HMB
Adolescent HMB
Keypoints
anovulatory cycles mostly
Mild + Hb normal = reassurance + non-hormonal treatments + observation
R/O Pregnacy dx, Bleeding dx
Hormonal therapy aims to stabilise the endometrium
Definitions
Normal menstrual blood loss:
pads/tampon changes at ≥3 hour intervals
seldom overnight
< 21 pads(or tampoons) per cycle
Excessive menstrual flow:
>7 days duration or >80 mL
necessitating changing a super pad/tampon more than every 2 hours
causing symptomatic anaemia
causing lifestyle disturbance
Menstrual cycles
often irregular and anovulatory in the first few years after menarche.
The time to establish regular ovulatory cycles increases with increasing age of menarche
Anovulatory uterine bleeding
Excessive noncyclic uterine bleeding related to immaturity of the hypothalamic-pituitary-ovarian axis (in the absence of structural uterine lesions or systemic disease)
Causes
Pregnancy: miscarriage, ectopic pregnancy, gestational trophoblastic disease
Endocrine: anovulatory, thyroid dysfunction, polycystic ovarian syndrome (PCOS)
Haematological: von Willebrand Disease, platelet function disorder, thrombocytopenia, other bleeding disorder
Medication: hormonal contraception, anticoagulants
Other: trauma, infection, malignancy, structural causes (uncommon in adolescence), gastrointestinal bleeding
Step 1. Rapid assessment
Haemodynamic stability ie shock index
Hb
Step 2. History
Menstrual history
menarche
last menstrual period
frequency (cycle length) eg every 30 days
duration
flow ?
pain
flooding
large clots (>2cm in diameter)
frequency of pad/tampon changes)
Impact on daily life: missing school, sports, social activities
Sexual history and contraception
Symptoms of
Anaemia: dizziness, shortness of breath, fatigue
Bleeding disorders: epistaxis, bleeding gums, easy bruising
Past medical history including: coagulopathy, platelet function disorders, recurrent haemorrhagic cysts, chronic medical conditions
Adolescent assessment (HEADSS screen)
Step 3. Examination
Vital signs: hypotension, tachycardia
Skin: pallor, petechiae, bruising
Abdominal examination: tenderness or pelvic mass
Secondary signs of PCOS: acne, excess facial or body hair, weight gain
Vaginal examination is rarely indicated in an adolescent. It should be discussed with a senior clinician, and if needed should only be performed once
Step 4. Severity
Mild: Flow:slight q4wkly + Haemodynamic:stable + Hb:normal
Mod: Flow:moderate q1-3wkly + Haemodyn: ? + Hb: >100
Severe: Flow:heavy OR Haemody: unstable OR Hb:<100
Step 5. Investigations
FBE
Blood group and antibody screen for severe bleeding
Ferritin
Coagulation screen
TSH
Urine or blood ßhCG (with consent)
Consider pelvic ultrasound if bleeding accompanied by pain or palpable mass
If a bleeding disorder is suspected, consider Platelet function assay (PFA) 100 and von Willebrand screen. These tests should not be done during acute bleeding or with recent NSAID use
Step 6. Management options
Mild & no desire for contraception
Reassurance
Observation
NSAIDS & TXA during menses to be considered
Moderate
TXA during menses
Hormonal Rx
COCP if no contraindications (uncontrolled HTN, CVD, migraine with focal neuro signs, thrombosis risk)
POP
Severe
Resuscitation
TXA
High dose NET
Iron infusion as required or PRBC transfusion if still unstable despite fluid resus
Specialist gyn review, consider admission
Medication details : https://www.rch.org.au/clinicalguide/guideline_index/Adolescent_Gynaecology_Menorrhagia/