Ensure you have Matlab (tested with >2013b) installed, with the data acquisition and image acquisition toolboxes.
Clone or download package from: https://github.com/deisseroth-lab/multifiber
For lightweight, do-it-yourself software: the only functions really necessary are the ability to record camera frames and to control the illumination. Then, post processing consists of selecting an ROI in within each fiber of the bundle and extracting the time series.