The Nepo represents the elaborate mathematical system which was created and developed by the first people of the American continents. One must learn a bit about its culture and language in order to understand the Nepo. This system was started by Olmec ancestors who designed an instrument to count and calculate similar to a "manual computer", with which you could add, subtract, multiply, divide, and perform higher calculations. Later, the Mayans perfected it and the knowledge passed to the Mexica (Aztecs), who used it to facilitate commercial exchange and for many other uses. Tenochtitlán/Tlateloco (Mexico City) has always had at its heart one of the largest mercados in the world, one which continues today as the
Central de Abastos. Of course they would have had an advanced system to support that level of commerce and to calculate with great accuracy their astronomical observations.