Illustration by Alex Cagan
I am a postdoctoral researcher for the Centre for Cancer Evolution, at the Barts Cancer Institute at Queen Mary University of London. My research concerns the mathematical study of genetic heterogeneity in human tissues, with the wider goal of better understanding and quantifying cell behaviours in complex tissue architectures, and ultimately improving our understanding of oncogenesis and early tumour development. To this end I investigate mathematical properties of somatic evolution in the context of both cancerous and healthy tissue. I use methods from population genetics, dynamical systems, stochastic processes, and numerical analysis, with a focus on the construction and solution of SDE and SPDE systems. Because the immeasurable complexity of biology deprives us from understanding everything all at once, I believe the most meaningful models come from
THE ARTFUL USE OF RANDOMNESS
Mon Père N. V., Terenzi, F., & Werner, B. (2026); The Evolution of Polyclonal Competition in Aging Hematopoiesis. Cancer Discovery, 16 (9): 1765–1779. https://doi.org/10.1158/2159-8290.CD-25-0990
Marzban, S., Stiehl, T., Xie, Z., Andersen, M., Snyder, J., Gudmand-Høyer, J., Ottesen, J., Mon Père, N., ... & West, J. (2026). Modeling the evolutionary dynamics of clonal hematopoiesis. Nature Genetics, 1-11. doi.org/10.1038/s41588-026-02504-2
Mon Père, N. V., de Buyl, P., & de Buyl, S. (2022). Brownian motion in a growing population of ballistic particles. Physical Review E, 105(3), 034133. https://10.1103/PhysRevE.105.034133