.3762/bjoc.11.289

74. D'Errico, Stefano; Oliviero, Giorgia; Borbone, Nicola; Di Gennaro, Elena; Zotti, Andrea Ilaria; Budillon, Alfredo; Cerullo, Vincenzo; Nici, Fabrizia; Mayol, Luciano; Piccialli, Vincenzo; Piccialli, Gennaro

Synthesis and evaluation of the anti proliferative properties of a new tethered tubercidin-platinum(II) complex

From European Journal of Organic Chemistry (2015), 7550-7556. DOI:10.1002/ejoc.201500998

73. Scuotto, Maria; Rivieccio, Elisa; Varone, Alessia; Corda, Daniela; Bucci, Mariarosaria; Vellico, Valentina; Cirino, Giuseppe; Virgilio, Antonella; Esposito, Veronica; Galeone, Aldo; Borbone, Nicola; Varra, Michela, Mayol, Luciano

Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to anti proliferative

From Nucleic Acid Research (2015), 43, 7702-7716. DOI:10.1093/nar/gkv789

72. D'Errico, Stefano; Oliviero, Giorgia; Borbone, Nicola; Nici, Fabrizia; Piccialli, Vincenzo; Pinto, Brunella; D'Alonzo, Daniele; Mayol, Luciano; Piccialli, Gennaro

Synthesis of C6-Pyridinil Purine Nucleosides by Reaction of Nebularine N1-Oxide with Pyridinil Grignard's Reagents

From European Journal of Organic Chemistry (2015), 10, 2244-2249. DOI:10.1002/ejoc.201403648

71. Garofalo, Mariangela; Iovene, Barbara; Orefice, Maria; Kuryk, L.; Hirvinen, M.; Capasso, Cristian; Romanyuk, D.; Cerullo, Vincenzo; Oliviero, Giorgia; Borbone, Nicola; Piccialli, Gennaro; Bevilacqua, Maria A

Oncolytic adenovirus loaded with L-carnosine as a drug delivery system for cancer therapy

From FEBS Journal (2014), 281, 587–588. DOI:10.1111/febs.12919 

70. D'Errico, Stefano; Oliviero, Giorgia; Borbone, Nicola; Piccialli, Vincenzo; Pinto, Brunella; De Falco, Francesca; Maiuri, Maria Chiara; Carnuccio, Rosa; Costantino, Valeria; Nici, Fabrizia; Piccialli, Gennaro

Synthesis and pharmacological evaluation of modified adenosines joined to mono-functional platinum moieties

From Molecules (2014), 19(7), 9339-9353. DOI:10.3390/molecules19079339

69. Terracciano, Monica; Rea, Ilaria; De Stefano, Luca; Rendina, Ivo; Oliviero, Giorgia; Nici, Fabrizia; D'Errico, Stefano; Piccialli, Gennaro; Borbone, Nicola

Synthesis of mixed-sequence oligonucleotides on mesoporous silicon: chemical strategies and material stability

From Nanoscale Research Letters (2014), 9(1), 317. DOI:10.1186/1556-276X-9-317

68. Scuotto, Maria; Persico, Marco; Bucci, Maria Rosaria; Vellecco, Valentina; Borbone, Nicola; Morelli, Elena; Oliviero, Giorgia; Novellino, Ettore; Piccialli, Gennaro; Cirino, Giuseppe; Varra, Michela; Fattorusso, Caterina; Mayol, Luciano

Outstanding effects on antithrombin activity of modified TBA diastereomers containing an optically pure acyclic nucleotide analogue

From Organic & Biomolecular Chemistry (2014), 12, 5235-5242. DOI:10.1039/C4OB00149D

67. Iovine, Barbara; Oliviero, Giorgia; Garofalo, Mariangela; Orefice, Maria; Nocella, Francesca; Borbone, Nicola; Piccialli, Vincenzo; Centore, Roberto; Mazzone, Massimiliano; Piccialli, Gennaro; Bevilacqua, Mariassunta

The antiproliferative effect of L-carnosine correlates with a decreased expression of Hypoxia Inducible Factor 1 alpha in human colon cancer cells

From PLOS ONE (2014), 9(5), e96755, 10 pages. DOI:10.1371/journal.pone.0096755

66. Amato, Felice; Tomaiuolo, Rossella; Nici, Fabrizia; Borbone, Nicola; Elce, Ausilia; Catalanotti, Bruno; D'Errico , Stefano; Morgillo, Carmine Marco; De Rosa, Giuseppe; Mayol, Laura; Piccialli, Gennaro; Oliviero, Giorgia; Castaldo, Giuseppe

Exploitation of a very small peptide nucleic acid as a new inhibitor of miR-509-3p involved in the regulation of cystic fibrosis disease-gene expression

From BioMed Research International (2014), vol 2014, Article ID 610718, 10 pages. DOI:10.1155/2014/610718

65. D'Atri, Valentina; Borbone, Nicola; Amato, Jussara; Gabelica, Valérie; D'Errico, Stefano; Piccialli, Gennaro; Mayol, Luciano; Oliviero, Giorgia 

DNA-based nanostructures: the effect of the base sequence on octamer formation from d(XGGYGGT) tetramolecular G-quadruplexes

From Biochimie (2014), 99, 119-128. DOI:10.1016/j.biochi.2013.11.020

64. Amato, Felice; Tomaiuolo, Rossella; Borbone, Nicola; Elce, Ausilia; Amato, Jussara; D'Errico, Stefano; De Rosa, Giuseppe; Mayol, Laura; Piccialli, Gennaro; Oliviero, Giorgia; Castaldo, Giuseppe

Design, synthesis and biochemical investigation, by in vitro luciferase reporter system, of peptide nucleic acids as new inhibitors of miR-509-3p involved in the regulation of cystic fibrosis disease-gene expression

From Medicinal Chemistry Communications (2014), 5, 68–71. DOI:10.1039/C3MD00257H

63. Amato, Jussara; Stellato, Marco Ignazio; Pizzo, Elio; Petraccone, Luigi; Oliviero, Giorgia; Borbone, Nicola; Piccialli, Gennaro; Orecchia, Angela; Bellei, Barbara; Castiglia, Daniele; Giancola, Concetta 

PNA as potential modulator of COL7A1 gene expression in dominant dystrophic epidermolysis bullosa: a physico-chemical study

From Molecular BioSystems (2013), 9, 3166-3174. DOI:10.1039/C3MB70283

62. D'Errico, Stefano; Oliviero, Giorgia; Borbone, Nicola; Piccialli, Vincenzo; D'Atri, Valentina; Mayol, Laura; Piccialli, Gennaro

Synthesis of 2,6-Dialkyl(aryl)purine Nucleosides by Exploiting the Reactivity of Nebularine N1-Oxide towards Grignard Reagents

From European Journal of Organic Chemistry (2013), 2013(30), 6948-6954. DOI:10.1002/ejoc.201300941

61. Piccialli, Vincenzo; Zaccaria, Sabrina; Borbone, Nicola; Centore, Roberto; Tuzi, Angela

(3R,3aR,6R,6aR)-Hexahydrofuro[3,2-b]- furan-3,6-diyl dibenzoate

From Acta Crystallographica Section E Structure Reports (2013), 69(9), o1396-o1397. DOI:10.1107/S1600536813021612

60. Piccialli, Vincenzo; Tuzi, Angela; Oliviero, Giorgia; Borbone, Nicola; Centore, Roberto 

3β,6α-Diacetoxy-5,9α-dihydroxy-5α-cholest-7-en-11-one

From Acta Crystallographica Section E Structure Reports (2013), 69(7), o1109-o1110. DOI:10.1107/S1600536813016206

59. Piccialli, Vincenzo; Oliviero, Giorgia; Borbone, Nicola; Centore, Roberto; Tuzi, Angela

3β,6β-Diacetoxy-5,9α-dihydroxy-5α-cholest-7-en-11-one acetic acid 0.04-solvate

From Acta Crystallographica Section E Structure Reports (2013), 69(6), o879-o880. DOI:10.1107/S1600536813012646

58. De Stefano, Luca; Oliviero, Giorgia; Amato, Jussara; Borbone, Nicola; Piccialli, Gennaro; Mayol, Luciano; Rendina, Ivo; Terracciano, Monica; Rea, Ilaria

Aminosilane functionalizations of mesoporous oxidized silicon for oligonucleotide synthesis and detection

From Journal of the Royal Society Interface (2013), 10(83), 20130160. DOI:10.1098/rsif.2013.0160

57. Piccialli, Vincenzo; D'Errico, Stefano; Borbone, Nicola; Oliviero, Giorgia; Centore, Roberto; Zaccaria, Sabrina

A General Synthesis of Bis alpha-Acyloxy-1,4- and 1,5-Diketones through Catalytic Oxidative Opening of Acylated THF and THP Diols

From European Journal of Organic Chemistry (2013), (9), 1781-1789. DOI:10.1002/ejoc.201201554

56. D'Errico, Stefano; Oliviero, Giorgia; Borbone, Nicola; Amato, Jussara; D'Alonzo, Daniele; Piccialli, Vincenzo; Mayol, Luciano; Piccialli, Gennaro

A facile synthesis of 5'-fluoro-5'-deoxyacadesine (5'-F-AICAR): a novel non-phosphorylable AICAR analogue

From Molecules (2012), 17, 13036-13044. DOI:10.3390/molecules171113036

55. Borbone, Nicola; Bucci, Mariarosaria; Oliviero, Giorgia; Morelli, Elena; Amato, Jussara; D'Atri, Valentina; D'Errico, Stefano; Vellecco, Valentina; Cirino, Giuseppe; Piccialli, Gennaro; Fattorusso, Caterina; Varra, Michela; Mayol, Luciano; Persico, Marco; Scuotto, Maria

Investigating the Role of T7 and T12 Residues on the Biological Properties of Thrombin-Binding Aptamer: Enhancement of Anticoagulant Activity by a Single Nucleobase Modification

From Journal of Medicinal Chemistry (2012), 55(23), 10716-10728. DOI:10.1021/jm301414f

54. D'Atri, Valentina; Oliviero, Giorgia; Amato, Jussara; Borbone, Nicola; D'Errico, Stefano; Mayol, Luciano; Piccialli, Vincenzo; Haider, Shozeb; Hoorelbeke, Bart; Balzarini, J; Piccialli, Gennaro

New anti-HIV aptamers based on tetra-end-linked DNA G-quadruplexes: effect of the base sequence on anti-HIV activity

From Chemical Communications (2012), 48(76), 9516-9518. DOI:10.1039/c2cc34399a

53. D'Errico, Stefano; Oliviero, Giorgia; Amato, Jussara; Borbone, Nicola; Cerullo, Vincenzo; Hemminki, Akseli; Piccialli, Vincenzo; Zaccaria, Sabrina; Mayol, Luciano; Piccialli, Gennaro

Synthesis and biological evaluation of unprecedented ring-expanded nucleosides (RENs) containing the imidazo[4,5-d][1,2,6]oxadiazepine ring system

From Chemical Communications (2012), 48(74), 9310-9312. DOI:10.1039/c2cc33511e

52. Piccialli, Vincenzo; Zaccaria, Sabrina; Oliviero, Giorgia; D'Errico, Stefano; D'Atri, Valentina; Borbone, Nicola

Insight into Pyridinium Chlorochromate Chemistry: Catalytic Oxidation of Tetrahydrofuran Compounds and Synthesis of Umbelactone

From European Journal of Organic Chemistry (2012), 2012(23), 4293-4305. DOI:10.1002/ejoc.201200069

51. Piccialli, Vincenzo; Zaccaria, Sabrina; Centore, Roberto; Tuzi, Angela; Borbone, Nicola; Oliviero, Giorgia; D'Errico, Stefano; D'Atri, Valentina

Insight Into the Conformational Arrangement of a Bis-THF Diol Compound Through 2D-NMR Studies and X-Ray Structural Analysis

From Journal of Chemical Crystallography (2012), 42(4), 360-365. DOI:10.1007/s10870-011-0254-9

50. D'Errico, Stefano; Oliviero, Giorgia; Borbone, Nicola; Amato, Jussara; Piccialli, Vincenzo; Varra, Michela; Mayol, Luciano; Piccialli, Gennaro

Solid-phase synthesis of a new diphosphate 5-aminoimidazole-4-carboxamide riboside (AICAR) derivative and studies toward cyclic AICAR diphosphate ribose

From Molecules (2011), 16, 8110-8118. DOI:10.3390/molecules16098110

49. Borbone, Nicola; Amato, Jussara; Oliviero, Giorgia; D'Atri, Valentina; Gabelica, Valerie; De Pauw, Edwin; Piccialli, Gennaro; Mayol, Luciano

d(CGGTGGT) forms an octameric parallel G-quadruplex via stacking of unusual G(:C):G(:C):G(:C):G(:C) octads

From Nucleic Acids Research (2011), 39(17), 7848-7857. DOI:10.1093/nar/gkr489

48. D'Errico, Stefano; Oliviero, Giorgia; Piccialli, Vincenzo; Amato, Jussara; Borbone, Nicola; D'Atri, Valentina; D'Alessio, Francesca; Di Noto, Rosa; Ruffo, Francesco; Salvatore, Francesco; et al

Solid-phase synthesis and pharmacological evaluation of novel nucleoside-tethered dinuclear platinum(II) complexes

From Bioorganic & Medicinal Chemistry Letters (2011), 21(19), 5835-5838. DOI:10.1016/j.bmcl.2011.07.104

47. Rusciano, Giulia; De Luca, Anna Chiara; Pesce, Giuseppe; Sasso, Antonio; Oliviero, Giorgia; Amato, Jussara; Borbone, Nicola; D'Errico, Stefano; Piccialli, Vincenzo; Piccialli, Gennaro; et al

Label-Free Probing of G-Quadruplex Formation by Surface-Enhanced Raman Scattering

From Analytical Chemistry (Washington, DC, United States) (2011), 83(17), 6849-6855. DOI:10.1021/ac201783h

46. D'Errico, Stefano; Piccialli, Vincenzo; Oliviero, Giorgia; Borbone, Nicola; Amato, Jussara; D'Atri, Valentina; Piccialli, Gennaro

Probing the reactivity of nebularine N1-oxide. A novel approach to C-6 C-substituted purine nucleosides

From Tetrahedron (2011), 67(34), 6138-6144. DOI:10.1016/j.tet.2011.06.080

45. Franceschin, Marco; Borbone, Nicola; Oliviero, Giorgia; Casagrande, Valentina; Scuotto, Maria; Coppola, Teresa; Borioni, Silvia; Mayol, Luciano; Ortaggi, Giancarlo; Bianco, Armandodoriano; et al

Synthesis of a Dibromoperylene Phosphoramidite Building Block and Its Incorporation at the 5' End of a G-Quadruplex Forming Oligonucleotide: Spectroscopic Properties and Structural Studies of the Resulting Dibromoperylene Conjugate

From Bioconjugate Chemistry (2011), 22(7), 1309-1319. DOI:10.1021/bc100526q

44. Piccialli, Vincenzo; Zaccaria, Sabrina; Centore, Roberto; Tuzi, Angela; Borbone, Nicola; Oliviero, Giorgia

Isolation of a bis-iodo tetra-THF as a trace product from the oxidation of squalene with RuO4 and its double ring expansion to a novel bis-THF-bis-THP compound

From Molecules (2011), 16, 5362-5373. DOI:10.3390/molecules16075362

43. Amato, Jussara; Pagano, Bruno; Borbone, Nicola; Oliviero, Giorgia; Gabelica, Valerie; De Pauw, Edwin; D'Errico, Stefano; Piccialli, Vincenzo; Varra, Michela; Giancola, Concetta; Piccialli, Gennaro; Mayol, Luciano

Targeting G-Quadruplex Structure in the Human c-Kit Promoter with Short PNA Sequences

From Bioconjugate Chemistry (2011), 22(4), 654-663. DOI:10.1021/bc100444v

42. Oliviero, Giorgia; Amato, Jussara; Borbone, Nicola; D'Errico, Stefano; Galeone, Aldo; Mayol, Luciano; Haider, Shozeb; Olubiyi, Olujide; Hoorelbeke, Bart; Balzarini, Jan; et al

Tetra-end-linked oligonucleotides forming DNA G-quadruplexes: a new class of aptamers showing anti-HIV activity

From Chemical Communications (2010), 46(47), 8971-8973. DOI:10.1039/c0cc02866e

41. Piccialli, Vincenzo; Zaccaria, Sabrina; Borbone, Nicola; Oliviero, Giorgia; D'Errico, Stefano; Hemminki, Akseli; Cerullo, Vincenzo; Romano, Valentina; Tuzi, Angela; Centore, Roberto

Discovery of a novel one-step RuO4-catalyzed tandem oxidative polycyclization/double spiroketalization process. Access to a new type of polyether bis-spiroketal compound displaying antitumor activity

From Tetrahedron (2010), 66(48), 9370-9378. DOI:10.1016/j.tet.2010.10.004

40. Oliviero, Giorgia; D'Errico, Stefano; Borbone, Nicola; Amato, Jussara; Piccialli, Vincenzo; Piccialli, Gennaro; Mayol, Luciano

Facile Solid-Phase Synthesis of AICAR 5'-Monophosphate (ZMP) and Its 4-N-Alkyl Derivatives

From European Journal of Organic Chemistry (2010), (8), 1517-1524, S1517/1-S1517/9. DOI:10.1002/ejoc.200901271

39. Oliviero, Giorgia; D'Errico, Stefano; Borbone, Nicola; Amato, Jussara; Piccialli, Vincenzo; Varra, Michela; Piccialli, Gennaro; Mayol, Luciano

A solid-phase approach to the synthesis of N-1-alkyl analogs of cyclic inosine-diphosphate-ribose (cIDPR)

From Tetrahedron (2010), 66(10), 1931-1936. DOI:10.1016/j.tet.2010.01.013

38. Rea, Ilaria; Oliviero, Giorgia; Amato, Jussara; Borbone, Nicola; Piccialli, Gennaro; Rendina, Ivo; De Stefano, Luca

Direct Synthesis of Oligonucleotides on Nanostructured Silica Multilayers

From Journal of Physical Chemistry C (2010), 114(6), 2617-2621. DOI:10.1021/jp908440u

37. Piccialli, Vincenzo; Oliviero, Giorgia; Borbone, Nicola; Tuzi, Angela; Centore, Roberto; Hemminki, Akseli; Ugolini, Matteo; Cerullo, Vincenzo

Discovery of a new PCC-mediated stereoselective oxidative spiroketalization process. An access to a new type of poly-THF spiroketal compound displaying anticancer activity

From Organic & Biomolecular Chemistry (2009), 7(15), 3036-3039. DOI:10.1039/b906872d

36. Oliviero, Giorgia; Borbone, Nicola; Amato, Jussara; D'Errico, Stefano; Galeone, Aldo; Piccialli, Gennaro; Varra, Michela; Mayol, Luciano

Synthesis of quadruplex-forming tetra-end-linked oligonucleotides: effects of the linker size on quadruplex topology and stability

From Biopolymers (2009), 91(6), 466-477. DOI:10.1002/bip.21153

35. Borrelli Francesca; Borbone Nicola; Capasso Raffaele; Montesano Domenico; De Marino Simona; Aviello Gabriella; Aprea Giovanni; Masone Stefania; Izzo Angelo A

Potent relaxant effect of a Celastrus paniculatus extract in the rat and human ileum

From Journal of ethnopharmacology (2009), 122(3), 434-438. DOI:10.1016/j.jep.2009.02.003

34. Piccialli, Vincenzo; Borbone, Nicola; Oliviero, Giorgia

RuO4-catalyzed oxidative polycyclization of the Cs-symmetric isoprenoid polyene digeranyl. An unexpected stereochemical outcome

From Tetrahedron (2008), 64(49), 11185-11192. DOI:10.1016/j.tet.2008.09.052

33. De Stefano, Luca; De Tommasi, Edoardo; Rea, Ilaria; Rotiroti, Lucia; Giangrande, Luca; Oliviero, Giorgia; Borbone, Nicola; Galeone, Aldo; Piccialli, Gennaro

Oligonucleotide direct synthesis on porous silicon chip

From Nucleic Acids Symposium Series (2008), 52(1), 721-722. DOI:10.1093/nass/nrn364

32. Oliviero, Giorgia; D'Errico, Stefano; Borbone, Nicola; Amato, Jussara; Piccialli, Vincenzo; Varra, Michela; Piccialli, Gennaro; Mayol, Luciano

Synthesis of N-1-alkyl analogues of cyclic inosine diphosphate ribose (cIDPR) by a new solid phase approach

From Nucleic Acids Symposium Series (2008), 52(1), 573-574. DOI:10.1093/nass/nrn290

31. Amato, Jussara; Gabelica, Valerie; Borbone, Nicola; Rosu, Frederic; De Pauw, Edwin; Oliviero, Giorgia; Piccialli, Gennaro; Mayol, Luciano

A short C-rich PNA fragment capable to form novel G-quadruplex-PNA complexes

From Nucleic Acids Symposium Series (2008), 52(1), 167-168. DOI:10.1093/nass/nrn085

30. Amato, Jussara; Oliviero, Giorgia; Borbone, Nicola; D'Errico, Stefano; Piccialli, Gennaro; Mailliet, Patrick; Rosu, Frederic; De Pauw, Edwin; Gabelica, Valerie

Ligand binding to tetra-end-linked (TGGGGT)4 G-quadruplexes: an electrospray mass spectroscopy study

From Nucleic Acids Symposium Series (2008), 52(1), 165-166. DOI:10.1093/nass/nrn084

29. Coppola, Teresa; Varra, Michela; Oliviero, Giorgia; Galeone, Aldo; D'Isa, Giuliana; Mayol, Luciano; Morelli, Elena; Bucci, Maria-Rosaria; Vellecco, Valentina; Cirino, Giuseppe; Borbone, Nicola

Synthesis, structural studies and biological properties of new TBA analogues containing an acyclic nucleotide

From Bioorganic & Medicinal Chemistry (2008), 16(17), 8244-8253. DOI:10.1016/j.bmc.2008.07.040

28. Oliviero, Giorgia; Amato, Jussara; Borbone, Nicola; D'Errico, Stefano; Piccialli, Gennaro; Mayol, Luciano

Solid-phase synthesis development of N1-alkyl analogues of cyclic inosine-diphosphate-ribose (cIDPR)

From Collection Symposium Series (2008), 10(Chemistry of Nucleic Acid Components), 330-332. DOI:10.1135/css200810330

27. Oliviero, Giorgia; Amato, Jussara; Borbone, Nicola; D'Errico, Stefano; Piccialli, Gennaro; Bucci, Enrico; Piccialli, Vincenzo; Mayol, Luciano

Synthesis of 4-N-alkyl and ribose-modified AICAR analogs on solid support

From Tetrahedron (2008), 64(27), 6475-6481. DOI:10.1016/j.tet.2008.04.071

26. Borbone, Nicola; Oliviero, Giorgia; Amato, Jussara; D'Errico, Stefano; Galeone, Aldo; Piccialli, Gennaro; Mayol, Luciano

Synthesis and Characterization of Tetra-End Linked Oligonucleotides Capable of Forming Monomolecular G-Quadruplexes

From Nucleosides, Nucleotides & Nucleic Acids (2007), 26(10-12), 1231-1236. DOI:10.1080/15257770701528172

25. Oliviero, Giorgia; Borbone, Nicola; Amato, Jussara; D'Errico, Stefano; Piccialli, Gennaro; Varra, Michela; Mayol, Luciano

Synthesis of A New Ribose Modified Analogue of Cyclic Inosine Diphosphate Ribose

From Nucleosides, Nucleotides & Nucleic Acids (2007), 26(10-12), 1321-1324. DOI:10.1080/15257770701530699

24. Borbone, Nicola; Oliviero, Giorgia; Amato, Jussara; Piccialli, Gennaro; Mayol, Luciano; Miccio, Lisa; Pescen, Giuseppe; Sasso, Antonio

Optical Tweezers as a Probe for Oligodeoxyribonucleotide Structuration

From Nucleosides, Nucleotides & Nucleic Acids (2007), 26(10-12), 1295-1299. DOI:10.1080/15257770701530541

23. Oliviero, Giorgia; Amato, Jussara; D'Errico, Stefano; Borbone, Nicola; Piccialli, Gennaro; Mayol, Luciano

Solid Phase Synthesis of Nucleobase and Ribose Modified Inosine Nucleoside Analogues

From Nucleosides, Nucleotides & Nucleic Acids (2007), 26(10-12), 1649-1652. DOI:10.1080/15257770701506608

22. Borbone, Nicola; Borrelli, Francesca; Montesano, Domenico; Izzo, Angelo A.; De Marino, Simona; Capasso, Raffaele; Zollo, Franco

Identification of a new sesquiterpene polyol ester from Celastrus paniculatus

From Planta Medica (2007), 73(8), 792-794. DOI:10.1055/s-2007-981543

21. De Marino, Simona; Gala, Fulvio; Borbone, Nicola; Zollo, Franco; Vitalini, Sara; Visioli, Francesco; Iorizzi, Maria

Phenolic glycosides from Foeniculum vulgare fruit and evaluation of antioxidative activity

From Phytochemistry (Elsevier) (2007), 68(13), 1805-1812. DOI:10.1016/j.phytochem.2007.03.029

20. Piccialli, Vincenzo; Borbone, Nicola; Oliviero, Giorgia

Ruthenium-catalyzed oxidative cyclization of 1,7-dienes. A novel diastereoselective synthesis of 2,7-disubstituted trans-oxepane diols

From Tetrahedron Letters (2007), 48(29), 5131-5135. DOI:10.1016/j.tetlet.2007.05.078

19. Petraccone, Luigi; Martino, Luigi; Duro, Ida; Oliviero, Giorgia; Borbone, Nicola; Piccialli, Gennaro; Giancola, Concetta

Physico-chemical analysis of G-quadruplex containing bunch-oligonucleotides

From International Journal of Biological Macromolecules (2007), 40(3), 242-247. DOI:10.1016/j.ijbiomac.2006.07.013

18. Oliviero, Giorgia; Amato, Jussara; Borbone, Nicola; D'Errico, Stefano; Piccialli, Gennaro; Mayol, Luciano

Synthesis of N-1 and ribose modified inosine analogues on solid support

From Tetrahedron Letters (2007), 48(3), 397-400. DOI:10.1016/j.tetlet.2006.11.085

17. De Marino, Simona; Borbone, Nicola; Gala, Fulvio; Zollo, Franco; Fico, Gelsomina; Pagiotti, Rita; Iorizzi, Maria

New Constituents of Sweet Capsicum annuum L. Fruits and Evaluation of Their Biological Activity

From Journal of Agricultural and Food Chemistry (2006), 54(20), 7508-7516. DOI:10.1021/jf061404z

16. Oliviero, Giorgia; Amato, Jussara; Borbone, Nicola; Galeone, Aldo; Petraccone, Luigi; Varra, Michela; Piccialli, Gennaro; Mayol, Luciano

Synthesis and Characterization of Monomolecular DNA G-Quadruplexes Formed by Tetra-End-Linked Oligonucleotides

From Bioconjugate Chemistry (2006), 17(4), 889-898. DOI:10.1021/bc060009b

15. Oliviero, Giorgia; Amato, Jussara; Borbone, Nicola; Galeone, Aldo; Varra, Michela; Piccialli, Gennaro; Mayol, Luciano

Synthesis and characterization of DNA quadruplexes containing T-tetrads formed by bunch-oligonucleotides

From Biopolymers (2006), 81(3), 194-201. DOI:10.1002/bip.20399

14. Sepe, Valentina; D'Orsi, Rosa; Borbone, Nicola; Valeria D'Auria, Maria; Bifulco, Giuseppe; Monti, Maria Chiara; Catania, Anna; Zampella, Angela

Callipeltins F-I: new antifungal peptides from the marine sponge Latrunculia sp.

From Tetrahedron (2006), 62(5), 833-840. DOI:10.1016/j.tet.2005.10.058

13. Zampella, Angela; D'Orsi, Rosa; Sepe, Valentina; De Marino, Simona; Borbone, Nicola; Valentin, Alexis; Debitus, Cecile; Zollo, Franco; D'Auria, Maria Valeria

Isolation of plakinamine I: A new steroidal alkaloid from the marine sponge Corticium sp. and synthesis of an analogue model compound

From European Journal of Organic Chemistry (2005), (20), 4359-4363. DOI:10.1002/ejoc.200500364

12. Oliviero, Giorgia; Amato, Jussara; Borbone, Nicola; Galeone, Aldo; Varra, Michela; Piccialli, Gennaro; Mayol, Luciano

Unusual monomolecular DNA quadruplex structures using bunch-oligonucleotides

From Nucleosides, Nucleotides & Nucleic Acids (2005), 24(5-7), 739-741. DOI:10.1081/NCN-200060048

11. Borbone, Nicola; D'Isa, Giuliana; Oliviero, Giorgia; Piccialli, Gennaro; Varra, Michela; Mayol, Luciano

Effects of acrolein on the quadruplex forming d(TTAGGG)4 telomeric repeat sequence

From Nucleosides, Nucleotides & Nucleic Acids (2005), 24(5-7), 447-450. DOI:10.1081/NCN-200059993

10. Borbone, Nicola; Oliviero, Giorgia; Galeone, Aldo; Piccialli, Gennaro; Varra, Michela; Mayol, Luciano

A bunch-oligonucleotide forming stable monomolecular quadruplex containing a T-tetrad

From Nucleosides, Nucleotides & Nucleic Acids (2005), 24(5-7), 443-446. DOI:10.1081/NCN-200059989

9. De Marino, Simona; Borbone, Nicola; Zollo, Franco; Ianaro, Angela; Di Meglio, Paola; Iorizzi, Maria

New sesquiterpene lactones from Laurus nobilis leaves as inhibitors of nitric oxide production

From Planta Medica (2005), 71(8), 706-710. DOI:10.1055/s-2005-864191

8. De Marino, Simona; Borbone, Nicola; Zollo, Franco; Ianaro, Angela; Di Meglio, Paola; Iorizzi, Maria

Megastigmane and Phenolic Components from Laurus nobilis L. Leaves and Their Inhibitory Effects on Nitric Oxide Production

From Journal of Agricultural and Food Chemistry (2004), 52(25), 7525-7531. DOI:10.1021/jf048782t

7. Borrelli, Francesca; Borbone, Nicola; Capasso, Raffaele; Montesano, Domenico; Izzo, Angelo A.; De Marino, Simona; Capasso, Francesco; Ferrara, Lydia; Longo, Rocco; Zollo, Franco

New sesquiterpenes with intestinal relaxant effect from Celastrus paniculatus

From Planta Medica (2004), 70(7), 652-656. DOI:10.1055/s-2004-827190

6. Oliviero, Giorgia; Borbone, Nicola; Galeone, Aldo; Varra, Michela; Piccialli, Gennaro; Mayol, Luciano

Synthesis and characterization of a bunchy oligonucleotide forming a monomolecular parallel quadruplex structure in solution

From Tetrahedron Letters (2004), 45(25), 4869-4872. DOI:10.1016/j.tetlet.2004.04.149

5. Montesano, Domenico; Sgueglia, Maria Valeria; Ferrara, Lydia; Naviglio, Daniele; Borbone, Nicola

Useful products in bergamot fruit (Citrus bergamia)

From Ingredienti Alimentari (2003), 2(6), 17-23. Language: Italian, Database: CAPLUS ISSN: 1594-0543

4. De Marino, Simona; Borbone, Nicola; Iorizzi, Maria; Esposito, Giuseppe; McClintock, James B.; Zollo, Franco

Bioactive asterosaponins from the starfish Luidia quinaria and Psilaster cassiope. Isolation and structure characterization by two-dimensional NMR spectroscopy

From Journal of Natural Products (2003), 66(4), 515-519. DOI:10.1021/np0205046

3. Zampella, Angela; Randazzo, Antonio; Borbone, Nicola; Luciani, Sisto; Trevisi, Lucia; Debitus, Cecile; D'Auria, Maria Valeria

Isolation of callipeltins A-C and of two new open-chain derivatives of callipeltin A from the marine sponge Latrunculia sp. A revision of the stereostructure of callipeltins

From Tetrahedron Letters (2002), 43(35), 6163-6166. DOI:10.1016/S0040-4039(02)01334-5

2. Borbone, Nicola; De Marino, Simona; Iorizzi, Maria; Zollo, Franco; Debitus, Cecile; Esposito, Giuseppe; Iuvone, Teresa

Minor steroidal alkaloids from the marine sponge Corticium sp.

From Journal of Natural Products (2002), 65(8), 1206-1209. DOI:10.1021/np020027r

1. Borbone, Nicola; De Marino, Simona; Iorizzi, Maria; Zollo, Franco; Debitus, Cecile; Ianaro, Angela; Pisano, Barbara

New glycosphingolipids from the marine sponge Aplysinella rhax and their potential as nitric oxide release inhibitors

From European Journal of Organic Chemistry (2001), (24), 4651-4656. DOI:10.1002/1099-0690(200112)2001:24<4651::AID-EJOC4651>3.0.CO;2-2