Research Topic
Research Topic
Research Summary
Our research focuses on overcoming the limitations of current medical devices and treatment tools through the innovative synthesis of nanomaterials. Our work can be categorized into three main areas: (1) Implantable soft bioelectronics, (2) Nanozymes for treating ROS-related diseases, and (3) Minimally invasive devices for diagnosis and therapy.
1. Soft Bioelectronics for Implantable Devices
Current implantable medical devices face several challenges, such as the mechanical mismatch between rigid implants and soft human tissue, which can lead to complications. To address these issues, soft, stretchable conductors have been developed to integrate seamlessly with soft tissues. Our research focuses on creating innovative inorganic nanomaterials that are highly conductive and biocompatible, which are essential for effective device performance within the human body. Through these advancements, we aim to enhance the functionality of soft bioelectronics.
2. Nanozymes for ROS-Related Disease Treatment
Reactive oxygen species (ROS) play a significant role in a variety of diseases, including sepsis, Parkinson's disease, Alzheimer’s disease, and damage from ionizing radiation. Reducing ROS levels is critical to minimizing tissue damage and disease progression. Current clinical tools for ROS reduction are limited by efficacy, short half-life, and unwanted side effects. Inorganic nanozymes, which mimic natural enzymes, offer a promising solution by catalytically scavenging ROS. Our research aims to enhance these catalytic activities to maximize ROS elimination, providing a more effective approach to treating ROS-related diseases.
3. Minimally Invasive Devices for Diagnosis and Treatment
Early-stage disease detection is as crucial as treatment, as accurate diagnosis enables appropriate medical intervention and further improves patient outcomes. However, developing minimally invasive tools that reduce patient discomfort is equally important, as increased accessibility can improve diagnosis rates. Our goal is to create minimally invasive tools that can simultaneously diagnose and treat diseases, offering effective, patient-friendly solutions for both diagnosis and therapy.