Our research program involves development of novel synthetic strategies for small and medium-size heterocyclic organic structures relevant to medicinal research via domino/cascade/tandem pathways under metal or /metal free conditions.
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Research Areas
Research Areas
Lewis/π-Acid Catalysis for the synthesis of novel N-heterocycles
Exploration of Alkyne chemistry for novel reaction development
Green synthetic approaches for biologically relevant Heterocycles
Alkyne Chemistry
Alkyne Chemistry
Our research group’s primary focus will be to find a novel organic transformation, total synthesis of natural product, and synthesis of small drug like molecule starting from alkynes.
Medicinal Chemistry
Medicinal Chemistry
Tuberculosis (TB), one of the world’s major causes of illness and death, is an infectious disease caused by Mycobacterium tuberculosis (MTB). According to World Health Organisation estimation (WHO), approximately death of 1.4 million people was reported worldwide in 2015. The spread of multidrug-resistant (MDR) TB and the emergence of extensively drug-resistant (XDR) TB have been accelerated drug discovery effort in search of novel drug. Although Bedaquiline and Delamanid were approved for the treatment of MDR-TD over a huge gap of over 40 years, both of them have pronounced issues of toxicity. Therefore, there is an urgent need to develop new anti-TB drugs to stop the spread of the disease. Hence, the role of our research group would be to improve the synthetic efficiency of APIs of existing drugs and synthesis of active APIs for tuberculosis treatment.
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