Pulications

1. Shah R. Ali1, Ngoc Uyen Nhi Nguyen1, Ching Cheng Hsu, Shujuan Li, Ivan Menendez Montes, Zhaoning Wang, Miao Cui, Abdallah Elnwasany, Feng Xiao, Jisheng Sun, Suwannee Thet, Nicholas T. Lam, Alisson Cardoso, Ana Helena Pereira, Jinhu Wang, Eric N. Olson, Michael T. Kinter, Luke I. Szweda, John Shelton, Wataru Kimura, Hesham A. Sadek. Paracrine IGFBP3 spatially coordinates IGF signaling to induce myocardial regeneration in mice. Journal of Molecular and Cellular Cardiology. Volume 207, October 2025, 93-106. 1Contributed equally.

2. Wang P*, Ahmed MS*, Nguyen NUN*, Menendez-Montes I, Hsu CC, Farag A, Thet S,  Lam NT, Wansapura J, Crossley E, Ma N, Zhao SR, Zhang TJ, Morimoto S, Singh R, Elhelaly W, Tassin TC, Cardoso AC, Williams NS, Pointer HL, Elliott DA, McNamara JW,  Watt KI, Porrello ER,  Sadayappan S,  Sadek HA. An FDA-Approved Drug Structurally and Phenotypically Corrects the K210del Mutation in Genetic Cardiomyopathy Models. J Clin Invest. 2025;135(4):e174081. *Contributed equally.

3. Lam NT, Nguyen NUN, Elhelaly W M., Hsu CC, Menendez-Montes I, Xiao F, Ali SR, Vo N, Briard N, El-Feky L, Omari QM, Cardoso AC, Liu Y, Ahmed MS, Li S, Thet S, Xing C, Zangi L, Sadek HA. Induced Cytokinesis Generates Highly Proliferative Mononuclear Cardiomyocytes at the Expense of Contractility. Circulation. 2025;151:1009–1023. 

1. Wu YJ, Chiao CC, Chuang PK, Hsieh CB, Ko CY, Ko CC, Chang CF, Chen TY, Nguyen NUN, Hsu CC, Chu TH, Fang CC, Tsai HY, Tsai HC, Anuraga G, Ta HDK, Xuan DTM, Kumar S, Dey S, Wulandari FS, Manalu RT, Ly NP, Wang CY, Lee YK. Comprehensive Analysis of Bulk and Single-cell RNA sequencing Data Reveals Schlafen-5 (SLFN5) As a Novel Prognosis and Immunity. Int J Med Sci 2024; 21(12):2348-2364. 

2. Nguyen NUN*†, Hsu CC*, Ali SR, Wang HV†. Actin-organizing Protein Palladin Modulates C2C12 Cell Fate Determination. Biochemistry and Biophysics Reports 39 (2024) 101762. *Contributed equally. †Corresponding authors.

3. Xiao F*, Nguyen NUN*, Wang P, Li S, Hsu CC, Thet S, Kimura W, Luo X, Lam NT, Menendez-Montes I, Elhelaly W, Cardoso AC, Pereira  AHM, Singh R, Sadayappan S, Kanchwala M, Xing C, Ladha FA, Hinson JT, Hajjar RJ, Hill JA, and Sadek HA. Adducin Regulates Sarcomere Disassembly During Cardiomyocyte Mitosis. Circulation 2024;150:791–805. *Contributed equally.

4. Liu CH, Ho YC, Lee WC, Huang CY, Lee YK, Hsieh CB, Huang NC, Wu CC, Nguyen NUN, Hsu CC, Chen CH, Chen YC, Huang WC, Lu YY, Fang CC, Chang YC, Chang CL, Tsai MK, Wen ZH, Li CZ, Li CC, Chuang PK, Yang SM, Chu TH, Huang SC. Sodium-Glucose Co-Transporter-2 Inhibitor Empagliflozin Attenuates Sorafenib-Induced Myocardial Inflammation and Toxicity. Environmental Toxicology 2024; 0:1–15.

5. Ahmed MS*, Nguyen NUN*, Nakada Y, Hsu CC, Farag A, Lam NT, Wang P, Thet S, Menendez-Montes I, Elhelaly WM, Lou X, Secco I, Tomczyk M, Zentilin L, Pei J, Cui M, Dos Santos M, Liu X, Liu Y, Zaha D, Walcott G, Tomchick D, Xing C, Zhang CC, Grishin NV, Giacca M, Zhang Y, Sadek HA. Identification of FDA-Approved Drugs That Induce Heart Regeneration in Mammals. Nat. Cardiovasc. Res. 3, 372–388 (2024). *Contributed equally. (accompanied by an Editorial: Yuan, X., Braun, T. Toward drug-induced heart regeneration.)  

6. Ali SR*, Nguyen NUN*, Menendez-Montes I, Hsu CC, Elhelaly W, Lam NT, Li S, Elnwasany A, Nakada Y, Thet S, Foo RSY, Sadek HA. Hypoxia-induced stabilization of HIF2A promotes cardiomyocyte proliferation by attenuating DNA damage. J Cardiovasc Aging 2024;4:11. *Contributed equally.

1. Ahmed MS*, Farag AB*, Boys IN*, Wang P*, Menendez-Montes I, Nguyen NUN, Eitson JL, Ohlson MB, Fan WC, McDougal MB, Mar K, Thet S, Ortiz F, Kim SY, Solmonson A, Williams NS, Lemoff A, DeBerardinis RJ, Schoggins JW, Sadek HA. FDA approved drugs with antiviral activity against SARS-CoV-2: From structure-based repurposing to host-specific mechanisms. Biomedicine & Pharmacotherapy 162 (2023) 11461. *Contributed equally.

2. Shih PC*, Chen HP*, Hsu CC, Lin CH, Ko CY, Hsueh CW, Huang CY, Chu TH, Wu CC, Ho YC, Nguyen NUN, Huang SC, Fang CC, Tzou SJ, Wu YJ, Chen TY, Chang CF, and Lee YK. Long-term DEHP/MEHP exposure promotes colorectal cancer stemness associated with glycosylation alterations. Environmental Pollution 327 (2023) 121476.

1. Lam NT*, Nguyen NUN*, Ahmed MS, Hsu CC, Coronado PER, Li S, Menendez-Montes I, Thet S, Elhelaly WM, Xiao F, Wang X, Williams NS, Canseco DC, Red-Horse K, Rothermel BA, Sadek HA. Targeting calcineurin induces cardiomyocyte proliferation in adult mice. Nat Cardiovasc Res 1, 679–688 (2022). *Contributed equally. (accompanied by an Editorial: Watanabe, H., Sucov, H.M. Cardiomyocyte proliferation by calcineurin inhibition.)

1. Ahmed MS*, Wang P*, Nguyen NUN, Nakada Y, Menendez-Montes I, Ismail M, Bachoo R, Henkemeyer M, Sadek HA, and Kandil ES. Identification of tetracycline combinations as EphB1 tyrosine kinase inhibitors for treatment of neuropathic pain. PNAS 2021 Vol. 118 No. 10 e2016265118. *Contributed equally.

1. Nguyen NUN, Canseco DC, Xiao F, Nakada Y, Li S, Lam NT, Muralidhar SA, Savla J, Hill JA, Le V, Zidan K, El-Feky HW, Wang Z, Ahmed MS, Hubbi ME, Menendez-Montes I, Moon J, Ali SR, Le V, Villalobos E, Mohamed MS, Elhelaly WM, Thet S, Anene-Nzelu CG, Tan WLW, Foo RS, Meng X, Kanchwala M, Xing C, Roy J, Cyert MS, Rothermel BA, Sadek HA. A Calcineurin-Hoxb13 Axis Regulates The Growth Mode of Mammalian Cardiomyocytes. Nature 582, 271–276 (2020).

2. Li S, Nguyen NUN, Xiao F, Menendez-Montes I, Nakada Y, Tan WLW, Anene-Nzelu CG, Foo R, Thet S, Cardoso AC, Wang P, Elhelaly WM, Lam NT, Pereira, Hill JA, Sadek HA. Mechanism of Eccentric Cardiomyocyte Hypertrophy in Response to Severe Mitral Regurgitation. Circulation 2020; 141:1787–1799. 

3. Cardoso AC*, Lam NT*, Savla JJ*, Nakada Y, Pereira AHM, Elnwasany A, Menendez-Montes I, Ensley EL, Bezan Petric UB, Sharma G, Sherry AD, Malloy CR, Khemtong C, Kinter M, Tan WLW, Anene-Nzelu CG, Foo RSL, Nguyen NUN, Li S, Ahmed MS, Elhelaly WM, Abdisalaam S, Asaithamby A, Xing C, Kanchwala M, Vale G, Eckert KM, Mitsche MA, McDonald JG, Hill JA, Huang L, Shaul PW, Szweda LI, and Sadek HA. Mitochondrial substrate utilization regulates cardiomyocyte cell-cycle progression. Nat Metab 2, 167–178 (2020). *Contributed equally.

1. Villalobos E, Criollo A, Schiattarella GG, Altamirano F, French KM, May HI, Jiang N, Nguyen NUN, Romero D, Roa JC, García L, Diaz-Araya G, Morselli E, Ferdous A, Conway SJ, Sadek HA, Gillette TG, Lavandero S, Hill JA. Fibroblast Primary Cilia are Required for Cardiac Fibrosis. Circulation2019;139:2342–2357.

2. Nakada Y, Nguyen NUN, Xiao F, Savla J, Lam NT, Abdisalaam S, Bhattacharya S, Mukherjee S, Asaithamby A, Gillette TG, Hill JA, and Sadek HA. DNA Damage Response Mediates Pressure Overload-Induced Cardiomyocyte Hypertrophy. Circulation 2019; 139:1237–1239.

1. Rotter D, Peirisb H, Grinsfelder DB, Martin AM, Burchfield J, Parra V, Hull C, Morales CR, Jessup CF, Matusica D, Parks BW, Lusis AJ, Nguyen NUN, Oh M, Iyoke I, Jakkampudi T, McMillan DR, Sadek HA, Watt MJ, Gupta RK, Pritchard MA, Keating DJ & Rothermel BA. Regulator of Calcineurin 1 helps coordinate whole-body metabolism and thermogenesis. EMBO Reports (2018) 19: e44706.

1. Nguyen NUN, Wang HV. Dual Roles of Palladin Protein in In Vitro Myogenesis: Inhibition of Early Induction but Promotion of Myotube Maturation. PLOS ONE (2015) 10(4): e0124762.

1. Nguyen NUN, Liang VR, Wang HV. Actin-associated protein palladin is required for migration behavior and differentiation potential of C2C12 myoblast cells. Biochemical and Biophysical Research Communications 452 (2014) 728–733

Islam M, Nguyen NUN, Diwan A, and Rothermel BA. Chapter 8: Autophagy in germ cells, stem cells, and iPSCs, in Autophagy in Health and Disease, 2nd Edition. 2021. ISBN: 9780128220030