Masaki Mizuno, PhD, FACSM

84 articles (22 as first author; 28 as corresponding author; * Corresponding Author) 

In preparation/In review/Under revision

• Amane Hori, Teruaki Nasu, Ryuji Saito, Kimiaki Katanosaka, Kazue Mizumura, Masaki Mizuno, and Norio Hotta. The ASIC3 inhibitor APETx2 attenuates the exaggerated muscle mechanoreflex in rats with repeated cold stress. In preparation

• Lauro C. Vianna and Masaki Mizuno. Central command during exercise: integration of feedforward and feedback cardiovascular control. In preparation

• Rie Ishizawa, Scott A. Smith, Norio Hotta, and Masaki Mizuno*. Abnormal Cardiovascular Regulation by Skeletal Muscle Reflexes in Diabetes. In preparation

• Amane Hori, Ayumi Fukazawa, Norio Hotta. Toru Kawada, Han-Kyul Kim, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and  Masaki Mizuno*. TRPV4 and Piezo channel inhibition in the isolated carotid sinus comparably suppresses baroreflex function and acts synergistically at high arterial pressures in healthy male rats. In preparation

• Amane Hori, John D. Akins, Yoshiyuki Okada, Takuro Washio, Ayumi Fukazawa, Wanpen Vongpatanasin, Masaki Mizuno*, and Qi Fu*. Insulin Resistance Elevates 24-Hours Blood Pressure Variability Through Blunted Sympathetic Reactivity to Orthostatic Stress in Older Adults With Hypertension. In preparation

• Ayumi Fukazawa, Norio Hotta, Amane Hori, Han-Kyul Kim, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and  Masaki Mizuno*. Functional expression of Piezo1 channels in mechanosensitive small dorsal root ganglion neurons innervating rat skeletal muscle. In preparation

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• Rie Ishizawa, Han-Kyul Kim, Norio Hotta, Kimiaki Katanosaka, Chiaki Kihara, Juan A. Estrada, Ayumi Fukazawa, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and Masaki Mizuno*.LPS-Induced Piezo1 Sensitization Drives Abnormal BP Regulation in Diabetic Rats. Under revision

• Ayumi Fukazawa, Amane Hori, Scott A. Smith, Norio Hotta and Masaki Mizuno*. Crosstalk Between Insulin Signaling and Ion Channels in Peripheral Sensory Afferent Neurons: Implications for Autonomic Regulation. Under revision

• Amane Hori, Ryuji Saito, Kenichi Suijo, Masaki Mizuno, and Norio Hotta. Exaggerated blood pressure response to late night low- and high-intensity resistance exercise in healthy young men. Under revision

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2026 (1)

• Kenta Yamamoto, Riko Kai, Atsuya Inao, and Masaki Mizuno. Combined Effects of Diabetes Medications and Physical Activity on Glycemic Control: A Real-World Data Study. Scientific Reports Accepted for publication

2025 (11)

• Rie Ishizawa and Masaki Mizuno. Cardiovascular regulation during exercise in diabetes. (In Japanese, Invited Review) Journal of Physical Education, Health and Recreation. Vol. 75, No. 8: 617-622, 2025.

• Ayumi Fukazawa, Norio Hotta, Hoda Yeganehjoo, Amane Hori, Han-Kyul Kim, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and Masaki Mizuno*.  Blunted pressor response to peripheral sensory afferent nerve stimulation  in intracerebroventricular-streptozotocin injected rats.  Autonomic Neuroscience Basic and Clinical Vol. 260, 103315, 2025.

• Han-Kyul Kim, Ayumi Fukazawa, Scott A. Smith, Masaki Mizuno, Beverly A. Rothermel, Teppei Fujikawa, Marco Galvan, Laurent Gautron, Johanne Pastor, Isabelle Carroll, Orson Moe, and Wanpen Vongpatanasin. High dietary phosphate intake induces hypertension and sympathetic overactivation via central fibroblast growth factor receptor signaling. Circulation Vol. 52, No. 7: 450-464, 2025.

• Daisuke Hasegawa, Amane Hori, Yukiko Okamura, Kenich Suijo,  Masaki Mizuno, and Norio Hotta. Does hypertension exacerbate the age-related exaggerated pressor response to dynamic exercise during post-exercise muscle ischemia? Physiological Reports Vol. 13, No. 11: e70365, 2025.

• Ayumi Fukazawa, Amane Hori, Juan Estrada, Han-Kyul Kim, Norio Hotta, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and Masaki Mizuno*. Insulin potentiates mechanical responses in small dorsal root ganglion neurons by increasing the sensitization of TRPV4 channels. American Journal of Physiology Cell Physiology Vol. 328, No. 6: C1982–C1994, 2025.

• Han-Kyul Kim, Juan A. Estrada, Ayumi Fukazawa, Amane Hori, Gary A. Iwamoto, Scott A. Smith, Masaki Mizuno, and Wanpen Vongpatanasin. Exercise Pressor Reflex Function Is Augmented in Rats with Chronic Kidney Disease. American Journal of Physiology Regulatory, Integrative and Comparative Physiology Vol. 328, No. 4: R460-R469, 2025.

• Amane Hori, Toru Kawada, Norio Hotta, Ayumi Fukazawa, Juan A. Estrada, Han-Kyul Kim, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and Masaki Mizuno*. Blockade of brain insulin receptor signaling impairs open-loop arterial baroreflex function via attenuated neural arc in healthy male rats. FASEB Journal Vol.39, No. 5: e70421. 2025. doi: 10.1096/fj.202403097R.

• Amane Hori and Masaki Mizuno*. True or False: Arterial Stiffening in the Seated Position. American Journal of Physiology Regulatory, Integrative and Comparative Physiology Vol. 328, No. 3: R287–R288, 2025.

• Amane Hori, Daisuke Kume, Ryuji Saito, Daisuke Hasegawa, Kenichi Suijo, Masaki Mizuno, and Norio Hotta. Two-week Paramedic Hospital Training Augments Blood Pressure Response to Isometric Handgrip Exercise in Healthy Young Men. American Journal of Physiology Regulatory, Integrative and Comparative Physiology Vol. 328, No. 3: R242-R252, 2025.

• Juan A. Estrada, Amane Hori, Ayumi Fukazawa, Rie Ishizawa, Norio Hotta, Han-Kyul Kim, Scott A. Smith, Masaki Mizuno*. Abnormal cardiovascular control during exercise: role of insulin resistance in the brain. Autonomic Neuroscience Basic and Clinical, Vol. 258, 103239, 2025. doi.org/10.1016/j.autneu.2023.103239.

• Amane Hori, Xin Su, Shota Sagasaki, Ryuji Saito, Kenichi Suijo, Seiko Miyata, Daisuke Hasegawa, Masaki Mizuno, and Norio Hotta. Sleep Deprivation Elevates Resting and Exercise Blood Pressures and Augments Pressor Response at the Exercise Onset. Medicine & Science in Sports & Exercise Vol. 57, No. 5: 996-1007, 2025

2024 (1)

• Juan A. Estrada, Rie Ishizawa, Han-Kyul Kim, Ayumi Fukazawa, Amane Hori, Norio Hotta, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and Masaki Mizuno*. Intracerebroventricular insulin injection acutely normalizes the augmented exercise pressor reflex in a rat model of type 2 diabetes mellitus. Journal of Physiology Vol. 603, No. 18: 4991-5008, 2025 Accepted for publication 2024 Aug 21. doi: 10.1113/JP286715. Online ahead of print.

2023 (7)

• Amane Hori, Ayumi Fukazawa, Kimiaki Katanosaka, Masaki Mizuno, Norio Hotta. Mechanosensitive channels in the mechanical component of the exercise pressor reflex. Autonomic Neuroscience Basic and Clinical, Vol. 250, 103128, 2023. doi.org/10.1016/j.autneu.2023.103128.

• Juan A. Estrada, Norio Hotta, Han-Kyul Kim,  Rie Ishizawa, Ayumi Fukazawa, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and Masaki Mizuno*. Blockade of endogenous insulin receptor signaling in the nucleus tractus solitarius potentiates exercise pressor reflex function in healthy male rats. FASEB Journal Vol. 37, No. 9: e23141. 2023. doi: 10.1096/fj.202300879RR.

• Hideaki Kashima, Masako Yamaoka Endo, Masako Kanda, Akira Miura, Yoshiyuki Fukuba, and Masaki Mizuno*. High-glycemic index meal acutely potentiates blood pressure response to static handgrip exercise in healthy humans. Journal of Applied Physiology Vol. 135, No. 3: 609-620, 2023.

• Alec L.E. Butenas, Rie Ishizawa, Korynne S. Rollins, Masaki Mizuno, and Steven W. Copp. Sex dependent attenuating effects of capsaicin administration on the mechanoreflex in healthy rats. American Journal of Physiology Heart and Circulatory Physiology Vol. 325, No. 2: H372-H384, 2023.

• Rie Ishizawa, Juan A. Estrada, Han-Kyul Kim, Norio Hotta, Ayumi Fukazawa, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and Masaki Mizuno*.  Neural discharge of muscle afferents and pressor response to mechanical stimulation are associated with muscle deformation velocity in rats. American Journal of Physiology Regulatory, Integrative and Comparative Physiology Vol. 325, No. 1: R13-R20, 2023.

• Ayumi Fukazawa, Amane Hori, Norio Hotta, Kimiaki Katanosaka, Juan A. Estrada, Rie Ishizawa, Han-Kyul Kim, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and Masaki Mizuno*. Antagonism of TRPV4 channels partially reduces mechanotransduction in rat skeletal muscle afferents. Journal of Physiology Vol. 601, No. 8: 1407-1424, 2023. Selected as Editor's Choice

• Kanji Matsukawa, Gary A. Iwamoto, Jere H. Mitchell, Masaki Mizuno, Han-Kyul Kim, Jon W. Williamson, Scott A. Smith. Exaggerated renal sympathetic nerve and pressor responses during spontaneously-occurring motor activity in hypertensive rats.  American Journal of Physiology Regulatory, Integrative and Comparative Physiology Vol. 324, No. 4: R497-R512, 2023.

2022 (2)

• Han-Kyul Kim, Rie Ishizawa, Ayumi Fukazawa, Zhongyun Wang, Ursa Bezan Petric, Ming-Chang Hu, Scott A. Smith, Masaki Mizuno, and Wanpen Vongpatanasin. Dapagliflozin Attenuates Sympathetic and Pressor Responses to Stress in Young Prehypertensive Spontaneously Hypertensive Rats. Hypertension. Vol. 79, No. 8: 1824–1834, 2022.

• Amane Hori, Norio Hotta, Ayumi Fukazawa, Juan A. Estrada, Kimiaki Katanosaka, Kazue Mizumura, Jun Sato, Rie Ishizawa, Han Kyul Kim, Gary A Iwamoto, Wanpen Vongpatanasin, Jere H Mitchell, Scott A. Smith, and Masaki Mizuno*. Insulin potentiates the response to capsaicin in dorsal root ganglion neurons in vitro and muscle afferents ex vivo in normal healthy rodents. Journal of Physiology Vol. 600, No. 3: 531-545, 2022.

2021 (5)

• Amane Hori, Kimiaki Katanosaka, Masaki Mizuno and Norio Hotta. Mechanobiology of cardiovascular control during exercise (In Japanese, Mini-Review). Annual report of Research Institute of Life and Health Vol. 18, 42-48, 2021.

• Daisuke Hasegawa, Amane Hori, Yukiko Okamura, Reizo Baba, Kenichi Suijo, Masaki Mizuno, Jun Sugawara, Koji Kitatsuji, Hisayoshi Ogata, Kaoru Toda, Norio Hotta. Aging exaggerates blood pressure response to ischemic rhythmic handgrip exercise in humans. Physiological Reports Vol. 9, No. 22: e15125, 2021.

• Poghni A. Peri-Okonny, Alejandro Velasco, Hamza Lodhi, Zhongyun Wang, Debbie Arbique, Beverley Adams-Huet, Gary Iwamoto, Jere H. Mitchell, Masaki Mizuno, Scott Smith, Wanpen Vongpatanasin. Differential Effects of Eplerenone vs. Amlodipine on Muscle Metaboreflex Function in Hypertensive Humans. Journal of Clinical Hypertension Vol. 23, No. 9: 1706-1714, 2021.

• Masaki Mizuno*, Norio Hotta, Rie Ishizawa, Han-Kyul Kim, Gary Iwamoto, Wanpen Vongpatanasin, Jere H. Mitchell and Scott A. Smith. The Impact of Insulin Resistance on Cardiovascular Control during Exercise in Diabetes. Exercise and Sport Sciences Reviews Vol. 49, No. 3: 157-167, 2021. Journal Cover

• Rie Ishizawa, Han-Kyul Kim, Norio Hotta, Gary A. Iwamoto, Jere H. Mitchell, Scott A. Smith, Wanpen Vongpatanasin and Masaki Mizuno*. TRPV1 sensitization of skeletal muscle afferents in type 2 diabetic rats with hyperglycemia. Hypertension Vol. 77, No. 4: 1360-1371, 2021.

2020 (2)

• Norio Hotta, Amane Hori, Yukiko Okamura, Reizo Baba, Hidehiro Watanabe, Jun Sugawara, Wanpen Vongpatanasin, Jijia Wang, Han-Kyul Kim, Rie Ishizawa, Gary A. Iwamoto, Jere H. Mitchell, Scott A. Smith and Masaki Mizuno*. Insulin resistance is associated with an exaggerated blood pressure response to ischemic rhythmic handgrip exercise in nondiabetic older adults. Journal of Applied Physiology. Vol. 129, No. 1: 144-151, 2020.

• Rie Ishizawa, Han-Kyul Kim, Norio Hotta, Gary A. Iwamoto, Wanpen Vongpatanasin, Jere H. Mitchell, Scott A. Smith and Masaki Mizuno*. Overactive exercise pressor reflex function is mediated by sensitization of muscle afferent sensory neurons in streptozotocin-induced diabetic rats. Hypertension. Vol. 75, No. 4: 1072-1081, 2020.

2019(4)

• Norio Hotta, Kimiaki Katanosaka, Kazue Mizumura, Gary A. Iwamoto, Rie Ishizawa, Han-Kyul Kim, Wanpen Vongpatanasin, Jere H. Mitchell, Scott A. Smith and Masaki Mizuno*. Insulin potentiates the response to mechanical stimuli in small dorsal root ganglion neurons and thin fiber muscle afferents in vitro. Journal of Physiology. Vol. 597, No. 20: 5049-5062, 2019.

• Han-Kyul Kim, Norio Hotta, Rie Ishizawa, Gary A. Iwamoto, Wanpen Vongpatanasin, Jere H. Mitchell, Scott A. Smith and Masaki Mizuno*.  Exaggerated pressor and sympathetic responses to stimulation of the mesencephalic locomotor region and exercise pressor reflex in type II diabetic rats. American Journal of Physiology Regulatory, Integrative and Comparative Physiology Vol. 317, No. 2: R270-R279, 2019.

• Han-Kyul Kim, Masaki Mizuno and Wanpen Vongpatanasin. Phosphate, the forgotten mineral in hypertension. Current Opinion in Nephrology and Hypertension.  Vol. 28, Issue. 4: 345-351, 2019.   

• Nan Liang, Gary A. Iwamoto, Ryan M. Downey, Jere H. Mitchell, Scott A. Smith and Masaki Mizuno*. The pressor response to concurrent stimulation of the mesencephalic locomotor region and peripheral sensory afferents is attenuated in normotensive but not hypertensive rats. Frontiers in Physiology. Vol.10, No.95: 1-11, 2019.

2018(1) 

• Rie Ishizawa and Masaki Mizuno*. The risk of hypertension and blood pressure response during exercise (In Japanese, Invited Review). Journal of Physical Education, Health and Recreation. Vol. 68, No. 9: 665-670, 2018.

2017(1) 

• Ryan M. Downey, Masaki Mizuno, Jere H. Mitchell, Wanpen Vongpatanasin and Scott A. Smith. Mineralocorticoid receptor antagonists attenuate exaggerated exercise pressor reflex responses in hypertensive rats. American Journal of Physiology Heart and Circulatory Physiology. Vol. 313, No.4: H788-794, 2017.

2016(3)

• Masaki Mizuno*, Jere H. Mitchell, and Scott A. Smith. Invited Review: The exercise pressor reflex in hypertension. The Journal of Physical Fitness and Sports Medicine. Vol. 5, No. 5: 339-347, 2016.

• Masaki Mizuno, Jere H. Mitchell, Scott Crawford, Chou-Long Huang, Naim Maalouf, Ming-Chang Hu, Orson Moe, Scott A. Smith, and Wanpen Vongpatanasin. High Dietary Phosphate Intake Induces Hypertension and Augments Exercise Pressor Reflex Function in Rats. American Journal of Physiology Regulatory, Integrative and Comparative Physiology Vol. 311, No.1: R39-48, 2016.

• Nan Liang, Jere H. Mitchell, and Scott A. Smith and Masaki Mizuno*. Exaggerated sympathetic and cardiovascular responses to stimulation of the mesencephalic locomotor region in spontaneously hypertensive rats. American Journal of Physiology Heart and Circulatory Physiology Vol. 310, No.1: H123-131, 2016.

2015(4)

• Young-tae Kim, Aswini Kanneganti, Caleb Nothnagle, Ryan Landrith, Masaki Mizuno, Muthu B.J. Wijesundara, Scott A. Smith, Mario I. Romero-Ortega. Microchannel Electrode Stimulation of Deep Peroneal Nerve Fascicles Induced Mean Arterial Depressor Response in Hypertensive Rats. Bioelectronic Medicine Vol.2: 55-62, 2015. 

• Masaki Mizuno*, Gary A. Iwamoto, Wanpen Vongpatanasin, Jere H. Mitchell, and Scott A. Smith. Dynamic exercise training prevents exercise pressor reflex overactivity in spontaneously hypertensive rats. American Journal of Physiology Heart and Circulatory Physiology Vol.309, No.5: 762-770, 2015.

• Masaki Mizuno, Ryan M. Downey, Jere H. Mitchell, Richard J. Auchus, Scott A. Smith and Wanpen Vongpatanasin. Aldosterone and Salt Loading Independently Exacerbate the Exercise Pressor Reflex in Rats. Hypertension Vol.66, No.3: 627–633, 2015.

• Scott A. Smith, Anna K. Leal, Megan N. Murphy, Ryan M. Downey and Masaki Mizuno. Muscle mechanoreflex overactivity in hypertension: a role for centrally-derived nitric oxide. Autonomic Neuroscience: Basic & Clinical Vol.188: 58-63, 2015. 

2014(3)

• Masaki Mizuno, Gary A. Iwamoto, Wanpen Vongpatanasin, Jere H. Mitchell and Scott A. Smith. Exercise training improves functional sympatholysis in spontaneously hypertensive rats through a nitric oxide dependent mechanism. American Journal of Physiology Heart and Circulatory Physiology Vol.307, No. 2: H242-251, 2014.

• Scott A. Smith, Ryan M. Downey, Jon W. Williamson and Masaki Mizuno. Autonomic Dysfunction in Muscular Dystrophy: A Theoretical Framework for Muscle Reflex Involvement. Frontiers in Physiology Vol.5, No.47: 1-9, 2014.

• Masaki Mizuno, German Lozano, Khurrum Siddique, Michel Baum, and Scott A. Smith. Enalapril attenuates the exaggerated sympathetic response to physical stress in prenatally programmed hypertensive rats. Hypertension Vol.63, No. 2: 324–329, 2014.

2013(3)

• Megan N. Murphy, Masaki Mizuno, Ryan M. Downey, Jack Squiers, Kate Squiers, Scott A. Smith. Neuronal nitric oxide synthase expression is lower in area of the nucleus tractus solitarius excited by skeletal muscle reflexes in hypertensive rats. American Journal of Physiology Heart and Circulatory Physiology Vol.304, No.11: 1547-1557, 2013.

• Toru Kawada, Meihua Li, Shuji Shimizu, Atsunori Kamiya, Kazunori Uemura, Michael J. Turner, Masaki Mizuno, and Masaru Sugimachi. High-frequency dominant depression of peripheral vagal control of heart rate in rats with chronic heart failure. Acta Physiologica Vol. 207, No. 1: 494-502, 2013.

• Masaki Mizuno, Khurrum Siddique, Michel Baum, and Scott A. Smith. Prenatal programming of hypertension induces sympathetic overactivity in response to physical stress. Hypertension Vol.61, No. 1: 180–186, 2013.

2012(2)

• Toru Kawada, Kazunori Uemura, Shuji Shimizu, Atsunori Kamiya, Michael J. Turner, Masaki Mizuno, Kenji Sunagawa and Masaru Sugimachi. Consideration on Parameter Determination of a New Model Describing Dynamic Vagal Heart Rate Control in Rats. Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 3809-3812, 2012.

• Shuji Shimizu, Tsuyoshi Akiyama, Toru Kawada, Yusuke Sata, Masaki Mizuno, Atsunori Kamiya, Toshiaki Shishido, Masashi Inagaki, Mikiyasu Shirai, Shunji Sano, and Masaru Sugimachi. Medetomidine, an α2-adrenergic agonist, activates cardiac vagal nerve through modulating baroreflex control. Circulation Journal  Vol.76, No.1: 152–159, 2012.

2011(4)

• Masaki Mizuno, Megan N. Murphy, Jere H. Mitchell, Scott A. Smith. Antagonism of the TRPv1 receptor partially corrects muscle metaboreflex overactivity in spontaneously hypertensive rats. Journal of Physiology Vol.589, No.24: 6191–6204, 2011.

• Megan N. Murphy, Masaki Mizuno, Jere H. Mitchell, and Scott A. Smith. Cardiovascular Regulation by Skeletal Muscle Reflexes in Health and Disease. American Journal of Physiology Heart and Circulatory Physiology Vol.301, No.4: 1191–1204, 2011.

• Masaki Mizuno*, Toru Kawada, Atsunori Kamiya, Tadayoshi Miyamoto, Shuji Shimizu, Toshiaki Shishido, Scott A. Smith and Masaru Sugimachi. Exercise training augments the dynamic heart rate response to vagal but not sympathetic stimulation in rats. American Journal of Physiology Regulatory, Integrative and Comparative Physiology Vol.300, No.4: 969–977, 2011.

• Masaki Mizuno, Megan N. Murphy, Jere H. Mitchell, and Scott A. Smith. Skeletal muscle reflex-mediated changes in sympathetic nerve activity are abnormal in spontaneously hypertensive rats. American Journal of Physiology Heart and Circulatory Physiology Vol. 300, No. 3: 968–977, 2011

2010(4) 

• Masaki Mizuno*, Toru Kawada, Atsunori Kamiya, Tadayoshi Miyamoto, Shuji Shimizu, Toshiaki Shishido, Scott A. Smith and Masaru Sugimachi. Dynamic characteristics of heart rate control by the autonomic nervous system in rats. Experimental Physiology Vol. 95, No.9: 919–925, 2010.

• Atsunori Kamiya, Toru Kawada, Masaki Mizuno, Shuji Shimizu, and Masaru Sugimachi. Parallel resetting of arterial baroreflex control of renal and cardiac sympathetic nerve activities during upright tilt in rabbits. American Journal of Physiology Heart and Circulatory Physiology Vol. 298, No. 6: 1966–1975, 2010

• Masaki Mizuno*, Ken Tokizawa, and Isao Muraoka. Changes in perfusion related to muscle length affect the pressor response to isometric exercise.Advances in Experimental Medicine and Biology Vol. 662: 371–378, 2010.

• Shuji Shimizu, Tsuyoshi Akiyama, Toru Kawada, Toshiaki Shishido, Masaki Mizuno, Atsunori Kamiya, Toji Yamazaki, Shunji Sano, Masaru Sugimachi. In vivo direct monitoring of sympathetic nerve activity at the sinoatrial node. Autonomic Neuroscience: Basic & Clinical  Vol.152, No. 1-2: 115–118, 2010

 2009(2)

• Shuji Shimizu, Tsuyoshi Akiyama, Toru Kawada, Toshiaki Shishido, Toji Yamazaki, Atsunori Kamiya, Masaki Mizuno, Shunji Sano, Masaru Sugimachi. In Vivo Direct Monitoring of Vagal Acetylcholine Release to the Sinoatrial Node. Autonomic Neuroscience: Basic & Clinical Vol.148, No. 1-2: 44–49, 2009.

• Toru Kawada, Masaki Mizuno, Shimizu Shuji, Kazunori, Uemura, Atsunori, Kamiya, and Masaru Sugimachi. Angiotensin II disproportionally attenuates dynamic vagal and sympathetic heart rate controls. American Journal of Physiology Heart and Circulatory Physiology Vol. 296, No. 5: H1666–1674, 2009.

2008(5)

• Masaki Mizuno*, Atsunori Kamiya, Toru Kawada, Tadayoshi Miyamoto, Shuji Shimizu, Toshiaki Shishido, and Masaru Sugimachi. Accentuated antagonism in vagal heart rate control mediated through muscarinic potassium channels. Journal of Physiological Sciences Vol. 58, No.6: 381–388, 2008.

• Masaki Mizuno*. Visualization of skeletal muscle metabolism during exercise. Training Science Vol. 20, No. 2: 91–95, 2008 (in Japanese)

• Tadayoshi Miyamoto, Toru Kawada, Yusuke Yanagiya, Tsuyoshi Akiyama, Atsunori Kamiya, Masaki Mizuno, Hiroshi Takaki, Kenji Sunagawa, and Masaru Sugimachi. Contrasting effects of presynaptic α2-adrenergic autoinhibition and pharmacologic augmentation of presynaptic inhibition on sympathetic heart rate control. American Journal of Physiology Heart and Circulatory Physiology Vol. 295, No.5: 1855–1866, 2008.

• Toru Kawada, Toji Yamazaki, Tsuyoshi Akiyama, Hirotoshi Kitagawa, Shimizu Shuji, Masaki Mizuno, Meihua Li, Masaru Sugimachi. Vagal stimulation suppresses ischemia-induced myocardial interstitial myoglobin release. Life Sciences Vol. 83, No.13-14: 490–495, 2008.

• Atsunori Kamiya, Toru Kawada, Kenta Yamamoto, Masaki Mizuno, Shuji Shimizu, and Masaru Sugimachi. Upright tilt resets dynamic transfer function of baroreflex neural arc to minify the pressure disturbance in total baroreflex control. Journal of Physiological Sciences Vol. 58, No.3: 189–198, 2008.

2007(4)

• Toru Kawada, Toji Yamazaki, Tsuyoshi Akiyama, Toshiaki Shishido, Shuji Shimizu, Masaki Mizuno, Hidezo Mori, and Masaru Sugimachi. Regional difference in ischaemia-induced myocardial interstitial noradrenaline and acetylcholine releases. Autonomic Neuroscience: Basic & Clinical, Vol. 137, No.1-2: 44–50, 2007.

• Masaki Mizuno*, Atsunori Kamiya, Toru Kawada, Tadayoshi Miyamoto, Shuji Shimizu, and Masaru Sugimachi. Muscarinic potassium channels augment dynamic and static heart rate responses to vagal stimulation. American Journal of Physiology Heart and Circulatory Physiology Vol. 293, No.3: H1564–H1570, 2007.

• Masaki Mizuno, Ken Tokizawa, and Isao Muraoka. Effects of regional cooling on vasoconstriction in the non-exercised limb during sustained knee extension exercise. Sport Science Research Vol. 4; 1–8, 2007.

• Isao Muraoka, Hasunuma Tomoko, Uesato Kazuo, Masaki Mizuno, Kuniaki Fukushima, Kazuhiro Kosuge, Hajime, Iijima, Yuji, Kumagai. Effects of activity levels of daily life on serum creatine kinase activity. Stress Science Research，Vol. 22; 41–50, 2007. (in Japanese with English abstract)

2006(4)

• Atsunori Kamiya, Toru Kawada, Masaki Mizuno, Tadayoshi Miyamoto, Kazunori Uemura, Kenjiro Seki, Shuji Shimizu, Masaru Sugimachi. Baroreflex increases correlation and coherence of muscle sympathetic nerve activity (SNA) with renal and cardiac SNAs. Journal of Physiological Sciences Vol. 56; No.5: 325–333, 2006.

• Ken Tokizawa, Masaki Mizuno, and Isao Muraoka. Forearm vascular responses to combined muscle metaboreceptor activation in the upper and lower limbs. Experimental Physiology Vol. 91; No.4: 723–729, 2006.

• Ken Tokizawa, Masaki Mizuno, Naoyuki Hayashi, and Isao Muraoka. Cardiovascular responses to extension and flexion exercises at arms and legs.European Journal of Applied Physiology Vol. 97; No.2: 249–252, 2006.

• Masaki Mizuno, Ken Tokizawa, and Isao Muraoka. Heterogeneous oxygenation in nonexercising triceps surae muscle during contralateral static contraction. European Journal of Applied Physiology Vol. 97; No.2: 181–188, 2006.

2005(2)

• Masaki Mizuno, Yuichi Kimura, Ken Tokizawa, Kenji Ishii, Keiichi Oda, Toru Sasaki, Yoshio Nakamura, Isao Muraoka, and Kiichi Ishiwata. Greater adenosine A2A receptor densities in cardiac and skeletal muscle in endurance trained men: a [11C]TMSX PET study. Nuclear Medicine and Biology Vol. 32; No.8: 831–836, 2005.

• Yayoi Kawahara, Masaki Mizuno, Takashi Iwakawa, Yoshio Nakamura, and Isao Muraoka. Relationship between oxygen supply and consumption in exercised muscle during recovery. Advances in Exercise and Sports Physiology Vol. 11; No.2: 55–60, 2005.

2004(4)

• Ken Tokizawa, Masaki Mizuno, Yoshio Nakamura, and Isao Muraoka. Passive triceps surae stretch inhibits vasoconstriction in the nonexercised limb during posthandgrip muscle ischemia. Journal of Applied Physiology Vol. 97; No.5: 1681–1685, 2004.

• Kiichi Ishiwata, Masaki Mizuno, Yuichi Kimura, Kazunori Kawamura, Keiichi Oda, Toru, Sasaki, Yoshio Nakamura, Isao Muraoka, and Kenji Ishii. Potential of [11C]TMSX for evaluation of adenosine A2A receptors in the skeletal muscle by positron emission tomography. Nuclear Medicine and Biology Vol. 31: No. 7, 949–956, 2004.

• Masaki Mizuno, Ken Tokizawa, Takashi Iwakawa, and Isao Muraoka. Inflection points of cardiovascular responses and oxygenation are correlated in the distal but not the proximal portions of muscle during incremental exercise. Journal of Applied Physiology Vol. 97: No.3, 867–873, 2004.

• Ken Tokizawa, Masaki Mizuno, Yoshio Nakamura, and Isao Muraoka. Venous occlusion to the lower limb attenuates vasoconstriction in the non-exercised limb during post-handgrip muscle ischemia. Journal of Applied Physiology Vol. 96: No.3, 981–984, 2004.

2003(4)

• Masaki Mizuno, Yuichi Kimura, Takashi Iwakawa, Keiichi Oda, Kenji Ishii, Kiichi Ishiwata, Yoshio Nakamura, and Isao Muraoka. Regional differences in blood volume and blood transit time in resting skeletal muscle. Japanese Journal of Physiology, Vol. 53: No. 6, 467–470, 2003.

• Masaki Mizuno, Yuichi Kimura, Takashi Iwakawa, Keiichi Oda, Kenji Ishii, Kiichi Ishiwata, Yoshio Nakamura, and Isao Muraoka. Regional differences in blood flow and oxygen consumption in resting muscle and their relationship during recovery from exhaustive exercise. Journal of Applied Physiology Vol. 95: No.6, 2204–2210, 2003.

• Ken Tokizawa, Masaki Mizuno, Yoshio Nakamura, Isao Muraoka. Effects of exercise intensity and low-pressure occlusion in calf on cardiovascular responses during concomitant forearm and calf exercise. Japan Journal of Physical Education Health and Sport Sciences, Vol.48: No. 2, 225–235, 2003 (in Japanese with English abstract)

• Yayoi Kawahara, Masaki Mizuno, Kazunobu Ohmori, Yoshio Nakamura, Isao Muraoka. Muscle oxygenation kinetics after intensive bicycle exercise. Japan Journal of Exercise and Sports Physiology, Vol. 10: No.1, 9–16, 2003 (in Japanese with English abstract)

2000(1)

• Kazunobu Ohmori, Shin-ya. Kuno, Yuichi Kimura, Masaki Mizuno, Yoshio Nakamura, Isao Muraoka, Fukio Ohta, Masahiro Mishina, Hinako Toyama, and Michio Senda. Assessment of regional change of glucose metabolism after high-intensity exercise inn exercised muscle using positron emission tomography. Advances in Exercise and Sports Physiology, Vol. 6, No.3 pp.81–84, 2000. 

2026

• Amane Hori, Ayumi Fukazawa, Norio Hotta. Toru Kawada, Han-Kyul Kim, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and  Masaki Mizuno. TRPV4 and Piezo channel inhibition in the isolated carotid sinus comparably suppresses baroreflex function and acts synergistically at high arterial pressures in healthy male rats. 4th Annual Meeting American Physiological Summit, Minneapolis, USA, April, 2026.

• Ayumi Fukazawa, Norio Hotta, Amane Hori, Han-Kyul Kim, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and  Masaki Mizuno. Piezo1 channels play a crucial role as mechanical sensors in dorsal root ganglion neurons innervating hindlimb muscle in rats. 4th Annual Meeting American Physiological Summit, Minneapolis, USA, April, 2026. The NCAR Research Recognition Award

• Amane Hori, Ayumi Fukazawa, Norio Hotta. Toru Kawada, Han-Kyul Kim, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and  Masaki Mizuno. TRPV4 channel inhibitor attenuates the arterial baroreflex function to the same extent as Piezo channels inhibitor and the two act synergistically within the high-pressure range in healthy male rats. 103th Annual Meeting of Physiological Society of Japan, Tokyo, Japan, March, 2026.

2025

• Rie Ishizawa, Norio Hotta, Han-Kyul Kim, Juan A. Estrada, Ayumi Fukazawa, Gary A. Iwamoto, Wanpen Vongpatanasin, Scott A. Smith, and Masaki Mizuno. Gut-endotoxin lipopolysaccharide sensitizes the mechanosensitive muscle afferents responsiveness via Piezo1 channels. 36th International Symposium on the Autonomic Nervous System, Clearwater Beach, FL, November 2025.

• Han-Kyul Kim, Ayumi Fukazawa, Gary A. Iwamoto, Scott A. Smith, Masaki Mizuno, and Wanpen Vongpatanasin. 1,3-Butanediol Administration Recapitulates the Anti-Hypertensive Effect of Dapagliflozin in Spontaneously Hypertensive Rats. 3rd Annual Meeting American Physiological Summit, Baltimore, USA, April, 2025.

• Amane Hori, Toru Kawada, Norio Hotta, Ayumi Fukazawa, Juan A. Estrada, Han-Kyul Kim, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and Masaki Mizuno. Gadolinium administration into vascularly isolated carotid sinus regions suppresses the neural arc of arterial baroreflex function in anesthetized healthy male rats. 3rd Annual Meeting American Physiological Summit, Baltimore, USA, April, 2025. The NCARnation Trainee Presentation Award Nominee

• Ayumi Fukazawa, Norio Hotta, Hoda Yeganehjoo, Amane Hori, Han-Kyul Kim, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and Masaki Mizuno. Blunted pressor and cardioaccelerator responses to electrical stimulation of skeletal muscle afferent nerves in male rats with sporadic Alzheimer’s disease. 3rd Annual Meeting American Physiological Summit, Baltimore, USA, April, 2025.  Henry Pickering Bowditch Lecture Awardees Abstracts of Distinction

2024

• Amane Hori, Toru Kawada, Norio Hotta, Ayumi Fukazawa, Juan A. Estrada, Han-Kyul Kim, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and Masaki Mizuno. Blockade of insulin receptor signaling in the brain impairs arterial baroreflex function in rats. 71th Annual Congress of the American College of Sports Medicine, Boston, USA, May, 2024.

• Ayumi Fukazawa, Amane Hori, Juan Estrada, Han-Kyul Kim, Gary A. Iwamoto, Norio Hotta, Scott A. Smith, Wanpen Vongpatanasin, and Masaki Mizuno. Insulin enhances the activity of TRPV4 channels in rat small dorsal root ganglion neurons. 71th Annual Congress of the American College of Sports Medicine, Boston, USA, May, 2024.

• Han-Kyul Kim, Juan A. Estrada, Ayumi Fukazawa, Amane Hori, Gary A. Iwamoto, Masaki Mizuno, Scott A. Smith, and Wanpen Vongpatanasin. Exercise Pressor Reflex Function Is Exacerbated in Decerebrate Adenine-Induced Chronic Kidney Disease Rats. 2nd Annual Meeting American Physiological Summit, Long Beach, USA, April, 2024.

• Juan Estrada, Han-Kyul Kim, Ayumi Fukazawa, Amane Hori, Rie Ishizawa, Norio Hotta, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and Masaki Mizuno. Disrupted phosphorylated phosphoinositide 3-kinase in the NTS of type 2 diabetic rats. 2nd Annual Meeting American Physiological Summit, Long Beach, USA, April, 2024.

•  Ayumi Fukazawa, Amane Hori, Juan Estrada, Han-Kyul Kim, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and Masaki Mizuno. Amyloid β reduces mechanical sensation through attenuating TRPV4 channels in rat small dorsal root ganglia neurons.  2nd Annual Meeting American Physiological Summit, Long Beach, USA, April, 2024.

2023

• Kenta Yamamoto , Riko Kai, Masaki Mizuno. Daily physical activity enhances efficacy of treatment with SGLT2 inhibitors in patients with type 2 diabetes. 28th Annual Congress of the European College of Sport Science, Paris, France, July, 2023.

• Ayumi Fukazawa, Amane Hori, Norio Hotta, Kimiaki Katanosaka, Juan Estrada, Rie Ishizawa, Han-Kyul Kim, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and Masaki Mizuno. Antagonism of TRPV4 channels decreases neural discharge and pressor responses to mechanical stimulation in rats.  70th Annual Congress of the American College of Sports Medicine, Denver, USA, May-June, 2023.

• Juan Estrada, Rie Ishizawa, Han-Kyul Kim, Norio Hotta, Ayumi Fukazawa, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and Masaki Mizuno. Speed of mechanical loading determines the cardiovascular and sympathetic responses to muscle mechanoreflex in rats.  70th Annual Congress of the American College of Sports Medicine, Denver, USA, May-June, 2023.

• Ayumi Fukazawa, Amane Hori, Norio Hotta, Kimiaki Katanosaka, Juan Estrada, Rie Ishizawa, Han-Kyul Kim, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and Masaki Mizuno. Antagonism of TRPV4 channels decreases mechanically activated current in rat small dorsal root ganglion neurons  1st Annual Meeting American Physiological Summit, Long Beach, USA, April, 2023.

• Juan Estrada, Rie Ishizawa, Han-Kyul Kim, Ayumi Fukazawa, Gary A. Iwamoto, Scott A Smith, Wanpen Vongpatanasin, and Masaki Mizuno.  Intracerebroventricular injection of insulin normalizes the augmented exercise pressor reflex in type II diabetic rats. 1st Annual Meeting American Physiological Summit, Long Beach, USA, April, 2023. Abstract distinction Award

• Juan A. Estrada, Norio Hotta, Han-Kyul Kim, Rie Ishizawa, Ayumi Fukazawa, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, and Masaki Mizuno. The exercise pressor reflex activates nuclear c-Fos translocation within insulin receptor positive neurons of the nucleus tractus solitarius in Sprague-Dawley rats. 1st Annual Meeting American Physiological Summit, Long Beach, USA, April, 2023.

• Amane Hori, Teruaki Nasu, Ryuji Saito, Kimiaki Katanosaka, Kazue Mizumura, Masaki Mizuno, and Norio Hotta. The ASIC3 inhibitor APETx2 attenuates the exaggerated muscle mechanoreflex in rats with repeated cold stress. 100th Anniversary Annual Meeting of Physiological Society of Japan, Kyoto, Japan, March, 2023.

• Rie Ishizawa, Norio Hotta, Han-Kyul Kim, Gary A. Iwamoto, Wanpen Vongpatanasin, Scott A. Smith and Masaki Mizuno. Alterations of Piezo-1 channel activity in group IV muscle afferents  of Type 2 diabetic rats . 100th Anniversary Annual Meeting of Physiological Society of Japan, Kyoto, Japan, March, 2023.

2022

• Rie Ishizawa, Norio Hotta, Han-Kyul Kim, Gary A. Iwamoto, Wanpen Vongpatanasin, Jere H. Mitchell, Scott A. Smith and Masaki Mizuno. Yoda1-induced Piezo1 Channel Activity In Group Iv Muscle Afferents Of Type 2 Diabetic Rats . 69th Annual Congress of the American College of Sports Medicine, San Diego, USA, June, 2022.

• Masaki Mizuno, Rie Ishizawa, Norio Hotta, Han-Kyul Kim, Gary A. Iwamoto, Wanpen Vongpatanasin, Scott A. Smith, and Jere H. Mitchell. Frequency Dependent Neural Discharge Of Group Iv Muscle Afferents To Sinusoidal Mechanical Stimulation In Rats. 69th Annual Congress of the American College of Sports Medicine, San Diego, USA, June, 2022.

• Juan A. Estrada, Norio Hotta, Gary A. Iwamoto, Han-Kyul Kim, Wanpen Vongpatanasin, Jere H. Mitchell, Scott A. Smith, Masaki Mizuno. Brain Insulin Receptor Antagonism Augments the Blood Pressure Response to Activation of the Exercise Pressor Reflex. 69th Annual Congress of the American College of Sports Medicine, San Diego, USA, June, 2022.

• Ayumi Fukazawa, Amane Hori, Hotta Norio, Juan Estrada, Kimiaki Katanosaka, Kazue Mizumura, Jun Sato, Rie Ishizawa, Han-Kyul Kim, Gary A. Iwamoto, Wanpen Vongpatanasin, Jere H. Mitchell, Scott A. Smith, and Masaki Mizuno. Intramuscular insulin administration potentiates sympathetic and pressor responses to capsaicin in rats. Experimental Biology 2022, Philadelphia, USA, April, 2022. The NCARnation Trainee Presentation Award Nominee

• Amane Hori, Teruaki Nasu, Ryuji Saito, Kimiaki Katanosaka, Kazue Mizumura, Masaki Mizuno, Norio Hotta. Exposure to Repeated Cold Stress Influences Sympathetic and Cardiovascular Responses to Muscle Stretch in Decerebrated Rats. Experimental Biology 2022, Philadelphia, USA, April, 2022.

• Han-Kyul Kim, Rie Ishizawa, Ayumi Fukazawa, Masaki Mizuno, Jere H. Mitchell, Scott A. Smith, and Wanpen Vongpatanasin. Dapagliflozin Attenuates Sympathetic and Pressor Responses to Stress in Young Prehypertensive Spontaneously Hypertensive Rats. Experimental Biology 2022, Philadelphia, USA, April, 2022.

2021

• Rie Ishizawa, Norio Hotta, Han-Kyul Kim, Gary A. Iwamoto, Jere H. Mitchell, Scott A. Smith, Wanpen Vongpatanasin, Masaki Mizuno. High-glucose exposure potentiates the response to capsaicin-induced TRPV1 activation in group IV muscle afferents. 68th Annual Congress of the American College of Sports Medicine, Virtual, USA, June, 2021.

• Han-Kyul Kim, Masaki Mizuno, Jere H. Mitchell, Johanne V. Pastor, Orson W. Moe, Scott A. Smith, Beverly A. Rothermel, and Wanpen Vongpatanasin. Central Calcineurin Plays a Role in Skeletal Muscle Reflex Overactivity Induced by High Dietary Phosphate Intake in Rats. Experimental Biology 2021, Virtual, USA, April, 2021.

• Kanji Matsukawa, Gary A. Iwamoto, Jere H. Mitchell, Masaki Mizuno, Han-Kyul Kim, Jon W. Williamson, and Scott A. Smith. Exaggerated pressor and sympathetic nerve responses during spontaneously-occurring motor activity in decerebrate spontaneously hypertensive rats. Experimental Biology 2021, Virtual, USA, April, 2021.

• Rie Ishizawa, Norio Hotta, Han-Kyul Kim, Gary A. Iwamoto, Jere H. Mitchell, Scott A. Smith, Wanpen Vongpatanasin, Masaki Mizuno. Role of Piezo channels in group IV muscle afferent fiber mechanosensation in rats. Experimental Biology 2021, Virtual, USA, April, 2021.

2020

• Juan A. Estrada, Norio Hotta, Han-Kyul Kim, Rie Ishizawa, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, Jere H. Mitchell, and Masaki Mizuno. Insulin receptor blockade in the nucleus tractus solitarius augments exercise pressor reflex function in normal rats. Integrative Physiology of Exercise, Virtual, November, 2020.

• Amane Hori, Norio Hotta, Kimiaki Katanosaka, Kazue Mizumura, Jun Sato, Rie Ishizawa, Han-Kyul Kim, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, Jere H. Mitchell, and Masaki Mizuno. Insulin sensitizes the response to capsaicin in small dorsal root ganglion neurons and thin fiber muscle afferents. Integrative Physiology of Exercise, Virtual, November, 2020. Poster Presentation Award

• Han-Kyul Kim, Masaki Mizuno, Gary A Iwamoto, Rie Ishizawa, Jere H Mitchell, Johanne V Pastor, Orson W Moe, Scott A Smith, Wanpen Vongpatanasin. Brain Fibroblast Growth Factor Receptor 4 Stimulation is Involved in High Phosphate Diet-Induced Skeletal Muscle Reflex Overactivation in Rats. American Heart Association Scientific Sessions 2020, Virtual, November, 2020.

• Rie Ishizawa, Han-Kyul Kim, Norio Hotta, Gary A. Iwamoto, Wanpen Vongpatanasin, Jere H. Mitchell, Scott A. Smith, and Masaki Mizuno. Sensory Neuron Sensitization By Pkc-induced Trpv1 Phosphorylation In Type 2 Diabetic Rats. 67th Annual Congress of the American College of Sports Medicine, San Francisco (Virtual), USA, May-June, 2020.

• Han-Kyul Kim, Rie Ishizawa, Norio Hotta, Gary A. Iwamoto, Wanpen Vongpatanasin, Jere H. Mitchell, Scott A. Smith, and Masaki Mizuno. Skeletal Muscle Reflex-Induced Dysregulation of Sympathetic Nerve Activity in Type 1 Diabetic Rats. Experimental Biology 2020, San Diego (Virtual), USA, April, 2020.

• Rie Ishizawa, Han-Kyul Kim, Norio Hotta, Gary A. Iwamoto, Wanpen Vongpatanasin, Jere H. Mitchell, Scott A. Smith, and Masaki Mizuno. Sensitization of group lV skeletal muscle afferents in type 1 diabetic rats. Experimental Biology 2020, San Diego (Virtual), USA, April, 2020. 

• Norio Hotta, Amane Hori, Yukiko Okamura, Reizo Baba, Hidehiro Watanabe, Jun Sugawara, Han-Kyul Kim, Rie Ishizawa, Gary A. Iwamoto, Wanpen Vongpatanasin, Jere H. Mitchell, Scott A. Smith, and Masaki Mizuno. Insulin resistance is an independent factor to determine an exaggerated pressor response to ischemic rhythmic handgrip in non–diabetic older adults. Experimental Biology 2020, San Diego (Virtual), USA, April, 2020.

2019

• Rie Ishizawa, Han-Kyul Kim, Norio Hotta, Gary A. Iwamoto, Wanpen Vongpatanasin, Jere H. Mitchell, Scott A. Smith, and Masaki Mizuno. An exaggerated muscle metaboreflex in diabetic rats is mediated by potentiated skeletal muscle afferent responsiveness. 66th Annual Congress of the American College of Sports Medicine, Orlando USA, May-June, 2019.

• Han-Kyul Kim, Masaki Mizuno, Gary A. Iwamoto, Rie Ishizawa, Jere H. Mitchell, Scott A. Smith and Wanpen Vongpatanasin. Intracerebroventricular Administration of Fibroblast Growth Factor Receptor Inhibitor Attenuates High Phosphate Diet-Induced Exercise Pressor Reflex Overactivation in Rats. Experimental Biology 2019, Orlando, USA, April, 2019. 

• Norio Hotta, Kimiaki Katanosaka, Kazue Mizumura, Rie Ishizawa, Jere H. Mitchell, Scott A. Smith, and Masaki Mizuno. Responses to Mechanical and Chemical Stimuli are Augmented by Insulin Administration in Neurons Innervating Skeletal Muscle. Experimental Biology 2019, Orlando, USA, April, 2019. 

• Rie Ishizawa, Han-Kyul Kim, Norio Hotta, Gary A. Iwamoto, Wanpen Vongpatanasin, Jere H. Mitchell, Scott A. Smith, and Masaki Mizuno. An Exaggerated Muscle Mechanoreflex in Type 2 Diabetic Rats Is Mediated by Potentiated Skeletal Muscle Afferent Discharge to Mechanical Stimulation. Experimental Biology 2019, Orlando, USA, April, 2019. Featured Topic - Regulation of Muscle Sympathetic Outflow during Exercise.

• Rie Ishizawa, Norio Hotta, Gary A. Iwamoto, Han-Kyul Kim, Wanpen Vongpatanasin, Jere H. Mitchell, Scott A. Smith and Masaki Mizuno. Enhanced muscle afferent responses to mechanical/chemical stimuli in type 2 diabetic rats in vitro. 9th FAOPS, Kobe, JAPAN March, 2019.

2018

• Norio Hotta, Kimiaki Katanosaka, Kazue Mizumura, Jere H. Mitchell, Scott A. Smith and Masaki Mizuno. Insulin Potentiates Neuronal Responses to Chemical Stimulation in Thin Muscle Afferents and Dorsal Root Ganglia. 65th Annual Congress of the American College of Sports Medicine, Minneapolis USA, May-June, 2018.

• Norio Hotta, Kimiaki Katanosaka, Kazue Mizumura, Jere H. Mitchell, Scott A. Smith and Masaki Mizuno. Neural Responses to Mechanical Stimulation in Thin Muscle Afferents and Dorsal Root Ganglia are Sensitized by Insulin. Experimental Biology 2018, San Diego, USA, April, 2018. Featured Topic - Battle of the Reflexes: Chemo- versus Baroreflexes during Physiological Stressors, Aging and Cardiovascular Disease

2017

• Masaki Mizuno, Jere H. Mitchell, and Scott A. Smith. Exaggerated Cardiovascular Response to Muscle Mechanoreflex Activation in Type 2 Diabetic Rats. 64th Annual Congress of the American College of Sports Medicine, Denver, USA, May-June, 2017.

• Masaki Mizuno, Jere H. Mitchell, and Scott A. Smith. Exaggerated sympathetic and pressor responses to exercise pressor reflex activation are attenuated by intracerebroventricular insulin administration in type 2 diabetic rats. Experimental Biology 2017, Chicago, USA, April, 2017.

2016

• Masaki Mizuno, Scott Crawford, Samuel Rosengarden, Jere H. Mitchell, Scott A. Smith and Wanpen Vongpatanasin. Excess phosphorus intake potentiates the skeletal muscle mechanoreflex and metaboreflex in rats. 63th Annual Congress of the American College of Sports Medicine, Boston, USA, May-June, 2016.

• Masaki Mizuno, Seth H. Holwerda, Jere H. Mitchell, Scott A. Smith and Paul J. Fadel. Enhanced skeletal muscle metaboreflex activation in type 2 diabetes. Experimental Biology 2016, San Diego, USA, April, 2016.

• Masaki Mizuno, Scott Crawford, Cooper Carnahan, Jere H. Mitchell, Scott A. Smith, Wanpen Vongpatanasin. High inorganic phosphate diet augments the sympathetic response to exercise pressor reflex activation in rats. Experimental Biology 2016, San Diego, USA, April, 2016.

2015

• Masaki Mizuno, Gary A. Iwamoto, Wanpen Vongpatanasin, Jere H. Mitchell, and Scott A. Smith. Exercise training ameliorates sympathetic overactivity in response to muscle metaboreflex stimulation in spontaneously hypertensive rats. 62th Annual Congress of the American College of Sports Medicine, San Diego, USA, May, 2015.

• Masaki Mizuno, Gary A. Iwamoto, Wanpen Vongpatanasin, Jere H. Mitchell, and Scott A. Smith. Voluntary exercise training attenuates the enhanced sympathetic responses to muscle mechanoreflex activation in spontaneously hypertensive rats. Experimental Biology 2015, Boston, USA, March, 2015.

2014 

• Masaki Mizuno, Gary A. Iwamoto, Wanpen Vongpatanasin, Jere H. Mitchell, and Scott A. Smith. Impaired functional sympatholysis in spontaneously hypertensive rats is normalized by exercise training via a nitric oxide mechanism. 61th Annual Congress of the American College of Sports Medicine, Orland, USA, May, 2014.

• Masaki Mizuno, Ryan M. Downey, Jere H. Mitchell, Scott A. Smith, and Wanpen Vongpatanasin. High salt intake and aldosterone independently augment the exercise pressor reflex in rats. Experimental Biology 2014, San Diego, USA, April, 2014.        

2013

• Masaki Mizuno, Ryan Downey, Jere H. Mitchell, and Scott A. Smith. Alterations in the Cardiovascular Response to Central Command and Exercise Pressor Reflex Activation in Type 2 Diabetic Rats. 60th Annual Congress of the American College of Sports Medicine, Indianapolis, USA, May, 2013.

• Masaki Mizuno, German Lozano, Khurrum Siddique, Michel Baum, and Scott A. Smith. Enalapril attenuates the exaggerated sympathetic response to physical stress in prenatally programmed hypertensive rats. Experimental Biology 2013, Boston, USA, April, 2013.

2012

• Masaki Mizuno, Khurrum Siddique, Michel Baum, Scott A. Smith. Prenatal Programming of Hypertension by Dietary Protein Deprivation Alters Skeletal Muscle Reflex Function in Rats. 59th Annual Congress of the American College of Sports Medicine, San Francisco, USA, June, 2012.

• Masaki Mizuno, Ryan Downey, Jere H. Mitchell, and Scott A. Smith. Brain insulin modulates the cardiovascular response to central command and exercise pressor reflex stimulation in rats. Experimental Biology 2012, San Diego, USA, April, 2012

2011

• Masaki Mizuno, Megan N. Murphy, Jere H. Mitchell, and Scott A. Smith. Exaggerated Sympathetic Responses to Metaboreflex Activation during Ischemic Muscle Contraction in Hypertensive Rats. 58th Annual Congress of the American College of Sports Medicine, Denver, USA, June, 2011.

• Masaki Mizuno, Megan N. Murphy, Jere H. Mitchell, and Scott A. Smith. Skeletal muscle metaboreflex overactivity is mediated by the TRPv1 receptor in spontaneously hypertensive rats. Experimental Biology 2011, Washington, USA, April, 2011

2010

• Masaki Mizuno, Megan N. Murphy, Jere H. Mitchell, and Scott A. Smith. Sympathetic Nerve Responses to Activation of Chemically-Sensitive Skeletal Muscle Afferent Fibers in Hypertensive Rats. 57th Annual Congress of the American College of Sports Medicine, Baltimore, USA, June, 2010.

• Masaki Mizuno, Megan N. Murphy, Jere H. Mitchell, and Scott A. Smith. The sympathetic response to activation of the skeletal muscle mechanoreflex is enhanced in spontaneously hypertensive rats. Experimental Biology 2010, Anaheim, USA, April, 2010.

2008

• Masaki Mizuno, Ken Tokizawa, and Isao Muraoka. Changes in perfusion related to muscle length affect the pressor response to isometric exercise.International Society of Oxygen Transport to Tissue 2008, Sapporo, Japan, July, 2008.

• Masaki Mizuno, Atsunori Kamiya, Toru Kawada, Masaru Sugimachi. Muscarinic potassium channels play a significant role in the negative chronotropic response with or without background sympathetic tone. Experimental Biology 2008, San Diego, USA, April, 2008.

2004

• Masaki Mizuno, Ken Tokizawa, Takashi Iwakawa, Isao Muraoka. Relationship between inflection point of cardiovascular responses and that of muscle deoxygenation in exercising muscle during incremental static exercise. 9th Annual Congress of the European College of Sport Science, Clermont-Ferrand, France, July, 2004

• Masaki Mizuno, Yuichi Kimura, Kenji Ishii, Keiichi Oda, Toru Sasaki, Kazunori Kawamura, Kiichi Ishiwata, Isao Muraoka. Effects of endurance training on adenosine A2A receptor density in myocardium and skeletal muscle. 51st Annual Congress of the American College of Sports Medicine, Indianapolis, USA, June, 2004.

2001

• Masaki Mizuno, Yuichi Kimura, Kazunobu Ohmori, Yoshio Nakamura, Isao Muraoka. Recovery of hemodynamics after high-intensity exercise with positron emission tomography. 6th Annual Congress of the European College of Sport Science, Cologne, German, July, 2001.

• Masaki Mizuno. Tuning the autonomic symphony: central insulin signaling and autonomic control at rest and during exercise. 36th International Symposium on the Autonomic Nervous System, Clearwater Beach, FL, November 2025.

• Masaki Mizuno. Amyloid beta and autonomic dysfunction., 257th Sports Sciences Meeting, Waseda University, Tokorozawa, Japan, October 2025.

• Masaki Mizuno and Ayumi Fukazawa. Amyloid beta and alterations in mechanical sensation., Symposium (organizer and speaker), 78th Annual meeting of Japan Society of Neurovegetative Research, Nagoya, Japan, October 2025.

• Masaki Mizuno. Amyloid beta and autonomic nervous system. AIST Shikoku Center Research Seminar, Takamatsu, Japan, October 2025.

• Masaki Mizuno. Central Insulin Resistance: Impact on Autonomic Cardiovascular Control During Exercise. 2nd Annual Hardin Translational Cardiovascular Research Symposium, Arlington, TX, June, 2025.

• Masaki Mizuno. Be Ambitious With Your Career Goals. Special lecture, Graduate School of Life and Health Sciences, Chubu University, Kasugai, Japan, November, 2024.

• Masaki Mizuno. Be Ambitious With Your Career Goals. Special lecture, Graduate School of Physical Education, National Institute of Fitness and Sports in Kanoya, Kagoshima, Japan, November, 2024.

• Masaki Mizuno. Research Mindset, SHEEP seminar, School of Physical Education, National Institute of Fitness and Sports in Kanoya, Kagoshima, Japan, November, 2024.

• Masaki Mizuno. Open up career paths for young scientists and graduate students through a variety of experiences. Symposium (organizer), 32nd Congress of Japan Society of Exercise and Sports Physiology, Kanazawa, Japan, August, 2024.

• Masaki Mizuno. Frontiers of autonomic cardiovascular control during exercise. Symposium (organizer and speaker), 32nd Congress of Japan Society of Exercise and Sports Physiology, Kanazawa, Japan, August, 2024.

• Masaki Mizuno. An integrative approach to better understand the mechanisms of the exercise pressor reflex in health and disease. Symposium (speaker), 13th Congress of The International Society for Autonomic Neuroscience, Birmingham, UK, July, 2024.

• Masaki Mizuno. Exercise pressor reflex in vivo humans and animals studies. Symposium (speaker), Annual Meeting of Japanese Society of Physical Fitness and Sports Medicine, Tokyo, September, 2023.

• Masaki Mizuno. Amyloid beta and blood pressure regulation. Seminar, Research Institute for Life and Health Sciences at Chubu University, Kasugai, Japan, September, 2023.

• Masaki Mizuno. Impact of cardiovascular disease on sensory afferent function during physical exercise. Symposium (speaker), 100th  Anniversary Meeting of Physiological Society of Japan, Kyoto, Japan, March, 2023.

• Masaki Mizuno. Insulin resistance and muscle sensory neuropathy. Seminar, Research Institute for Life and Health Sciences at Chubu University, Virtual, September, 2021.

• Rie Ishizawa and Masaki Mizuno. Exaggerated cardiovascular control during exercise in diabetes. Symposium (organizer and speaker), 76th Annual Meeting of Japanese Society of Physical Fitness and Sports Medicine, Virtual, September, 2021.

• Hoda Yeganehjoo and Masaki Mizuno. Neuroprotective and metabolic effects of geranylgeraniol and tocotrienol in steptozoticin-induced Alzheimer’s rat models. CAPRA INTERDISCIPLINARY HEALTHCARE SYMPOSIUM “Collaborate: New Frontiers in Neurological Research”, Dallas, USA, February, 2020.

• Staci Shealin and Masaki Mizuno. The impact of exercise intensity on brain derived neurotrophic factor in Parkinson’s disease: a pilot study, from the bench to the clinic”. CAPRA INTERDISCIPLINARY HEALTHCARE SYMPOSIUM “Collaborate: New Frontiers in Neurological Research”, Dallas, USA, February, 2020.

• Masaki Mizuno. Targeting insulin resistance to improve abnormal cardiovascular regulation in diabetes. Faculty Development Seminar, Teikyo Heisei University, Tokyo, Japan, March, 2019.

• Masaki Mizuno. Panel Discussion-Research abroad. Evening Seminar, 74th Annual Meeting of Japanese Society of Physical Fitness and Sports Medicine, Tsukuba, Japan, September, 2019.

• Masaki Mizuno. Role of insulin in cardiovascular control during exercise. Special Lecture, 33rd Annual Respiratory Meeting, Tsukuba, Japan, September, 2019.

• Masaki Mizuno. Blood pressure control in lifestyle disease. Special Seminar, Joint seminar between National Institute of Advanced Industrial Science and Technology (AIST) and University of Tsukuba, Tsukuba, Japan, September, 2019.

• Masaki Mizuno. Research abroad and research career path in US. Graduate School Research Seminar, The University of Tokyo, Tokyo, Japan, April, 2019.

• Masaki Mizuno. Targeting insulin resistance to ameliorate abnormal cardiovascular control in diabetes. Research Seminar, Kobe University, Kobe, Japan, March, 2019.

• Masaki Mizuno. Targeting insulin resistance to improve abnormal cardiovascular control in diabetes. Faculty Development Seminar, Hiroshima University, Hiroshima, Japan, March, 2019.

• Masaki Mizuno. Targeting insulin resistance to improve exaggerated circulatory control in diabetes. Graduate School Seminar, Nagoya University, Nagoya, Japan, March, 2019.

• Masaki Mizuno and Hoda Yeganehjoo. Targeting insulin resistance to improve abnormal cardiovascular control in diabetes. CAPRA INTERDISCIPLINARY HEALTHCARE SYMPOSIUM “Collaborate: Using Team Approaches to Advance Research on Chronic Conditions”, Dallas, USA, February, 2019.

• Hoda Yeganehjoo and Masaki Mizuno. Investigating the Potential Impacts of Natural Dietary Components of Improving Cognitive Function and Protein Biomarkers of Alzheimer’s Disease in Rat Models. CAPRA INTERDISCIPLINARY HEALTHCARE SYMPOSIUM “Collaborate: Interdisciplinary Bench Science and Clinical Research”, Dallas, USA, February, 2018.

• Staci Shealin and Masaki Mizuno. Impact of Exercise Intensity on Brain Derived Neurotrophic Factor in Parkinson’s Disease: From the Bench to the Clinic. CAPRA INTERDISCIPLINARY HEALTHCARE SYMPOSIUM “Collaborate: Transforming Medical Education and Patient Care Through InterProfessional Research”, Dallas, USA, February, 2017.

• Masaki Mizuno. Dysfunctional neural control of circulation during physical activity in hypertension.  Graduate School Seminar, Juntendo University, Inzai, Japan, July, 2014.

• Masaki Mizuno. Abnormal neural regulation of circulation during physical activity in hypertension. Graduate School Seminar, Toyo University, Tsurugashima, Japan, July, 2014.

• Masaki Mizuno. Neural control of circulation during physical exercise and its dysfunction in hypertension. Graduate School Seminar, The University of Tokyo, Tokyo, Japan, July, 2014.

• Masaki Mizuno. Dysfunctional autonomic regulation of circulatory system during exercise in hypertension. 137th Sports Sciences Meeting, Waseda University, Tokorozawa, Japan, July, 2014.

• Masaki Mizuno. The mechanisms for abnormal neural control of circulation during exercise in hypertension. Research Seminar, Japan Women's College of Physical Education, Tokyo, Japan, July, 2014.

• Masaki Mizuno. Abnormal neural control of circulation during exercise in hypertension. Research Seminar, Hiroshima University, Hiroshima, Japan, July, 2014.

• Masaki Mizuno. Neural control of circulation during exercise in hypertension. Graduate School Seminar, Nagoya University, Nagoya, Japan, June, 2014.

• Masaki Mizuno. Autonomic heart rate control using systems analysis. 48th Sports Sciences Meeting, Waseda University, Tokorozawa, Japan, July, 2007.

• Masaki Mizuno. Evaluation of changes in peripheral circulation during exercise using PET and NIRS. Symposium: Bioimaging in physical fitness and sports medicine, 61th Japanese Society of Physical Fitness and Sports Medicine, Kobe, Japan, September, 2006.

• Masaki Mizuno and Isao Muraoka. Evaluation of heterogeneities in skeletal muscle perfusion and metabolism and their physiological roles during exercise. International Sports Science Network Forum in Nagano, Matsumoto, Japan, November, 2004.

• Nan Liang, Gary A. Iwamoto, Ryan M. Downey, Jere H. Mitchell, Scott A. Smith and Masaki Mizuno*. The pressor response to concurrent stimulation of the mesencephalic locomotor region and peripheral sensory afferents is attenuated in normotensive but not hypertensive rats. In: Cardiovascular Adjustments and Adaptations to Exercise: From the Athlete to the Patient. Frontiers Media SA. doi: 10.3389/978-2-88963-633-4, Crisafulli, A., Piepoli, M., Thijssen, D. H. J., Bassareo, P. P., eds., 2020.

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