Publications

Localized in vivo prodrug activation using radionuclides

Jeremy M Quintana*, Fangchao Jiang*, Mikyung Kang, Victor Valladolid Onecha, Arda Könik, Lei Qin, Victoria E Rodriguez, Huiyu Hu, Nicholas Borges, Ishaan Khurana, Leou I Banla, Mariane Le Fur, Peter Caravan, Jan Schuemann, Alejandro Bertolet, Ralph Weissleder, Miles A Miller, Thomas S.C. Ng

Journal of Nuclear Medicine 66, 91-97 [link]

Spatiotemporal control of neutrophil fate to tune inflammation and repair for myocardial infarction therapy
Cheesue Kim*, Hyeok Kim*, Woo-Sup Sim*, Mungyo Jung, Jihye Hong, Sangjun Moon, Jae-Hyun Park, Jin-Ju Kim, Mikyung Kang, Sungpil Kwon, Mi-Jeong Kim, Kiwon Ban, Hun-Jun Park, Byung‐Soo Kim

Nature Communications 15, 8481 [link]

Engineered Nanoparticles for Enhanced Antitumoral Synergy Between Macrophages and T Cells in the Tumor Microenvironment
Sangjun Moon*, Mungyo Jung*, Seokhyeong Go, Jihye Hong, Hee Su Sohn, Cheesue Kim, Mikyung Kang, Byung Joon Lee, Jungwoo Kim, Jinwoong Lim, Byung‐Soo Kim

Advanced Materials 2410340 [link]

Extended Pharmacokinetics Improve Site-Specific Prodrug Activation Using Radiation
Jeremy M. Quintana, Mikyung Kang, Huiyu Hu, Thomas SC. Ng, Gregory R. Wojtkiewicz, Ella Scott, Sareh Parangi, Jan Schuemann, Ralph Weissleder, Miles A. Miller

ACS Central Science 10 (7), 1371–1382, 1 [link]

Sustained and Localized Drug Depot Release Using Radiation-Activated Scintillating Nanoparticles
Mikyung Kang, Jeremy M. Quintana, Huiyu Hu, Verônica C. Teixeira, Sven Olberg, Leou Ismael Banla, Victoria Rodriguez, William L. Hwang, Jan Schuemann, Sareh Parangi, Ralph Weissleder, and Miles A. Miller 

Advanced Materials 36 (23), 2312326 [link]

Ceria-vesicle nanohybrid therapeutic for modulation of innate and adaptive immunity in a collagen-induced arthritis model
Sagang Koo*, Hee Su Sohn*, Tae Hee Kim*, Siyeon Yang, Se Youn Jang, Seongryeol Ye, Boomin Choi, Soo Hyeon Kim, Kyoung Sun Park, Hyun Mu Shin, Ok Kyu Park, Cheesue Kim, Mikyung Kang, Min Soh, Jin Yoo, Dokyoon Kim, Nohyun Lee, Byung Soo Kim, Youngmee Jung, Taeghwan Hyeon

Nature Nanotechnology 18 (12), 1502-1514 [link]

Thyroid cancers exhibit oncogene-enhanced macropinocytosis that is restrained by IGF1R and promotes albumin-drug-conjugate response 
Huiyu Hu, Thomas SC Ng, Mikyung Kang, Ella Scott, Ran Li, Jeremy M Quintana, Dylan Matvey, Venkata R Vantaku, Ralph Weissleder, Sareh Parangi, Miles A Miller 

Clinical Cancer Research 29 (17), 3457-3470 [link]

Iron Oxide Nanoparticle-Incorporated Mesenchymal Stem Cells for Alzheimer’s Disease Treatment   

Mungyo Jung*, Hyeongseop Kim*, Jung Won Hwang, Yejoo Choi, Mikyung Kang, Cheesue Kim, Jihye Hong, Na Kyung Lee, Sangjun Moon, Jong Wook Chang, Suk-joo Choi, Soo-young Oh, Hyemin Jang, Duk L Na, Byung-Soo Kim 

Nano Letters 23 (2), 476-490 [link]

A Therapeutic Nanovaccine that Generates Anti‐Amyloid Antibodies and Amyloid‐specific Regulatory T Cells for Alzheimer's Disease    

Mungyo Jung*, Songmin Lee*, Sohui Park, Jihye Hong, Cheesue Kim, Illhwan Cho, Hee Su Sohn, Kyunghwan Kim, In Wook Park, Soljee Yoon, Sungpil Kwon, Jisu Shin, Donghee Lee, Mikyung Kang, Seokhyung Go, Sangjun Moon, Yeonseok Chung, YoungSoo Kim, Byung‐Soo Kim 

Advanced Materials 35 (3), 2207719 [link]

A Senolytic-Eluting Coronary Stent for the Prevention of In-Stent Restenosis   

Cheesue Kim*, Seul-Gee Lee*, Songhyun Lim, Mungyo Jung, Sung Pil Kwon, Jihye Hong, Mikyung Kang, Hee Su Sohn, Seokhyeong Go, Sangjun Moon, Seung-Jun Lee, Jung-Sun Kim, Byung-Soo Kim

ACS Biomaterials Science & Engineering 8 (5), 1921-1929 [link]

Nanovesicle‐mediated targeted delivery of immune checkpoint blockades to potentiate therapeutic efficacy and prevent side effects    

Mungyo Jung*, Mikyung Kang*, Byung‐Seok Kim, Jihye Hong, Cheesue Kim, Choong‐Hyun Koh, Garam Choi, Yeonseok Chung, Byung‐Soo Kim 

Advanced Materials 34 (9), 2106516 [link]

Local delivery of senolytic drug inhibits intervertebral disc degeneration and restores intervertebral disc structure     

Songhyun Lim, Seong Bae An, Mungyo Jung, Hari Prasad Joshi, Hemant Kumar, Cheesue Kim, Seuk Young Song, Ju‐Ro Lee, Mikyung Kang, Inbo Han, Byung‐Soo Kim 

Advanced healthcare materials 11 (2), 2101483 [link]

Nanocomplex‐Mediated In Vivo Programming to Chimeric Antigen Receptor‐M1 Macrophages for Cancer Therapy      

Mikyung Kang*, Seong Ho Lee*, Miji Kwon, Junho Byun, Dongyoon Kim, Cheesue Kim, Sagang Koo, Sung Pil Kwon, Sangjun Moon, Mungyo Jung, Jihye Hong, Seokhyeong Go, Seuk Young Song, Jae Hyun Choi, Taeghwan Hyeon, Yu‐Kyoung Oh, Hee Ho Park, Byung‐Soo Kim 

Advanced Materials 33 (43), 2103258 [link]

The senolytic drug JQ1 removes senescent cells via ferroptosis      

Seokhyeong Go, Mikyung Kang, Sung Pil Kwon, Mungyo Jung, Ok Hee Jeon, Byung‐Soo Kim 

Tissue Engineering and Regenerative Medicine 18 (5), 841-850 [link]

Multilayered Cell Sheets of Cardiac Reprogrammed Cells for the Evaluation of Drug Cytotoxicity       

Sung Pil Kwon, Seuk Young Song, Jin Yoo, Han Young Kim, Ju-Ro Lee, Mikyung Kang, Hee Su Sohn, Seokhyoung Go, Mungyo Jung, Jihye Hong, Songhyun Lim, Cheesue Kim, Sangjun Moon, Kookheon Char, Byung-Soo Kim  

Tissue Engineering and Regenerative Medicine 18 (5), 807-818 [link]

T‐Cell‐Derived Nanovesicles for Cancer Immunotherapy        

Jihye Hong, Mikyung Kang, Mungyo Jung, Yun Young Lee, Yongbum Cho, Cheesue Kim, Seuk Young Song, Chun Gwon Park, Junsang Doh, Byung‐Soo Kim 

Advanced Materials 33 (33), 2101110 [link]

Nanoparticle‐Mediated Blocking of Excessive Inflammation for Prevention of Heart Failure Following Myocardial Infarction         

Sung Pil Kwon, Byung‐Hee Hwang, Eun‐Hye Park, Han Young Kim, Ju‐Ro Lee, Mikyung Kang, Seuk Young Song, Mungyo Jung, Hee Su Sohn, Eunmin Kim, Chan Woo Kim, Kwan Yong Lee, Gyu Chul Oh, Eunho Choo, Songhyun Lim, Yeonseok Chung, Kiyuk Chang, Byung‐Soo Kim 

Small 17 (32), 2101207 [link]

Recovery of water-soluble bioactive components from defatted sesame meal using carbon dioxide assisted hydrothermal process          

Mulugeta G Aregay, Mikyung Kang, Byung-Soo Kim, Youn-Woo Lee  Yeonseok Chung, Kiyuk Chang, Byung‐Soo Kim 

The Journal of Supercritical Fluids 168, 105069 [link]

T‐Cell‐Mimicking Nanoparticles for Cancer Immunotherapy           

Mikyung Kang, Jihye Hong, Mungyo Jung, Sung Pil Kwon, Seuk Young Song, Han Young Kim, Ju‐Ro Lee, Seokyung Kang, Jin Han, Ja‐Hyun Koo, Ju Hee Ryu, Songhyun Lim, Hee Su Sohn, Je‐Min Choi, Junsang Doh, Byung‐Soo Kim 

Advanced Materials 32 (39), 2003368 [link]

Nanovesicles derived from iron oxide nanoparticles–incorporated mesenchymal stem cells for cardiac repair           

Ju-Ro Lee*, Bong-Woo Park*, Jonghoon Kim, Yeon Woong Choo, Han Young Kim, Jeong-Kee Yoon, Hyeok Kim, Ji-Won Hwang, Mikyung Kang, Sung Pil Kwon, Seuk Young Song, In Ok Ko, Ji-Ae Park, Kiwon Ban, Taeghwan Hyeon, Hun-Jun Park, Byung-Soo Kim 

Science advances 6 (18), eaaz0952 [link]

Comprehensive study on the formation mechanism of highly bioactive compounds from Allium hookeri root using subcritical water and their antioxidant and anticancer effects

Aye Aye Myint, Mulugeta G Aregay, Mikyung Kang, Byung-Soo Kim, Youn-Woo Lee, Jaehoon Kim 

The Journal of Supercritical Fluids 157, 104709 [link]

Interleukin‐4 Gene Transfection and Spheroid Formation Potentiate Therapeutic Efficacy of Mesenchymal Stem Cells for Osteoarthritis 

Seuk Young Song, Jihye Hong, Seukhyeong Go, Songhyun Lim, Hee Su Sohn, Mikyung Kang, Gun‐Jae Jung, Jeong‐Kee Yoon, Mi Lan Kang, Gun‐il Im, Byung‐Soo Kim 

Advanced healthcare materials 9 (5), 1901612 [link]

Immunomodulatory lipocomplex functionalized with photosensitizer-embedded cancer cell membrane inhibits tumor growth and metastasis

Han Young Kim, Mikyung Kang, Yeon Woong Choo, Seok-hyeong Go, Sung Pil Kwon, Seuk Young Song, Hee Su Sohn, Jihye Hong, Byung-Soo Kim 

Nano Letters 19 (8), 5185-5193 [link]

Cardiac-mimetic cell-culture system for direct cardiac reprogramming

Seuk Young Song, Jin Yoo, Seokhyeong Go, Jihye Hong, Hee Su Sohn, Ju-Ro Lee, Mikyung Kang, Gun-Jae Jeong, Seungmi Ryu, Seung Hyun L Kim, Nathaniel S Hwang, Kookheon Char, Byung-Soo Kim 

Theranostics 9 (23), 6734 [link]

M1 macrophage-derived nanovesicles potentiate the anticancer efficacy of immune checkpoint inhibitors

Yeon Woong Choo*, Mikyung Kang*, Han Young Kim, Jin Han, Seokyung Kang, Ju-Ro Lee, Gun-Jae Jeong, Sung Pil Kwon, Seuk Young Song, Seokhyeong Go, Mungyo Jung, Jihye Hong, Byung-Soo Kim 

ACS nano 12 (9), 8977-8993 [link]

Therapeutic efficacy-potentiated and diseased organ-targeting nanovesicles derived from mesenchymal stem cells for spinal cord injury treatment

Han Young Kim, Hemant Kumar, Min-Jae Jo, Jonghoon Kim, Jeong-Kee Yoon, Ju-Ro Lee, Mikyung Kang, Yeon Woong Choo, Seuk Young Song, Sung Pil Kwon, Taeghwan Hyeon, In-Bo Han, Byung-Soo Kim 

Nano letters 18 (8), 4965-4975 [link]

An injectable decellularized matrix that improves mesenchymal stem cell engraftment for therapeutic angiogenesis                 

Gun-Jae Jeong, Seuk Young Song, Mikyung Kang, Seokhyeong Go, Hee Su Sohn, Byung-Soo Kim 

ACS Biomaterials Science & Engineering 4 (7), 2571-2581 [link]

CO2-assisted hydrothermal reactions for ginseng extract                  

Jebin Ryu, Junho Yoon, Seungmi Ryu, Seokyung Kang, Mikyung Kang, Byung-Soo Kim, Youn-Woo Lee 

The Journal of Supercritical Fluids 135, 17-24 [link]

Dual roles of graphene oxide to attenuate inflammation and elicit timely polarization of macrophage phenotypes for cardiac repair                   

Jin Han, Yong Sook Kim, Min-Young Lim, Han Young Kim, Saerom Kong, Mikyung Kang, Yeon Woong Choo, Ju Hee Jun, Seungmi Ryu, Hye-yun Jeong, Jooyeon Park, Gun-Jae Jeong, Jong-Chan Lee, Gwang Hyeon Eom, Youngkeun Ahn, Byung-Soo Kim 

Acs Nano 12 (2), 1959-1977 [link]