NeuroArt

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Are you working with in vivo optogenetics? Ever wondered what the impact of shining laser light within the brain in the absence of exogenous opsins has on neuronal activity? 👉 New preprint out: https://www.biorxiv.org/content/10.1101/2024.08.14.607152v1

Are you at #FENS2024?

Please drop by my poster PS06-28PM-506:

"Cortical layer 6 mediates intra- and inter-hemispheric connectivity and its hierarchal organisation"

Friday 28 June 14:00 – 17:30 (Poster Session 06)

wt @TeichertManuel & Troy Margrie

New preprint out:
https://www.biorxiv.org/content/10.1101/2024.05.01.590702v2

New Paper out:

https://www.nature.com/articles/s41467-024-47459-2

Let's chat at SfN 2023 in Washington DC
Interested in interhemispheric communication?
Interested in cortical Layer 6?
If so, please come to my poster at @SfNtweets #SfN23, work together with Troy Margrie @SWC_NeuroMonday 13.11, 8-12 (GMT-5), PSTR212.01, Board no. DD2, WCC Halls A-C
We show that L6 cells globally provide strong callosal projections. In mouse primary visual cortex, we find that these L6 cells influence both local cortical and subsequent thalamic processing via its integration with L6 microcircuits.

New preprint, first postdoc paper!

A primary sensory cortical interareal feedforward inhibitory circuit for tacto-visual integrationTactile sensation and vision are often both utilized for the exploration of objects that are within reach though it is not known whether or how these two distinct sensory systems might combine such information. Here in mice we find that stimulation of the contralateral whisker array suppresses visually evoked activity in a subarea of primary visual cortex (VISp) whose visual space covers the whisker search space. This is mediated by local fast spiking interneurons that receive a direct cortico-cortical input predominantly from layer 6 of the primary somatosensory barrel cortex (SSp-bfd). These data demonstrate functional convergence within and between two primary sensory cortical areas for multisensory object detection and recognition. ### Competing Interest Statement The authors have declared no competing interest.

New paper out!

Functional and structural features of L2/3 pyramidal cells continuously covary with pial depth in mouse visual cortexAbstract. Pyramidal cells of neocortical layer 2/3 (L2/3 PyrCs) integrate signals from numerous brain areas and project throughout the neocortex. These PyrCs sh

Asymmetry as a building block of neuronal computationsOne of the most exciting questions in neuroscience is how the function of a neuron is related to its structure and spatial connectivity. Researchers at the Max Planck Institute for Biological Intelligence, in foundation (i.f.) have now gained new insights into this: Neurons in mouse visual cortex respond to a certain orientation and movement of an object. Now it turns out that both the structure of a neuron and the arrangement of its connection partners reflect this behavior. In particular, asymmetric structures seem to have a decisive influence on object perception.

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