Traditional pharmacology often overlooks the vast influence of the gut microbiome. Our lab's multi-omics platform integrates transcriptomics, metabolomics, and metagenomics to build a complete picture. This allows us to identify how phytochemicals truly work in the body, paving the way for next-generation precision therapeutics. 

Why does a drug work for one person but not another? The answer often lies in our unique genetic blueprint. Our research utilizes advanced models, including genetically diverse Diversity Outbred mice, to simulate human genetic variation. This powerful approach allows us to unravel how diet and medications interact with host genetics, with the ultimate goal of designing rational interventions to combat geriatric diseases like sarcopenia, NASH, and cancer cachexia.