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Aging disrupts hepatocyte zonation homeostasis in mice and humans.
Sinha S, Ali Q, Zhang T, Nguyen DH, Hanna S, Sethiadi J, Hissong E, Schwartz RE, et al.
Hepatology, 2025.
Mesenteric parametrial fat pad surgery for in vivo implantation of hepatocytes in nude mice.
Sinha S, Nguyen DH, Hassan N, Ali Q, Sethiadi J, Tsoy S, Schwartz RE.
Bio-protocol, 2024.
A 3D biomimetic model of lymphatics reveals cell–cell junction tightening and lymphedema via a cytokine-induced ROCK2/JAM-A complex.
E Lee, SL Chan, Y Lee, WJ Polacheck, S Kwak, A Wen, DHT Nguyen, ML Kutys, S Alimperti, AM Kolarzyk, et al.
Proceedings of the National Academy of Sciences, 2023.
Adenosine deaminase 2 produced by infiltrative monocytes promotes liver fibrosis in nonalcoholic fatty liver disease.
S Tiwari-Heckler, EU Yee, Y Yalcin, J Park, DHT Nguyen, W Gao, E Csizmadia, N Afdhal, KJ Mukamal, et al.
Cell Reports, 2021.
Cell and tissue therapy for the treatment of chronic liver disease.
Y Bram, DHT Nguyen, V Gupta, J Park, C Richardson, V Chandar, RE Schwartz.
Annual Review of Biomedical Engineering, 2021.
Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate.
TM Lu, S Houghton, T Magdeldin, JGB Durán, AP Minotti, A Snead, A Sproul, DHT Nguyen, J Xiang, HA Fine, et al.
Proceedings of the National Academy of Sciences, 2021.
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids.
Y Han, X Duan, L Yang, BE Nilsson-Payant, P Wang, F Duan, X Tang, TM Yaron, T Zhang, S Uhl, Y Bram, C Richardson, J Zhu, Z Zhao, D Redmond, S Houghton, DHT Nguyen, et al.
Nature, 2021.
Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis.
B Palikuqi, DHT Nguyen, G Li, R Schreiner, AF Pellegata, Y Liu, D Redmond, F Geng, Y Lin, et al.
Nature, 2020.
A human pluripotent stem cell-based platform to study SARS-CoV-2 tropism and model virus infection in human cells and organoids.
Y Han, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DHT Nguyen, et al.
Cell Stem Cell, 2020.
Identification of candidate COVID-19 therapeutics using hPSC-derived lung organoids.
Y Han, TM Yaron, P Wang, X Tang, T Zhang, Z Zhao, Y Bram, D Redmond, S Houghton, D Nguyen, et al.
BioRxiv, 2020.
A biomimetic pancreatic cancer on-chip reveals endothelial ablation via ALK7 signaling.
DHT Nguyen, E Lee, S Alimperti, RJ Norgard, A Wong, JJK Lee, J Eyckmans, BZ Stanger, CS Chen.
Science Advances, 2019.
Human induced pluripotent stem cell-derived neuroectodermal epithelial cells mistaken for blood-brain barrier-forming endothelial cells.
TM Lu, D Redmond, T Magdeldin, DHT Nguyen, A Snead, A Sproul, J Xiang, K Shido, HA Fine, Z Rosenwaks, et al.
BioRxiv, 2019.
Cdc42 regulates branching in angiogenic sprouting in vitro.
DH Nguyen, L Gao, A Wong, CS Chen.
Microcirculation, 2017.
Fluid shear stress threshold regulates angiogenic sprouting.
PA Galie, DHT Nguyen, CK Choi, DM Cohen, PA Janmey, CS Chen.
Proceedings of the National Academy of Sciences, 2014.
Label-free evaluation of angiogenic sprouting in microengineered devices using ultrahigh-resolution optical coherence microscopy.
F Li, T Xu, DHT Nguyen, X Huang, CS Chen, C Zhou.
Journal of Biomedical Optics, 2014.
Delineating 3D angiogenic sprouting in OCT images via multiple active contours.
T Xu, F Li, DHT Nguyen, CS Chen, C Zhou, X Huang.
International Workshop on Medical Imaging and Virtual Reality, 2013.
Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro.
DHT Nguyen, SC Stapleton, MT Yang, SS Cha, CK Choi, PA Galie, CS Chen.
Proceedings of the National Academy of Sciences, 2013.
Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues.
JS Miller, KR Stevens, MT Yang, BM Baker, DHT Nguyen, DM Cohen, E Toro, AA Chen, PA Galie, X Yu, et al.
Nature Materials, 2012.