Publications & Patents

37. Wooil Choi, Dong Jun Park, Robert A. Dorschner, Katie Pool, Sakeef Sayeed, Jenny Kezios, Jaebin Lee, Sebastian Adlawan, and Brian P. Eliceiri. (2025) Regulated release of small extracellular vesicles directs neutrophil recruitment in cutaneous wound healing Journal of Investigative Dermatology. (PMID: 40914410)

36. Keita Nakatsutsumi, Dong Jun Park, Wooil Choi, William Johnston, Katie Pool, Raul Coimbra, Brian Eliceiri, Todd W Costantini. (2025) Lung Contusion Worsens Lung Injury via Altering micro-RNA Content in Alveolar Small Extracellular Vesicles. J. Trauma Acute Care Surg. (PMID: 40413349)

35. Wooil Choi, Dong Jun Park, Robert A. Dorschner, Keita Nakatsutsumi, Michelle Yi, Hanan Zhang, and Brian P. Eliceiri. (2025) CDK1-loaded extracellular vesicles promote histone phosphorylation and wound healing in diabetic obese mice. Molecular Therapy (PMID: 39865653)

34. Keita Nakatsutsumi, Wooil Choi, William Johnston, Katie Pool, Dong Jun Park, Jessica L Weaver, Raul Coimbra, Brian Eliceiri, Todd W Costantini. (2025) Lung contusion complicated by pneumonia worsens lung injury via the inflammatory effect of alveolar small extracellular vesicles on macrophages and epithelial cells. J. Trauma Acute Care Surg. (PMID: 39621452)

33. Dong Jun Park, Wooil Choi, Hanan Zhang, Brian Eliceiri. (2024) Lineage mapping of extracellular vesicles: What cells do they come from and where do they go? Advanced in Wound Care. (PMID: 39099339)

32. Wooil Choi, Dong Jun Park, Brian P. Eliceiri. (2024) Defining tropism and activity of natural and engineered extracellular vesicles. Frontiers in Immunology.
(PMID: 38660297)

31. Dong Jun Park, Wooil Choi, Sakeef Sayeed, Kayla Ho, Jenny Kezios, Robert Dorschner, John Nolan, Brian P. Eliceiri. (2024) Defining the activity of pro-reparative extracellular vesicles in wound healing based on miRNA payloads and cell type-specific lineage mapping. Molecular Therapy. (PMID: 38379282)

30. Joshua A. Welsh, Deborah C.I. Coberdhan, …Dong Jun Park, Clotilde Thery, and Kenneth W. Witwer. (2024) Minimal information for studies of extracellular vesicles (MISEV2023): from basic to advanced approaches. Journal of Extracellular Vesicles. (PMID: 38326288)

29. Jin Sil Choi, Ye Ji Ahn, Su Hoon Lee, Dong Jun Park, Jeong Eun Park, Wan Su Yun, Sun Mok Ha, Young Joon Seo. (2023) Role of Kir4.1 channels in aminoglycoside induced ototoxicity of hair cells. BioMed Research International. (PMID: 38143588)

28. Todd W. Costantini, Dong Jun Park, William Johnston, Keita Nakatsutsumi, Kezios Jenny, Jessica L. Weaver, Raul Coimbra, Brian P. Eliceiri1. (2023) A Heterogenous Population of Extracellular Vesicles Mobilize to Lung Post-Injury. The Journal of Trauma and Acute Care Surgery. 96(3):371-377 (PMID: 37880828)

27. Jeong-Eun Park, Woo Cheol Kim, Sung Kyun Kim, Yeji Ahn, Sun Mok Ha, Gahee Kim, Seonmin Choi, Wan Su Yun, Tae Hoon Kong, Su Hoon Lee, Dong Jun Park, Jin Sil Choi, Jaehong Key, and Young Joon Seo. (2022) Protection of hearing loss in ototoxic mouse model through SPIONs and dexamethasone-loaded PLGA nanoparticle delivery by magnetic attraction. International Journal of Nanomedicine. 17:6317-6334. (PMID: 36536939)

26. Dong Jun Park, Gyeongchan Jeon, Hyojin Choi, Ngoc-Tu Nguyen, Yang Hoon Kim, and Jiho Min. (2022) Melanin treatment effect of vacuoles‑Zinc Oxide nanoparticles combined with ascorbic acid. Molecular Biotechnology. 1-10. (PMID: 36445610) (Co-first author)

25. Dong Jun Park, Erika Duggan, Robert Dorschner, Marek Dobke, John Nolan, Brian P. Eliceiri. (2022) Serpin-loaded extracellular vesicles promote tissue repair in a mouse model of impaired wound healing. Journal of Nanobiotechnology. 20:474 (PMID: 36335351)

24. Dong Jun Park, Jeong-Eun Park, Su Hoon Lee, Brian P. Eliceiri, Jin Sil Choi, Sung Kyun Kim, Young Joon Seo. (2021) Protective effect of cisplatin-induced apoptosis by heat shock protein 70 of mesenchymal stem cell-derived exosome in auditory explant model. International Journal of Nanomedicine. 17:6317-6334. (PMID: 36536939)

23. Dong Jun Park. (2021) Standardized Methodologies to Utilize Exosome Treatment as Potential Nano Substances in Hearing Loss. Journal of Otorhinol. Hear & Balance Med. 2(2), 6. (LINK)

22. Dong Jun Park, Ngoc-Tu Nguyen, Bit-Na Kim, Yang-Hoon Kim, Jiho Min. (2021) Intracellular protein delivery using QRPL-a vacuolar targeting signal on carboxypeptidase Y. Enzyme and Microbial Technology. 149(1), 109848. (PMID: 34311885)

21. Dong Jun Park, Young Joon Seo. (2021) Engineering of Extracellular Vesicles Based on Payload Changes for Tissue Regeneration. Tissue Engineering and Regenerative Medicine. 18: 485–497. (PMID: 34050888)

20. Dong Jun Park, Jeong-Eun Park, Tae Hoon Kong, Young Joon Seo. (2021) Alteration of Payload in Extracellular Vesicles by Crosstalk with Mesenchymal Stem Cells from Different Origin. Journal of Nanobiotechnology. 19(1):148. (PMID:34016123)

19. Cheol Woo Park, Dong Jun Park. (2021) Development of Er3+, Yb3+ Co-Doped Y2O3 NPs according to Yb3+ Concentration by LP-PLA Method: Potential Further Biosensor. Biosensors. 11, 150. (PMID: 34065000)

18. Su Hoon, Sun Mok Ha, Min Jae Jeong, Dong Jun Park, Carlos Noriega Polo, Young Joon Seo, Seong Heon Kim. (2021) Effects of Wonju City particulate matter-induced ROS generation on mitochondrial dysfunction in human middle ear epithelial cells. Environ. Sci. Poll. Res. 1-14. (PMID: 33932209)

17. Jin Qian, Dong Jun Park, Sophia Perrott, Parth Patel, and Brian P. Eliceiri. (2021) Genetic background and kinetics define wound bed extracellular vesicles in a mouse model of cutaneous injury. International Journal of Molecular Science. 22(7):3551. (PMID:33805585)

16. Ye Ji Ahn, Wan Su Yun, Jin Sil Choi, Woo Cheol Kim, Su Hoon Lee, Dong Jun Park, Jeong Eun Park, Jaehong Key, Young Joon Seo. (2021) Biodistribution of poly clustered superparamagnetic iron oxide nanoparticle labeled mesenchymal stem cells in aminoglycoside induced ototoxic mouse model. Biomed. Eng. Lett. 11(1):39-53. (PMID:33747602)

15. Dong Jun Park, Wan Su Yun, Woo Cheol Kim, Jeong-Eun Park, Su Hoon Lee, Sunmok Ha, Jin Sil Choi, Jaehong Key, and Young Joon Seo. (2020) Improvement of stem cell-derived exosome release efficiency by surface modified nanoparticles. Journal of Nanobiotechnology. 18(1):178. (PMID:33287848)

14. Jeong-Eun Park, Su Hoon Lee, Dong Jun Park, Young Joon Seo, Sung Kyun Kim. (2020) In Vitro Time-lapse Live Cell Imaging to Explore Cell Migration Toward the Organ of Corti. JoVE. E61947. (PMID: 33346204)

13. Dong Jun Park, Sunmok Ha, Jin Sil Choi, Su Hoon Lee, Jeong-Eun Park, and Young Joon Seo. (2020) Induced Short-Term Hearing Loss due to Stimulation of Age-Related Factors by Intermittent Hypoxia, High-Fat Diet, and Galactose Injection. International Journal of Molecular Sciences. 21(19): 7068-7085. (PMID:32992845)

12. Dong Jun Park, Su Hoon Lee, Wan Su Yun, Jeong-Eun Park, Jin Sil Choi, Jaehong Key, and Young Joon Seo. (2020) Endocytic trafficking of polymeric clustered superparamagnetic iron oxide nanoparticles in mesenchymal stem cells. Journal of Controlled Release. 326: 408-418. (PMID: 32711014)

11. Sunmok Ha, Kyu Rin Hwang, Il Hwan Park, Sunyoung Park, Jin Sil Choi, Dong Jun Park, Jeong-Eun Park, Su Hoon Lee, Hye Young Lee, and Young Joon Seo, MD. (2020) Circulating microRNAs as potentially new diagnostic biomarkers of idiopathic sudden sensorineural hearing loss. Acta Oto-Laryngologica. 1:1-8.
(PMID: 32876518)

10. Dong Jun Park, Wooil Choi, Seung Heuck Bang, Sang Yong Kim, Ji-Hyang Wee, Yang-Hoon Kim and Jiho Min. (2020) Vacuolar Targeting of Aldehyde Dehydrogenase 6 Tagging with Signal Peptide of Proteinase A. Journal of Basic Microbiology. 60(4): 341-350. (PMID: 32043631)

9. Dong Jun Park, Gyeongchan Jeon, Seung Hyuck Bang, Sang Yong Kim, Yang-Hoon Kim and Jiho Min. (2020) Cellular Lysosomes’ activity for melanin reduction on artificial skin tissue. Molecular Biotechnology. 62(3):185-191. (PMID:31894512)

8. Dong Jun Park, Seyoung Lee, Jihee Yoon, Seung Hyuck Bang, Yang-Hoon Kim and Jiho Min. (2018) Formaldehyde treatment using overexpressed aldehyde dehydrogenase 6 from recombinant Saccharomyces cerevisiae. Journal of Nanoscience and Nanotechnology. 18:2979-2985. (PMID: 29442983)

7. Dong Jun Park, Yang-Hoon Kim and Jiho Min. (2017) The remarkable efficiency of melanin reduction by using functional organelle, lysosomes. Journal of Nanoscience and Nanotechnology. 17(7):4638-4642.

6. Dong Jun Park, Simranjeet Singh Sekhon, Ji-Young Ahn, Hobaek Yoon, Yang-Hoon Kim and Jiho Min. (2016) Proteomic analysis of lysosomal proteins in Melanocyte B16F10 exposed to Melanin. Toxicology and Environmental Health Sciences. 8: 7-11.

5. Seung Hyuck Bang, Dong Jun Park, Yang-Hoon Kim and Jiho Min. (2016) Lysosomal membrane proteins exposed to melanin in melanocyte B16F10. Toxicology and Environmental Health Sciences. 8(3):253-257.

4. Seung Hyuck Bang, Dong Jun Park, Yang-Hoon Kim and Jiho Min. (2016) Analysis of lysosomal membrane proteins exposed to melanin in HeLa cells. Environmental Health and Toxicology. 31, e2016009. (PMID:27158002)

3. Dong Jun Park, Simranjeet Singh Sekhon, Jihee Yoon, Yang Hoon Kim, Jiho Min. (2016) Color reduction of melanin by lysosomal and peroxisomal enzymes isolated from mammalian cells. Molecular & Cellular Biochemistry. 413:119-125. (PMID: 26738491)

2. Dong Jun Park, Simranjeet Singh Sekhon, Ji-Young Ahn, Hobaek Yoon, Lyon Lee, Jung Ho Ko, Yang-Hoon Kim & Jiho Min. (2015) Different expression patterns of lysosomal proteins exposed to melanin in HeLa cells. Toxicology and Environmental Health Science. 7(5), 272-276.

1. Ju-Yong Park, Dong Jun Park, Bong-Woo Chung and Jiho Min. (2013) Expression of bacterial xylose isomerase in Saccharomyces cerevisiae under galactose supplemented condition. Biotechnology and Bioprocess Engineering. 18:528-532.

15. Dong Jun Park, Brian Eliceiri. (2025) Compositions and methods for wound healing. Registered for U.S. patent. (#US20250049898A1)

14. Dong Jun Park, J. E. Park, Y. J. Seo. (2023) Composition for preventing hearing loss containing mesenchymal stem cells or exosomes derived therefrom as active ingredient. Registered for U.S. patent. (#US20230310505)

13. Dong Jun Park, Young Joon Seo. (2023) Age-related hearing loss animal model and construction method therefor. Registered for U.S. patent. (#US20230309520)

12. Dong Jun Park, Jeong Eun Park, Young Joon Seo. (2022) Composition for preventing hearing loss containing mesenchymal stem cells or exosomes derived therefrom as active ingredient. Registered for PCT patent. (#WO2022025430)

11. Dong Jun Park, Brian Eliceiri. (2022) Wound healing treatment. Registered for PCT patent. (#WO2023122120)

10. Dong Jun Park, Young Joon Seo. (2021) Method for manufacturing Age-related deafness animal model. Registered for Korea patent. (#10-2563048), July 31st

9. Dong Jun Park, Young Joon Seo. (2021) Manufactured chamber for the animal models of senile hearing loss. Submitted for Korea patent. (#10-0094819), July 29th

8. Dong Jun Park, Jeong Eun Park, Young Joon Seo. (2020) Composition for preventing hearing loss comprising mesenchymal stem cell. Registered for Korea patent. (#10-2437638), Nov 11th

7. Dong Jun Park, Jeong Eun Park, Young Joon Seo. (2020) Composition for preventing hearing loss comprising exosome derived from mesenchymal stem cell. Registered for Korea patent. (#10-2441661), Sep 5th

6. Dong Jun Park, Jaehong Key, Young Joon Seo. (2019) Method for promoting production of stem cell-derived exosome using magnetic nanoparticle cluster. Registered for Korea patent. (#10-2236399), Mar 30th

5. Dong Jun Park, Jihee Yoon, Seyoung Lee, Jiho Min, Yang-Hoon Kim. (2019) Development of transfer vector for targeting vacuole by signal peptide sequence. Registered for Korea patent. (#10-1953950), Feb 25th

4. Dong Jun Park, Hyun Jung Park, Jiho Min. (2018) Method for quantitating lysosome in eukaryotes by cholesterol.
Registered for Korea patent. (#10-1895041), Aug 29th

3. Dong Jun Park, Ra-Mi Park, Jihee Yoon, Seung Hyuk Bang, Mi Young Heo, Jiho Min, Yang-Hoon Kim. (2015) Method of isolating lysosome from eukaryotic microorganism. Registered for Korea patent. (#10-1672783), Oct. 31th.

2. Dong Jun Park, Jihee Yoon, Jiho Min, Yang-Hoon Kim, Suk Jung Oh, and Kwang Yoon Kim. (2015) A whitening composition comprising lysosome.
Submitted for Korea patent. (#10-0116953), Aug. 19th

1. Tu Nguyen Ngoc, Dong Jun Park, Yang-Hoon Kim, and Jiho Min. (2014) A method of detecting environmental toxicity using a recombinant yeast.
Registered for Korean patent. (#10-1569442), Nov. 10th